headshot of Sang Ho Ye

Sang Ho Ye

Research Assistant Professor
Bioengineering Department

about

Kim, S., Nowicki, K.W., Kohyama, K., Mittal, A., Ye, S., Wang, K., Fujii, T., Rajesh, S., Cao, C., Mantena, R., Barbuto, M., Jung, Y., Gross, B.A., Friedlander, R.M., & Wagner, W.R. (2024). Development of an Injectable, ECM-Derivative Embolic for the Treatment of Cerebral Saccular Aneurysms. Biomacromolecules, 25(8), 4879-4890.American Chemical Society (ACS). doi: 10.1021/acs.biomac.4c00321.

Ye, S.H., Orizondo, R.A., De, B.N., Kim, S., Frankowski, B.J., Federspiel, W.J., & Wagner, W.R. (2024). Epoxy silane sulfobetaine block copolymers for simple, aqueous thromboresistant coating on ambulatory assist lung devices. J Biomed Mater Res A, 112(1), 99-109.Wiley. doi: 10.1002/jbm.a.37619.

Emery, S.P., Greene, S., Elsisy, M., Chung, K., Ye, S.H., Kim, S., Wagner, W.R., Hazen, N., & Chun, Y. (2023). In vitro and in vivo assessment of a novel ultra-flexible ventriculoamniotic shunt for treating fetal hydrocephalus. J Biomater Appl, 37(8), 1423-1435.SAGE Publications. doi: 10.1177/08853282221125309.

Ibrahim, M., Nghiem, K.X.X., Chung, K., Elsisy, M., Gosai, U.J.J., Kim, S., Ye, S., Wagner, W.R.R., & Chun, Y. (2023). A Novel Low-Profile Self-Expanding Biodegradable Percutaneous Heart Valve Frame That Grows with a Child. COATINGS, 13(1), 184.MDPI. doi: 10.3390/coatings13010184.

Richards, E., Ye, S.H., Ash, S.R., & Li, L. (2023). A Perfluorocarbon-Coated ZrP Cation Exchanger with Excellent Ammonium Selectivity and Chemical Stability: An Oral Sorbent for End-Stage Kidney Disease (ESKD). Langmuir, 39(22), 7912-7921.American Chemical Society (ACS). doi: 10.1021/acs.langmuir.3c00753.

Herbert, R., Elsisy, M., Rigo, B., Lim, H.R., Kim, H., Choi, C., Kim, S., Ye, S.H., Wagner, W.R., Chun, Y., & Yeo, W.H. (2022). Fully implantable batteryless soft platforms with printed nanomaterial-based arterial stiffness sensors for wireless continuous monitoring of restenosis in real time. Nano Today, 46, 101557.Elsevier. doi: 10.1016/j.nantod.2022.101557.

Kim, S., Nowicki, K.W., Ye, S., Jang, K., Elsisy, M., Ibrahim, M., Chun, Y., Gross, B.A., Friedlander, R.M., & Wagner, W.R. (2022). Bioabsorbable, elastomer-coated magnesium alloy coils for treating saccular cerebrovascular aneurysms. Biomaterials, 290, 121857.Elsevier. doi: 10.1016/j.biomaterials.2022.121857.

Mercader, A., Ye, S.H., Kim, S., Orizondo, R.A., Cho, S.K., & Wagner, W.R. (2022). PDMS-Zwitterionic Hybrid for Facile, Antifouling Microfluidic Device Fabrication. Langmuir, 38(12), 3775-3784.American Chemical Society (ACS). doi: 10.1021/acs.langmuir.1c03375.

Richards, E., Ye, S.H., Ash, S.R., & Li, L. (2022). Developing a Selective Zirconium Phosphate Cation Exchanger to Adsorb Ammonium: Effect of a Gas-Permeable and Hydrophobic Coating. Langmuir, 38(28), 8677-8685.American Chemical Society (ACS). doi: 10.1021/acs.langmuir.2c01194.

Orizondo, R.A., Omecinski, K.S., May, A.G., Dhamotharan, V., Frankowski, B.J., Burgreen, G.W., Ye, S.H., Kocyildirim, E., Sanchez, P.G., D'Cunha, J., Wagner, W.R., & Federspiel, W.J. (2021). Month-long Respiratory Support by a Wearable Pumping Artificial Lung in an Ovine Model. Transplantation, 105(5), 999-1007.Wolters Kluwer. doi: 10.1097/TP.0000000000003481.

Chen, Y., Ye, S.H., Zhu, Y., Gu, X., Higuchi, S., Wan, G., & Wagner, W.R. (2020). Covalently-Attached, Surface-Eroding Polymer Coatings on Magnesium Alloys for Corrosion Control and Temporally Varying Support of Cell Adhesion. ADVANCED MATERIALS INTERFACES, 7(15).Wiley. doi: 10.1002/admi.202000356.

Kim, S., Ye, S.H., Adamo, A., Orizondo, R.A., Jo, J., Cho, S.K., & Wagner, W.R. (2020). A biostable, anti-fouling zwitterionic polyurethane-urea based on PDMS for use in blood-contacting medical devices. J Mater Chem B, 8(36), 8305-8314.Royal Society of Chemistry (RSC). doi: 10.1039/d0tb01220c.

May, A.G., Orizondo, R.A., Frankowski, B.J., Ye, S.H., Kocyildirim, E., Wagner, W.R., D'Cunha, J., & Federspiel, W.J. (2020). In vivo testing of the low-flow CO2 removal application of a compact, platform respiratory device. Intensive Care Med Exp, 8(1), 45.Springer Nature. doi: 10.1186/s40635-020-00329-9.

D'Amore, A., Luketich, S.K., Hoff, R., Ye, S.H., & Wagner, W.R. (2019). Blending Polymer Labile Elements at Differing Scales to Affect Degradation Profiles in Heart Valve Scaffolds. Biomacromolecules, 20(7), 2494-2505.American Chemical Society (ACS). doi: 10.1021/acs.biomac.9b00189.

Madhani, S.P., Frankowski, B.J., Ye, S.H., Burgreen, G.W., Wagner, W.R., Kormos, R., D'Cunha, J., & Federspiel, W.J. (2019). In Vivo 5 Day Animal Studies of a Compact, Wearable Pumping Artificial Lung. ASAIO J, 65(1), 94-100.Wolters Kluwer. doi: 10.1097/MAT.0000000000000740.

Pocivavsek, L., Ye, S.H., Pugar, J., Tzeng, E., Cerda, E., Velankar, S., & Wagner, W.R. (2019). Active wrinkles to drive self-cleaning: A strategy for anti-thrombotic surfaces for vascular grafts. Biomaterials, 192, 226-234.Elsevier. doi: 10.1016/j.biomaterials.2018.11.005.

Ye, S.H., Chen, Y., Mao, Z., Gu, X., Shankarraman, V., Hong, Y., Shanov, V., & Wagner, W.R. (2019). Biodegradable Zwitterionic Polymer Coatings for Magnesium Alloy Stents. Langmuir, 35(5), 1421-1429.American Chemical Society (ACS). doi: 10.1021/acs.langmuir.8b01623.

Chen, Y., Ye, S.H., Sato, H., Zhu, Y., Shanov, V., Tiasha, T., D'Amore, A., Luketich, S., Wan, G., & Wagner, W.R. (2018). Hybrid scaffolds of Mg alloy mesh reinforced polymer/extracellular matrix composite for critical-sized calvarial defect reconstruction. J Tissue Eng Regen Med, 12(6), 1374-1388.Wiley. doi: 10.1002/term.2668.

Howe, C., Mishra, S., Kim, Y.S., Chen, Y., Ye, S.H., Wagner, W.R., Jeong, J.W., Byun, H.S., Kim, J.H., Chun, Y., & Yeo, W.H. (2018). Stretchable, Implantable, Nanostructured Flow-Diverter System for Quantification of Intra-aneurysmal Hemodynamics. ACS Nano, 12(8), 8706-8716.American Chemical Society (ACS). doi: 10.1021/acsnano.8b04689.

Liu, L., Ye, S.H., Gu, X., Russell, T., Xu, Z., Sankar, J., Wagner, W.R., Lee, Y.C., & Yun, Y. (2018). Comparison of endothelial cell attachment on surfaces of biodegradable polymer-coated magnesium alloys in a microfluidic environment. In Deli, M.A. (Ed.). PLoS One, 13(10), e0205611.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0205611.

Malkin, A.D., Ye, S.H., Lee, E.J., Yang, X., Zhu, Y., Gamble, L.J., Federspiel, W.J., & Wagner, W.R. (2018). Development of zwitterionic sulfobetaine block copolymer conjugation strategies for reduced platelet deposition in respiratory assist devices. J Biomed Mater Res B Appl Biomater, 106(7), 2681-2692.Wiley. doi: 10.1002/jbm.b.34085.

Pocivavsek, L., Ye, S.H., Wagner, W., Tzeng, E., Pugar, J., O'Dea, R., Velankar, S., & Cerda, E. (2018). Topography Driven Surface Renewal. Nat Phys, 14(9), 948-953.Springer Nature. doi: 10.1038/s41567-018-0193-x.

Fang, J., Zhang, J., Du, J., Pan, Y., Shi, J., Peng, Y., Chen, W., Yuan, L., Ye, S.H., Wagner, W.R., Yin, M., & Mo, X. (2016). Orthogonally Functionalizable Polyurethane with Subsequent Modification with Heparin and Endothelium-Inducing Peptide Aiming for Vascular Reconstruction. ACS Appl Mater Interfaces, 8(23), 14442-14452.American Chemical Society (ACS). doi: 10.1021/acsami.6b04289.

Gu, X., Mao, Z., Ye, S.H., Koo, Y., Yun, Y., Tiasha, T.R., Shanov, V., & Wagner, W.R. (2016). Biodegradable, elastomeric coatings with controlled anti-proliferative agent release for magnesium-based cardiovascular stents. Colloids Surf B Biointerfaces, 144, 170-179.Elsevier. doi: 10.1016/j.colsurfb.2016.03.086.

Fang, J., Ye, S.H., Wang, J., Zhao, T., Mo, X., & Wagner, W.R. (2015). Thiol click modification of cyclic disulfide containing biodegradable polyurethane urea elastomers. Biomacromolecules, 16(5), 1622-1633.American Chemical Society (ACS). doi: 10.1021/acs.biomac.5b00192.

Ye, S.H., Arazawa, D.T., Zhu, Y., Shankarraman, V., Malkin, A.D., Kimmel, J.D., Gamble, L.J., Ishihara, K., Federspiel, W.J., & Wagner, W.R. (2015). Hollow fiber membrane modification with functional zwitterionic macromolecules for improved thromboresistance in artificial lungs. Langmuir, 31(8), 2463-2471.American Chemical Society (ACS). doi: 10.1021/la504907m.

Zhu, Y., Jiang, H., Ye, S.H., Yoshizumi, T., & Wagner, W.R. (2015). Tailoring the degradation rates of thermally responsive hydrogels designed for soft tissue injection by varying the autocatalytic potential. Biomaterials, 53, 484-493.Elsevier. doi: 10.1016/j.biomaterials.2015.02.100.

Fang, J., Ye, S.H., Shankarraman, V., Huang, Y., Mo, X., & Wagner, W.R. (2014). Biodegradable poly(ester urethane)urea elastomers with variable amino content for subsequent functionalization with phosphorylcholine. Acta Biomater, 10(11), 4639-4649.Elsevier. doi: 10.1016/j.actbio.2014.08.008.

Park, D.W., Ye, S.H., Jiang, H.B., Dutta, D., Nonaka, K., Wagner, W.R., & Kim, K. (2014). In vivo monitoring of structural and mechanical changes of tissue scaffolds by multi-modality imaging. Biomaterials, 35(27), 7851-7859.Elsevier. doi: 10.1016/j.biomaterials.2014.05.088.

Perkins, J., Hong, Y., Ye, S.H., Wagner, W.R., & Desai, S. (2014). Direct writing of bio-functional coatings for cardiovascular applications. J Biomed Mater Res A, 102(12), 4290-4300.Wiley. doi: 10.1002/jbm.a.35105.

Ye, S.H., Hong, Y., Sakaguchi, H., Shankarraman, V., Luketich, S.K., D'Amore, A., & Wagner, W.R. (2014). Nonthrombogenic, biodegradable elastomeric polyurethanes with variable sulfobetaine content. ACS Appl Mater Interfaces, 6(24), 22796-22806.American Chemical Society (ACS). doi: 10.1021/am506998s.

Kimmel, J.D., Arazawa, D.T., Ye, S.H., Shankarraman, V., Wagner, W.R., & Federspiel, W.J. (2013). Carbonic anhydrase immobilized on hollow fiber membranes using glutaraldehyde activated chitosan for artificial lung applications. J Mater Sci Mater Med, 24(11), 2611-2621.Springer Nature. doi: 10.1007/s10856-013-5006-2.

Ye, S.H., Jang, Y.S., Yun, Y.H., Shankarraman, V., Woolley, J.R., Hong, Y., Gamble, L.J., Ishihara, K., & Wagner, W.R. (2013). Surface modification of a biodegradable magnesium alloy with phosphorylcholine (PC) and sulfobetaine (SB) functional macromolecules for reduced thrombogenicity and acute corrosion resistance. Langmuir, 29(26), 8320-8327.American Chemical Society (ACS). doi: 10.1021/la401341y.

Arazawa, D.T., Oh, H.I., Ye, S.H., Johnson, C.A., Woolley, J.R., Wagner, W.R., & Federspiel, W.J. (2012). Immobilized Carbonic Anhydrase on Hollow Fiber Membranes Accelerates CO(2) Removal from Blood. J Memb Sci, 404-404, 25-31.Elsevier. doi: 10.1016/j.memsci.2012.02.006.

Hong, Y., Ye, S.H., Pelinescu, A.L., & Wagner, W.R. (2012). Synthesis, characterization, and paclitaxel release from a biodegradable, elastomeric, poly(ester urethane)urea bearing phosphorylcholine groups for reduced thrombogenicity. Biomacromolecules, 13(11), 3686-3694.American Chemical Society (ACS). doi: 10.1021/bm301158j.

Aumsuwan, N., Ye, S.H., Wagner, W.R., & Urban, M.W. (2011). Covalent attachment of multilayers on poly(tetrafluoroethylene) surfaces. Langmuir, 27(17), 11106-11110.American Chemical Society (ACS). doi: 10.1021/la201957a.

Johnson, C.A., Vandenberghe, S., Daly, A.R., Woolley, J.R., Snyder, S.T., Verkaik, J.E., Ye, S.H., Borovetz, H.S., Antaki, J.F., Wearden, P.D., Kameneva, M.V., & Wagner, W.R. (2011). Biocompatibility assessment of the first generation PediaFlow pediatric ventricular assist device. Artif Organs, 35(1), 9-21.Wiley. doi: 10.1111/j.1525-1594.2010.01023.x.

Johnson, C.A., Wearden, P.D., Kocyildirim, E., Maul, T.M., Woolley, J.R., Ye, S.H., Strickler, E.M., Borovetz, H.S., & Wagner, W.R. (2011). Platelet activation in ovines undergoing sham surgery or implant of the second generation PediaFlow pediatric ventricular assist device. Artif Organs, 35(6), 602-613.Wiley. doi: 10.1111/j.1525-1594.2010.01124.x.

Soletti, L., Nieponice, A., Hong, Y., Ye, S.H., Stankus, J.J., Wagner, W.R., & Vorp, D.A. (2011). In vivo performance of a phospholipid-coated bioerodable elastomeric graft for small-diameter vascular applications. J Biomed Mater Res A, 96(2), 436-448.Wiley. doi: 10.1002/jbm.a.32997.

Oh, H.I., Ye, S.H., Johnson, C.A., Woolley, J.R., Federspiel, W.J., & Wagner, W.R. (2010). Hemocompatibility assessment of carbonic anhydrase modified hollow fiber membranes for artificial lungs. Artif Organs, 34(5), 439-442.Wiley. doi: 10.1111/j.1525-1594.2009.00882.x.

Ye, S.H., Johnson, C.A., Woolley, J.R., Murata, H., Gamble, L.J., Ishihara, K., & Wagner, W.R. (2010). Simple surface modification of a titanium alloy with silanated zwitterionic phosphorylcholine or sulfobetaine modifiers to reduce thrombogenicity. Colloids Surf B Biointerfaces, 79(2), 357-364.Elsevier. doi: 10.1016/j.colsurfb.2010.04.018.

Hong, Y., Ye, S.H., Nieponice, A., Soletti, L., Vorp, D.A., & Wagner, W.R. (2009). A small diameter, fibrous vascular conduit generated from a poly(ester urethane)urea and phospholipid polymer blend. Biomaterials, 30(13), 2457-2467.Elsevier. doi: 10.1016/j.biomaterials.2009.01.013.

Ye, S.H., Johnson, C.A., Woolley, J.R., Oh, H.I., Gamble, L.J., Ishihara, K., & Wagner, W.R. (2009). Surface modification of a titanium alloy with a phospholipid polymer prepared by a plasma-induced grafting technique to improve surface thromboresistance. Colloids Surf B Biointerfaces, 74(1), 96-102.Elsevier. doi: 10.1016/j.colsurfb.2009.06.032.

Ye, S.H., Johnson, C.A., Woolley, J.R., Snyder, T.A., Gamble, L.J., & Wagner, W.R. (2009). Covalent surface modification of a titanium alloy with a phosphorylcholine-containing copolymer for reduced thrombogenicity in cardiovascular devices. J Biomed Mater Res A, 91(1), 18-28.Wiley. doi: 10.1002/jbm.a.32184.

Ho Ye, S., Watanabe, J., Takai, M., Iwasaki, Y., & Ishihara, K. (2006). High functional hollow fiber membrane modified with phospholipid polymers for a liver assist bioreactor. Biomaterials, 27(9), 1955-1962.Elsevier. doi: 10.1016/j.biomaterials.2005.09.041.

Ye, S.H., Watanabe, J., Iwasaki, Y., & Ishihara, K. (2005). In situ modification on cellulose acetate hollow fiber membrane modified with phospholipid polymer for biomedical application. JOURNAL OF MEMBRANE SCIENCE, 249(1-2), 133-141.Elsevier. doi: 10.1016/j.memsci.2004.10.006.

Ye, S.H., Watanabe, J., Takai, M., Iwasaki, Y., & Ishihara, K. (2005). Design of functional hollow fiber membranes modified with phospholipid polymers for application in total hemopurification system. Biomaterials, 26(24), 5032-5041.Elsevier. doi: 10.1016/j.biomaterials.2005.01.049.

Ye, S.H., Watanabe, J., & Ishihara, K. (2004). Cellulose acetate hollow fiber membranes blended with phospholipid polymer and their performance for hemopurification. J Biomater Sci Polym Ed, 15(8), 981-1001.Taylor & Francis. doi: 10.1163/1568562041526450.

Ye, S.H., Watanabe, J., Iwasaki, Y., & Ishihara, K. (2003). Antifouling blood purification membrane composed of cellulose acetate and phospholipid polymer. Biomaterials, 24(23), 4143-4152.Elsevier. doi: 10.1016/s0142-9612(03)00296-5.

Ye, S.H., Watanabe, J., Iwasaki, Y., & Ishihara, K. (2002). Novel cellulose acetate membrane blended with phospholipid polymer for hemocompatible filtration system. JOURNAL OF MEMBRANE SCIENCE, 210(2), 411-421.Elsevier. doi: 10.1016/S0376-7388(02)00421-0.

Orizondo, R.A., May, A., Frankowski, B.J., Burgreen, G., Ye, S., Kocyildirim, E., Wagner, W., D’Cunha, J., Kormos, R., & Federspiel, W. (2019). Pittsburgh Paracorporeal Ambulatory Assist Lung: Progress Towards a Long-Term Wearable Artificial Lung. American Society of Artificial Internal Organs (ASAIO) 65th Annual Conference.San Francisco.

Orizondo, R., Madhani, S., May, A., Frankowski, B.J., Ye, S., Kocyildirim, E., Wagner, W., Kormos, R., D’Cunha, J., & Federspiel, W. (2018). Successful 30-day Sheep Studies of a Wearable Pumping Artificial Lung. Poster session presented at the meeting of McGowan Institute Scientific Retreat.Pittsburgh, PA.

Orizondo, R.A., Madhani, S.P., May, A., Frankowski, B.J., Burgreen, G.W., Ye, S., Kocyildirim, E., Wagner, W., Kormos, R.L., D'Cunha, J., & Federspiel, W. (2018). 30 Day Sheep Studies of a Wearable Pumping Artificial Lung. 64th Annual American Society for Artificial Internal Organs (ASAIO) Conference.Washington, DC.

Richards, E., Federspiel, W., Liu, X., Sharma, A.C., Ghosh, R., & Ye, S. (2018). Advancing a System for Generating Universal Blood Plasma. Poster session presented at the meeting of McGowan Institute Scientific Retreat.Pittsburgh, PA.

Valencia-Rivero, K.T., Cruz, J.C., Briceño, J.C., D’Amore, A., Ye, S.H., Geest, J.V., & Wagner, W.R. (2018). Decreased Platelet Deposition in SIS-Based Vascular Grafts via Covalent Conjugation of RAFT Polymers. In 2018 IX International Seminar of Biomedical Engineering (SIB), 00, (pp. 1-6).Institute of Electrical and Electronics Engineers (IEEE). doi: 10.1109/sib.2018.8467727.

Wearden, P.D., Snyder, T.A., Stanfield, J.R., Coghill, P., Crompton, D., Olia, S.E., Ye, S., Kameneva, M.V., Wagner, W.R., & Long, J.W. (2017). Development of Miniature, Implantable Pediatric Ventricular Assist Device. In JOURNAL OF HEART AND LUNG TRANSPLANTATION, 36(4), (p. S163).

Gu, X., Mao, Z., Ye, S.H., Koo, Y., Yun, Y., Shanov, V., & Wagner, W. (2016). Biodegradable polyurethane elastomers as coatings for magnesium-based cardiovascular stents. In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 252.

Washington, C.B., Ye, S.H., Sakaguchi, H., Shukla, A.J., Wagner, W.R., & Tzeng, E. (2014). Electrospun Poly(ester urethane) Urea Dressings Improve Wound Healing in Diabetic Mice. In JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 219(3), (pp. S160-S161).Wolters Kluwer. doi: 10.1016/j.jamcollsurg.2014.07.385.

Nieponice, A., Soletti, L., Hong, Y., Ye, S.H., Stankus, J., Guan, J., Wagner, W.R., & Vorp, D.A. (2008). A surface-modified electrospun elastomeric scaffold as a small diameter vascular graft in a rat model. Poster session presented at the meeting of TERMIS Conference and Exhibition.Porto, Portugal.

Ye, S.H., Woolley, J.R., Johnson, C.A., & Wagner, W.R. (2008). Surface modification of a titanium alloy with a sulfonated silane modifier to improve blood compatibility. In 8th World Biomaterials Congress 2008, 4, (p. 2274).

Ye, S.H., & Kikuchi, M. (2007). Development of a Bioactive Inorganic/Organic Composite for Bone Formation Active Drug Carrier. In Key Engineering Materials, 330-332 II, (pp. 1049-1052).Trans Tech Publications Ltd. doi: 10.4028/0-87849-422-7.1049.

Ye, S.H., Watanabe, J., & Ishihara, K. (2004). Cellulose acetate hollow fiber membranes modified by phospholipid polymers for hemopurification. In Transactions - 7th World Biomaterials Congress, (p. 1701).

Federspiel, W., Frankowski, B., Antaki, J., Bermudez, C., Jeffries, R., Wagner, W., & Ye, S. (2018). Extracorporeal ambulatory assist lung. 10,080,834.