BSc in Electrical Engineering, University of Sao Paulo, 2006 - 2010
MSc in Electrical Engineering, University of Sao Paulo, 2012 - 2014
PhD in Bioengineering, University of Pittsburgh, 2014 - 2019
Chu, C., Santini, T., Liou, J.J., Cohen, A.D., Maki, P.M., Marsland, A.L., Thurston, R.C., Gianaros, P.J., & Ibrahim, T.S. (2025). Brain Morphometrics Correlations With Age Among 350 Participants Imaged With Both 3T and 7T MRI: 7T Improves Statistical Power and Reduces Required Sample Size. Hum Brain Mapp, 46(4), e70195.Wiley. doi: 10.1002/hbm.70195.
Diniz, E., Santini, T., Karim, H., Aizenstein, H.J., & Ibrahim, T.S. (2025). Cross-Modality Image Translation of 3 Tesla Magnetic Resonance Imaging to 7 Tesla Using Generative Adversarial Networks. Hum Brain Mapp, 46(9), e70246.Wiley. doi: 10.1002/hbm.70246.
Farhat, N., Li, J., Berardinelli, J., Stauffer, M., Sajewski, A., Alkhateeb, S., Schweitzer, N., Hecheng, J., Ikonomovic, M., Liou, J.J., Aizenstein, H.J., Mettenburg, J., Santini, T., Wu, M., Kofler, J., & Ibrahim, T.S. (2025). Bridging Neuroimaging and Neuropathology: A Comprehensive Workflow for Targeted Sampling of White Matter Lesions. In medRxiv. doi: 10.1101/2025.06.08.25329217.
Farhat, N., Li, J., Berardinelli, J., Stauffer, M., Sajewski, A., Alkhateeb, S., Schweitzer, N., Jin, H., Wood, S., Ikonomovic, M.D., Liou, J.J., Aizenstein, H.J., Mettenburg, J.M., Santini, T., Wu, M., Kofler, J.K., & Ibrahim, T.S. (2025). Bridging Neuroimaging and Neuropathology: A Comprehensive Workflow for Targeted Sampling of White Matter Lesions. J Neuroimaging, 35(5), e70094.Wiley. doi: 10.1111/jon.70094.
Sajewski, A.N., Santini, T., DeFranco, A., Berardinelli, J., Jin, H., Li, J., Chu, C., Berardo, J.J., & Ibrahim, T.S. (2025). RF shimming strategy for an open 60-channel RF transmit 7T MRI head coil for routine use on the single transmit mode. Magn Reson Med, 94(4), 1804-1816.Wiley. doi: 10.1002/mrm.30563.
Santini, T., Shim, A., Liou, J.J., Rahman, N., Varela-Mattatall, G., Budde, M.D., Inoue, W., Everling, S., & Baron, C.A. (2025). Investigating microstructural changes between in vivo and perfused ex vivo marmoset brains using oscillating gradient and b-tensor encoded diffusion MRI at 9.4 T. Magn Reson Med, 93(2), 788-802.Wiley. doi: 10.1002/mrm.30298.
Chu, C., Santini, T., Liou, J.J., Cohen, A.D., Maki, P.M., Marsland, A.L., Thurston, R.C., Gianaros, P.J., & Ibrahim, T.S. (2024). Brain morphometrics correlations with age among 352 participants imaged with both 3T and 7T MRI: 7T improves statistical power and reduces required sample size. In medRxiv. doi: 10.1101/2024.10.28.24316292.
Diniz, E., Santini, T., Helmet, K., Aizenstein, H.J., & Ibrahim, T.S. (2024). Cross-modality image translation of 3 Tesla Magnetic Resonance Imaging to 7 Tesla using Generative Adversarial Networks. In medRxiv. doi: 10.1101/2024.10.16.24315609.
Liang, L., Rollin, I.Z., Alikaya, A., Ho, J.C., Santini, T., Bostan, A.C., Schwerdt, H.N., Stauffer, W.R., Ibrahim, T.S., Pirondini, E., & Schaeffer, D.J. (2024). An open-source MRI compatible frame for multimodal presurgical mapping in macaque and capuchin monkeys. 2024.02.17.580767.Cold Spring Harbor Laboratory. doi: 10.1101/2024.02.17.580767.
Liou, J.J., Li, J., Berardinelli, J., Jin, H., Santini, T., Noh, J., Farhat, N., Wu, M., Aizenstein, H., Mettenburg, J.M., Yong, W., Head, E., Ikonomovic, M., Ibrahim, T., Kofler, J., & Alzheimer’s Biomarker Consortium on Down syndrome study. (2024). Correlating hippocampal and amygdala volumes with neuropathological burden in neurodegenerative diseases using 7T postmortem MRI. medRxiv, 2024.05.15.24307354.Cold Spring Harbor Laboratory. doi: 10.1101/2024.05.15.24307354.
Liou, J.J., Lou, J., Nakagiri, J., Yong, W., Hom, C.L., Doran, E.W., Totoiu, M., Lott, I., Mapstone, M., Keator, D.B., Brickman, A.M., Wright, S., Nelson, B., Lai, F., Xicota, L., Dang, L.H.T., Li, J., Santini, T., Mettenburg, J.M., Ikonomovic, M.D., Kofler, J., Ibrahim, T., Head, E., & Alzheimer Biomarker Consortium - Down Syndrome. (2024). A Neuropathology Case Report of a Woman with Down Syndrome who Remained Cognitively Stable. medRxiv, 2024.06.01.24308050.Cold Spring Harbor Laboratory. doi: 10.1101/2024.06.01.24308050.
Liou, J.J., Santini, T., Li, J., Gireud-Goss, M., Patel, V., Adeyemi, O.F., de Erausquin, G.A., Garbarino, V.R., Habes, M., Himali, J.J., Karmonik, C., Snitz, B.E., Mettenburg, J.M., Wu, M., Aizenstein, H.J., Marsland, A.L., Gianaros, P.J., Bowtell, R., Mougin, O., Vahidy, F.S., Girard, T.D., Jacobs, H.I.L., Hosseini, A.A., Seshadri, S., & Ibrahim, T.S. (2024). Examining Brain Structures and Cognitive Functions in Patients with Recovered COVID-19 Infection: A Multicenter Study Using 7T MRI. In medRxiv. doi: 10.1101/2024.11.13.24317121.
Sajewski, A.N., Santini, T., DeFranco, A., Berardinelli, J., Jin, H., Li, J., Chu, C., Berardo, J.J., & Ibrahim, T.S. (2024). RF shimming strategy for an open 60-channel RF transmit 7T head coil for routine use on the single transmit mode. In medRxiv. doi: 10.1101/2024.11.13.24316383.
Arezza, N.J.J., Santini, T., Omer, M., & Baron, C.A. (2023). Estimation of free water-corrected microscopic fractional anisotropy. Front Neurosci, 17, 1074730.Frontiers. doi: 10.3389/fnins.2023.1074730.
McGuigan, B.N., Santini, T., Keshavan, M.S., & Prasad, K.M. (2023). Gene Expressions Preferentially Influence Cortical Thickness of Human Connectome Project Atlas Parcellated Regions in First-Episode Antipsychotic-Naïve Psychoses. Schizophr Bull Open, 4(1), sgad019.Oxford University Press (OUP). doi: 10.1093/schizbullopen/sgad019.
Mani, A., Santini, T., Puppala, R., Dahl, M., Venkatesh, S., Walker, E., DeHaven, M., Isitan, C., Ibrahim, T.S., Wang, L., Zhang, T., Gong, E., Barrios-Martinez, J., Yeh, F.C., Krafty, R., Mettenburg, J.M., & Xia, Z. (2021). Applying Deep Learning to Accelerated Clinical Brain Magnetic Resonance Imaging for Multiple Sclerosis. Front Neurol, 12, 685276.Frontiers. doi: 10.3389/fneur.2021.685276.
Santini, T., Koo, M., Farhat, N., Campos, V.P., Alkhateeb, S., Vieira, M.A.C., Butters, M.A., Rosano, C., Aizenstein, H.J., Mettenburg, J., Novelli, E.M., & Ibrahim, T.S. (2021). Analysis of hippocampal subfields in sickle cell disease using ultrahigh field MRI. Neuroimage Clin, 30, 102655.Elsevier. doi: 10.1016/j.nicl.2021.102655.
Santini, T., Wood, S., Krishnamurthy, N., Martins, T., Aizenstein, H.J., & Ibrahim, T.S. (2021). Improved 7 Tesla transmit field homogeneity with reduced electromagnetic power deposition using coupled Tic Tac Toe antennas. Sci Rep, 11(1), 3370.Springer Nature. doi: 10.1038/s41598-020-79807-9.
Wood, S., Santini, T., Krishnamurthy, N., Martins, T., Farhat, N., & Ibrahim, T.S. (2021). A comprehensive electromagnetic evaluation of an MRI anthropomorphic head phantom. NMR Biomed, 34(3), e4441.Wiley. doi: 10.1002/nbm.4441.
Santini, T., Koo, M., Farhat, N., Campos, V.P., Alkhateeb, S., Vieira, M.A.C., Butters, M.A., Rosano, C., Aizenstein, H.J., Mettenburg, J., Novelli, E.M., & Ibrahim, T.S. (2020). Analysis of Hippocampal Subfields in Sickle Cell Disease Using Ultrahigh Field MRI. 2020.11.10.377564.Cold Spring Harbor Laboratory. doi: 10.1101/2020.11.10.377564.
Santini, T., Wood, S., Krishnamurthy, N., Martins, T., Aizenstein, H.J., & Ibrahim, T.S. (2020). Improved 7 Tesla Transmit Field Homogeneity with Reduced Electromagnetic Power Deposition Using Coupled Tic Tac Toe Antennas. 2020.11.06.371328.Cold Spring Harbor Laboratory. doi: 10.1101/2020.11.06.371328.
Smagula, S.F., Stahl, S.T., Santini, T., Banihashemi, L., Hall, M.H., Ibrahim, T.S., Reynolds, C.F., Krafty, R.T., Aizenstein, H.J., & Zhan, L. (2020). White Matter Integrity Underlying Depressive Symptoms in Dementia Caregivers. Am J Geriatr Psychiatry, 28(5), 578-582.Elsevier. doi: 10.1016/j.jagp.2019.11.010.
Borges, M.A., Prado, M., Santini, T.R.D.S., Barbosa, A.H.P., Moreira, A.C., Ishibe, E.I., Katz, M., & Cintra, F.D. (2019). Development and clinical validation of a non-invasive, beat-to-beat blood pressure monitoring device, compared to invasive blood pressure monitoring during coronary angiography. Einstein (Sao Paulo), 17(2), eAO4156.Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein. doi: 10.31744/einstein_journal/2019AO4156.
Farhat, N.S., Theiss, R., Santini, T., Ibrahim, T.S., & Aizenstein, H.J. (2019). Neuroimaging of Small Vessel Disease in Late-Life Depression. Adv Exp Med Biol, 1192, 95-115.Springer Nature. doi: 10.1007/978-981-32-9721-0_5.
Krishnamurthy, N., Santini, T., Wood, S., Kim, J., Zhao, T., Aizenstein, H.J., & Ibrahim, T.S. (2019). Computational and experimental evaluation of the Tic-Tac-Toe RF coil for 7 Tesla MRI. In Orzada, S. (Ed.). PLoS One, 14(1), e0209663.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0209663.
Santini, T., Kim, J., Wood, S., Krishnamurthy, N., Farhat, N., Maciel, C., Raval, S.B., Zhao, T., & Ibrahim, T.S. (2018). A new RF transmit coil for foot and ankle imaging at 7T MRI. Magn Reson Imaging, 45, 1-6.Elsevier. doi: 10.1016/j.mri.2017.09.005.
Santini, T., Zhao, Y., Wood, S., Krishnamurthy, N., Kim, J., Farhat, N., Alkhateeb, S., Martins, T., Koo, M., Zhao, T., Aizenstein, H.J., & Ibrahim, T.S. (2018). In-vivo and numerical analysis of the eigenmodes produced by a multi-level Tic-Tac-Toe head transmit array for 7 Tesla MRI. In Lundberg, P. (Ed.). PLoS One, 13(11), e0206127.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0206127.
Smagula, S.F., Karim, H.T., Rangarajan, A., Santos, F.P., Wood, S.C., Santini, T., Jakicic, J.M., Reynolds, C.F., Cameron, J.L., Vallejo, A.N., Butters, M.A., Rosano, C., Ibrahim, T.S., Erickson, K.I., & Aizenstein, H.J. (2018). Association of Hippocampal Substructure Resting-State Functional Connectivity with Memory Performance in Older Adults. Am J Geriatr Psychiatry, 26(6), 690-699.Elsevier. doi: 10.1016/j.jagp.2018.03.003.
Kim, J., Santini, T., Bae, K.T., Krishnamurthy, N., Zhao, Y., Zhao, T., & Ibrahim, T.S. (2017). Development of a 7 T RF coil system for breast imaging. NMR Biomed, 30(1).Wiley. doi: 10.1002/nbm.3664.
Raval, S.B., Britton, C.A., Zhao, T., Krishnamurthy, N., Santini, T., Gorantla, V.S., & Ibrahim, T.S. (2017). Ultra-high field upper extremity peripheral nerve and non-contrast enhanced vascular imaging. In Lin, F.H. (Ed.). PLoS One, 12(6), e0175629.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0175629.
Wood, S., Krishnamurthy, N., Santini, T., Raval, S.B., Farhat, N., Holmes, J.A., & Ibrahim, T.S. (2017). Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes. In Lundberg, P. (Ed.). PLoS One, 12(8), e0183168.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0183168.
Kim, J., Krishnamurthy, N., Santini, T., Zhao, Y., Zhao, T., Bae, K.T., & Ibrahim, T.S. (2016). Experimental and numerical analysis of B1(+) field and SAR with a new transmit array design for 7T breast MRI. J Magn Reson, 269, 55-64.Elsevier. doi: 10.1016/j.jmr.2016.04.012.
Santini, T.R.S., Ibrahim, T.S., & Maciel, C.D. (2016). Load-insensitive active quasi-circulator for continuous-wave Doppler ultrasound applications. ELECTRONICS LETTERS, 52(22), 1823-1824.Institution of Engineering and Technology (IET). doi: 10.1049/el.2016.2574.
de Souza Santini, T.R. (2014). Projeto e análise de aplicações de circuladores ativos para a operação em frequências de ultrassom Doppler de ondas contínuas. Universidade de Sao Paulo, Agencia USP de Gestao da Informacao Academica (AGUIA).
Filho, M.A.O., Marra, A.R., Magnus, T.P., Rodrigues, R.D., Prado, M., de Souza Santini, T.R., da Silva Victor, E., Ishibe, E.I., Pavão Dos Santos, O.F., & Edmond, M.B. (2014). Comparison of human and electronic observation for the measurement of compliance with hand hygiene. Am J Infect Control, 42(11), 1188-1192.Elsevier. doi: 10.1016/j.ajic.2014.07.031.
