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Douglass Taylor

Professor
Bioengineering Department

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Gough, A., Soto-Gutierrez, A., Vernetti, L., Ebrahimkhani, M.R., Stern, A.M., & Taylor, D.L. (2021). Human biomimetic liver microphysiology systems in drug development and precision medicine. NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 18(4), 252-268.Springer Science and Business Media LLC. doi: 10.1038/s41575-020-00386-1.

Kochanek, P.M., Jackson, T.C., Jha, R.M., Clark, R.S.B., Okonkwo, D.O., Bayir, H., Poloyac, S.M., Wagner, A.K., Empey, P.E., Conley, Y.P., Bell, M.J., Kline, A.E., Bondi, C.O., Simon, D.W., Carlson, S.W., Puccio, A.M., Horvat, C.M., Au, A.K., Elmer, J., Treble-Barna, A., Ikonomovic, M.D., Shutter, L.A., Taylor, D.L., Stern, A.M., Graham, S.H., Kagan, V.E., Jackson, E.K., Wisniewski, S.R., & Dixon, C.E. (2020). Paths to Successful Translation of New Therapies for Severe Traumatic Brain Injury in the Golden Age of Traumatic Brain Injury Research: A Pittsburgh Vision. JOURNAL OF NEUROTRAUMA, 37(22), 2353-2371.Mary Ann Liebert Inc. doi: 10.1089/neu.2018.6203.

Miedel, M.T., Gavlock, D.C., Jia, S., Gough, A., Taylor, D.L., & Stern, A.M. (2019). Modeling the Effect of the Metastatic Microenvironment on Phenotypes Conferred by Estrogen Receptor Mutations Using a Human Liver Microphysiological System. SCIENTIFIC REPORTS, 9(1), 8341.Springer Science and Business Media LLC. doi: 10.1038/s41598-019-44756-5.

Taylor, D.L., Gough, A., Schurdak, M.E., Vernetti, L., Chennubhotla, C.S., Lefever, D., Pei, F., Faeder, J.R., Lezon, T.R., Stern, A.M., & Bahar, I. (2019). Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology. Handb Exp Pharmacol, 260, 327-367.Springer International Publishing. doi: 10.1007/164_2019_239.

Li, X., George, S.M., Vernetti, L., Gough, A.H., & Taylor, D.L. (2018). A glass-based, continuously zonated and vascularized human liver acinus microphysiological system (vLAMPS) designed for experimental modeling of diseases and ADME/TOX. LAB ON A CHIP, 18(17), 2614-2631.Royal Society of Chemistry (RSC). doi: 10.1039/c8lc00418h.

Stern, A.M., Schurdak, M.E., Bahar, I., Berg, J.M., & Taylor, D.L. (2016). A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine. JOURNAL OF BIOMOLECULAR SCREENING, 21(6), 521-534.SAGE Publications. doi: 10.1177/1087057116635818.

Gough, A.H., Chen, N., Shun, T.Y., Lezon, T.R., Boltz, R.C., Reese, C.E., Wagner, J., Vernetti, L.A., Grandis, J.R., Lee, A.V., Stern, A.M., Schurdak, M.E., & Taylor, D.L. (2014). Identifying and Quantifying Heterogeneity in High Content Analysis: Application of Heterogeneity Indices to Drug Discovery. In Paulmurugan, R. (Ed.). PLOS ONE, 9(7), e102678.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0102678.

Bhushan, A., Senutovitch, N., Bale, S.S., McCarty, W.J., Hegde, M., Jindal, R., Golberg, I., Usta, O.B., Yarmush, M.L., Vernetti, L., Gough, A., Bakan, A., Shun, T.Y., DeBiasio, R., & Taylor, D.L. (2013). Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans. STEM CELL RESEARCH & THERAPY, 4(Suppl 1), S16.Springer Science and Business Media LLC. doi: 10.1186/scrt377.