headshot of Yadong Wang

Yadong Wang

Professor
Bio materials Foundry Bioengineering Department Mechanical Engineering & Materials Science

about

(2014) Elected Fellow, AIMBE.

(2013) Dutch Heart Foundation Lecture, International Symposium on Vascular Tissue Engineering, Leiden, The Netherlands.

(2012) American Heart Association Established Investigator Award.

(2012) Randall Family Big Idea Competition, 1st Place Winner (Mentor).

(2012) CMU Summit New Venture Competition, 1st Place Winner (Mentor).

(2008) Best Undergraduate Advisor Award, BMES Georgia Tech Chapter.

(2007) Member, Advisory Board, Lifeboat Foundation.

(2007) American Heart Association Scientist Development Award.

(2007) Best Professor Award, BMES Georgia Tech Chapter.

(2007) SAIC Outstanding Research Paper Award.

(2007) Hunter Chair Lecture, Clemson University.

(2005) Finalist, the INDEX: Award, Copenhagen, Denmark.

(1998 - 1999) Franklin Veatch Memorial Scholarship, Stanford University.

PhD, Chemistry, Stanford University, 1999

M.S., Chemistry, Kansas State University, 1995

Ângelo, D.F., Monje, F.G., González-García, R., Little, C.B., Mónico, L., Pinho, M., Santos, F.A., Carrapiço, B., Gonçalves, S.C., Morouço, P., Alves, N., Moura, C., Wang, Y., Jeffries, E., Gao, J., Sousa, R., Neto, L.L., Caldeira, D., & Salvado, F. (2017). Bioengineered Temporomandibular Joint Disk Implants: Study Protocol for a Two-Phase Exploratory Randomized Preclinical Pilot Trial in 18 Black Merino Sheep (TEMPOJIMS). JMIR Research Protocols, 6(3), e37.JMIR Publications. doi: 10.2196/resprot.6779.

Awada, H.K., Long, D.W., Wang, Z., Hwang, M.P., Kim, K., & Wang, Y. (2017). A single injection of protein-loaded coacervate-gel significantly improves cardiac function post infarction. BIOMATERIALS, 125, 65-80.Elsevier. doi: 10.1016/j.biomaterials.2017.02.020.

Long, D.W., Johnson, N.R., Jeffries, E.M., Hara, H., & Wang, Y. (2017). Controlled delivery of platelet-derived proteins enhances porcine wound healing. JOURNAL OF CONTROLLED RELEASE, 253, 73-81.Elsevier. doi: 10.1016/j.jconrel.2017.03.021.

Awada, H.K., Hwang, M.P., & Wang, Y. (2016). Towards comprehensive cardiac repair and regeneration after myocardial infarction: Aspects to consider and proteins to deliver. BIOMATERIALS, 82, 94-112.Elsevier. doi: 10.1016/j.biomaterials.2015.12.025.

Ding, X., Gao, J., Wang, Z., Awada, H., & Wang, Y. (2016). A shear-thinning hydrogel that extends in vivo bioactivity of FGF2. BIOMATERIALS, 111, 80-89.Elsevier. doi: 10.1016/j.biomaterials.2016.09.026.

Awada, H.K., Johnson, N.R., & Wang, Y. (2015). Sequential delivery of angiogenic growth factors improves revascularization and heart function after myocardial infarction. JOURNAL OF CONTROLLED RELEASE, 207, 7-17.Elsevier. doi: 10.1016/j.jconrel.2015.03.034.

Chen, W.C.W., Lee, B.G., Park, D.W., Kim, K., Chu, H., Kim, K., Huard, J., & Wang, Y. (2015). Controlled dual delivery of fibroblast growth factor-2 and Interleukin-10 by heparin-based coacervate synergistically enhances ischemic heart repair. BIOMATERIALS, 72, 138-151.Elsevier. doi: 10.1016/j.biomaterials.2015.08.050.

Jeffries, E.M., Allen, R.A., Gao, J., Pesce, M., & Wang, Y. (2015). Highly elastic and suturable electrospun poly(glycerol sebacate) fibrous scaffolds. ACTA BIOMATERIALIA, 18, 30-39.Elsevier. doi: 10.1016/j.actbio.2015.02.005.

Johnson, N.R., & Wang, Y. (2015). Drug delivery systems for wound healing. Current Pharmaceutical Biotechnology, 16(7), 621-629.Bentham Science Publishers. doi: 10.2174/1389201016666150206113720.

Rauck, B.M., Novosat, T.L., Oudega, M., & Wang, Y. (2015). Biocompatibility of a coacervate-based controlled release system for protein delivery to the injured spinal cord. ACTA BIOMATERIALIA, 11(C), 204-211.Elsevier. doi: 10.1016/j.actbio.2014.09.037.

Xiao, J., Wang, Y., Bellusci, S., & Li, X. (2015). Pharmacological Application of Growth Factors: Basic and Clinical. BioMed Research International, 2015(1), 141794.Hindawi. doi: 10.1155/2015/141794.

Allen, R.A., Wu, W., Yao, M., Dutta, D., Duan, X., Bachman, T.N., Champion, H.C., Stolz, D.B., Robertson, A.M., Kim, K., Isenberg, J.S., & Wang, Y. (2014). Nerve regeneration and elastin formation within poly(glycerol sebacate)-based synthetic arterial grafts one-year post-implantation in a rat model. BIOMATERIALS, 35(1), 165-173.Elsevier. doi: 10.1016/j.biomaterials.2013.09.081.

Awada, H.K., Johnson, N.R., & Wang, Y. (2014). Dual Delivery of Vascular Endothelial Growth Factor and Hepatocyte Growth Factor Coacervate Displays Strong Angiogenic Effects. MACROMOLECULAR BIOSCIENCE, 14(5), 679-686.Wiley. doi: 10.1002/mabi.201300486.

Bae, H., Chu, H., Edalat, F., Cha, J.M., Sant, S., Kashyap, A., Ahari, A.F., Kwon, C.H., Nichol, J.W., Manoucheri, S., Zamanian, B., Wang, Y., & Khademhosseini, A. (2014). Development of functional biomaterials with micro- and nanoscale technologies for tissue engineering and drug delivery applications. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 8(1), 1-14.Hindawi. doi: 10.1002/term.1494.

Bi, X., You, Z., Gao, J., Fan, X., & Wang, Y. (2014). A functional polyester carrying free hydroxyl groups promotes the mineralization of osteoblast and human mesenchymal stem cell extracellular matrix. ACTA BIOMATERIALIA, 10(6), 2814-2823.Elsevier. doi: 10.1016/j.actbio.2014.02.018.

Deng, Y., Bi, X., Zhou, H., You, Z., Wang, Y., Gu, P., & Fan, X. (2014). REPAIR OF CRITICAL-SIZED BONE DEFECTS WITH ANTI-MIR-31-EXPRESSING BONE MARROW STROMAL STEM CELLS AND POLY(GLYCEROL SEBACATE) SCAFFOLDS. EUROPEAN CELLS & MATERIALS, 27, 13-25.European Cells and Materials. doi: 10.22203/eCM.v027a02.

Johnson, N.R., Ambe, T., & Wang, Y. (2014). Lysine-based polycation:heparin coacervate for controlled protein delivery. ACTA BIOMATERIALIA, 10(1), 40-46.Elsevier. doi: 10.1016/j.actbio.2013.09.012.

Rauck, B.M., Friberg, T.R., Mendez, C.A.M., Park, D., Shah, V., Bilonick, R.A., & Wang, Y. (2014). Biocompatible Reverse Thermal Gel Sustains the Release of Intravitreal Bevacizumab In Vivo. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 55(1), 469-476.Association for Research in Vision and Ophthalmology (ARVO). doi: 10.1167/iovs.13-13120.

Ritfeld, G.J., Rauck, B.M., Novosat, T.L., Park, D., Patel, P., Roos, R.A.C., Wang, Y., & Oudega, M. (2014). The effect of a polyurethane-based reverse thermal gel on bone marrow stromal cell transplant survival and spinal cord repair. BIOMATERIALS, 35(6), 1924-1931.Elsevier. doi: 10.1016/j.biomaterials.2013.11.062.

Zaky, S.H., Hangadora, C.K., Tudares, M.A., Gao, J., Jensen, A., Wang, Y., Sfeir, C., & Almarza, A.J. (2014). Poly (glycerol sebacate) elastomer supports osteogenic phenotype for bone engineering applications. BIOMEDICAL MATERIALS, 9(2), 025003.IOP Publishing. doi: 10.1088/1748-6041/9/2/025003.

Zaky, S.H., Lee, K.W., Gao, J., Jensen, A., Close, J., Wang, Y., Almarza, A.J., & Sfeir, C. (2014). Poly(Glycerol Sebacate) Elastomer: A Novel Material for Mechanically Loaded Bone Regeneration. TISSUE ENGINEERING PART A, 20(1-2), 45-53.Mary Ann Liebert. doi: 10.1089/ten.tea.2013.0172.

Chu, H., Chen, C.W., Huard, J., & Wang, Y. (2013). The effect of a heparin-based coacervate of fibroblast growth factor-2 on scarring in the infarcted myocardium. BIOMATERIALS, 34(6), 1747-1756.Elsevier. doi: 10.1016/j.biomaterials.2012.11.019.

Dutta, D., Lee, K.W., Allen, R.A., Wang, Y., Brigham, J.C., & Kim, K. (2013). NON-INVASIVE ASSESSMENT OF ELASTIC MODULUS OF ARTERIAL CONSTRUCTS DURING CELL CULTURE USING ULTRASOUND ELASTICITY IMAGING. ULTRASOUND IN MEDICINE AND BIOLOGY, 39(11), 2103-2115.Elsevier. doi: 10.1016/j.ultrasmedbio.2013.04.023.

Hagandora, C.K., Gao, J., Wang, Y., & Almarza, A.J. (2013). Poly (Glycerol Sebacate): A Novel Scaffold Material for Temporomandibular Joint Disc Engineering. TISSUE ENGINEERING PART A, 19(5-6), 729-737.Mary Ann Liebert. doi: 10.1089/ten.tea.2012.0304.

Jeffries, E.M., & Wang, Y. (2013). Incorporation of parallel electrospun fibers for improved topographical guidance in 3D nerve guides. BIOFABRICATION, 5(3), 035015.IOP Publishing. doi: 10.1088/1758-5082/5/3/035015.

Johnson, N.R., & Wang, Y. (2013). Controlled delivery of heparin-binding EGF-like growth factor yields fast and comprehensive wound healing. JOURNAL OF CONTROLLED RELEASE, 166(2), 124-129.Elsevier. doi: 10.1016/j.jconrel.2012.11.004.

Johnson, N.R., & Wang, Y. (2013). Controlled Delivery of Sonic Hedgehog Morphogen and Its Potential for Cardiac Repair. In Qin, G. (Ed.). PLOS ONE, 8(5), e63075.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0063075.

Lee, K.W., Johnson, N.R., Gao, J., & Wang, Y. (2013). Human progenitor cell recruitment via SDF-1α coacervate-laden PGS vascular grafts. BIOMATERIALS, 34(38), 9877-9885.Elsevier. doi: 10.1016/j.biomaterials.2013.08.082.

Li, H., Johnson, N.R., Usas, A., Lu, A., Poddar, M., Wang, Y., & Huard, J. (2013). Sustained Release of Bone Morphogenetic Protein 2 via Coacervate Improves the Osteogenic Potential of Muscle-Derived Stem Cells. STEM CELLS TRANSLATIONAL MEDICINE, 2(9), 667-677.Oxford University Press (OUP). doi: 10.5966/sctm.2013-0027.

Li, H., Johnson, N.R., Usas, A., Lu, A., Wang, Y., & Huard, J. (2013). Sustained Release of BMP2 via Coacervate Improves the Osteogenic Potential of Muscle-Derived Stem Cells. Stem Cells Translational Medicine, 2(9), 667-677.

Park, D., Larson, A.M., Klibanov, A.M., & Wang, Y. (2013). Antiviral and Antibacterial Polyurethanes of Various Modalities. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 169(4), 1134-1146.Springer Nature. doi: 10.1007/s12010-012-9999-7.

Park, D., Shah, V., Rauck, B.M., Friberg, T.R., & Wang, Y. (2013). An Anti-angiogenic Reverse Thermal Gel as a Drug-Delivery System for Age-Related Wet Macular Degeneration. MACROMOLECULAR BIOSCIENCE, 13(4), 464-469.Wiley. doi: 10.1002/mabi.201200384.

Saparov, A., Chen, C.W., Beckman, S.A., Wang, Y., & Huard, J. (2013). The Role of Antioxidation and Immunomodulation in Postnatal Multipotent Stem Cell-Mediated Cardiac Repair. International Journal of Molecular Sciences, 14(8), 16258-16279.MDPI. doi: 10.3390/ijms140816258.

Saparoy, A., Chen, C.W., Beckman, S., Wang, Y., & Huard, J. (2013). The Role of Antioxidation and Immunomodulation in Stem Cell-Mediated Cardiac Repair. Int. J. Mol. Sci., 14(8), 16258-16279.

Yu, J., Takanari, K., Hong, Y., Lee, K.W., Amoroso, N.J., Wang, Y., Wagner, W.R., & Kim, K. (2013). Non-invasive characterization of polyurethane-based tissue constructs in a rat abdominal repair model using high frequency ultrasound elasticity imaging. BIOMATERIALS, 34(11), 2701-2709.Elsevier. doi: 10.1016/j.biomaterials.2013.01.036.

Chu, H., & Wang, Y. (2012). Therapeutic angiogenesis: controlled delivery of angiogenic factors. Therapeutic Delivery, 3(6), 693-714.Taylor & Francis. doi: 10.4155/tde.12.50.

Chu, H., Gao, J., & Wang, Y. (2012). Design, synthesis, and biocompatibility of an arginine-based polyester. BIOTECHNOLOGY PROGRESS, 28(1), 257-264.Wiley. doi: 10.1002/btpr.728.

Jeffries, E.M., & Wang, Y. (2012). Biomimetic micropatterned multi-channel nerve guides by templated electrospinning. BIOTECHNOLOGY AND BIOENGINEERING, 109(6), 1571-1582.Wiley. doi: 10.1002/bit.24412.

Wu, W., Allen, R.A., & Wang, Y. (2012). Fast-degrading elastomer enables rapid remodeling of a cell-free synthetic graft into a neoartery. NATURE MEDICINE, 18(7), 1148-+.Springer Nature. doi: 10.1038/nm.2821.

You, Z., & Wang, Y. (2012). A Versatile Synthetic Platform for a Wide Range of Functionalized Biomaterials. ADVANCED FUNCTIONAL MATERIALS, 22(13), 2812-2820.Wiley. doi: 10.1002/adfm.201102024.

You, Z., Bi, X., & Wang, Y. (2012). Fine Control of Polyester Properties via Epoxide ROP Using Monomers Carrying Diverse Functional Groups. MACROMOLECULAR BIOSCIENCE, 12(6), 822-829.Wiley. doi: 10.1002/mabi.201200035.

You, Z., Bi, X., Fan, X., & Wang, Y. (2012). A functional polymer designed for bone tissue engineering. ACTA BIOMATERIALIA, 8(2), 502-510.Elsevier. doi: 10.1016/j.actbio.2011.11.004.

You, Z., Bi, X., Jeffries, E.M., & Wang, Y. (2012). A biocompatible, metal-free catalyst and its application in microwave-assisted synthesis of functional polyesters. POLYMER CHEMISTRY, 3(2), 384-389.Royal Society of Chemistry (RSC). doi: 10.1039/c1py00400j.

Allen, R., & Wang, Y. (2011). Formidable Challenges in the Search for Biomarkers of Psychiatric Disorders. Journal of Tissue Science & Engineering, 02(03), 1000105e.OMICS International. doi: 10.4172/2157-7552.1000105e.

Chu, H., Gao, J., Chen, C.W., Huard, J., & Wang, Y. (2011). Injectable fibroblast growth factor-2 coacervate for persistent angiogenesis. In Langer, R. (Ed.). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(33), 13444-13449.Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.1110121108.

Chu, H., Johnson, N.R., Mason, N.S., & Wang, Y. (2011). A [polycation:heparin] complex releases growth factors with enhanced bioactivity. JOURNAL OF CONTROLLED RELEASE, 150(2), 157-163.Elsevier. doi: 10.1016/j.jconrel.2010.11.025.

Crapo, P.M., & Wang, Y. (2011). Hydrostatic pressure independently increases elastin and collagen co-expression in small-diameter engineered arterial constructs. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 96A(4), 673-681.Wiley. doi: 10.1002/jbm.a.33019.

Gumera, C., Rauck, B., & Wang, Y. (2011). Materials for central nervous system regeneration: bioactive cues. JOURNAL OF MATERIALS CHEMISTRY, 21(20), 7033-7051.Royal Society of Chemistry (RSC). doi: 10.1039/c0jm04335d.

Lee, K.W., & Wang, Y. (2011). Elastomeric PGS Scaffolds in Arterial Tissue Engineering. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (50), 2691.MyJove. doi: 10.3791/2691.

Park, D., Wu, W., & Wang, Y. (2011). A functionalizable reverse thermal gel based on a polyurethane/PEG block copolymer. BIOMATERIALS, 32(3), 777-786.Elsevier. doi: 10.1016/j.biomaterials.2010.09.044.

Wilson, M.E., Kota, N., Kim, Y., Wang, Y., Stolz, D.B., LeDuc, P.R., & Ozdoganlar, O.B. (2011). Fabrication of circular microfluidic channels by combining mechanical micromilling and soft lithography. LAB ON A CHIP, 11(8), 1550-1555.Royal Society of Chemistry (RSC). doi: 10.1039/c0lc00561d.

Wu, W., Allen, R., Gao, J., & Wang, Y. (2011). Artificial Niche Combining Elastomeric Substrate and Platelets Guides Vascular Differentiation of Bone Marrow Mononuclear Cells. TISSUE ENGINEERING PART A, 17(15-16), 1979-1992.Mary Ann Liebert. doi: 10.1089/ten.tea.2010.0550.

Zern, B.J., Chu, H., Osunkoya, A.O., Gao, J., & Wang, Y. (2011). A Biocompatible Arginine-Based Polycation. ADVANCED FUNCTIONAL MATERIALS, 21(3), 434-440.Wiley. doi: 10.1002/adfm.201000969.

Crapo, P.M., & Wang, Y. (2010). Physiologic compliance in engineered small-diameter arterial constructs based on an elastomeric substrate. BIOMATERIALS, 31(7), 1626-1635.Elsevier. doi: 10.1016/j.biomaterials.2009.11.035.

Crapo, P.M., & Wang, Y. (2010). Small intestinal submucosa gel as a potential scaffolding material for cardiac tissue engineering. ACTA BIOMATERIALIA, 6(6), 2091-2096.Elsevier. doi: 10.1016/j.actbio.2009.10.048.

Marsano, A., Maidhof, R., Wan, L.Q., Wang, Y., Gao, J., Tandon, N., & Vunjak-Novakovic, G. (2010). Scaffold Stiffness Affects the Contractile Function of Three-Dimensional Engineered Cardiac Constructs. BIOTECHNOLOGY PROGRESS, 26(5), 1382-1390.Wiley. doi: 10.1002/btpr.435.

You, Z., Cao, H., Gao, J., Shin, P.H., Day, B.W., & Wang, Y. (2010). A functionalizable polyester with free hydroxyl groups and tunable physiochemical and biological properties. BIOMATERIALS, 31(12), 3129-3138.Elsevier. doi: 10.1016/j.biomaterials.2010.01.023.

Zern, B.J., Chu, H., & Wang, Y. (2010). Control Growth Factor Release Using a Self-Assembled [polycation:heparin] Complex. In Zhang, S. (Ed.). PLOS ONE, 5(6), e11017.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0011017.

Lee, E.J., Vunjak-Novakovic, G., Wang, Y., & Niklason, L.E. (2009). A Biocompatible Endothelial Cell Delivery System for In Vitro Tissue Engineering. CELL TRANSPLANTATION, 18(7), 731-743.SAGE Publications. doi: 10.3727/096368909X470919.

Sales, V.L., Kim, G.S., Gao, J., Rusk, E., Matthews, E., Wang, Y., Martin, D., Estrada, C., Walter, E.M.B., & Mayer, J.E.J. (2009). Customizing Future Tissue Engineered Heart Valves Through Phenotypic Modulation of Progenitor Cells. CIRCULATION, 120(18), S597.

Secasanu, V.P., Giardina, C.K., & Wang, Y. (2009). A Novel Electrospinning Target to Improve the Yield of Uniaxially Aligned Fibers. BIOTECHNOLOGY PROGRESS, 25(4), 1169-1175.Wiley. doi: 10.1002/btpr.163.

Wang, Y., Goh, S.H., Bi, X., & Yang, K.L. (2009). Replication of DNA submicron patterns by combining nanoimprint lithography and contact printing. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 333(1), 188-194.Elsevier. doi: 10.1016/j.jcis.2009.02.010.

Crapo, P., Gao, J., & Wang, Y. (2008). Seamless Tubular Poly(glycerol sebacate) Scaffolds: High-yield Fabrication and Potential Applications. J. Biomed. Mat. Res. 86: 354-363, 2008. J. Biomed. Mat. Res., 86, 354-363.

Crapo, P.M., Gao, J., & Wang, Y. (2008). Seamless tubular poly(glycerol sebacate) scaffolds: High-yield fabrication and potential applications. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 86A(2), 354-363.Wiley. doi: 10.1002/jbm.a.31598.

Gao, J., Crapo, P., Nerern, R., & Wang, Y. (2008). Co-expression of elastin and collagen leads to highly compliant engineered blood vessels. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 85A(4), 1120-1128.Wiley. doi: 10.1002/jbm.a.32028.

Radisic, M., Marsano, A., Maidhof, R., Wang, Y., & Vunjak-Novakovic, G. (2008). Cardiac tissue engineering using perfusion bioreactor systems. NATURE PROTOCOLS, 3(4), 719-738.Springer Nature. doi: 10.1038/nprot.2008.40.

Radisic, M., Park, H., Martens, T.P., Salazar-Lazaro, J.E., Geng, W., Wang, Y., Langer, R., Freed, L.E., & Vunjak-Novakovic, G. (2008). Pre-treatment of synthetic elastomeric scaffolds by cardiac fibroblasts improves engineered heart tissue. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 86A(3), 713-724.Wiley. doi: 10.1002/jbm.a.31578.

Gao, J., Ensley, A.E., Nerem, R.M., & Wang, Y. (2007). Poly(glycerol sebacate) supports the proliferation and phenotypic protein expression of primary baboon vascular cells. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 83A(4), 1070-1075.Wiley. doi: 10.1002/jbm.a.31434.

Gumera, C.B., & Wang, Y. (2007). Modulating neuronal responses by controlled integration of acetylcholine-like functionalities in biomimetic polymers. ADVANCED MATERIALS, 19(24), 4404-+.Wiley. doi: 10.1002/adma.200701747.

Kim, Y.M., Gao, J., Zern, B., & Wang, Y.D. (2007). Biofunctional Materials for Nerve Regeneration. Materials Science Forum, 539-543(PART 1), 547-550.Trans Tech Publications Ltd. doi: 10.4028/0-87849-428-6.547.

Sales, V.L., Engelmayr, G.C.J., Johnson, J.A.J., Gao, J., Wang, Y., Sacks, M.S., & Mayer, J.E. (2007). Protein precoating of elastomeric tissue-engineering scaffolds increased cellularity, enhanced extracellular matrix protein production, and differentially regulated the phenotypes of circulating endothelial progenitor cells. CIRCULATION, 116(11), I55-I63.Wolters Kluwer. doi: 10.1161/CIRCULATIONAHA.106.6806637.

Bettinger, C.J., Weinberg, E.J., Kulig, K.M., Vacanti, J.P., Wang, Y.D., Borenstein, J.T., & Langer, R. (2006). Three-dimensional microfluidic tissue-engineering scaffolds using a flexible biodegradable polymer. ADVANCED MATERIALS, 18(2), 165-+.Wiley. doi: 10.1002/adma.200500438.

Gao, J., Crapo, P.M., & Wang, Y. (2006). Macroporous elastomeric scaffolds with extensive micropores for soft tissue engineering. TISSUE ENGINEERING, 12(4), 917-925.Mary Ann Liebert. doi: 10.1089/ten.2006.12.917.

Gao, J., Kim, Y.M., Coe, H., Zern, B., Sheppard, B., & Wang, Y. (2006). A neuroinductive biomaterial based on dopamine. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103(45), 16681-16686.Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.0606237103.

Sales, V.L., Engelmayr, G.C.J., Gottlieb, D., Johnson, J.A.J., Gao, J., Wang, Y., Sacks, M.S., & Mayer, J.E.J. (2006). Protein precoating of elastomeric tissue-engineering scaffolds: Extracellular matrix formation and phenotypic changes of circulating endothelial progenitor cells. CIRCULATION RESEARCH, 99(5), E35.

Wang, Y., Gao, J., Kim, Y., Coe, H., Zern, B., & Sheppard, B. (2006). A Neuro-inductive Biodegradable Material Based on Dopamine. Proc. Natl. Acad. Sci. U.S.A., 103, 16681-16686.

Fidkowski, C., Kaazempur-Mofrad, M.R., Borenstein, J., Vacanti, J.P., Langer, R., & Wang, Y.D. (2005). Endothelialized microvasculature based on a biodegradable elastomer. TISSUE ENGINEERING, 11(1-2), 302-309.Mary Ann Liebert. doi: 10.1089/ten.2005.11.302.

Haaga, J.R., Exner, A.A., Wang, Y.D., Stowe, N.T., & Tarcha, P.J. (2005). Combined tumor therapy by using radiofrequency ablation and 5-FU-laden polymer implants: Evaluation in rats and rabbits. RADIOLOGY, 237(3), 911-918.Radiological Society of North America (RSNA). doi: 10.1148/radiol.2373041950.

Sundback, C.A., Shyu, J.Y., Wang, Y.D., Faquin, W.C., Langer, R.S., Vacanti, J.P., & Hadlock, T.A. (2005). Biocompatibility analysis of poly(glycerol sebacate) as a nerve guide material. BIOMATERIALS, 26(27), 5454-5464.Elsevier. doi: 10.1016/j.biomaterials.2005.02.004.

Ijima, H., Wang, Y.D., & Langer, R. (2004). Spheroid formation and expression of liver specific functions of primary rat hepatocytes co-cultured with bone marrow cells. BIOCHEMICAL ENGINEERING JOURNAL, 20(2-3), 223-228.Elsevier. doi: 10.1016/j.bej.2003.09.014.

Wang, Y.D., Kim, Y.M., & Langer, R. (2003). In vivo degradation characteristics of poly(glycerol sebacate). JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 66A(1), 192-197.Wiley. doi: 10.1002/jbm.a.10534.

Wang, Y.D., Ameer, G.A., Sheppard, B.J., & Langer, R. (2002). A tough biodegradable elastomer. NATURE BIOTECHNOLOGY, 20(6), 602-606.Springer Nature. doi: 10.1038/nbt0602-602.

Wang, Y.D., DuBois, J.L., Hedman, B., Hodgson, K.O., & Stack, T.D.P. (1998). Catalytic galactose oxidase models: Biomimetic Cu(II)-phenoxyl-radical reactivity. SCIENCE, 279(5350), 537-540.American Association for the Advancement of Science (AAAS). doi: 10.1126/science.279.5350.537.

Wang, Y.D., & Stack, T.D.P. (1996). Galactose oxidase model complexes: Catalytic reactivities. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 118(51), 13097-13098.American Chemical Society (ACS). doi: 10.1021/ja9621354.

Research interests

controlled release of proteins
drug delivery
Polymeric biomaterials
wound healing