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Elena Goncharova

Associate Professor
Bioengineering Department

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Bhagwani, A.R., Farkas, D., Harmon, B., Authelet, K.J., Cool, C.D., Kolb, M., Goncharova, E., Yoder, M.C., Clauss, M., Freishtat, R., & Farkas, L. (2020). Clonally selected primitive endothelial cells promote occlusive pulmonary arteriopathy and severe pulmonary hypertension in rats exposed to chronic hypoxia. Sci Rep, 10(1), 1136.Springer Science and Business Media LLC. doi: 10.1038/s41598-020-58083-7.

Goncharova, E.A., Chan, S.Y., Ventetuolo, C.E., Weissmann, N., Schermuly, R.T., Mullin, C.J., & Gladwin, M.T. (2020). Update in Pulmonary Vascular Diseases and Right Ventricular Dysfunction 2019. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 202(1), 22-28.American Thoracic Society. doi: 10.1164/rccm.202003-0576UP.

Goncharova, E.A., Simon, M.A., & Yuan, J.X.J. (2020). mTORC1 in Pulmonary Arterial Hypertension At the Crossroads between Vasoconstriction and Vascular Remodeling?. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 201(10), 1177-1179.American Thoracic Society. doi: 10.1164/rccm.202001-0087ED.

Shen, Y., Goncharov, D.A., Avolio, T., Ray, A., Okorie, E., DeLisser, H., Mora, A.L., Vanderpool, R., Kudryashova, T.V., & Goncharova, E.A. (2020). Differential effects of integrin-linked kinase inhibitor Cpd22 on severe pulmonary hypertension in male and female rats. PULMONARY CIRCULATION, 10(1), 2045894019898593.SAGE Publications. doi: 10.1177/2045894019898593.

Estephan, L.E., Genuardi, M.V., Kosanovich, C.M., Risbano, M.G., Zhang, Y., Petro, N., Watson, A., Al Aaraj, Y., Sembrat, J.C., Rojas, M., Goncharov, D.A., Simon, M.A., Goncharova, E.A., Vaidya, A., Smith, A., Mazurek, J., Han, Y., & Chan, S.Y. (2019). Distinct plasma gradients of microRNA-204 in the pulmonary circulation of patients suffering from WHO Groups I and II pulmonary hypertension. PULMONARY CIRCULATION, 9(2), 2045894019840646.SAGE Publications. doi: 10.1177/2045894019840646.

Farkas, D., Thompson, A.A.R., Bhagwani, A.R., Hultman, S., Ji, H., Kotha, N., Farr, G., Arnold, N.D., Braithwaite, A., Casbolt, H., Cole, J.E., Sabroe, I., Monaco, C., Cool, C.D., Goncharova, E.A., Lawrie, A., & Farkas, L. (2019). Toll-like Receptor 3 Is a Therapeutic Target for Pulmonary Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 199(2), 199-210.American Thoracic Society. doi: 10.1164/rccm.201707-1370OC.

Lai, Y.C., Provencher, S., & Goncharova, E.A. (2019). TAKling GDF-15 and skeletal muscle atrophy in pulmonary hypertension: are we there yet?. THORAX, 74(2), 103-105.BMJ. doi: 10.1136/thoraxjnl-2018-212680.

Spiekerkoetter, E., Goncharova, E.A., Guignabert, C., Stenmark, K., Kwapiszewska, G., Rabinovitch, M., Voelkel, N., Bogaard, H.J., Graham, B., Pullamsetti, S.S., & Kuebler, W.M. (2019). Hot topics in the mechanisms of pulmonary arterial hypertension disease: cancer-like pathobiology, the role of the adventitia, systemic involvement, and right ventricular failure. PULMONARY CIRCULATION, 9(4), 2045894019889775.SAGE Publications. doi: 10.1177/2045894019889775.

Goncharov, D.A., Goncharova, E.A., Tofovic, S.P., Hu, J., Baust, J.J., Pena, A.Z., Ray, A., Rode, A., Vanderpool, R.R., Mora, A.L., Gladwin, M.T., & Lai, Y.C. (2018). Metformin Therapy for Pulmonary Hypertension Associated with Heart Failure with Preserved Ejection Fraction versus Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 198(5), 681-684.American Thoracic Society. doi: 10.1164/rccm.201801-0022LE.

Kudryashova, T.V., Shen, Y., Pena, A., Cronin, E., Okorie, E., Goncharov, D.A., & Goncharova, E.A. (2018). Inhibitory Antibodies against Activin A and TGF-beta Reduce Self-Supported, but Not Soluble Factors-Induced Growth of Human Pulmonary Arterial Vascular Smooth Muscle Cells in Pulmonary Arterial Hypertension. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 19(10), 2957.MDPI AG. doi: 10.3390/ijms19102957.

Shen, Y.S., & Goncharova, E.A. (2018). TWISTed HIF: revisiting smooth muscle HIF-1 alpha signaling in pulmonary hypertension. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 315(3), L387-L389.American Physiological Society. doi: 10.1152/ajplung.00285.2018.

Al Ghouleh, I., Sahoo, S., Meijles, D.N., Amaral, J.H., de Jesus, D.S., Sembrat, J., Rojas, M., Goncharov, D.A., Goncharova, E.A., & Pagano, P.J. (2017). Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation. CLINICAL SCIENCE, 131(15), 2019-2035.Portland Press Ltd. doi: 10.1042/CS20160812.

Alvarez, R.A., Miller, M.P., Hahn, S.A., Galley, J.C., Bauer, E., Bachman, T., Hu, J., Sembrat, J., Goncharov, D., Mora, A.L., Rojas, M., Goncharova, E., & Straub, A.C. (2017). Targeting Pulmonary Endothelial Hemoglobin a Improves Nitric Oxide Signaling and Reverses Pulmonary Artery Endothelial Dysfunction. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 57(6), 733-744.American Thoracic Society. doi: 10.1165/rcmb.2016-0418OC.

Boucherat, O., Chabot, S., Paulin, R., Trinh, I., Bourgeois, A., Potus, F., Lampron, M.C., Lambert, C., Breuils-Bonnet, S., Nadeau, V., Paradis, R., Goncharova, E.A., Provencher, S., & Bonnet, S. (2017). HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension. SCIENTIFIC REPORTS, 7(1), 4546.Springer Science and Business Media LLC. doi: 10.1038/s41598-017-04874-4.

Falabella, M., Sun, L., Barr, J., Pena, A.Z., Kershaw, E.E., Gingras, S., Goncharova, E.A., & Kaufman, B.A. (2017). Single-Step qPCR and dPCR Detection of Diverse CRISPR-Cas9 Gene Editing Events In Vivo. G3-GENES GENOMES GENETICS, 7(10), 3533-3542.Oxford University Press (OUP). doi: 10.1534/g3.117.300123.

Meng, Q., Lai, Y.C., Kelly, N.J., Bueno, M., Baust, J.J., Bachman, T.N., Goncharov, D., Vanderpool, R.R., Radder, J.E., Hu, J., Goncharova, E., Morris, A.M., Mora, A.L., Shapiro, S.D., & Gladwin, M.T. (2017). Development of a Mouse Model of Metabolic Syndrome, Pulmonary Hypertension, and Heart Failure with Preserved Ejection Fraction. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 56(4), 497-505.American Thoracic Society. doi: 10.1165/rcmb.2016-0177OC.

Pena, A., Kobir, A., Goncharov, D., Goda, A., Kudryashova, T.V., Ray, A., Vanderpool, R., Baust, J., Chang, B., Mora, A.L., III, G.J., & Goncharova, E.A. (2017). Pharmacological Inhibition of mTOR Kinase Reverses Right Ventricle Remodeling and Improves Right Ventricle Structure and Function in Rats. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 57(5), 615-625.American Thoracic Society. doi: 10.1165/rcmb.2016-0364OC.

Pullamsettit, S.S., Savai, R., Seeger, W., & Goncharova, E.A. (2017). From Cancer Biology to New Pulmonary Arterial Hypertension Therapeutics Targeting Cell Growth and Proliferation Signaling Hubs. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 195(4), 425-437.American Thoracic Society. doi: 10.1164/rccm.201606-1226PP.

Kelly, N.J., Dandachi, N., Goncharov, D.A., Pena, A.Z., Radder, J.E., Gregory, A.D., Lai, Y.C., Leme, A.S., Gladwin, M.T., Goncharova, E.A., St Croix, C.M., & Shapiro, S.D. (2016). Automated Measurement of Blood Vessels in Tissues from Microscopy Images. Curr Protoc Cytom, 78(1), 12.44.1-12.44.13.Wiley. doi: 10.1002/cpcy.10.

Kudryashova, T.V., Goncharov, D.A., Pena, A., Kelly, N., Vanderpool, R., Baust, J., Kobir, A., Shufesky, W., Mora, A.L., Morelli, A.E., Zhao, J., Ihida-Stansbury, K., Chang, B., DeLisser, H., Tuder, R.M., Kawut, S.M., Sillje, H.H.W., Shapiro, S., Zhao, Y., & Goncharova, E.A. (2016). HIPPO-Integrin-linked Kinase Cross-Talk Controls Self-Sustaining Proliferation and Survival in Pulmonary Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 194(7), 866-877.American Thoracic Society. doi: 10.1164/rccm.201510-2003OC.

Lai, Y.C., Tabima, D.M., Dube, J.J., Hughan, K.S., Vanderpool, R.R., Goncharov, D.A., St Croix, C.M., Garcia-Ocana, A., Goncharova, E.A., Tofovic, S.P., Mora, A.L., & Gladwin, M.T. (2016). SIRT3-AMP-Activated Protein Kinase Activation by Nitrite and Metformin Improves Hyperglycemia and Normalizes Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction. CIRCULATION, 133(8), 717-731.Ovid Technologies (Wolters Kluwer Health). doi: 10.1161/CIRCULATIONAHA.115.018935.

Romero, Y., Bueno, M., Ramirez, R., Alvarez, D., Sembrat, J.C., Goncharova, E.A., Rojas, M., Selman, M., Mora, A.L., & Pardo, A. (2016). mTORC1 activation decreases autophagy in aging and idiopathic pulmonary fibrosis and contributes to apoptosis resistance in IPF fibroblasts. AGING CELL, 15(6), 1103-1112.Wiley. doi: 10.1111/acel.12514.

Sahoo, S., Meijles, D.N., Al Ghouleh, I., Tandon, M., Cifuentes-Pagano, E., Sembrat, J., Rojas, M., Goncharova, E., & Pagano, P.J. (2016). MEF2C-MYOCD and Leiomodin1 Suppression by miRNA-214 Promotes Smooth Muscle Cell Phenotype Switching in Pulmonary Arterial Hypertension. In Xiao, Q. (Ed.). PLOS ONE, 11(5), e0153780.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0153780.

Agassandian, M., Tedrow, J.R., Sembrat, J., Kass, D.J., Zhang, Y., Goncharova, E.A., Kaminski, N., Mallampalli, R.K., & Vuga, L.J. (2015). VCAM-1 is a TGF-beta 1 inducible gene upregulated in idiopathic pulmonary fibrosis. CELLULAR SIGNALLING, 27(12), 2467-2473.Elsevier BV. doi: 10.1016/j.cellsig.2015.09.003.

Goncharova, E.A., Gladwin, M.T., & Kawut, S.M. (2015). Update in Pulmonary Vascular Diseases 2014. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 192(5), 544-550.American Thoracic Society. doi: 10.1164/rccm.201504-0829UP.

Goncharova, E.A., James, M.L., Kudryashova, T.V., Goncharov, D.A., & Krymskaya, V.P. (2015). Tumor Suppressors TSC1 and TSC2 Differentially Modulate Actin Cytoskeleton and Motility of Mouse Embryonic Fibroblasts (vol 9, e111476, 2014). PLOS ONE, 10(3), e0118637.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0118637.

Kudryashova, T.V., Goncharov, D.A., Pena, A., Ihida-Stansbury, K., DeLisser, H., Kawut, S.M., & Goncharova, E.A. (2015). Profiling the role of mammalian target of rapamycin in the vascular smooth muscle metabolome in pulmonary arterial hypertension. PULMONARY CIRCULATION, 5(4), 667-680.SAGE Publications. doi: 10.1086/683810.

Goncharov, D.A., Kudryashova, T.V., Ziai, H., Ihida-Stansbury, K., DeLisser, H., Krymskaya, V.P., Tuder, R.M., Kawut, S.M., & Goncharova, E.A. (2014). Mammalian Target of Rapamycin Complex 2 ( mTORC2) Coordinates Pulmonary Artery Smooth Muscle Cell Metabolism, Proliferation, and Survival in Pulmonary Arterial Hypertension. CIRCULATION, 129(8), 864-874.Ovid Technologies (Wolters Kluwer Health). doi: 10.1161/CIRCULATIONAHA.113.004581.

Goncharova, E.A., Goncharov, D.A., James, M.L., Atochina-Vasserman, E.N., Stepanova, V., Hong, S.B., Li, H., Gonzales, L., Baba, M., Linehan, W.M., Gow, A.J., Margulies, S., Guttentag, S., Schmidt, L.S., & Krymskaya, V.P. (2014). Folliculin Controls Lung Alveolar Enlargement and Epithelial Cell Survival through E-Cadherin, LKB1, and AMPK. CELL REPORTS, 7(2), 412-423.Elsevier BV. doi: 10.1016/j.celrep.2014.03.025.

Goncharova, E.A., James, M.L., Kudryashova, T.V., Goncharov, D.A., & Krymskaya, V.P. (2014). Tumor Suppressors TSC1 and TSC2 Differentially Modulate Actin Cytoskeleton and Motility of Mouse Embryonic Fibroblasts. PLOS ONE, 9(10), e111476.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0111476.

Goncharova, E.A. (2013). mTOR and vascular remodeling in lung diseases: current challenges and therapeutic prospects. FASEB JOURNAL, 27(5), 1796-1807.Wiley. doi: 10.1096/fj.12-222224.

Goncharova, E.A., Goncharov, D.A., Fehrenbach, M., Khavin, I., Ducka, B., Hino, O., Colby, T.V., Merrilees, M.J., Haczku, A., Albelda, S.M., & Krymskaya, V.P. (2012). Prevention of Alveolar Destruction and Airspace Enlargement in a Mouse Model of Pulmonary Lymphangioleiomyomatosis ( LAM). SCIENCE TRANSLATIONAL MEDICINE, 4(154), 154ra134.American Association for the Advancement of Science (AAAS). doi: 10.1126/scitranslmed.3003840.

Goncharova, E.A., Goncharov, D.A., Zhao, H., Penn, R.B., Krymskaya, V.P., & Jr, P.R.A. (2012). beta(2)-Adrenergic Receptor Agonists Modulate Human Airway Smooth Muscle Cell Migration via Vasodilator-Stimulated Phosphoprotein. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 46(1), 48-54.American Thoracic Society. doi: 10.1165/rcmb.2011-0217OC.

Goncharova, E.A., Khavin, I.S., Goncharov, D.A., & Krymskaya, V.P. (2012). Differential effects of formoterol on thrombin- and PDGF-induced proliferation of human pulmonary arterial vascular smooth muscle cells. RESPIRATORY RESEARCH, 13(1), 109.Springer Science and Business Media LLC. doi: 10.1186/1465-9921-13-109.

Koziol-White, C.J., Goncharova, E.A., Cao, G., Johnson, M., Krymskaya, V.P., & Jr, P.R.A. (2012). DHEA-S inhibits human neutrophil and human airway smooth muscle migration. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1822(10), 1638-1642.Elsevier BV. doi: 10.1016/j.bbadis.2012.06.012.

Medvetz, D.A., Khabibullin, D., Hariharan, V., Ongusaha, P.P., Goncharova, E.A., Schlechter, T., Darling, T.N., Hofmann, I., Krymskaya, V.P., Liao, J.K., Huang, H., & Henske, E.P. (2012). Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion. PLOS ONE, 7(11), e47842.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0047842.

Goncharova, E.A., Goncharov, D.A., Li, H., Pimtong, W., Lu, S., Khavin, I., & Krymskaya, V.P. (2011). mTORC2 Is Required for Proliferation and Survival of TSC2-Null Cells. MOLECULAR AND CELLULAR BIOLOGY, 31(12), 2484-2498.American Society for Microbiology. doi: 10.1128/MCB.01061-10.

Krymskaya, V.P., Snow, J., Cesarone, G., Khavin, I., Goncharov, D.A., Lim, P.N., Veasey, S.C., Ihida-Stansbury, K., Jones, P.L., & Goncharova, E.A. (2011). mTOR is required for pulmonary arterial vascular smooth muscle cell proliferation under chronic hypoxia. FASEB JOURNAL, 25(6), 1922-1933.Wiley. doi: 10.1096/fj.10-175018.

Goncharova, E.A., Lim, P.N., Chisolm, A., III, F.H.W., Taylor, J.H., Goncharov, D.A., Eszterhas, A., Jr, P.R.A., & Krymskaya, V.P. (2010). Interferons modulate mitogen-induced protein synthesis in airway smooth muscle. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 299(1), L25-L35.American Physiological Society. doi: 10.1152/ajplung.00228.2009.

Damera, G., Fogle, H.W., Lim, P., Goncharova, E.A., Zhao, H., Banerjee, A., Tliba, O., Krymskaya, V.P., & Jr, P.R.A. (2009). Vitamin D inhibits growth of human airway smooth muscle cells through growth factor-induced phosphorylation of retinoblastoma protein and checkpoint kinase 1. BRITISH JOURNAL OF PHARMACOLOGY, 158(6), 1429-1441.Wiley. doi: 10.1111/j.1476-5381.2009.00428.x.

Goncharova, E.A., Goncharov, D.A., Damera, G., Tliba, O., Amrani, Y., Jr, P.R.A., & Krymskaya, V.P. (2009). Signal Transducer and Activator of Transcription 3 Is Required for Abnormal Proliferation and Survival of TSC2-Deficient Cells: Relevance to Pulmonary Lymphangioleiomyomatosis. MOLECULAR PHARMACOLOGY, 76(4), 766-777.American Society for Pharmacology & Experimental Therapeutics (ASPET). doi: 10.1124/mol.109.057042.

Krymskaya, V.P., & Goncharova, E.A. (2009). PI3K/mTORC1 activation in hamartoma syndromes Therapeutic prospects. CELL CYCLE, 8(3), 403-413.Informa UK Limited. doi: 10.4161/cc.8.3.7555.

Goncharova, E.A., & Krymskaya, V.P. (2008). Pulmonary lymphangioleiomyomatosis (LAM): Progress and current challenges. JOURNAL OF CELLULAR BIOCHEMISTRY, 103(2), 369-382.Wiley. doi: 10.1002/jcb.21419.

Goncharova, E.A., Goncharov, D.A., Chisolm, A., Spaits, M.S., Lim, P.N., Cesarone, G., Khavin, I., Tliba, O., Amrani, Y., Jr, P.R.A., & Krymskaya, V.P. (2008). Interferon beta augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation. MOLECULAR PHARMACOLOGY, 73(3), 778-788.American Society for Pharmacology & Experimental Therapeutics (ASPET). doi: 10.1124/mol.107.040824.

Goncharova, E.A., Goncharov, D.A., & Krymskaya, V.P. (2006). Assays for in vitro monitoring of human airway smooth muscle (ASM) and human pulmonary arterial vascular smooth muscle (VSM) cell migration. NATURE PROTOCOLS, 1(6), 2933-2939.Springer Science and Business Media LLC. doi: 10.1038/nprot.2006.434.

Goncharova, E.A., Goncharov, D.A., Lim, P.N., Noonan, D., & Krymskaya, V.P. (2006). Modulation of cell migration and invasiveness by tumor suppressor TSC2 in lymphangioleiomyomatosis. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 34(4), 473-480.American Thoracic Society. doi: 10.1165/rcmb.2005-0374OC.

Goncharova, E.A., Goncharov, D.A., Spaits, M., Noonan, D.J., Talovskaya, E., Eszterhas, A., & Krymskaya, V.P. (2006). Abnormal growth of smooth muscle-like cells in lymphangioleiomyomatosis - Role for tumor suppressor TSC2. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 34(5), 561-572.American Thoracic Society. doi: 10.1165/rcmb.2005-0300OC.

Goncharova, E.A., Lim, P., Goncharov, D.A., Eszterhas, A., Jr, P.R.A., & Krymskaya, V.P. (2006). Assays for in vitro monitoring of proliferation of human airway smooth muscle (ASM) and human pulmonary arterial vascular smooth muscle (VSM) cells. NATURE PROTOCOLS, 1(6), 2905-2908.Springer Science and Business Media LLC. doi: 10.1038/nprot.2006.433.

Goncharova, E., Goncharov, D., Noonan, D., & Krymskaya, V.P. (2004). TSC2 modulates actin cytoskeleton and focal adhesion through TSC1-binding domain and the Rac1 GTPase. J Cell Biol, 167(6), 1171-1182.Rockefeller University Press. doi: 10.1083/jcb.200405130.

Kazi, A.S., Lotfi, S., Goncharova, E.A., Tliba, O., Amrani, Y., Krymskaya, V.P., & Lazaar, A.L. (2004). Vascular endothelial growth factor-induced secretion of fibronectin is ERK dependent. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 286(3), L539-L545.American Physiological Society. doi: 10.1152/ajplung.00130.2003.

Kazi, A.S., Lotfi, S., Goncharova, E.A., Tliba, O., Amrani, Y., Krymskaya, V.P., & Lazaar, A.L. (2004). Vascular endothelial growth factor-induced secretion of fibronectin is ERK dependent. American Journal of Physiology - Lung Cellular and Molecular Physiology, 286(3 30-3). doi: 10.1152/ajplung.00130.2003.

Krymskaya, V.P., Goncharova, E.A., Ammit, A.J., Lim, P.N., Goncharov, D.A., Eszterhas, A., & Panettieri, R.A. (2004). Src is necessary and sufficient for human airway smooth muscle cell proliferation and migration. FASEB JOURNAL, 18(15), 428-+.Wiley. doi: 10.1096/fj.04-2869fje.

Goncharova, E.A., Billington, C.K., Irani, C., Vorotnikov, A.V., Tkachuk, V.A., Penn, R.B., Krymskaya, V.P., & Panettieri, R.A. (2003). Cyclic AMP-mobilizing agents and glucocorticoids modulate human smooth muscle cell migration. Am J Respir Cell Mol Biol, 29(1), 19-27.American Thoracic Society. doi: 10.1165/rcmb.2002-0254OC.

Goncharova, E.A., Billington, C.K., Irani, C., Vorotnikov, A.V., Tkachuk, V.A., Penn, R.B., Krymskaya, V.P., & Panettieri, R.A. (2003). Cyclic AMP-mobilizing agents and glucocorticoids modulate human smooth muscle cell migration. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 29(1), 19-27. doi: 10.1165/rcmb.2002-0254OC.

Goncharova, E.A., Ammit, A.J., Irani, C., Carroll, R.G., Eszterhas, A.J., Panettieri, R.A., & Krymskaya, V.P. (2002). PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 283(2), L354-L363.American Physiological Society. doi: 10.1152/ajplung.00010.2002.

Goncharova, E.A., Ammit, A.J., Irani, C., Carroll, R.G., Eszterhas, A.J., Panettieri, R.A., & Krymskaya, V.P. (2002). PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells. American Journal of Physiology - Lung Cellular and Molecular Physiology, 283(2 27-2). doi: 10.1152/ajplung.00010.2002.

Goncharova, E.A., Goncharov, D.A., Eszterhas, A., Hunter, D.S., Glassberg, M.K., Yeung, R.S., Walker, C.L., Noonan, D., Kwiatkowski, D.J., Chou, M.M., Panettieri, R.A., & Krymskaya, V.P. (2002). Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation - A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM). JOURNAL OF BIOLOGICAL CHEMISTRY, 277(34), 30958-30967.Elsevier BV. doi: 10.1074/jbc.M202678200.

Goncharova, E.A., Vorotnikov, A.V., Gracheva, E.O., Wang, C.L.A., Panettieri, R.A., Stepanova, V.V., & Tkachuk, V.A. (2002). Activation of p38 MAP-kinase and caldesmon phosphorylation are essential for urokinase-induced human smooth muscle cell migration. BIOLOGICAL CHEMISTRY, 383(1), 115-126.Walter de Gruyter GmbH. doi: 10.1515/BC.2002.012.

Irani, C., Goncharova, E.A., Hunter, D.S., Walker, C.L., Panettieri, R.A., & Krymskaya, V.P. (2002). Phosphatidylinositol 3-kinase but not tuberin is required for PDGF-induced cell migration. American Journal of Physiology - Lung Cellular and Molecular Physiology, 282(4 26-4). doi: 10.1152/ajplung.00291.2001.

Goncharova, E.A., Shirinsky, V.P., Shevelev, A.Y., Marston, S.B., & Vorotnikov, A.V. (2001). Actomyosin cross-linking by caldesmon in non-muscle cells. FEBS LETTERS, 497(2-3), 113-117.Wiley. doi: 10.1016/S0014-5793(01)02445-0.

Goncharova, E.A., Tkachuk, V.A., Ratner, E.I., Parfenova, E.V., & Vorotnikov, A.V. (2000). [The role of mitogen-activated protein kinases in stimulation of the smooth muscle cell migration by urokinase]. Zh Evol Biokhim Fiziol, 36(6), 569-575.

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