Paul E Torgersen Research Excellence Award.
B.E., Anna University, 2011
Ph.D., Virginia Tech - Wake Forest University, 2016
Mills, A., & George, S.A. (2025). Quadruple Parametric Optical Mapping to Measure Cardiac Metabolism-Excitation-Contraction Coupling. In bioRxiv. doi: 10.1101/2025.03.12.642802.
Fullenkamp, D.E., Maeng, W.Y., Oh, S., Luan, H., Kim, K.S., Chychula, I.A., Kim, J.T., Yoo, J.Y., Holgren, C.W., Demonbreun, A.R., George, S., Li, B., Hsu, Y., Chung, G., Yoo, J., Koo, J., Park, Y., Efimov, I.R., McNally, E.M., & Rogers, J.A. (2024). Simultaneous electromechanical monitoring in engineered heart tissues using a mesoscale framework. Sci Adv, 10(37), eado7089.American Association for the Advancement of Science (AAAS). doi: 10.1126/sciadv.ado7089.
George, S.A., Trampel, K.A., Brunner, K., & Efimov, I.R. (2024). Moderate Endurance Exercise Increases Arrhythmia Susceptibility and Modulates Cardiac Structure and Function in a Sexually Dimorphic Manner. J Am Heart Assoc, 13(9), e033317.Wolters Kluwer. doi: 10.1161/JAHA.123.033317.
Chen, Z., Lin, Z., Obaid, S.N., Rytkin, E., George, S.A., Bach, C., Madrid, M., Liu, M., LaPiano, J., Fehr, A., Shi, X., Quirion, N., Russo, B., Knight, H., Aduwari, A., Efimov, I.R., & Lu, L. (2023). Soft, bioresorbable, transparent microelectrode arrays for multimodal spatiotemporal mapping and modulation of cardiac physiology. Sci Adv, 9(27), eadi0757.American Association for the Advancement of Science (AAAS). doi: 10.1126/sciadv.adi0757.
George, S.A., Brennan-McLean, J.A., Trampel, K.A., Rytkin, E., Faye, N.R., Knollmann, B.C., & Efimov, I.R. (2023). Ryanodine receptor inhibition with acute dantrolene treatment reduces arrhythmia susceptibility in human hearts. Am J Physiol Heart Circ Physiol, 325(4), H720-H728.American Physiological Society. doi: 10.1152/ajpheart.00103.2023.
George, S.A., Kiss, A., Trampel, K.A., Obaid, S.N., Tang, L., Efimov, I.R., & Efimova, T. (2023). Anthracycline cardiotoxicity is exacerbated by global p38β genetic ablation in a sexually dimorphic manner but unaltered by cardiomyocyte-specific p38α loss. Am J Physiol Heart Circ Physiol, 325(5), H983-H997.American Physiological Society. doi: 10.1152/ajpheart.00458.2023.
George, S.A., Trampel, K.A., Brunner, K., & Efimov, I.R. (2023). Moderate Endurance Exercise Increases Arrhythmia Susceptibility and modulates Cardiac Structure and Function in a Sexually Dimorphic manner. 2023.08.21.554195.Cold Spring Harbor Laboratory. doi: 10.1101/2023.08.21.554195.
George, S.A., Lin, Z., & Efimov, I.R. (2022). Simultaneous triple-parametric optical mapping of transmembrane potential, intracellular calcium and NADH for cardiac physiology assessment. Commun Biol, 5(1), 319.Springer Nature. doi: 10.1038/s42003-022-03279-y.
George, S.A., Lin, Z., & Efimov, I.R. (2021). Simultaneous Triple-Parametric Optical Mapping of Transmembrane Potential, Intracellular Calcium and NADH for Cardiac Physiology Assessment. 2021.09.09.459667.Cold Spring Harbor Laboratory. doi: 10.1101/2021.09.09.459667.
Warhol, A., George, S.A., Obaid, S.N., Efimova, T., & Efimov, I.R. (2021). Differential cardiotoxic electrocardiographic response to doxorubicin treatment in conscious versus anesthetized mice. Physiol Rep, 9(15), e14987.Wiley. doi: 10.14814/phy2.14987.
George, S.A., Brennan, J.A., & Efimov, I.R. (2020). Preclinical Cardiac Electrophysiology Assessment by Dual Voltage and Calcium Optical Mapping of Human Organotypic Cardiac Slices. J Vis Exp, (160).MyJove. doi: 10.3791/60781.
George, S.A., Kiss, A., Obaid, S.N., Venegas, A., Talapatra, T., Wei, C., Efimova, T., & Efimov, I.R. (2020). p38δ genetic ablation protects female mice from anthracycline cardiotoxicity. 2020.03.02.973347.Cold Spring Harbor Laboratory. doi: 10.1101/2020.03.02.973347.
Miller, J.M., Meki, M.H., Ou, Q., George, S.A., Gams, A., Abouleisa, R.R.E., Tang, X.L., Ahern, B.M., Giridharan, G.A., El-Baz, A., Hill, B.G., Satin, J., Conklin, D.J., Moslehi, J., Bolli, R., Ribeiro, A.J.S., Efimov, I.R., & Mohamed, T.M.A. (2020). Heart slice culture system reliably demonstrates clinical drug-related cardiotoxicity. Toxicol Appl Pharmacol, 406, 115213.Elsevier. doi: 10.1016/j.taap.2020.115213.
Cathey, B., Obaid, S., Zolotarev, A.M., Pryamonosov, R.A., Syunyaev, R.A., George, S.A., & Efimov, I.R. (2019). Open-Source Multiparametric Optocardiography. Sci Rep, 9(1), 721.Springer Nature. doi: 10.1038/s41598-018-36809-y.
Efimov, I.R., & George, S. (2018). Authors' Reply: Unravelling the Mysteries of the Human AV Node. Arrhythm Electrophysiol Rev, 7(1), 63-64.Radcliffe Cardiology. doi: 10.15420/aer.2018.7.1.L1.R1.
George, S.A., Calhoun, P.J., Gourdie, R.G., Smyth, J.W., & Poelzing, S. (2017). TNFα Modulates Cardiac Conduction by Altering Electrical Coupling between Myocytes. Front Physiol, 8, 334.Frontiers. doi: 10.3389/fphys.2017.00334.
George, S.A., Faye, N.R., Murillo-Berlioz, A., Lee, K.B., Trachiotis, G.D., & Efimov, I.R. (2017). At the Atrioventricular Crossroads: Dual Pathway Electrophysiology in the Atrioventricular Node and its Underlying Heterogeneities. Arrhythm Electrophysiol Rev, 6(4), 179-185.Radcliffe Cardiology. doi: 10.15420/aer.2017.30.1.
Greer-Short, A., George, S.A., Poelzing, S., & Weinberg, S.H. (2017). Revealing the Concealed Nature of Long-QT Type 3 Syndrome. Circ Arrhythm Electrophysiol, 10(2), e004400.Wolters Kluwer. doi: 10.1161/CIRCEP.116.004400.
Entz, M., George, S.A., Zeitz, M.J., Raisch, T., Smyth, J.W., & Poelzing, S. (2016). Heart Rate and Extracellular Sodium and Potassium Modulation of Gap Junction Mediated Conduction in Guinea Pigs. Front Physiol, 7, 16.Frontiers. doi: 10.3389/fphys.2016.00016.
George, S.A., & Poelzing, S. (2016). Cardiac conduction in isolated hearts of genetically modified mice--Connexin43 and salts. Prog Biophys Mol Biol, 120(1-3), 189-198.Elsevier. doi: 10.1016/j.pbiomolbio.2015.11.004.
George, S.A., Bonakdar, M., Zeitz, M., Davalos, R.V., Smyth, J.W., & Poelzing, S. (2016). Extracellular sodium dependence of the conduction velocity-calcium relationship: evidence of ephaptic self-attenuation. Am J Physiol Heart Circ Physiol, 310(9), H1129-H1139.American Physiological Society. doi: 10.1152/ajpheart.00857.2015.
George, S.A., Sciuto, K.J., Lin, J., Salama, M.E., Keener, J.P., Gourdie, R.G., & Poelzing, S. (2015). Extracellular sodium and potassium levels modulate cardiac conduction in mice heterozygous null for the Connexin43 gene. Pflugers Arch, 467(11), 2287-2297.Springer Nature. doi: 10.1007/s00424-015-1698-0.