headshot of Shaohua Pi

Shaohua Pi

Assistant Professor
SHAOHUA@pitt.edu
(724) 719-4817
Bioengineering Department

overview

I lead the Pitt OCT lab that pursues the development of optical coherence tomography (OCT) techniques and their applications in ophthalmology.

about

PhD, Fudan University

BS, Fudan University

Wang, B., Arbuckle, R.K., Davoli, K.A., Clinger, O.D., Brown, R., Sahel, J.A., Chen, Y., & Pi, S. (2024). Compensation of inner retina to early-stage photoreceptor degeneration in a RhoP23H/+ mouse model of retinitis pigmentosa. Exp Eye Res, 240, 109826.Elsevier BV. doi: 10.1016/j.exer.2024.109826.

Wang, B., Brown, R., Chhablani, J., & Pi, S. (2023). Volumetrically tracking retinal and choroidal structural changes in central serous chorioretinopathy. bioRxiv.Cold Spring Harbor Laboratory. doi: 10.1101/2023.09.18.557791.

Wang, B., Brown, R., Chhablani, J., & Pi, S. (2023). Volumetrically tracking retinal and choroidal structural changes in central serous chorioretinopathy. Biomed Opt Express, 14(10), 5528-5538.Optica Publishing Group. doi: 10.1364/BOE.506422.

Yam, G.H.F., Pi, S., Du, Y., & Mehta, J.S. (2023). Posterior corneoscleral limbus: Architecture, stem cells, and clinical implications. Prog Retin Eye Res, 96, 101192.Elsevier BV. doi: 10.1016/j.preteyeres.2023.101192.

Pi, S., Hormel, T.T., Wang, B.J., Bailey, S.T., Hwang, T.S., Huang, D., Morrison, J.C., & Jia, Y. (2022). Volume-based, layer-independent, disease-agnostic detection of abnormal retinal reflectivity, nonperfusion, and neovascularization using structural and angiographic OCT. BIOMEDICAL OPTICS EXPRESS, 13(9), 4889-4906.Optica Publishing Group. doi: 10.1364/BOE.469308.

Wei, X., Hormel, T.T., Pi, S., Wang, B., Morrison, J.C., & Jia, Y. (2022). Wide-field sensorless adaptive optics swept-source optical coherence tomographic angiography in rodents. OPTICS LETTERS, 47(19), 5060-5063.Optica Publishing Group. doi: 10.1364/OL.472387.

Pi, S., Hormel, T.T., Wei, X., Cepurna, W., Morrison, J.C., & Jia, Y. (2020). Imaging retinal structures at cellular-level resolution by visible-light optical coherence tomography. OPTICS LETTERS, 45(7), 2107-2110.Optica Publishing Group. doi: 10.1364/OL.386454.

Pi, S., Hormel, T.T., Wei, X., Cepurna, W., Wang, B., Morrison, J.C., & Jia, Y. (2020). Retinal capillary oximetry with visible light optical coherence tomography. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 117(21), 11658-11666.Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.1918546117.

You, Q.S., Wang, J., Guo, Y., Pi, S., Flaxel, C.J., Bailey, S.T., Huang, D., Jia, Y., & Hwang, T.S. (2020). Optical Coherence Tomography Angiography Avascular Area Association With 1-Year Treatment Requirement and Disease Progression in Diabetic Retinopathy. AMERICAN JOURNAL OF OPHTHALMOLOGY, 217, 268-277.Elsevier BV. doi: 10.1016/j.ajo.2020.04.024.

Pi, S., Camino, A., Wei, X., Hormel, T.T., Cepurna, W., Morrison, J.C., & Jia, Y. (2019). Automated phase unwrapping in Doppler optical coherence tomography. JOURNAL OF BIOMEDICAL OPTICS, 24(1), 1-4.SPIE-Intl Soc Optical Eng. doi: 10.1117/1.JBO.24.1.010502.

Pi, S., Hormel, T.T., Wei, X., Cepurna, W., Camino, A., Guo, Y., Huang, D., Morrison, J., & Jia, Y. (2019). Monitoring retinal responses to acute intraocular pressure elevation in rats with visible light optical coherence tomography. NEUROPHOTONICS, 6(4), 041104.SPIE-Intl Soc Optical Eng. doi: 10.1117/1.NPh.6.4.041104.

Wang, B., Camino, A., Pi, S., Guo, Y., Wang, J., Huang, D., Hwang, T.S., & Jia, Y. (2019). Three-dimensional structural and angiographic evaluation of foveal ischemia in diabetic retinopathy: method and validation. BIOMEDICAL OPTICS EXPRESS, 10(7), 3522-3532.The Optical Society. doi: 10.1364/BOE.10.003522.

Wei, X., Camino, A., Pi, S., Hormel, T.T., Cepurna, W., Huang, D., Morrison, J.C., & Jia, Y. (2019). Real-time cross-sectional and en face OCT angiography guiding high-quality scan acquisition. OPTICS LETTERS, 44(6), 1431-1434.The Optical Society. doi: 10.1364/OL.44.001431.

Wei, X., Hormel, T.T., Pi, S., Guo, Y., Jian, Y., & Jia, Y. (2019). High dynamic range optical coherence tomography angiography (HDR-OCTA). BIOMEDICAL OPTICS EXPRESS, 10(7), 3560-3571.The Optical Society. doi: 10.1364/BOE.10.003560.

Pi, S., Camino, A., Cepurna, W., Wei, X., Zhang, M., Huang, D., Morrison, J., & Jia, Y. (2018). Automated spectroscopic retinal oximetry with visible-light optical coherence tomography. BIOMEDICAL OPTICS EXPRESS, 9(5), 2056-2067.The Optical Society. doi: 10.1364/BOE.9.002056.

Pi, S., Camino, A., Wei, X., Simonett, J., Cepurna, W., Huang, D., Morrison, J.C., & Jia, Y. (2018). Rodent retinal circulation organization and oxygen metabolism revealed by visible-light optical coherence tomography. BIOMEDICAL OPTICS EXPRESS, 9(11), 5851-5862.Optica Publishing Group. doi: 10.1364/BOE.9.005851.

Wei, X., Camino, A., Pi, S., Cepurna, W., Huang, D., Morrison, J.C., & Jia, Y. (2018). Fast and robust standard-deviation-based method for bulk motion compensation in phase-based functional OCT. OPTICS LETTERS, 43(9), 2204-2207.The Optical Society. doi: 10.1364/OL.43.002204.

Pi, S., Camino, A., Zhang, M., Cepurna, W., Liu, G., Huang, D., Morrison, J., & Jia, Y. (2017). Angiographic and structural imaging using high axial resolution fiber-based visible-light OCT. BIOMEDICAL OPTICS EXPRESS, 8(10), 4595-4608.The Optical Society. doi: 10.1364/BOE.8.004595.

Pi, S., Wang, B., Zhao, J., & Sun, Q. (2016). High-spatial-resolution localization algorithm based on cascade deconvolution in a distributed Sagnac interferometer invasion monitoring system. APPLIED OPTICS, 55(29), 8180-8184.Optica Publishing Group. doi: 10.1364/AO.55.008180.

Pi, S., Zeng, X., Zhang, N., Ji, D., Chen, B., Song, H., Cheney, A., Xu, Y., Jiang, S., Sun, D., Song, Y., & Gan, Q. (2016). Dielectric-Grating-Coupled Surface Plasmon Resonance From the Back Side of the Metal Film for Ultrasensitive Sensing. IEEE PHOTONICS JOURNAL, 8(1), 1-7.Institute of Electrical and Electronics Engineers (IEEE). doi: 10.1109/JPHOT.2015.2509870.

Shao-Hua, P., Bing-Jie, W., Dong, Z., & Bo, J. (2016). Multi-resolution intrusion localization algorithm through cepstrum in distributed fiber optic Sagnac interferometer. ACTA PHYSICA SINICA, 65(4), 044210.Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences. doi: 10.7498/aps.65.044210.

Zhao, J., Pi, S., Wang, B., & Wu, H. (2016). Harmonic peak locations based on the twice fast Fourier transform algorithm in a Sagnac intrusion sensing system. APPLIED OPTICS, 55(10), 2675-2680.The Optical Society. doi: 10.1364/AO.55.002675.

Pi, S., Wang, B., Jia, B., Sun, Q., Xiao, Q., & Zhao, D. (2015). Intrusion localization algorithm based on linear spectrum in distributed Sagnac optical fiber sensing system. OPTICAL ENGINEERING, 54(8), 085105.SPIE-Intl Soc Optical Eng. doi: 10.1117/1.OE.54.8.085105.

Wang, B., Pi, S., Jia, B., Sun, Q., & Zhao, D. (2015). LOCATION PERFORMANCE FADING FOR MULTIPLE DISTURBANCES IN DISTRIBUTED SAGNAC OPTICAL FIBER INTERFEROMETER. MICROWAVE AND OPTICAL TECHNOLOGY LETTERS, 57(10), 2294-2298.Wiley. doi: 10.1002/mop.29308.

Wang, B., Pi, S., Sun, Q., & Jia, B. (2015). Improved wavelet packet classification algorithm for vibrational intrusions in distributed fiber-optic monitoring systems. OPTICAL ENGINEERING, 54(5), 055104.SPIE-Intl Soc Optical Eng. doi: 10.1117/1.OE.54.5.055104.

Pi, S., Wang, B., Khandaker, I., Brown, R., Flohr, K., & da Silva, S. (2023). Imaging Human Retinal Organoid with Visible Light OCT. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 64(9).