Franca Cambi

  • Chen, K., Cambi, F., & Kozai, T.D.Y. (2023). Pro-myelinating Clemastine administration improves recording performance of chronically implanted microelectrodes and nearby neuronal health. bioRxiv, 2023.01.31.526463.Cold Spring Harbor Laboratory. doi: 10.1101/2023.01.31.526463.
  • Klimas, A., Gallagher, B.R., Wijesekara, P., Fekir, S., DiBernardo, E.F., Cheng, Z., Stolz, D.B., Cambi, F., Watkins, S.C., Brody, S.L., Horani, A., Barth, A.L., Moore, C.I., Ren, X., & Zhao, Y. (2023). Magnify is a universal molecular anchoring strategy for expansion microscopy. Nat Biotechnol, 41(6), 858-869.Springer Nature. doi: 10.1038/s41587-022-01546-1.
  • Song, S., Hasan, M.N., Yu, L., Paruchuri, S.S., Bielanin, J.P., Metwally, S., Oft, H.C.M., Fischer, S.G., Fiesler, V.M., Sen, T., Gupta, R.K., Foley, L.M., Hitchens, T.K., Dixon, C.E., Cambi, F., Sen, N., & Sun, D. (2022). Microglial-oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury. J Neuroinflammation, 19(1), 246.Springer Nature. doi: 10.1186/s12974-022-02608-6.
  • Dubaniewicz, M., Eles, J.R., Lam, S., Song, S., Cambi, F., Sun, D., Wellman, S.M., & Kozai, T.D.Y. (2021). Inhibition of Na+/H+exchanger modulates microglial activation and scar formation following microelectrode implantation. J Neural Eng, 18(4).IOP Publishing. doi: 10.1088/1741-2552/abe8f1.
  • Zhang, S., Wang, Y., Zhu, X., Song, L., Zhan, X., Ma, E., McDonough, J., Fu, H., Cambi, F., Grinspan, J., & Guo, F. (2021). The Wnt Effector TCF7l2 Promotes Oligodendroglial Differentiation by Repressing Autocrine BMP4-Mediated Signaling. J Neurosci, 41(8), 1650-1664.Society for Neuroscience. doi: 10.1523/JNEUROSCI.2386-20.2021.
  • Guzman, K.M., Brink, L.E., Rodriguez-Bey, G., Bodnar, R.J., Kuang, L., Xing, B., Sullivan, M., Park, H.J., Koppes, E., Zhu, H., Padiath, Q., & Cambi, F. (2020). Conditional depletion of Fus in oligodendrocytes leads to motor hyperactivity and increased myelin deposition associated with Akt and cholesterol activation. Glia, 68(10), 2040-2056.Wiley. doi: 10.1002/glia.23825.
  • Su, X.W., Palka, S.V., Rao, R.R., Chen, F.S., Brackney, C.R., & Cambi, F. (2020). SARS-CoV-2-associated Guillain-Barré syndrome with dysautonomia. Muscle Nerve, 62(2), E48-E49.Wiley. doi: 10.1002/mus.26988.
  • Wellman, S.M., Guzman, K., Stieger, K.C., Brink, L.E., Sridhar, S., Dubaniewicz, M.T., Li, L., Cambi, F., & Kozai, T.D.Y. (2020). Cuprizone-induced oligodendrocyte loss and demyelination impairs recording performance of chronically implanted neural interfaces. Biomaterials, 239, 119842.Elsevier. doi: 10.1016/j.biomaterials.2020.119842.
  • Espay, A.J., Vizcarra, J.A., Marsili, L., Lang, A.E., Simon, D.K., Merola, A., Josephs, K.A., Fasano, A., Morgante, F., Savica, R., Greenamyre, J.T., Cambi, F., Yamasaki, T.R., Tanner, C.M., Gan-Or, Z., Litvan, I., Mata, I.F., Zabetian, C.P., Brundin, P., Fernandez, H.H., Standaert, D.G., Kauffman, M.A., Schwarzschild, M.A., Sardi, S.P., Sherer, T., Perry, G., & Leverenz, J.B. (2019). Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases. Neurology, 92(7), 329-337.Wolters Kluwer. doi: 10.1212/WNL.0000000000006926.
  • Wellman, S.M., Cambi, F., & Kozai, T.D. (2018). The role of oligodendrocytes and their progenitors on neural interface technology: A novel perspective on tissue regeneration and repair. Biomaterials, 183, 200-217.Elsevier. doi: 10.1016/j.biomaterials.2018.08.046.
  • Xing, B., Brink, L.E., Maers, K., Sullivan, M.L., Bodnar, R.J., Stolz, D.B., & Cambi, F. (2018). Conditional depletion of GSK3b protects oligodendrocytes from apoptosis and lessens demyelination in the acute cuprizone model. Glia, 66(9), 1999-2012.Wiley. doi: 10.1002/glia.23453.
  • Leehey, M., Luo, S., Sharma, S., Wills, A.M.A., Bainbridge, J.L., Wong, P.S., Simon, D.K., Schneider, J., Zhang, Y., Pérez, A., Dhall, R., Christine, C.W., Singer, C., Cambi, F., & Boyd, J.T. (2017). Association of metabolic syndrome and change in Unified Parkinson's Disease Rating Scale scores. Neurology, 89(17), 1789-1794.Wolters Kluwer. doi: 10.1212/WNL.0000000000004572.
  • Kapeli, K., Pratt, G.A., Vu, A.Q., Hutt, K.R., Martinez, F.J., Sundararaman, B., Batra, R., Freese, P., Lambert, N.J., Huelga, S.C., Chun, S.J., Liang, T.Y., Chang, J., Donohue, J.P., Shiue, L., Zhang, J., Zhu, H., Cambi, F., Kasarskis, E., Hoon, S., Ares, M., Burge, C.B., Ravits, J., Rigo, F., & Yeo, G.W. (2016). Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses. Nat Commun, 7(1), 12143.Springer Nature. doi: 10.1038/ncomms12143.
  • NINDS Exploratory Trials in Parkinson Disease (NET-PD) FS-ZONE Investigators. (2015). Pioglitazone in early Parkinson's disease: a phase 2, multicentre, double-blind, randomised trial. Lancet Neurol, 14(8), 795-803.Elsevier. doi: 10.1016/S1474-4422(15)00144-1.
  • Schneider, J.S., Cambi, F., Gollomp, S.M., Kuwabara, H., Brašić, J.R., Leiby, B., Sendek, S., & Wong, D.F. (2015). GM1 ganglioside in Parkinson's disease: Pilot study of effects on dopamine transporter binding. J Neurol Sci, 356(1-2), 118-123.Elsevier. doi: 10.1016/j.jns.2015.06.028.
  • Elm, J.J., & NINDS NET-PD Investigators. (2012). Design innovations and baseline findings in a long-term Parkinson's trial: the National Institute of Neurological Disorders and Stroke Exploratory Trials in Parkinson's Disease Long-Term Study-1. Mov Disord, 27(12), 1513-1521.Wiley. doi: 10.1002/mds.25175.
  • Goldman, S.M., Quinlan, P.J., Ross, G.W., Marras, C., Meng, C., Bhudhikanok, G.S., Comyns, K., Korell, M., Chade, A.R., Kasten, M., Priestley, B., Chou, K.L., Fernandez, H.H., Cambi, F., Langston, J.W., & Tanner, C.M. (2012). Solvent exposures and Parkinson disease risk in twins. Ann Neurol, 71(6), 776-784.Wiley. doi: 10.1002/ana.22629.
  • Magen, S., Magnani, R., Haziza, S., Hershkovitz, E., Houtz, R., Cambi, F., & Parvari, R. (2012). Human calmodulin methyltransferase: expression, activity on calmodulin, and Hsp90 dependence. In Strack, S. (Ed.). PLoS One, 7(12), e52425.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0052425.
  • Wang, E., & Cambi, F. (2012). MicroRNA expression in mouse oligodendrocytes and regulation of proteolipid protein gene expression. J Neurosci Res, 90(9), 1701-1712.Wiley. doi: 10.1002/jnr.23055.
  • Wang, E., Aslanzadeh, V., Papa, F., Zhu, H., de la Grange, P., & Cambi, F. (2012). Global profiling of alternative splicing events and gene expression regulated by hnRNPH/F. In Xing, Y. (Ed.). PLoS One, 7(12), e51266.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0051266.
  • Zhu, H., Zhao, L., Wang, E., Dimova, N., Liu, G., Feng, Y., & Cambi, F. (2012). The QKI-PLP pathway controls SIRT2 abundance in CNS myelin. Glia, 60(1), 69-82.Wiley. doi: 10.1002/glia.21248.
  • Tanner, C.M., Kamel, F., Ross, G.W., Hoppin, J.A., Goldman, S.M., Korell, M., Marras, C., Bhudhikanok, G.S., Kasten, M., Chade, A.R., Comyns, K., Richards, M.B., Meng, C., Priestley, B., Fernandez, H.H., Cambi, F., Umbach, D.M., Blair, A., Sandler, D.P., & Langston, J.W. (2011). Rotenone, paraquat, and Parkinson's disease. Environ Health Perspect, 119(6), 866-872.American Chemical Society (ACS). doi: 10.1289/ehp.1002839.
  • Wang, E., Mueller, W.F., Hertel, K.J., & Cambi, F. (2011). G Run-mediated recognition of proteolipid protein and DM20 5' splice sites by U1 small nuclear RNA is regulated by context and proximity to the splice site. J Biol Chem, 286(6), 4059-4071.Elsevier. doi: 10.1074/jbc.M110.199927.
  • Bargagna-Mohan, P., Paranthan, R.R., Hamza, A., Dimova, N., Trucchi, B., Srinivasan, C., Elliott, G.I., Zhan, C.G., Lau, D.L., Zhu, H., Kasahara, K., Inagaki, M., Cambi, F., & Mohan, R. (2010). Withaferin A targets intermediate filaments glial fibrillary acidic protein and vimentin in a model of retinal gliosis. J Biol Chem, 285(10), 7657-7669.Elsevier. doi: 10.1074/jbc.M109.093765.
  • Schneider, J.S., Sendek, S., Daskalakis, C., & Cambi, F. (2010). GM1 ganglioside in Parkinson's disease: Results of a five year open study. J Neurol Sci, 292(1-2), 45-51.Elsevier. doi: 10.1016/j.jns.2010.02.009.
  • Wang, E., & Cambi, F. (2009). Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs. J Biol Chem, 284(17), 11194-11204.Elsevier. doi: 10.1074/jbc.M809373200.
  • DeStefano, A.L., Latourelle, J., Lew, M.F., Suchowersky, O., Klein, C., Golbe, L.I., Mark, M.H., Growdon, J.H., Wooten, G.F., Watts, R., Guttman, M., Racette, B.A., Perlmutter, J.S., Marlor, L., Shill, H.A., Singer, C., Goldwurm, S., Pezzoli, G., Saint-Hilaire, M.H., Hendricks, A.E., Gower, A., Williamson, S., Nagle, M.W., Wilk, J.B., Massood, T., Huskey, K.W., Baker, K.B., Itin, I., Litvan, I., Nicholson, G., Corbett, A., Nance, M., Drasby, E., Isaacson, S., Burn, D.J., Chinnery, P.F., Pramstaller, P.P., Al-Hinti, J., Moller, A.T., Ostergaard, K., Sherman, S.J., Roxburgh, R., Snow, B., Slevin, J.T., Cambi, F., Gusella, J.F., & Myers, R.H. (2008). Replication of association between ELAVL4 and Parkinson disease: the GenePD study. Hum Genet, 124(1), 95-99.Springer Nature. doi: 10.1007/s00439-008-0526-4.
  • Latourelle, J.C., Sun, M., Lew, M.F., Suchowersky, O., Klein, C., Golbe, L.I., Mark, M.H., Growdon, J.H., Wooten, G.F., Watts, R.L., Guttman, M., Racette, B.A., Perlmutter, J.S., Ahmed, A., Shill, H.A., Singer, C., Goldwurm, S., Pezzoli, G., Zini, M., Saint-Hilaire, M.H., Hendricks, A.E., Williamson, S., Nagle, M.W., Wilk, J.B., Massood, T., Huskey, K.W., Laramie, J.M., DeStefano, A.L., Baker, K.B., Itin, I., Litvan, I., Nicholson, G., Corbett, A., Nance, M., Drasby, E., Isaacson, S., Burn, D.J., Chinnery, P.F., Pramstaller, P.P., Al-hinti, J., Moller, A.T., Ostergaard, K., Sherman, S.J., Roxburgh, R., Snow, B., Slevin, J.T., Cambi, F., Gusella, J.F., & Myers, R.H. (2008). The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study. BMC Med, 6(1), 32.Springer Nature. doi: 10.1186/1741-7015-6-32.
  • McNicoll, C.F., Latourelle, J.C., MacDonald, M.E., Lew, M.F., Suchowersky, O., Klein, C., Golbe, L.I., Mark, M.H., Growdon, J.H., Wooten, G.F., Watts, R.L., Guttman, M., Racette, B.A., Perlmutter, J.S., Ahmed, A., Shill, H.A., Singer, C., Saint-Hilaire, M.H., Massood, T., Huskey, K.W., DeStefano, A.L., Gillis, T., Mysore, J., Goldwurm, S., Pezzoli, G., Baker, K.B., Itin, I., Litvan, I., Nicholson, G., Corbett, A., Nance, M., Drasby, E., Isaacson, S., Burn, D.J., Chinnery, P.F., Pramstaller, P.P., Al-Hinti, J., Moller, A.T., Ostergaard, K., Sherman, S.J., Roxburgh, R., Snow, B., Slevin, J.T., Cambi, F., Gusella, J.F., & Myers, R.H. (2008). Huntington CAG repeat size does not modify onset age in familial Parkinson's disease: the GenePD study. Mov Disord, 23(11), 1596-1601.Wiley. doi: 10.1002/mds.22186.
  • Tobin, J.E., Latourelle, J.C., Lew, M.F., Klein, C., Suchowersky, O., Shill, H.A., Golbe, L.I., Mark, M.H., Growdon, J.H., Wooten, G.F., Racette, B.A., Perlmutter, J.S., Watts, R., Guttman, M., Baker, K.B., Goldwurm, S., Pezzoli, G., Singer, C., Saint-Hilaire, M.H., Hendricks, A.E., Williamson, S., Nagle, M.W., Wilk, J.B., Massood, T., Laramie, J.M., DeStefano, A.L., Litvan, I., Nicholson, G., Corbett, A., Isaacson, S., Burn, D.J., Chinnery, P.F., Pramstaller, P.P., Sherman, S., Al-hinti, J., Drasby, E., Nance, M., Moller, A.T., Ostergaard, K., Roxburgh, R., Snow, B., Slevin, J.T., Cambi, F., Gusella, J.F., & Myers, R.H. (2008). Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study. Neurology, 71(1), 28-34.Wolters Kluwer. doi: 10.1212/01.wnl.0000304051.01650.23.
  • Wang, E., Dimova, N., Sperle, K., Huang, Z., Lock, L., McCulloch, M.C., Edgar, J.M., Hobson, G.M., & Cambi, F. (2008). Deletion of a splicing enhancer disrupts PLP1/DM20 ratio and myelin stability. Exp Neurol, 214(2), 322-330.Elsevier. doi: 10.1016/j.expneurol.2008.09.001.
  • Squillaro, T., Cambi, F., Ciacci, G., Rossi, S., Ulivelli, M., Malandrini, A., Mencarelli, M.A., Mari, F., Renieri, A., & Ariani, F. (2007). Frequency of the LRRK2 G2019S mutation in Italian patients affected by Parkinson's disease. J Hum Genet, 52(3), 201-204.Springer Nature. doi: 10.1007/s10038-006-0105-2.
  • Wang, E., Dimova, N., & Cambi, F. (2007). PLP/DM20 ratio is regulated by hnRNPH and F and a novel G-rich enhancer in oligodendrocytes. Nucleic Acids Res, 35(12), 4164-4178.Oxford University Press (OUP). doi: 10.1093/nar/gkm387.
  • Hobson, G.M., Huang, Z., Sperle, K., Sistermans, E., Rogan, P.K., Garbern, J.Y., Kolodny, E., Naidu, S., & Cambi, F. (2006). Splice-site contribution in alternative splicing of PLP1 and DM20: molecular studies in oligodendrocytes. Hum Mutat, 27(1), 69-77.Hindawi. doi: 10.1002/humu.20276.
  • Sabet, A., Li, J., Ghandour, K., Pu, Q., Wu, X., Kamholz, J., Shy, M.E., & Cambi, F. (2006). Skin biopsies demonstrate MPZ splicing abnormalities in Charcot-Marie-Tooth neuropathy 1B. Neurology, 67(7), 1141-1146.Wolters Kluwer. doi: 10.1212/01.wnl.0000238499.37764.b1.
  • Wang, E., Huang, Z., Hobson, G.M., Dimova, N., Sperle, K., McCullough, A., & Cambi, F. (2006). PLP1 alternative splicing in differentiating oligodendrocytes: characterization of an exonic splicing enhancer. J Cell Biochem, 97(5), 999-1016.Wiley. doi: 10.1002/jcb.20692.
  • Wilk, J.B., Tobin, J.E., Suchowersky, O., Shill, H.A., Klein, C., Wooten, G.F., Lew, M.F., Mark, M.H., Guttman, M., Watts, R.L., Singer, C., Growdon, J.H., Latourelle, J.C., Saint-Hilaire, M.H., DeStefano, A.L., Prakash, R., Williamson, S., Berg, C.J., Sun, M., Goldwurm, S., Pezzoli, G., Racette, B.A., Perlmutter, J.S., Parsian, A., Baker, K.B., Giroux, M.L., Litvan, I., Pramstaller, P.P., Nicholson, G., Burn, D.J., Chinnery, P.F., Vieregge, P., Slevin, J.T., Cambi, F., MacDonald, M.E., Gusella, J.F., Myers, R.H., & Golbe, L.I. (2006). Herbicide exposure modifies GSTP1 haplotype association to Parkinson onset age: the GenePD Study. Neurology, 67(12), 2206-2210.Wolters Kluwer. doi: 10.1212/01.wnl.0000249149.22407.d1.
  • Mari, F., Kilstrup-Nielsen, C., Cambi, F., Speciale, C., Mencarelli, M.A., & Renieri, A. (2005). Genetics and mechanisms of disease in Rett syndrome. Drug Discovery Today Disease Mechanisms, 2(4), 419-425.Elsevier. doi: 10.1016/j.ddmec.2005.11.001.
  • Garbern, J., Shy, M., Krajewski, K., Kamholz, J., Hobson, G., & Cambi, F. (2001). Evidence for neuroaxonal injury in patients with proteolipid gene mutations. Neurology, 57(10), 1938-1939.Wolters Kluwer. doi: 10.1212/wnl.57.10.1938-a.
  • Mars, T., Yu, K.J., Tang, X.M., Miranda, A.F., Grubic, Z., Cambi, F., & King, M.P. (2001). Differentiation of glial cells and motor neurons during the formation of neuromuscular junctions in cocultures of rat spinal cord explant and human muscle. J Comp Neurol, 438(2), 239-251.Wiley. doi: 10.1002/cne.1312.
  • Awatramani, R., Beesley, J., Yang, H., Jiang, H., Cambi, F., Grinspan, J., Garbern, J., & Kamholz, J. (2000). Gtx, an oligondendrocyte-specific homeodomain protein, has repressor activity. Journal of Neuroscience Research, 61(4), 376-387. doi: 10.1002/1097-4547(20000815)61:4<376::aid-jnr4>3.0.co;2-%23.
  • Awatramani, R., Beesley, J., Yang, H., Jiang, H., Cambi, F., Grinspan, J., Garbern, J., & Kamholz, J. (2000). Gtx, an oligodendrocyte-specific homeodomain protein, has repressor activity. J Neurosci Res, 61(4), 376-387.Wiley. doi: 10.1002/1097-4547(20000815)61:4<376::AID-JNR4>3.0.CO;2-#.
  • Hentati, A., Deng, H.X., Zhai, H., Chen, W., Yang, Y., Hung, W.Y., Azim, A.C., Bohlega, S., Tandan, R., Warner, C., Laing, N.G., Cambi, F., Mitsumoto, H., Roos, R.P., Boustany, R.M., Ben Hamida, M., Hentati, F., & Siddique, T. (2000). Novel mutations in spastin gene and absence of correlation with age at onset of symptoms. Neurology, 55(9), 1388-1390.Wolters Kluwer. doi: 10.1212/wnl.55.9.1388.
  • Tang, X.M., Beesley, J.S., Grinspan, J.B., Seth, P., Kamholz, J., & Cambi, F. (2000). Cell cycle arrest induced by ectopic expression of p27 is not sufficient to promote oligodendrocyte differentiation. Journal of Cellular Biochemistry, 76(2), 270-279. doi: 10.1002/(SICI)1097-4644(20000201)76:2<270::AID-JCB10>3.0.CO;2-6.
  • Garbern, J., Cambi, F., Shy, M., & Kamholz, J. (1999). The molecular pathogenesis of Pelizaeus-Merzbacher disease. Arch Neurol, 56(10), 1210-1214.American Medical Association (AMA). doi: 10.1001/archneur.56.10.1210.
  • Garbern, J.Y., Cambi, F., Lewis, R., Shy, M., Sima, A., Kraft, G., Vallat, J.M., Bosch, E.P., Hodes, M.E., Dlouhy, S., Raskind, W., Bird, T., Macklin, W., & Kamholz, J. (1999). Peripheral neuropathy caused by proteolipid protein gene mutations. Ann N Y Acad Sci, 883(1), 351-365.Wiley. doi: 10.1111/j.1749-6632.1999.tb08597.x.
  • Tang, X.M., Beesley, J.S., Grinspan, J.B., Seth, P., Kamholz, J., & Cambi, F. (1999). Cell cycle arrest induced by ectopic expression of p27 is not sufficient to promote oligodendrocyte differentiation. J Cell Biochem, 76(2), 270-279.Wiley. doi: 10.1002/(sici)1097-4644(20000201)76:2<270::aid-jcb10>3.0.co;2-6.
  • Tang, X.M., Strocchi, P., & Cambi, F. (1998). Changes in the activity of cdk2 and cdk5 accompany differentiation of rat primary oligodendrocytes. J Cell Biochem, 68(1), 128-137.Wiley. doi: 10.1002/(sici)1097-4644(19980101)68:1<128::aid-jcb13>3.0.co;2-d.
  • Tang, X.M., Strocchi, P., & Cambi, F. (1998). Changes in the activity of cdk2 and cdk5 accompany differentiation of rat primary oligodendrocytes. Journal of Cellular Biochemistry, 68(1), 128-137. doi: 10.1002/(SICI)1097-4644(19980101)68:1<128::AID-JCB13>3.0.CO;2-D.
  • Berghella, V., Steele, D., Spector, T., Cambi, F., & Johnson, A. (1997). Successful pregnancy in a neurologically impaired woman with Wilson's disease. Am J Obstet Gynecol, 176(3), 712-714.Elsevier. doi: 10.1016/s0002-9378(97)70577-5.
  • Garbern, J.Y., Cambi, F., Tang, X.M., Sima, A.A., Vallat, J.M., Bosch, E.P., Lewis, R., Shy, M., Sohi, J., Kraft, G., Chen, K.L., Joshi, I., Leonard, D.G., Johnson, W., Raskind, W., Dlouhy, S.R., Pratt, V., Hodes, M.E., Bird, T., & Kamholz, J. (1997). Proteolipid protein is necessary in peripheral as well as central myelin. Neuron, 19(1), 205-218.Elsevier. doi: 10.1016/s0896-6273(00)80360-8.
  • Cambi, F., Tang, X.M., Cordray, P., Fain, P.R., Keppen, L.D., & Barker, D.F. (1996). Refined genetic mapping and proteolipid protein mutation analysis in X-linked pure hereditary spastic paraplegia. Neurology, 46(4), 1112-1117.Wolters Kluwer. doi: 10.1212/wnl.46.4.1112.
  • Fink, J.K., HeimanPatterson, T., Bird, T., Cambi, F., Dube, M.P., Figlewicz, D.A.Fink, J.K., Haines, J.L., HeimanPatterson, T., Hentati, A., PericakVance, M.A., Raskind, W., Rouleau, G.A., & Siddique, T. (1996). Hereditary spastic paraplegia: Advances in genetic research. NEUROLOGY, 46(6), 1507-1514.Ovid Technologies (Wolters Kluwer Health). doi: 10.1212/WNL.46.6.1507.
  • Fink, J.K., Heiman-Patterson, T., Bird, T., Cambi, F., Dubé, M.P., Figlewicz, D.A.Fink, J.K., Haines, J.L., Heiman-Patterson, T., Hentati, A., Pericak-Vance, M.A., Raskind, W., Rouleau, G.A., & Siddique, T. (1996). Hereditary spastic paraplegia: advances in genetic research. Hereditary Spastic Paraplegia Working group. Neurology, 46(6), 1507-1514.Wolters Kluwer. doi: 10.1212/wnl.46.6.1507.
  • Cambi, F., Tartaglino, L., Lublin, F., & McCarren, D. (1995). X-linked pure familial spastic paraparesis. Characterization of a large kindred with magnetic resonance imaging studies. Arch Neurol, 52(7), 665-669.American Medical Association (AMA). doi: 10.1001/archneur.1995.00540310035013.
  • Strocchi, P., Tang, X.M., & Cambi, F. (1995). Molecular diagnosis of transthyretin Met30 mutation in an Italian family with familial amyloidotic polyneuropathy. FEBS Lett, 359(2-3), 203-205.Wiley. doi: 10.1016/0014-5793(95)00046-c.

  • Hasan, M.N., Song, S., Paruchuri, S.S., Bielanin, J.P., Metwally, S., Sen, T., Gupta, R.K., Dixon, E., Cambi, F., Sen, N., & Sun, D. (2022). NA plus /H plus EXCHANGER IN INFLAMMATORY ACTIVATION OF MICROGLIA/MYELOID CELLS AND TRAUMATIC BRAIN INJURY OUTCOMES. In JOURNAL OF NEUROTRAUMA, 39(11-12), (pp. A29-A30).
  • Paruchuri, S.S., Song, S., Hasan, N., Bielanin, J.P., Metwally, S., Sen, T., Gupta, R.K., Dixon, C.E., Cambi, F., Sen, N., & Sun, D. (2022). SODIUM-HYDROGEN EXCHANGER (NHE1) AS A THERAPEUTIC TARGET FOR TRAUMATIC BRAIN INJURY. In JOURNAL OF NEUROTRAUMA, 39(11-12), (p. A63).
  • Palka, S., Su, X., & Cambi, F. (2021). SARS-CoV-2 Associated Guillain-Barre Syndrome with Dysautonomia. In NEUROLOGY, 96(15).
  • Song, S., Yu, L., Sen, T., Hasan, N., Gupta, R.K., Maers, K., Li, E., Cambi, F., Sen, N., & Sun, D. (2021). ROLES OF MICROGLIAL NA/H EXCHANGER IN WHITE MATTER DAMAGE AND NEUROLOGICAL DYSFUNCTION AFTER TRAUMATIC BRAIN INJURY. In JOURNAL OF NEUROTRAUMA, 38(14), (pp. A104-A105).
  • Song, S., Gupta, R., Yu, L., Maers, K., Li, E., Cambi, F., Sen, N., & Sun, D. (2019). RESTORATIVE MICROGLIA-OLIGODENDROCYTE INTERACTIONS IN POST-TBI REMYELINATION. In JOURNAL OF NEUROTRAUMA, 36(13), (p. A127).
  • Spears, C.C., Soneji, D., & Cambi, F. (2017). Fatal VZV Myelitis In Association With Chronic Corticosteroid and Mycophenolate Mofetil Therapy. In NEUROLOGY, 88.
  • Schneider, J.S., Sendek, S., Gollomp, S.M., Colcher, A., Cambi, F., & Du, W. (2011). A delayed start trial of GM1 ganglioside in Parkinson's disease. In MOVEMENT DISORDERS, 26, (p. S139).
  • Tanner, C.M., Kamel, F., Ross, G.W., Hoppin, J.A., Goldman, S.M., Korell, M., Marras, C., Bhudhikanok, G.S., Kasten, M., Chade, A., Comyns, K., Meng, C., Priestley, B., Fernandez, H.H., Cambi, F., Umbach, D.M., Blair, A., Sandler, D.P., & Langston, J.W. (2010). Rotenone, Paraquat and Parkinson's Disease (PD). In ANNALS OF NEUROLOGY, 68(4), (p. S17).
  • Wang, E., Dimova, N., Sperle, K., Lock, L., Hobson, G., & Cambi, F. (2008). Deletion of an intronic splicing enhancer impairs PLP1 splicing and myelin stability in vivo. In ANNALS OF NEUROLOGY, 64, (p. S35).
  • Cambi, F., Sperle, K., Huang, Z., Garbern, J., Rogan, P., & Hobson, G. (2006). Is PLP necessary for brain development and function? 'the human perspective'. In JOURNAL OF NEUROCHEMISTRY, 96, (p. 12).
  • Cambi, F., Hodes, M.E., Barker, D.F., Parrott, J., & Dlouhy, S.R. (2001). The same mutation in exon 5 of the proteolipid protein gene causes Pelizaeus-Merzbacher disease in one kindred and pure X-linked spastic paraplegia in an apparently unrelated family with a similar haplotype. In NEUROLOGY, 56(8), (p. A134).
  • Hobson, G.M., Huang, Z., MacCullough, A., Marks, H.G., Stabley, D., Sperle, K., & Cambi, F. (2001). Abnormal processing of proteolipid protein pre-mRNA is associated with an unusual Pelizaeus-Merzbacher disease. In AMERICAN JOURNAL OF HUMAN GENETICS, 69(4), (p. 598).
  • Huang, Z., & Cambi, F. (2001). Lineage progression of rat oligodendrocyte progenitor cells ectopically expressing p21-cip in vitro. In MOLECULAR BIOLOGY OF THE CELL, 12, (p. 10A).
  • Huang, Z., Tang, X.M., & Cambi, F. (2000). Early G1 cell cycle molecules and oligodendrocyte differentiation. In MOLECULAR BIOLOGY OF THE CELL, 11, (p. 451A).
  • Mars, T., King, M.P., Cambi, F., Miranda, A.F., & Grubic, Z. (2000). Agrin-specific antibodies reduce the final number of contracting units in innervated cultures of human muscle but do not abolish early contractions. In EUROPEAN JOURNAL OF NEUROSCIENCE, 12, (p. 281).
  • Cambi, F., Garbern, J., Shy, M., & Kamholz, J. (1999). X-linked spasticity syndromes caused by mutations in the PLP gene. In JOURNAL OF NEUROCHEMISTRY, 72, (p. S17).
  • Ghiani, C.A., Tang, X.M., Cambi, F., & Gallo, V. (1999). Expression and regulation of cyclin dependent kinase 5 in the oligodendrocyte lineage. In MOLECULAR BIOLOGY OF THE CELL, 10, (p. 433A).
  • Tang, X.M., Beesley, J., Grinspan, J., Seth, P., Kamholz, J., & Cambi, F. (1998). Cell cycle arrest induced by p27 is not sufficient to promote oligodendrocyte differentiation. In MOLECULAR BIOLOGY OF THE CELL, 9, (p. 240A).
  • Garbern, J.Y., Cambi, F., Lewis, R., Shy, M.E., Hodes, M.E., Dlouhy, S., Pratt, V., Sima, A., Bird, T., & Kamholz, J. (1997). Proteolipid protein (PLP) expression is critical for PNS as well as CNS myelination: Molecular and pathological characterization of a family with a novel PLP mutation. In NEUROLOGY, 48(3), (p. 6093).
  • Cambi, F., Tang, X.M., & Saitta, S. (1996). CDKs expression during oligodendrocytes differentiation. In MOLECULAR BIOLOGY OF THE CELL, 7, (p. 2125).
  • CAMBI, F., TANG, X.M., CORDRAY, P., FAIN, P.R., KEPPEN, L., & BARKER, D. (1995). LINKAGE OF PURE X-LINKED SPASTIC PARAPLEGIA TO XQ22 IN 2 PEDIGREES. In NEUROLOGY, 45(4), (pp. A439-A440).
Research Interests
Neurosciences Clinical sciences Biochemistry and cell biology Biological psychology Genetics Bioinformatics and computational biology
headshot of Franca Cambi
Contact Franca Cambi
Professor
franca@pitt.edu
Bioengineering Department