My lab develops multimodal neuroimaging platforms to explore systems-level neurovascular and metabolic events during neurogenesis, normal development and neurodegeneration. We employ a set of interdisciplinary approaches that combine molecular tools such as optogenetics and reporter protein design with systems-level methods such as in vivo multichannel electrophysiology, Magnetic Resonance Imaging, two-photon and intrinsic optical imaging. We collect multi-modal datasets and use bioimage and signal processing algorithms to identify accessible molecular targets connected to brain dysfunction.