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Brett Kaufman

Associate Professor
Bioengineering Department

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Kolesar, J.E., & Kaufman, B.A. (2020). Using Two-Dimensional Intact Mitochondrial DNA (mtDNA) Agarose Gel Electrophoresis (2D-IMAGE) to Detect Changes in Topology Associated with Mitochondrial Replication, Transcription, and Damage. Methods Mol Biol, 2119, 25-42.Springer US. doi: 10.1007/978-1-0716-0323-9_3.

Rutledge, C., Cater, G., McMahon, B., Guo, L., Nouraie, S.M., Wu, Y., Villanueva, F., & Kaufman, B.A. (2020). Commercial 4-dimensional echocardiography for murine heart volumetric evaluation after myocardial infarction. CARDIOVASCULAR ULTRASOUND, 18(1), 9.Springer Science and Business Media LLC. doi: 10.1186/s12947-020-00191-5.

Ware, S.A., Desai, N., Lopez, M., Leach, D., Zhang, Y., Giordano, L., Nouraie, M., Picard, M., & Kaufman, B.A. (2020). An automated, high-throughput methodology optimized for quantitative cell-free mitochondrial and nuclear DNA isolation from plasma. JOURNAL OF BIOLOGICAL CHEMISTRY, 295(46), 15677-15691.Elsevier BV. doi: 10.1074/jbc.RA120.015237.

Falabella, M., Kolesar, J.E., Wallace, C., de Jesus, D., Sun, L., Taguchi, Y.V., Wang, C., Wang, T., Xiang, I.M., Alder, J.K., Maheshan, R., Horne, W., Turek-Herman, J., Pagano, P.J., St Croix, C.M., Sondheimer, N., Yatsunyk, L.A., Johnson, F.B., & Kaufman, B.A. (2019). G-quadruplex dynamics contribute to regulation of mitochondrial gene expression. SCIENTIFIC REPORTS, 9(1), 5605.Springer Science and Business Media LLC. doi: 10.1038/s41598-019-41464-y.

Trumpff, C., Marsland, A.L., Basualto-Alarcon, C., Martin, J.L., Carroll, J.E., Sturm, G., Vincent, A.E., Mosharov, E.V., Gu, Z., Kaufman, B.A., & Picard, M. (2019). Acute psychological stress increases serum circulating cell-free mitochondrial DNA. PSYCHONEUROENDOCRINOLOGY, 106, 268-276.Elsevier BV. doi: 10.1016/j.psyneuen.2019.03.026.

Falabella, M., Sun, L., Barr, J., Pena, A.Z., Kershaw, E.E., Gingras, S., Goncharova, E.A., & Kaufman, B.A. (2017). Single-Step qPCR and dPCR Detection of Diverse CRISPR-Cas9 Gene Editing Events In Vivo. G3-GENES GENOMES GENETICS, 7(10), 3533-3542.Oxford University Press (OUP). doi: 10.1534/g3.117.300123.

Kaufman, B.A., & Van Houten, B. (2017). POLS: A new role of DNA polymerase beta in mitochondrial base excision repair. DNA REPAIR, 60, A1-A5.Elsevier BV. doi: 10.1016/j.dnarep.2017.11.002.

Research interests

mitochondria
mitochondrial disorders
mtDNA
reactive oxygen species