Subhadip Ghatak

Ghatak, S. (2024). Decoding the healing dialogues for tissue repair. Mol Ther, 32(9), 2814-2816.Elsevier. doi: 10.1016/j.ymthe.2024.08.008.

Sharma, A., Srivastava, R., Gnyawali, S.C., Bhasme, P., Anthony, A.J., Xuan, Y., Trinidad, J.C., Sen, C.K., Clemmer, D.E., Roy, S., & Ghatak, S. (2024). Mitochondrial Bioenergetics of Functional Wound Closure is Dependent on Macrophage-Keratinocyte Exosomal Crosstalk. ACS Nano, 18(44), 30405-30420.American Chemical Society (ACS). doi: 10.1021/acsnano.4c07610.

Sharma, A., Yadav, A., Nandy, A., & Ghatak, S. (2024). Insight into the Functional Dynamics and Challenges of Exosomes in Pharmaceutical Innovation and Precision Medicine. Pharmaceutics, 16(6), 709.MDPI. doi: 10.3390/pharmaceutics16060709.

Welsh, J.A., Goberdhan, D.C.I., O'Driscoll, L., Buzas, E.I., Blenkiron, C., Bussolati, B., Cai, H., Di Vizio, D., Driedonks, T.A.P., Erdbrügger, U., Falcon-Perez, J.M., Fu, Q.L., Hill, A.F., Lenassi, M., Lim, S.K., Mahoney, M.G., Mohanty, S., Möller, A., Nieuwland, R., Ochiya, T., Sahoo, S., Torrecilhas, A.C., Zheng, L., Zijlstra, A., Abuelreich, S., Bagabas, R., Bergese, P., Bridges, E.M., Brucale, M., Burger, D., Carney, R.P., Cocucci, E., Crescitelli, R., Hanser, E., Harris, A.L., Haughey, N.J., Hendrix, A., Ivanov, A.R., Jovanovic-Talisman, T., Kruh-Garcia, N.A., Ku'ulei-Lyn Faustino, V., Kyburz, D., Lässer, C., Lennon, K.M., Lötvall, J., Maddox, A.L., Martens-Uzunova, E.S., Mizenko, R.R., Newman, L.A., Ridolfi, A., Rohde, E., Rojalin, T., Rowland, A., Saftics, A., Sandau, U.S., Saugstad, J.A., Shekari, F., Swift, S., Ter-Ovanesyan, D., Tosar, J.P., Useckaite, Z., Valle, F., Varga, Z., van der Pol, E., van Herwijnen, M.J.C., Wauben, M.H.M., Wehman, A.M., Williams, S., Zendrini, A., Zimmerman, A.J., MISEV Consortium, Théry, C., & Witwer, K.W. (2024). Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. J Extracell Vesicles, 13(2), e12404.Wiley. doi: 10.1002/jev2.12404.

Xuan, Y., Wang, C., Ghatak, S., & Sen, C.K. (2024). Tissue Nanotransfection Silicon Chip and Related Electroporation-Based Technologies for In Vivo Tissue Reprogramming. Nanomaterials (Basel), 14(2), 217.MDPI. doi: 10.3390/nano14020217.

Yadav, A., Nandy, A., Sharma, A., & Ghatak, S. (2024). Exosome Mediated Cell-Cell Crosstalk in Tissue Injury and Repair. Results Probl Cell Differ, 73, 249-297.Springer Nature. doi: 10.1007/978-3-031-62036-2_12.

Yadav, A., Xuan, Y., Sen, C.K., & Ghatak, S. (2024). Standardized Reporting of Research on Exosomes to Ensure Rigor and Reproducibility. Adv Wound Care (New Rochelle), 13(11), 584-599.Mary Ann Liebert. doi: 10.1089/wound.2024.0093.

Anthony, A.J., Gautam, A.K.S., Miller, L.M., Ma, Y., Hardwick, A.G., Sharma, A., Ghatak, S., Matouschek, A., Jarrold, M.F., & Clemmer, D.E. (2023). CDMS Analysis of Intact 19S, 20S, 26S, and 30S Proteasomes: Evidence for Higher-Order 20S Assemblies at a Low pH†. Anal Chem, 95(33), 12209-12215.American Chemical Society (ACS). doi: 10.1021/acs.analchem.3c00472.

Ghatak, S., Hemann, C., Boslett, J., Singh, K., Sharma, A., El Masry, M.S., Abouhashem, A.S., Ghosh, N., Mathew-Steiner, S.S., Roy, S., Zweier, J.L., & Sen, C.K. (2023). Bacterial Pyocyanin Inducible Keratin 6A Accelerates Closure of Epithelial Defect under Conditions of Mitochondrial Dysfunction. J Invest Dermatol, 143(10), 2052-2064.e5.Elsevier. doi: 10.1016/j.jid.2023.03.1671.

Ghatak, S., Khanna, S., Roy, S., Thirunavukkarasu, M., Pradeep, S.R., Wulff, B.C., El Masry, M.S., Sharma, A., Palakurti, R., Ghosh, N., Xuan, Y., Wilgus, T.A., Maulik, N., Yoder, M.C., & Sen, C.K. (2023). Driving adult tissue repair via re-engagement of a pathway required for fetal healing. Mol Ther, 31(2), 454-470.Elsevier. doi: 10.1016/j.ymthe.2022.09.002.

Gnyawali, S.C., Denune, J.A., Hockman, B., Kristjánsdóttir, J.V., Ragnarsdóttir, M.S., Timsina, L.R., Ghatak, S., Lechler, K., Sen, C.K., & Roy, S. (2023). Moisture mitigation using a vented liner and a vented socket system for individuals with transfemoral amputation. Sci Rep, 13(1), 16557.Springer Nature. doi: 10.1038/s41598-023-43572-2.

Gordillo, G.M., Guda, P.R., Singh, K., Biswas, A., Abouhashem, A.S., Rustagi, Y., Sen, A., Kumar, M., Das, A., Ghatak, S., Khanna, S., Sen, C.K., & Roy, S. (2023). Tissue nanotransfection causes tumor regression by its effect on nanovesicle cargo that alters microenvironmental macrophage state. Mol Ther, 31(5), 1402-1417.Elsevier. doi: 10.1016/j.ymthe.2022.11.003.

Guda, P.R., Sharma, A., Anthony, A.J., ElMasry, M.S., Couse, A.D., Ghatak, P.D., Das, A., Timsina, L., Trinidad, J.C., Roy, S., Clemmer, D.E., Sen, C.K., & Ghatak, S. (2023). Nanoscopic and Functional Characterization of Keratinocyte-Originating Exosomes in the Wound Fluid of Non-Diabetic and Diabetic Chronic Wound Patients. Nano Today, 52, 101954.Elsevier. doi: 10.1016/j.nantod.2023.101954.

Pal, D., Ghatak, S., Singh, K., Abouhashem, A.S., Kumar, M., El Masry, M.S., Mohanty, S.K., Palakurti, R., Rustagi, Y., Tabasum, S., Khona, D.K., Khanna, S., Kacar, S., Srivastava, R., Bhasme, P., Verma, S.S., Hernandez, E., Sharma, A., Reese, D., Verma, P., Ghosh, N., Gorain, M., Wan, J., Liu, S., Liu, Y., Castro, N.H., Gnyawali, S.C., Lawrence, W., Moore, J., Perez, D.G., Roy, S., Yoder, M.C., & Sen, C.K. (2023). Identification of a physiologic vasculogenic fibroblast state to achieve tissue repair. Nat Commun, 14(1), 1129.Springer Nature. doi: 10.1038/s41467-023-36665-z.

Palakurti, R., Biswas, N., Roy, S., Gnyawali, S.C., Sinha, M., Singh, K., Ghatak, S., Sen, C.K., & Khanna, S. (2023). Inducible miR-1224 silences cerebrovascular Serpine1 and restores blood flow to the stroke-affected site of the brain. Mol Ther Nucleic Acids, 31, 276-292.Elsevier. doi: 10.1016/j.omtn.2022.12.019.

Srivastava, R., Singh, K., Abouhashem, A.S., Kumar, M., Kacar, S., Verma, S.S., Mohanty, S.K., Sinha, M., Ghatak, S., Xuan, Y., & Sen, C.K. (2023). Human fetal dermal fibroblast-myeloid cell diversity is characterized by dominance of pro-healing Annexin1-FPR1 signaling. iScience, 26(9), 107533.Elsevier. doi: 10.1016/j.isci.2023.107533.

van der Elst, L.A., Gokce, M., Coulter, J.R., Cavdar, Z.B., Koraganji, V.N., Ozturk, M., Ghatak, S., Sen, C.K., & Gumennik, A. (2023). Microstructured Electroceutical Fiber-Device for Inhibition of Bacterial Proliferation in Wounds. ADVANCED MATERIALS INTERFACES, 10(3).Wiley. doi: 10.1002/admi.202201854.

Brown, B.A., Guda, P.R., Zeng, X., Anthony, A., Couse, A., Barnes, L.F., Sharon, E.M., Trinidad, J.C., Sen, C.K., Jarrold, M.F., Ghatak, S., & Clemmer, D.E. (2022). Analysis of Keratinocytic Exosomes from Diabetic and Nondiabetic Mice by Charge Detection Mass Spectrometry. Anal Chem, 94(25), 8909-8918.American Chemical Society (ACS). doi: 10.1021/acs.analchem.2c00453.

Clark, A., Ghatak, S., Guda, P.R., El Masry, M.S., Xuan, Y., Sato, A.Y., Bellido, T., & Sen, C.K. (2022). Myogenic tissue nanotransfection improves muscle torque recovery following volumetric muscle loss. NPJ Regen Med, 7(1), 63.Springer Nature. doi: 10.1038/s41536-022-00259-y.

Li, Z., Xuan, Y., Ghatak, S., Guda, P.R., Roy, S., & Sen, C.K. (2022). Modeling the gene delivery process of the needle array-based tissue nanotransfection. Nano Res, 15(4), 3409-3421.Tsinghua University Press. doi: 10.1007/s12274-021-3947-1.

Santra, A., Bishnu, D., Santra, S., Ghatak, S., Mukherjee, P.S., Dhali, G.K., & Chowdhury, A. (2022). Arsenic-Induced Injury of Mouse Hepatocytes through Lysosome and Mitochondria: An In Vitro Study. In Uhlmann, D. (Ed.). Int J Hepatol, 2022(1), 1546297.Hindawi. doi: 10.1155/2022/1546297.

Singh, K., Rustagi, Y., Abouhashem, A.S., Tabasum, S., Verma, P., Hernandez, E., Pal, D., Khona, D.K., Mohanty, S.K., Kumar, M., Srivastava, R., Guda, P.R., Verma, S.S., Mahajan, S., Killian, J.A., Walker, L.A., Ghatak, S., Mathew-Steiner, S.S., Wanczyk, K.E., Liu, S., Wan, J., Yan, P., Bundschuh, R., Khanna, S., Gordillo, G.M., Murphy, M.P., Roy, S., & Sen, C.K. (2022). Genome-wide DNA hypermethylation opposes healing in patients with chronic wounds by impairing epithelial-mesenchymal transition. J Clin Invest, 132(17), e157279.American Society for Clinical Investigation. doi: 10.1172/JCI157279.

Ghatak, S., Khona, D.K., Sen, A., Huang, K., Jagdale, G., Singh, K., Gopalakrishnan, V., Cornetta, K.G., Roy, S., Khanna, S., Baker, L.A., & Sen, C.K. (2021). Electroceutical fabric lowers zeta potential and eradicates coronavirus infectivity upon contact. Sci Rep, 11(1), 21723.Springer Nature. doi: 10.1038/s41598-021-00910-6.

Khona, D.K., Roy, S., Ghatak, S., Huang, K., Jagdale, G., Baker, L.A., & Sen, C.K. (2021). Ketoconazole resistant Candida albicans is sensitive to a wireless electroceutical wound care dressing. Bioelectrochemistry, 142, 107921.Elsevier. doi: 10.1016/j.bioelechem.2021.107921.

Xuan, Y., Ghatak, S., Clark, A., Li, Z., Khanna, S., Pak, D., Agarwal, M., Roy, S., Duda, P., & Sen, C.K. (2021). Fabrication and use of silicon hollow-needle arrays to achieve tissue nanotransfection in mouse tissue in vivo. Nat Protoc, 16(12), 5707-5738.Springer Nature. doi: 10.1038/s41596-021-00631-0.

Deng, B., Ghatak, S., Sarkar, S., Singh, K., Das Ghatak, P., Mathew-Steiner, S.S., Roy, S., Khanna, S., Wozniak, D.J., McComb, D.W., & Sen, C.K. (2020). Novel Bacterial Diversity and Fragmented eDNA Identified in Hyperbiofilm-Forming Pseudomonas aeruginosa Rugose Small Colony Variant. iScience, 23(2), 100827.Elsevier. doi: 10.1016/j.isci.2020.100827.

Gnyawali, S.C., Sinha, M., El Masry, M.S., Wulff, B., Ghatak, S., Soto-Gonzalez, F., Wilgus, T.A., Roy, S., & Sen, C.K. (2020). High resolution ultrasound imaging for repeated measure of wound tissue morphometry, biomechanics and hemodynamics under fetal, adult and diabetic conditions. In Stevenson, G.N. (Ed.). PLoS One, 15(11), e0241831.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0241831.

Gupta, S., Ghatak, S., Hery, T., Khanna, S., El Masry, M., Sundaresan, V.B., & Sen, C.K. (2020). Ad hoc hybrid synaptic junctions to detect nerve stimulation and its application to detect onset of diabetic polyneuropathy. Biosens Bioelectron, 169, 112618.Elsevier. doi: 10.1016/j.bios.2020.112618.

Roy, S., Santra, S., Das, A., Dixith, S., Sinha, M., Ghatak, S., Ghosh, N., Banerjee, P., Khanna, S., Mathew-Steiner, S., Ghatak, P.D., Blackstone, B.N., Powell, H.M., Bergdall, V.K., Wozniak, D.J., & Sen, C.K. (2020). Staphylococcus aureus Biofilm Infection Compromises Wound Healing by Causing Deficiencies in Granulation Tissue Collagen. Ann Surg, 271(6), 1174-1185.Wolters Kluwer. doi: 10.1097/SLA.0000000000003053.

Roy, S., Sen, C.K., Ghatak, S., Higuita-Castro, N., Palakurti, R., Nalluri, N., Clark, A., Stewart, R., Gallego-Perez, D., Prater, D.N., & Khanna, S. (2020). Neurogenic tissue nanotransfection in the management of cutaneous diabetic polyneuropathy. Nanomedicine, 28, 102220.Elsevier. doi: 10.1016/j.nano.2020.102220.

Zhou, X., Brown, B.A., Siegel, A.P., El Masry, M.S., Zeng, X., Song, W., Das, A., Khandelwal, P., Clark, A., Singh, K., Guda, P.R., Gorain, M., Timsina, L., Xuan, Y., Jacobson, S.C., Novotny, M.V., Roy, S., Agarwal, M., Lee, R.J., Sen, C.K., Clemmer, D.E., & Ghatak, S. (2020). Exosome-Mediated Crosstalk between Keratinocytes and Macrophages in Cutaneous Wound Healing. ACS Nano, 14(10), 12732-12748.American Chemical Society (ACS). doi: 10.1021/acsnano.0c03064.

Das, A., S El Masry, M., Gnyawali, S.C., Ghatak, S., Singh, K., Stewart, R., Lewis, M., Saha, A., Gordillo, G., & Khanna, S. (2019). Skin Transcriptome of Middle-Aged Women Supplemented With Natural Herbo-mineral Shilajit Shows Induction of Microvascular and Extracellular Matrix Mechanisms. J Am Coll Nutr, 38(6), 526-536.Taylor & Francis. doi: 10.1080/07315724.2018.1564088.

Zgheib, C., Hilton, S.A., Dewberry, L.C., Hodges, M.M., Ghatak, S., Xu, J., Singh, S., Roy, S., Sen, C.K., Seal, S., & Liechty, K.W. (2019). Use of Cerium Oxide Nanoparticles Conjugated with MicroRNA-146a to Correct the Diabetic Wound Healing Impairment. J Am Coll Surg, 228(1), 107-115.Wolters Kluwer. doi: 10.1016/j.jamcollsurg.2018.09.017.

Li, J., Ghatak, S., El Masry, M.S., Das, A., Liu, Y., Roy, S., Lee, R.J., & Sen, C.K. (2018). Topical Lyophilized Targeted Lipid Nanoparticles in the Restoration of Skin Barrier Function following Burn Wound. Mol Ther, 26(9), 2178-2188.Elsevier. doi: 10.1016/j.ymthe.2018.04.021.

Sinha, M., Sen, C.K., Singh, K., Das, A., Ghatak, S., Rhea, B., Blackstone, B., Powell, H.M., Khanna, S., & Roy, S. (2018). Direct conversion of injury-site myeloid cells to fibroblast-like cells of granulation tissue. Nat Commun, 9(1), 936.Springer Nature. doi: 10.1038/s41467-018-03208-w.

Ahmed, N.S., Ghatak, S., El Masry, M.S., Gnyawali, S.C., Roy, S., Amer, M., Everts, H., Sen, C.K., & Khanna, S. (2017). Epidermal E-Cadherin Dependent β-Catenin Pathway Is Phytochemical Inducible and Accelerates Anagen Hair Cycling. Mol Ther, 25(11), 2502-2512.Elsevier. doi: 10.1016/j.ymthe.2017.07.010.

Gallego-Perez, D., Pal, D., Ghatak, S., Malkoc, V., Higuita-Castro, N., Gnyawali, S., Chang, L., Liao, W.C., Shi, J., Sinha, M., Singh, K., Steen, E., Sunyecz, A., Stewart, R., Moore, J., Ziebro, T., Northcutt, R.G., Homsy, M., Bertani, P., Lu, W., Roy, S., Khanna, S., Rink, C., Sundaresan, V.B., Otero, J.J., Lee, L.J., & Sen, C.K. (2017). Topical tissue nano-transfection mediates non-viral stroma reprogramming and rescue. Nat Nanotechnol, 12(10), 974-979.Springer Nature. doi: 10.1038/nnano.2017.134.

Gnyawali, S.C., Blum, K., Pal, D., Ghatak, S., Khanna, S., Roy, S., & Sen, C.K. (2017). Retooling Laser Speckle Contrast Analysis Algorithm to Enhance Non-Invasive High Resolution Laser Speckle Functional Imaging of Cutaneous Microcirculation. Sci Rep, 7(1), 41048.Springer Nature. doi: 10.1038/srep41048.

Singh, K., Pal, D., Sinha, M., Ghatak, S., Gnyawali, S.C., Khanna, S., Roy, S., & Sen, C.K. (2017). Epigenetic Modification of MicroRNA-200b Contributes to Diabetic Vasculopathy. Mol Ther, 25(12), 2689-2704.Elsevier. doi: 10.1016/j.ymthe.2017.09.009.

Das, A., Ghatak, S., Sinha, M., Chaffee, S., Ahmed, N.S., Parinandi, N.L., Wohleb, E.S., Sheridan, J.F., Sen, C.K., & Roy, S. (2016). Correction of MFG-E8 Resolves Inflammation and Promotes Cutaneous Wound Healing in Diabetes. J Immunol, 196(12), 5089-5100.The American Association of Immunologists. doi: 10.4049/jimmunol.1502270.

Gallego-Perez, D., Otero, J.J., Czeisler, C., Ma, J., Ortiz, C., Gygli, P., Catacutan, F.P., Gokozan, H.N., Cowgill, A., Sherwood, T., Ghatak, S., Malkoc, V., Zhao, X., Liao, W.C., Gnyawali, S., Wang, X., Adler, A.F., Leong, K., Wulff, B., Wilgus, T.A., Askwith, C., Khanna, S., Rink, C., Sen, C.K., & Lee, L.J. (2016). Deterministic transfection drives efficient nonviral reprogramming and uncovers reprogramming barriers. Nanomedicine, 12(2), 399-409.Elsevier. doi: 10.1016/j.nano.2015.11.015.

Ghatak, S., Li, J., Chan, Y.C., Gnyawali, S.C., Steen, E., Yung, B.C., Khanna, S., Roy, S., Lee, R.J., & Sen, C.K. (2016). AntihypoxamiR functionalized gramicidin lipid nanoparticles rescue against ischemic memory improving cutaneous wound healing. Nanomedicine, 12(7), 1827-1831.Elsevier. doi: 10.1016/j.nano.2016.03.004.

Sen, C.K., Ghatak, S., Gnyawali, S.C., Roy, S., & Gordillo, G.M. (2016). Cutaneous Imaging Technologies in Acute Burn and Chronic Wound Care. Plast Reconstr Surg, 138(3 Suppl), 119S-128S.Wolters Kluwer. doi: 10.1097/PRS.0000000000002654.

Ghatak, S., Chan, Y.C., Khanna, S., Banerjee, J., Weist, J., Roy, S., & Sen, C.K. (2015). Barrier Function of the Repaired Skin Is Disrupted Following Arrest of Dicer in Keratinocytes. Mol Ther, 23(7), 1201-1210.Elsevier. doi: 10.1038/mt.2015.65.

Sen, C.K., & Ghatak, S. (2015). miRNA control of tissue repair and regeneration. Am J Pathol, 185(10), 2629-2640.Elsevier. doi: 10.1016/j.ajpath.2015.04.001.

Sinha, M., Ghatak, S., Roy, S., & Sen, C.K. (2015). microRNA-200b as a Switch for Inducible Adult Angiogenesis. Antioxid Redox Signal, 22(14), 1257-1272.Mary Ann Liebert. doi: 10.1089/ars.2014.6065.

Ghatak, S., Biswas, A., Dhali, G.K., Chowdhury, A., Boyer, J.L., & Santra, A. (2011). Oxidative stress and hepatic stellate cell activation are key events in arsenic induced liver fibrosis in mice. Toxicol Appl Pharmacol, 251(1), 59-69.Elsevier. doi: 10.1016/j.taap.2010.11.016.

Santra, A., Chowdhury, A., Ghatak, S., Biswas, A., & Dhali, G.K. (2007). Arsenic induces apoptosis in mouse liver is mitochondria dependent and is abrogated by N-acetylcysteine. Toxicol Appl Pharmacol, 220(2), 146-155.Elsevier. doi: 10.1016/j.taap.2006.12.029.

Chowdhury, A., Santra, A., Bhattacharjee, K., Ghatak, S., Saha, D.R., & Dhali, G.K. (2006). Mitochondrial oxidative stress and permeability transition in isoniazid and rifampicin induced liver injury in mice. J Hepatol, 45(1), 117-126.Elsevier. doi: 10.1016/j.jhep.2006.01.027.

Samanta, A.K., Dhargupta, K.K., & Ghatak, S. (2001). In situ development of SiC-mullite composites in ambient atmosphere from SiC and Al-hydroxyhydrogel powder precursor. Journal of Materials Science Letters, 20(22), 2077-2080.Springer Nature. doi: 10.1023/a:1013566729914.

Ghatak, S., & Ho, S.M. (1996). Age-related changes in the activities of antioxidant enzymes and lipid peroxidation status in ventral and dorsolateral prostate lobes of noble rats. Biochem Biophys Res Commun, 222(2), 362-367.Elsevier. doi: 10.1006/bbrc.1996.0749.