PhD, Italian Institute of Technology, 2020 - 2011
Castagnola, E., Cao, Q., Robbins, E., Wu, B., Pwint, M.Y., Siwakoti, U., & Cui, X.T. (2025). Glassy Carbon Fiber-Like Multielectrode Arrays for Neurochemical Sensing and Electrophysiology Recording. ADVANCED MATERIALS TECHNOLOGIES, 10(4).Wiley. doi: 10.1002/admt.202400863.
Siwakoti, U., Jones, S.A., Kumbhare, D., Cui, X.T., & Castagnola, E. (2025). Recent Progress in Flexible Microelectrode Arrays for Combined Electrophysiological and Electrochemical Sensing. Biosensors (Basel), 15(2), 100.MDPI. doi: 10.3390/bios15020100.
Faul, E.B.A., Broussard, A.M., Rivera, D.R., Pwint, M.Y., Wu, B., Cao, Q., Bailey, D., Cui, X.T., & Castagnola, E. (2024). Batch Fabrication of Microelectrode Arrays with Glassy Carbon Microelectrodes and Interconnections for Neurochemical Sensing: Promises and Challenges. Micromachines (Basel), 15(2), 277.MDPI. doi: 10.3390/mi15020277.
Yang, Q., Wu, B., Castagnola, E., Pwint, M.Y., Williams, N.P., Vazquez, A.L., & Cui, X.T. (2024). Integrated Microprism and Microelectrode Array for Simultaneous Electrophysiology and Two-Photon Imaging across All Cortical Layers. Adv Healthc Mater, 13(24), e2302362.Wiley. doi: 10.1002/adhm.202302362.
Castagnola, E., Robbins, E.M., Krahe, D., Wu, B., Pwint, M.Y., Cao, Q., & Cui, X.T. (2023). Implantable flexible multielectrode arrays for multi-site sensing of serotonin tonic levels. bioRxiv, 4(01-27), 2023.01.17.524488.Cold Spring Harbor Laboratory. doi: 10.1101/2023.01.17.524488.
Salavatian, S., Robbins, E.M., Kuwabara, Y., Castagnola, E., Cui, X.T., & Mahajan, A. (2023). Real-time in vivo thoracic spinal glutamate sensing during myocardial ischemia. Am J Physiol Heart Circ Physiol, 325(6), H1304-H1317.American Physiological Society. doi: 10.1152/ajpheart.00299.2023.
Nam, K.H., Abdulhafez, M., Castagnola, E., Tomaraei, G.N., Cui, X.T., & Bedewy, M. (2022). Laser direct write of heteroatom-doped graphene on molecularly controlled polyimides for electrochemical biosensors with nanomolar sensitivity. Carbon N Y, 188, 209-219.Elsevier. doi: 10.1016/j.carbon.2021.10.010.
Castagnola, E., Garg, R., Rastogi, S.K., Cohen-Karni, T., & Cui, X.T. (2021). 3D fuzzy graphene microelectrode array for dopamine sensing at sub-cellular spatial resolution. Biosens Bioelectron, 191, 113440.Elsevier. doi: 10.1016/j.bios.2021.113440.
Castagnola, E., Thongpang, S., Hirabayashi, M., Nava, G., Nimbalkar, S., Nguyen, T., Lara, S., Oyawale, A., Bunnell, J., Moritz, C., & Kassegne, S. (2021). Glassy carbon microelectrode arrays enable voltage-peak separated simultaneous detection of dopamine and serotonin using fast scan cyclic voltammetry. Analyst, 146(12), 3955-3970.Royal Society of Chemistry (RSC). doi: 10.1039/d1an00425e.
Castagnola, V., Castagnola, E., Bergaud, C., & Ricci, D. (2021). Editorial: Short-Term Versus Long-Term Challenges in Functional Biomaterials Interfacing Living Systems: Two Sides of the Coin. Front Bioeng Biotechnol, 9, 723451.Frontiers. doi: 10.3389/fbioe.2021.723451.
Devi, M., Vomero, M., Fuhrer, E., Castagnola, E., Gueli, C., Nimbalkar, S., Hirabayashi, M., Kassegne, S., Stieglitz, T., & Sharma, S. (2021). Carbon-based neural electrodes: promises and challenges. J Neural Eng, 18(4), 041007.IOP Publishing. doi: 10.1088/1741-2552/ac1e45.
Tia, B., Takemi, M., Kosugi, A., Castagnola, E., Ricci, D., Ushiba, J., Fadiga, L., & Iriki, A. (2021). Spectral Power in Marmoset Frontal Motor Cortex during Natural Locomotor Behavior. Cereb Cortex, 31(2), 1077-1089.Oxford University Press (OUP). doi: 10.1093/cercor/bhaa275.
Zheng, X.S., Tan, C., Castagnola, E., & Cui, X.T. (2021). Electrode Materials for Chronic Electrical Microstimulation. Adv Healthc Mater, 10(12), e2100119.Wiley. doi: 10.1002/adhm.202100119.
Castagnola, E., Robbins, E.M., Woeppel, K.M., McGuier, M., Golabchi, A., Taylor, I.M., Michael, A.C., & Cui, X.T. (2020). Real-Time Fast Scan Cyclic Voltammetry Detection and Quantification of Exogenously Administered Melatonin in Mice Brain. Front Bioeng Biotechnol, 8, 602216.Frontiers. doi: 10.3389/fbioe.2020.602216.
Castagnola, E., Woeppel, K., Golabchi, A., McGuier, M., Chodapaneedi, N., Metro, J., Taylor, I.M., & Cui, X.T. (2020). Electrochemical detection of exogenously administered melatonin in the brain. Analyst, 145(7), 2612-2620.Royal Society of Chemistry (RSC). doi: 10.1039/d0an00051e.
Vahidi, N.W., Rudraraju, S., Castagnola, E., Cea, C., Nimbalkar, S., Hanna, R., Arvizu, R., Dayeh, S.A., Gentner, T.Q., & Kassegne, S. (2020). Epi-Intra neural probes with glassy carbon microelectrodes help elucidate neural coding and stimulus encoding in 3D volume of tissue. J Neural Eng, 17(4), 046005.IOP Publishing. doi: 10.1088/1741-2552/ab9b5c.
Kosugi, A., Castagnola, E., Carli, S., Ricci, D., Fadiga, L., Taoka, M., Iriki, A., & Ushiba, J. (2019). Fast Electrophysiological Mapping of Rat Cortical Motor Representation on a Time Scale of Minutes during Skin Stimulation. Neuroscience, 414, 245-254.Elsevier. doi: 10.1016/j.neuroscience.2019.07.011.
Kosugi, A., Castagnola, E., Carli, S., Ricci, D., Fadiga, L., Taoka, M., Iriki, A., & Ushiba, J. (2019). Erratum to 'Fast Electrophysiological Mapping of Rat Cortical Motor Representation on a Time Scale of Minutes during Skin Stimulation' [Neuroscience 414C (2019) 245-254]. Neuroscience, 416, 294.Elsevier. doi: 10.1016/j.neuroscience.2019.08.012.
Taylor, I.M., Patel, N.A., Freedman, N.C., Castagnola, E., & Cui, X.T. (2019). Direct in Vivo Electrochemical Detection of Resting Dopamine Using Poly(3,4-ethylenedioxythiophene)/Carbon Nanotube Functionalized Microelectrodes. Anal Chem, 91(20), 12917-12927.American Chemical Society (ACS). doi: 10.1021/acs.analchem.9b02904.
Carli, S., Lambertini, L., Zucchini, E., Ciarpella, F., Scarpellini, A., Prato, M., Castagnola, E., Fadiga, L., & Ricci, D. (2018). Single walled carbon nanohorns composite for neural sensing and stimulation. SENSORS AND ACTUATORS B-CHEMICAL, 271, 280-288.Elsevier. doi: 10.1016/j.snb.2018.05.083.
Castagnola, E., Vahidi, N.W., Nimbalkar, S., Rudraraju, S., Thielk, M., Zucchini, E., Cea, C., Carli, S., Gentner, T.Q., Ricci, D., Fadiga, L., & Kassegne, S. (2018). In Vivo Dopamine Detection and Single Unit Recordings Using Intracortical Glassy Carbon Microelectrode Arrays. MRS Adv, 3(29), 1629-1634.Springer Nature. doi: 10.1557/adv.2018.98.
Goshi, N., Castagnola, E., Vomero, M., Gueli, C., Cea, C., Zucchini, E., Bjanes, D., Maggiolini, E., Moritz, C., Kassegne, S., Ricci, D., & Fadiga, L. (2018). Glassy carbon MEMS for novel origami-styled 3D integrated intracortical and epicortical neural probes. JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 28(6), 065009.IOP Publishing. doi: 10.1088/1361-6439/aab061.
Kosugi, A., Takemi, M., Tia, B., Castagnola, E., Ansaldo, A., Sato, K., Awiszus, F., Seki, K., Ricci, D., Fadiga, L., Iriki, A., & Ushiba, J. (2018). Accurate motor mapping in awake common marmosets using micro-electrocorticographical stimulation and stochastic threshold estimation. J Neural Eng, 15(3), 036019.IOP Publishing. doi: 10.1088/1741-2552/aab307.
Nimbalkar, S., Castagnola, E., Balasubramani, A., Scarpellini, A., Samejima, S., Khorasani, A., Boissenin, A., Thongpang, S., Moritz, C., & Kassegne, S. (2018). Ultra-Capacitive Carbon Neural Probe Allows Simultaneous Long-Term Electrical Stimulations and High-Resolution Neurotransmitter Detection. Sci Rep, 8(1), 6958.Springer Nature. doi: 10.1038/s41598-018-25198-x.
Vomero, M., Castagnola, E., Ordonez, J.S., Carli, S., Zucchini, E., Maggiolini, E., Gueli, C., Goshi, N., Ciarpella, F., Cea, C., Fadiga, L., Ricci, D., Kassegne, S., & Stieglitz, T. (2018). Incorporation of Silicon Carbide and Diamond-Like Carbon as Adhesion Promoters Improves In Vitro and In Vivo Stability of Thin-Film Glassy Carbon Electrocorticography Arrays. ADVANCED BIOSYSTEMS, 2(1).Wiley. doi: 10.1002/adbi.201700081.
Castagnola, E., Carli, S., Vomero, M., Scarpellini, A., Prato, M., Goshi, N., Fadiga, L., Kassegne, S., & Ricci, D. (2017). Multilayer poly(3,4-ethylenedioxythiophene)-dexamethasone and poly(3,4-ethylenedioxythiophene)-polystyrene sulfonate-carbon nanotubes coatings on glassy carbon microelectrode arrays for controlled drug release. Biointerphases, 12(3), 031002.American Vacuum Society. doi: 10.1116/1.4993140.
Rembado, I., Castagnola, E., Turella, L., Ius, T., Budai, R., Ansaldo, A., Angotzi, G.N., Debertoldi, F., Ricci, D., Skrap, M., & Fadiga, L. (2017). Independent Component Decomposition of Human Somatosensory Evoked Potentials Recorded by Micro-Electrocorticography. Int J Neural Syst, 27(4), 1650052.World Scientific Publishing. doi: 10.1142/S0129065716500520.
Takemi, M., Castagnola, E., Ansaldo, A., Ricci, D., Fadiga, L., Taoka, M., Iriki, A., & Ushiba, J. (2017). Rapid Identification of Cortical Motor Areas in Rodents by High-Frequency Automatic Cortical Stimulation and Novel Motor Threshold Algorithm. Front Neurosci, 11(OCT), 580.Frontiers. doi: 10.3389/fnins.2017.00580.
Tia, B., Takemi, M., Kosugi, A., Castagnola, E., Ansaldo, A., Nakamura, T., Ricci, D., Ushiba, J., Fadiga, L., & Iriki, A. (2017). Cortical control of object-specific grasp relies on adjustments of both activity and effective connectivity: a common marmoset study. J Physiol, 595(23), 7203-7221.Wiley. doi: 10.1113/JP274629.
Vomero, M., Castagnola, E., Ciarpella, F., Maggiolini, E., Goshi, N., Zucchini, E., Carli, S., Fadiga, L., Kassegne, S., & Ricci, D. (2017). Highly Stable Glassy Carbon Interfaces for Long-Term Neural Stimulation and Low-Noise Recording of Brain Activity. Sci Rep, 7(1), 40332.Springer Nature. doi: 10.1038/srep40332.
Castagnola, E., Maggiolini, E., Ceseracciu, L., Ciarpella, F., Zucchini, E., De Faveri, S., Fadiga, L., & Ricci, D. (2016). pHEMA Encapsulated PEDOT-PSS-CNT Microsphere Microelectrodes for Recording Single Unit Activity in the Brain. Front Neurosci, 10(APR), 151.Frontiers. doi: 10.3389/fnins.2016.00151.
Angotzi, G.N., Baranauskas, G., Vato, A., Bonfanti, A., Zambra, G., Maggiolini, E., Semprini, M., Ricci, D., Ansaldo, A., Castagnola, E., Ius, T., Skrap, M., & Fadiga, L. (2015). A compact and autoclavable system for acute extracellular neural recording and brain pressure monitoring for humans. IEEE Trans Biomed Circuits Syst, 9(1), 50-59.Institute of Electrical and Electronics Engineers (IEEE). doi: 10.1109/TBCAS.2014.2312794.
Castagnola, E., Maiolo, L., Maggiolini, E., Minotti, A., Marrani, M., Maita, F., Pecora, A., Angotzi, G.N., Ansaldo, A., Boffini, M., Fadiga, L., Fortunato, G., & Ricci, D. (2015). PEDOT-CNT-Coated Low-Impedance, Ultra-Flexible, and Brain-Conformable Micro-ECoG Arrays. IEEE Trans Neural Syst Rehabil Eng, 23(3), 342-350.Institute of Electrical and Electronics Engineers (IEEE). doi: 10.1109/TNSRE.2014.2342880.
Castagnola, E., Ansaldo, A., Maggiolini, E., Ius, T., Skrap, M., Ricci, D., & Fadiga, L. (2014). Smaller, softer, lower-impedance electrodes for human neuroprosthesis: a pragmatic approach. Front Neuroeng, 7(APR), 8.Frontiers. doi: 10.3389/fneng.2014.00008.
Castagnola, E., Ansaldo, A., Maggiolini, E., Angotzi, G.N., Skrap, M., Ricci, D., & Fadiga, L. (2013). Biologically compatible neural interface to safely couple nanocoated electrodes to the surface of the brain. ACS Nano, 7(5), 3887-3895.American Chemical Society (ACS). doi: 10.1021/nn305164c.
Ansaldo, A., Castagnola, E., Maggiolini, E., Fadiga, L., & Ricci, D. (2011). Superior electrochemical performance of carbon nanotubes directly grown on sharp microelectrodes. ACS Nano, 5(3), 2206-2214.American Chemical Society (ACS). doi: 10.1021/nn103445d.
Baranauskas, G., Maggiolini, E., Castagnola, E., Ansaldo, A., Mazzoni, A., Angotzi, G.N., Vato, A., Ricci, D., Panzeri, S., & Fadiga, L. (2011). Carbon nanotube composite coating of neural microelectrodes preferentially improves the multiunit signal-to-noise ratio. J Neural Eng, 8(6), 066013.IOP Publishing. doi: 10.1088/1741-2560/8/6/066013.
Castagnola, E., Ansaldo, A., Fadiga, L., & Ricci, D. (2010). Chemical vapour deposited carbon nanotube coated microelectrodes for intracortical neural recording. PHYSICA STATUS SOLIDI B-BASIC SOLID STATE PHYSICS, 247(11-12), 2703-2707.Wiley. doi: 10.1002/pssb.201000217.
Castagnola, E., Biso, M., & Ricci, D. (2009). Improvement of polypyrrole and carbon nanotube co-deposition techniques for high charge-transfer electrodes. PHYSICA STATUS SOLIDI B-BASIC SOLID STATE PHYSICS, 246(11-12), 2469-2472.Wiley. doi: 10.1002/pssb.200982283.
Vomero, M., Castagnola, E., Ordonez, J.S., Carli, S., Zucchini, E., Maggiolini, E., Gueli, C., Goshi, N., Fadiga, L., Ricci, D., Kassegne, S., & Stieglitz, T. (2017). Improved Long-Term Stability of Thin-Film Glassy Carbon Electrodes Through the use of Silicon Carbide and Amorphous Carbon. In 2017 8th International IEEE/EMBS Conference on Neural Engineering (NER), (pp. 288-291).Institute of Electrical and Electronics Engineers (IEEE). doi: 10.1109/ner.2017.8008347.
Castagnola, E., De Faveri, S., Ansaldo, A., Maggiolini, E., Benfenati, F., Ricci, D., & Fadiga, L. (2015). Nanostructured Microsphere Coated with Living Cells and Tethered with Low-Stiffness Wire: A Possible Solution to Brain Tissue Reactions**Research supported by Istituto Italiano di Tecnologia. In 2015 7th International IEEE/EMBS Conference on Neural Engineering (NER), 2015-July, (pp. 390-393).Institute of Electrical and Electronics Engineers (IEEE). doi: 10.1109/ner.2015.7146641.
Castagnola, E., Maiolo, L., Maggiolini, E., Minotti, A., Marrani, M., Maita, F., Pecora, A., Angotzi, G.N., Ansaldo, A., Fadiga, L., Fortunato, G., & Ricci, D. (2013). Ultra-flexible and brain-conformable micro-electrocorticography device with low impedance PEDOT-carbon nanotube coated microelectrodes. In 2013 6th International IEEE/EMBS Conference on Neural Engineering (NER), (pp. 927-930).Institute of Electrical and Electronics Engineers (IEEE). doi: 10.1109/ner.2013.6696087.
Castagnola, E., Biso, M., & Ricci, D. (2009). Controlled electrochemical polypyrrole and carbon nanotube co-deposition onto platinum electrodes. In 2009 9th IEEE Conference on Nanotechnology, IEEE NANO 2009, (pp. 842-845).