(2013) Invited Panelist at the National Institutes of Health - 9th Structural Birth Defects Meeting.
(2013) University of Pittsburgh Provost's Innovation in Education Award.
(2012) Appointed Wellington C. Carl Faculty Fellow.
(2009) NSF Career Award.
(2008) American Heart Association Beginning Grant-in-Aid.
(1999) Best Poster, Workshop on Advances in Cellular Imaging, W.M. Keck Center for Cellular Imaging, University of Virgina.
(1999) American Cancer Society Postdoctoral Fellowship.
(1993) Fellowship to attend the Summer Course in Embryology at the Marine Biological Laboratory at Woods Hole, MA.
(1992) Fellowship to present a poster at the Gordon Conference on Theoretical Biology.
(1989 - 1992) Systems in Integrative Biology - NIH National Research Service Award. U.C. Berkeley.
Ph.D., Biophysics, University of California at Berkeley, 1995
M.Sc., Experimental Space Science, York University, 1986
B.S., Physics, University of Illinois at Champaign-Urbana, 1984
Anjum, S., Vijayraghavan, D., Fernandez-Gonzalez, R., Sutherland, A., & Davidson, L. (2025). Inferring active and passive mechanical drivers of epithelial convergent extension. bioRxiv, 6(02-19), 2025.01.28.635314.Cold Spring Harbor Laboratory. doi: 10.1101/2025.01.28.635314.
Yang, J., Hearty, E., Wang, Y., Vijayraghavan, D.S., Walter, T., Anjum, S., Stuckenholz, C., Cheng, Y.W., Balasubramanian, S., Dong, Y., Kwiatkowski, A.V., & Davidson, L.A. (2025). The TissueTractor: A Device for Applying Large Strains to Tissues and Cells for Simultaneous High-Resolution Live Cell Microscopy. Small Methods, e2500136.Wiley. doi: 10.1002/smtd.202500136.
Anjum, S., Turner, L., Atieh, Y., Eisenhoffer, G.T., & Davidson, L.A. (2024). Assessing mechanical agency during apical apoptotic cell extrusion. iScience, 27(11), 111017.Elsevier. doi: 10.1016/j.isci.2024.111017.
Bardhan, A., Brown, W., Albright, S., Tsang, M., Davidson, L.A., & Deiters, A. (2024). Direct Activation of Nucleobases with Small Molecules for the Conditional Control of Antisense Function. Angew Chem Int Ed Engl, 63(17), e202318773.Wiley. doi: 10.1002/anie.202318773.
Brown, W., Davidson, L.A., & Deiters, A. (2024). Expanding the Genetic Code of Xenopus laevis Embryos. ACS Chem Biol, 19(2), 516-525.American Chemical Society (ACS). doi: 10.1021/acschembio.3c00686.
Cheng, Y.W., Anzell, A.R., Morosky, S.A., Schwartze, T.A., Hinck, C.S., Hinck, A.P., Roman, B.L., & Davidson, L.A. (2024). Shear Stress and Sub-Femtomolar Levels of Ligand Synergize to Activate ALK1 Signaling in Endothelial Cells. Cells, 13(3), 285.MDPI. doi: 10.3390/cells13030285.
Davidson, L.A. (2024). Gears of life: A primer on the simple machines that shape the embryo. Curr Top Dev Biol, 160, 87-109.Elsevier. doi: 10.1016/bs.ctdb.2024.05.004.
Yang, J., Hearty, E., Wang, Y., Vijayraghavan, D.S., Walter, T., Anjum, S., Stuckenholz, C., Cheng, Y.W., Balasubramanian, S., Kwiatkowski, A.V., & Davidson, L.A. (2024). The TissueTractor, a device for applying large strains to tissues and cells for simultaneous high-resolution live cell microscopy. bioRxiv, 2024.06.28.600827.Cold Spring Harbor Laboratory. doi: 10.1101/2024.06.28.600827.
Anjum, S., Turner, L., Atieh, Y., Eisenhoffer, G.T., & Davidson, L. (2023). Assessing mechanical agency during apical apoptotic cell extrusion. bioRxiv, 2023.10.26.564227.Cold Spring Harbor Laboratory. doi: 10.1101/2023.10.26.564227.
Cheng, Y.W., Anzell, A.R., Schwartze, T.A., Hinck, C.S., Hinck, A.P., Roman, B.L., & Davidson, L.A. (2023). Shear stress and very low levels of ligand synergize to activate ALK1 signaling in endothelial cells. In bioRxiv. doi: 10.1101/2023.11.01.565194.
Martinson, W.D., McLennan, R., Teddy, J.M., McKinney, M.C., Davidson, L.A., Baker, R.E., Byrne, H.M., Kulesa, P.M., & Maini, P.K. (2023). Dynamic fibronectin assembly and remodeling by leader neural crest cells prevents jamming in collective cell migration. Elife, 12, e83792.eLife. doi: 10.7554/eLife.83792.
Masak, G., & Davidson, L.A. (2023). Constructing the pharyngula: Connecting the primary axial tissues of the head with the posterior axial tissues of the tail. Cells Dev, 176, 203866.Elsevier. doi: 10.1016/j.cdev.2023.203866.
Chu, C.W., & Davidson, L.A. (2022). Chambers for Culturing and Immobilizing Xenopus Embryos and Organotypic Explants for Live Imaging. Cold Spring Harb Protoc, 2022(5), Pdb.prot107649.Cold Spring Harbor Laboratory. doi: 10.1101/pdb.prot107649.
Chu, C.W., & Davidson, L.A. (2022). Myosin-dependent partitioning of junctional Prickle2 toward the anterior vertex during planar polarization of Xenopus neuroectoderm. In bioRxiv. doi: 10.1101/2022.08.26.505384.
Davidson, L.A. (2022). Microsurgical Methods to Isolate and Culture the Early Gastrula Dorsal Marginal Zone. Cold Spring Harb Protoc, 2022(11), Pdb.prot097360. doi: 10.1101/pdb.prot097360.
Davidson, L.A. (2022). Microsurgical Methods to Make the Keller Sandwich Explant and the Dorsal Isolate. Cold Spring Harb Protoc, 2022(11), Pdb.prot097386. doi: 10.1101/pdb.prot097386.
Davidson, L.A. (2022). Microsurgical Manipulations to Isolate Collectively Migrating Mesendoderm. Cold Spring Harb Protoc, 2022(11), Pdb.prot097378. doi: 10.1101/pdb.prot097378.
Davidson, L.A., & Lowery, L.A. (2022). Imaging Methods in Xenopus Cells, Embryos, and Tadpoles. Cold Spring Harb Protoc, 2022(5), Pdb.top105627.Cold Spring Harbor Laboratory. doi: 10.1101/pdb.top105627.
Cervino, A.S., Moretti, B., Stuckenholz, C., Grecco, H.E., Davidson, L.A., & Cirio, M.C. (2021). Furry is required for cell movements during gastrulation and functionally interacts with NDR1. Sci Rep, 11(1), 6607.Springer Nature. doi: 10.1038/s41598-021-86153-x.
Kim, H.Y., & Davidson, L.A. (2021). Xenopus Deep Cell Aggregates: A 3D Tissue Model for Mesenchymal-to-Epithelial Transition. Methods Mol Biol, 2179, 275-287.Springer Nature. doi: 10.1007/978-1-0716-0779-4_21.
Cervino, A.S., Moretti, B., Stuckenholz, C., Grecco, H.E., Davidson, L.A., & Cirio, M.C. (2020). Furry is required for cell movements during gastrulation and functionally interacts with NDR1. In bioRxiv. doi: 10.1101/2020.05.08.083980.
Chu, C.W., Masak, G., Yang, J., & Davidson, L.A. (2020). From biomechanics to mechanobiology: Xenopus provides direct access to the physical principles that shape the embryo. Curr Opin Genet Dev, 63, 71-77.Elsevier. doi: 10.1016/j.gde.2020.05.011.
Ichikawa, T., Stuckenholz, C., & Davidson, L.A. (2020). Non-junctional role of Cadherin3 in cell migration and contact inhibition of locomotion via domain-dependent, opposing regulation of Rac1. Sci Rep, 10(1), 17326.Springer Nature. doi: 10.1038/s41598-020-73862-y.
Kim, H.Y., Jackson, T.R., Stuckenholz, C., & Davidson, L.A. (2020). Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates. Nat Commun, 11(1), 665.Springer Nature. doi: 10.1038/s41467-020-14385-y.
Smith, S.J., Davidson, L.A., & Rebeiz, M. (2020). Evolutionary expansion of apical extracellular matrix is required for the elongation of cells in a novel structure. Elife, 9, e55965.eLife. doi: 10.7554/eLife.55965.
Sonmez, U.M., Cheng, Y.W., Watkins, S.C., Roman, B.L., & Davidson, L.A. (2020). Endothelial cell polarization and orientation to flow in a novel microfluidic multimodal shear stress generator. Lab Chip, 20(23), 4373-4390.Royal Society of Chemistry (RSC). doi: 10.1039/d0lc00738b.
Sonmez, U.M., Cheng, Y.W., Watkins, S.C., Roman, B.L., & Davidson, L.A. (2020). Endothelial Cell Polarization and Orientation to Flow in a Novel Microfluidic Multimodal Shear Stress Generator. In bioRxiv. doi: 10.1101/2020.07.10.197244.
Sonmez, U.M., Wood, A., Justus, K., Jiang, W., Syed-Picard, F., LeDuc, P.R., Kalinski, P., & Davidson, L.A. (2020). Chemotactic Responses of Jurkat Cells in Microfluidic Flow-Free Gradient Chambers. Micromachines (Basel), 11(4), 384.MDPI. doi: 10.3390/mi11040384.
Arnold, T.R., Shawky, J.H., Stephenson, R.E., Dinshaw, K.M., Higashi, T., Huq, F., Davidson, L.A., & Miller, A.L. (2019). Anillin regulates epithelial cell mechanics by structuring the medial-apical actomyosin network. Elife, 8, e39065.eLife. doi: 10.7554/eLife.39065.
Ichikawa, T., Stuckenholz, C., & Davidson, L.A. (2019). Non-junctional Cadherin3 regulates cell migration and contact inhibition of locomotion via domain-dependent opposing regulations of Rac1. In bioRxiv. doi: 10.1101/750752.
Kim, H.Y., Jackson, T.R., Stuckenholz, C., & Davidson, L.A. (2019). Tissue mechanics drives epithelialization, goblet cell regeneration, and restoration of a mucociliated epidermis on the surface of embryonic aggregates. In bioRxiv. doi: 10.1101/696997.
Smith, S.J., Davidson, L.A., & Rebeiz, M. (2019). Expansion of apical extracellular matrix underlies the morphogenesis of a recently evolved structure. 686089.Cold Spring Harbor Laboratory. doi: 10.1101/686089.
Stepien, T.L., Lynch, H.E., Yancey, S.X., Dempsey, L., & Davidson, L.A. (2019). Using a continuum model to decipher the mechanics of embryonic tissue spreading from time-lapse image sequences: An approximate Bayesian computation approach. In Jiang, Y. (Ed.). PLoS One, 14(6), e0218021.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0218021.
Wolff, H.B., Davidson, L.A., & Merks, R.M.H. (2019). Adapting a Plant Tissue Model to Animal Development: Introducing Cell Sliding into VirtualLeaf. Bull Math Biol, 81(8), 3322-3341.Springer Nature. doi: 10.1007/s11538-019-00599-9.
Ingram, G., & Davidson, L. (2018). Editorial: Developmental mechanisms, patterning and evolution (2018). Curr Opin Genet Dev, 51, iii-v.Elsevier. doi: 10.1016/j.gde.2018.11.001.
López-Escobar, B., Caro-Vega, J.M., Vijayraghavan, D.S., Plageman, T.F., Sanchez-Alcazar, J.A., Moreno, R.C., Savery, D., Márquez-Rivas, J., Davidson, L.A., & Ybot-González, P. (2018). The non-canonical Wnt-PCP pathway shapes the mouse caudal neural plate. Development, 145(9), dev157487.The Company of Biologists. doi: 10.1242/dev.157487.
Miller, C.J., Harris, D., Weaver, R., Ermentrout, G.B., & Davidson, L.A. (2018). Emergent mechanics of actomyosin drive punctuated contractions and shape network morphology in the cell cortex. In Umulis, D. (Ed.). PLoS Comput Biol, 14(9), e1006344.Public Library of Science (PLoS). doi: 10.1371/journal.pcbi.1006344.
Shawky, J.H., Balakrishnan, U.L., Stuckenholz, C., & Davidson, L.A. (2018). Multiscale analysis of architecture, cell size and the cell cortex reveals cortical F-actin density and composition are major contributors to mechanical properties during convergent extension. Development, 145(19), dev161281.The Company of Biologists. doi: 10.1242/dev.161281.
Shook, D.R., Kasprowicz, E.M., Davidson, L.A., & Keller, R. (2018). Large, long range tensile forces drive convergence during Xenopus blastopore closure and body axis elongation. Elife, 7, e26944.eLife. doi: 10.7554/eLife.26944.
Shook, D.R., Kasprowicz, E.M., Davidson, L.A., & Keller, R. (2018). Large, long range tensile forces drive convergence during Xenopus blastopore closure and body axis elongation. ELIFE, 7.eLife Sciences Publications, Ltd. doi: 10.7554/eLife.26944.001.
Smith, S.J., Rebeiz, M., & Davidson, L. (2018). From pattern to process: studies at the interface of gene regulatory networks, morphogenesis, and evolution. Curr Opin Genet Dev, 51, 103-110.Elsevier. doi: 10.1016/j.gde.2018.08.004.
Chanet, S., Miller, C.J., Vaishnav, E.D., Ermentrout, B., Davidson, L.A., & Martin, A.C. (2017). Actomyosin meshwork mechanosensing enables tissue shape to orient cell force. Nat Commun, 8(1), 15014.Springer Nature. doi: 10.1038/ncomms15014.
Davidson, L.A. (2017). Mechanical design in embryos: mechanical signalling, robustness and developmental defects. Philos Trans R Soc Lond B Biol Sci, 372(1720), 20150516.The Royal Society. doi: 10.1098/rstb.2015.0516.
Jackson, T.R., Kim, H.Y., Balakrishnan, U.L., Stuckenholz, C., & Davidson, L.A. (2017). Spatiotemporally Controlled Mechanical Cues Drive Progenitor Mesenchymal-to-Epithelial Transition Enabling Proper Heart Formation and Function. Curr Biol, 27(9), 1326-1335.Elsevier. doi: 10.1016/j.cub.2017.03.065.
Kim, H.Y., Jackson, T.R., & Davidson, L.A. (2017). On the role of mechanics in driving mesenchymal-to-epithelial transitions. Semin Cell Dev Biol, 67, 113-122.Elsevier. doi: 10.1016/j.semcdb.2016.05.011.
Shook, D.R., Kasprowicz, E.M., Davidson, L.A., & Keller, R. (2017). Large, long range tensile forces drive convergence during Xenopus blastopore closure and body axis elongation. In bioRxiv. doi: 10.1101/126201.
Stooke-Vaughan, G.A., Davidson, L.A., & Woolner, S. (2017). Xenopus as a model for studies in mechanical stress and cell division. Genesis, 55(1-2).Wiley. doi: 10.1002/dvg.23004.
Vijayraghavan, D.S., & Davidson, L.A. (2017). Mechanics of neurulation: From classical to current perspectives on the physical mechanics that shape, fold, and form the neural tube. Birth Defects Res, 109(2), 153-168.Wiley. doi: 10.1002/bdra.23557.
Adibi, J.J., Zhao, Y., Cartus, A.R., Gupta, P., & Davidson, L.A. (2016). Placental Mechanics in the Zika-Microcephaly Relationship. Cell Host Microbe, 20(1), 9-11.Elsevier. doi: 10.1016/j.chom.2016.06.013.
Holt, B.D., Shawky, J.H., Dahl, K.N., Davidson, L.A., & Islam, M.F. (2016). Distribution of single wall carbon nanotubes in the Xenopus laevis embryo after microinjection. J Appl Toxicol, 36(4), 568-578.Wiley. doi: 10.1002/jat.3255.
Holt, B.D., Shawky, J.H., Dahl, K.N., Davidson, L.A., & Islam, M.F. (2016). Developing Xenopus embryos recover by compacting and expelling single wall carbon nanotubes. J Appl Toxicol, 36(4), 579-585.Wiley. doi: 10.1002/jat.3203.
Feroze, R., Shawky, J.H., von Dassow, M., & Davidson, L.A. (2015). Mechanics of blastopore closure during amphibian gastrulation. Dev Biol, 398(1), 57-67.Elsevier. doi: 10.1016/j.ydbio.2014.11.011.
Hazar, M., Kim, Y.T., Song, J., LeDuc, P.R., Davidson, L.A., & Messner, W.C. (2015). 3D bio-etching of a complex composite-like embryonic tissue. Lab Chip, 15(16), 3293-3299.Royal Society of Chemistry (RSC). doi: 10.1039/c5lc00530b.
McGreevy, E.M., Vijayraghavan, D., Davidson, L.A., & Hildebrand, J.D. (2015). Shroom3 functions downstream of planar cell polarity to regulate myosin II distribution and cellular organization during neural tube closure. Biol Open, 4(2), 186-196.The Company of Biologists. doi: 10.1242/bio.20149589.
Shawky, J.H., & Davidson, L.A. (2015). Tissue mechanics and adhesion during embryo development. Dev Biol, 401(1), 152-164.Elsevier. doi: 10.1016/j.ydbio.2014.12.005.
Song, J., Shawky, J.H., Kim, Y., Hazar, M., LeDuc, P.R., Sitti, M., & Davidson, L.A. (2015). Controlled surface topography regulates collective 3D migration by epithelial-mesenchymal composite embryonic tissues. Biomaterials, 58, 1-9.Elsevier. doi: 10.1016/j.biomaterials.2015.04.021.
Zhou, J., Pal, S., Maiti, S., & Davidson, L.A. (2015). Force production and mechanical accommodation during convergent extension. Development, 142(4), 692-701.The Company of Biologists. doi: 10.1242/dev.116533.
Kim, Y., Hazar, M., Vijayraghavan, D.S., Song, J., Jackson, T.R., Joshi, S.D., Messner, W.C., Davidson, L.A., & LeDuc, P.R. (2014). Mechanochemical actuators of embryonic epithelial contractility. Proc Natl Acad Sci U S A, 111(40), 14366-14371.Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.1405209111.
Kim, Y.T., Hazar, M., Vijayraghavan, D.S., Song, J., Jackson, T.R., Joshi, S.D., Messner, W.C., Davidson, L.A., & LeDuc, P.R. (2014). Mechanochemical actuators of embryonic epithelial contractility. Proceedings of the National Academy of Sciences of the United States of America, 111(40), 14366-14371. doi: 10.1073/pnas.1405209111.
von Dassow, M., Miller, C.J., & Davidson, L.A. (2014). Biomechanics and the thermotolerance of development. In Kreplak, L. (Ed.). PLoS One, 9(4), e95670.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0095670.
Edlund, A.F., Davidson, L.A., & Keller, R.E. (2013). Cell segregation, mixing, and tissue pattern in the spinal cord of the Xenopus laevis neurula. Dev Dyn, 242(10), 1134-1146.Wiley. doi: 10.1002/dvdy.24004.
Kim, H.Y., & Davidson, L.A. (2013). Assembly of chambers for stable long-term imaging of live Xenopus tissue. Cold Spring Harb Protoc, 2013(4), 366-369.Cold Spring Harbor Laboratory. doi: 10.1101/pdb.prot073882.
Kim, H.Y., & Davidson, L.A. (2013). Investigating morphogenesis in Xenopus embryos: imaging strategies, processing, and analysis. Cold Spring Harb Protoc, 2013(4), 298-304.Cold Spring Harbor Laboratory. doi: 10.1101/pdb.top073890.
Kim, H.Y., & Davidson, L.A. (2013). Microsurgical approaches to isolate tissues from Xenopus embryos for imaging morphogenesis. Cold Spring Harb Protoc, 2013(4), 362-365.Cold Spring Harbor Laboratory. doi: 10.1101/pdb.prot073874.
Kim, H.Y., & Davidson, L.A. (2013). Preparation and use of reporter constructs for imaging morphogenesis in Xenopus embryos. Cold Spring Harb Protoc, 2013(4), 359-361.Cold Spring Harbor Laboratory. doi: 10.1101/pdb.prot073866.
Miller, C.J., & Davidson, L.A. (2013). The interplay between cell signalling and mechanics in developmental processes. Nat Rev Genet, 14(10), 733-744.Springer Nature. doi: 10.1038/nrg3513.
Davidson, L.A. (2012). Epithelial machines that shape the embryo. Trends Cell Biol, 22(2), 82-87.Elsevier. doi: 10.1016/j.tcb.2011.10.005.
Davidson, L.A. (2012). No strings attached: new insights into epithelial morphogenesis. BMC Biol, 10(1), 105.Springer Nature. doi: 10.1186/1741-7007-10-105.
Davidson, L.A., & Baum, B. (2012). Making waves: the rise and fall and rise of quantitative developmental biology. Development, 139(17), 3065-3069.The Company of Biologists. doi: 10.1242/dev.080093.
Joshi, S.D., & Davidson, L.A. (2012). Epithelial machines of morphogenesis and their potential application in organ assembly and tissue engineering. Biomech Model Mechanobiol, 11(8), 1109-1121.Springer Nature. doi: 10.1007/s10237-012-0423-6.
Joshi, S.D., Kim, H.Y., & Davidson, L.A. (2012). Microscopy tools for quantifying developmental dynamics in Xenopus embryos. Methods Mol Biol, 917, 477-493.Springer Nature. doi: 10.1007/978-1-61779-992-1_27.
Miller, C.J., Bard Ermentrout, G., & Davidson, L.A. (2012). Rotational model for actin filament alignment by myosin. J Theor Biol, 300, 344-359.Elsevier. doi: 10.1016/j.jtbi.2012.01.036.
Davidson, L.A. (2011). Embryo mechanics: balancing force production with elastic resistance during morphogenesis. Curr Top Dev Biol, 95(Dev. Biol.2712004), 215-241.Elsevier. doi: 10.1016/B978-0-12-385065-2.00007-4.
Kim, H.Y., & Davidson, L.A. (2011). Punctuated actin contractions during convergent extension and their permissive regulation by the non-canonical Wnt-signaling pathway. J Cell Sci, 124(Pt 4), 635-646.The Company of Biologists. doi: 10.1242/jcs.067579.
Kim, Y., Joshi, S.D., Davidson, L.A., LeDuc, P.R., & Messner, W.C. (2011). Dynamic control of 3D chemical profiles with a single 2D microfluidic platform. Lab Chip, 11(13), 2182-2188.Royal Society of Chemistry (RSC). doi: 10.1039/c1lc20077a.
Kim, Y., Joshi, S.D., Messner, W.C., LeDuc, P.R., & Davidson, L.A. (2011). Detection of dynamic spatiotemporal response to periodic chemical stimulation in a Xenopus embryonic tissue. In Chin, W.C. (Ed.). PLoS One, 6(1), e14624.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0014624.
Trier, S.M., & Davidson, L.A. (2011). Quantitative microscopy and imaging tools for the mechanical analysis of morphogenesis. Curr Opin Genet Dev, 21(5), 664-670.Elsevier. doi: 10.1016/j.gde.2011.08.005.
Upadhye, K.V., Candiello, J.E., Davidson, L.A., & Lin, H. (2011). Whole-Cell Electrical Activity Under Direct Mechanical Stimulus by AFM Cantilever Using Planar Patch Clamp Chip Approach. Cell Mol Bioeng, 4(2), 270-280.Springer Nature. doi: 10.1007/s12195-011-0160-4.
von Dassow, M., & Davidson, L.A. (2011). Physics and the canalization of morphogenesis: a grand challenge in organismal biology. Phys Biol, 8(4), 045002.IOP Publishing. doi: 10.1088/1478-3975/8/4/045002.
Davidson, L.A. (2010). The Physical Mechanical Processes that Shape Tissues in the Early Embryo. In Cellular and Biomolecular Mechanics and Mechanobiology. 4, (pp. 71-97).Springer Nature. doi: 10.1007/8415_2010_29.
Davidson, L.A., Joshi, S.D., Kim, H.Y., von Dassow, M., Zhang, L., & Zhou, J. (2010). Emergent morphogenesis: elastic mechanics of a self-deforming tissue. J Biomech, 43(1), 63-70.Elsevier. doi: 10.1016/j.jbiomech.2009.09.010.
Joshi, S.D., & Davidson, L.A. (2010). Live-cell imaging and quantitative analysis of embryonic epithelial cells in Xenopus laevis. J Vis Exp, (39), 1949.MyJove. doi: 10.3791/1949.
Joshi, S.D., von Dassow, M., & Davidson, L.A. (2010). Experimental control of excitable embryonic tissues: three stimuli induce rapid epithelial contraction. Exp Cell Res, 316(1), 103-114.Elsevier. doi: 10.1016/j.yexcr.2009.08.005.
von Dassow, M., Strother, J.A., & Davidson, L.A. (2010). Surprisingly simple mechanical behavior of a complex embryonic tissue. In Kreplak, L. (Ed.). PLoS One, 5(12), e15359.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0015359.
Zhou, J., Kim, H.Y., Wang, J.H.C., & Davidson, L.A. (2010). Macroscopic stiffening of embryonic tissues via microtubules, RhoGEF and the assembly of contractile bundles of actomyosin. Development, 137(16), 2785-2794.The Company of Biologists. doi: 10.1242/dev.045997.
Davidson, L., von Dassow, M., & Zhou, J. (2009). Multi-scale mechanics from molecules to morphogenesis. Int J Biochem Cell Biol, 41(11), 2147-2162.Elsevier. doi: 10.1016/j.biocel.2009.04.015.
Edeling, M.A., Sanker, S., Shima, T., Umasankar, P.K., Höning, S., Kim, H.Y., Davidson, L.A., Watkins, S.C., Tsang, M., Owen, D.J., & Traub, L.M. (2009). Structural requirements for PACSIN/Syndapin operation during zebrafish embryonic notochord development. In Keen, J. (Ed.). PLoS One, 4(12), e8150.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0008150.
Rozario, T., Dzamba, B., Weber, G.F., Davidson, L.A., & DeSimone, D.W. (2009). The physical state of fibronectin matrix differentially regulates morphogenetic movements in vivo. Dev Biol, 327(2), 386-398.Elsevier. doi: 10.1016/j.ydbio.2008.12.025.
von Dassow, M., & Davidson, L.A. (2009). Natural variation in embryo mechanics: gastrulation in Xenopus laevis is highly robust to variation in tissue stiffness. Dev Dyn, 238(1), 2-18.Wiley. doi: 10.1002/dvdy.21809.
Yang, X., Zou, J., Hyde, D.R., Davidson, L.A., & Wei, X. (2009). Stepwise maturation of apicobasal polarity of the neuroepithelium is essential for vertebrate neurulation. J Neurosci, 29(37), 11426-11440.Society for Neuroscience. doi: 10.1523/JNEUROSCI.1880-09.2009.
Zhou, J., Kim, H.Y., & Davidson, L.A. (2009). Actomyosin stiffens the vertebrate embryo during crucial stages of elongation and neural tube closure. Development, 136(4), 677-688.The Company of Biologists. doi: 10.1242/dev.026211.
Davidson, L.A. (2008). Taming the tiger of tissue aggregation: how epithelia control structural assembly of underlying cells. Dev Cell, 14(2), 152-154.Elsevier. doi: 10.1016/j.devcel.2008.01.012.
Davidson, L.A. (2008). Developmental biology. Apoptosis turbocharges epithelial morphogenesis. Science, 321(5896), 1641-1642.American Association for the Advancement of Science (AAAS). doi: 10.1126/science.1164583.
Davidson, L.A. (2008). Integrating morphogenesis with underlying mechanics and cell biology. Curr Top Dev Biol, 81, 113-133.Elsevier. doi: 10.1016/S0070-2153(07)81003-9.
Davidson, L.A., Dzamba, B.D., Keller, R., & Desimone, D.W. (2008). Live imaging of cell protrusive activity, and extracellular matrix assembly and remodeling during morphogenesis in the frog, Xenopus laevis. Dev Dyn, 237(10), 2684-2692.Wiley. doi: 10.1002/dvdy.21600.
Koide, K., Song, F., de Groh, E.D., Garner, A.L., Mitchell, V.D., Davidson, L.A., & Hukriede, N.A. (2008). Scalable and concise synthesis of dichlorofluorescein derivatives displaying tissue permeation in live zebrafish embryos. Chembiochem, 9(2), 214-218.Wiley. doi: 10.1002/cbic.200700565.
Benseñor, L.B., Kan, H.M., Wang, N., Wallrabe, H., Davidson, L.A., Cai, Y., Schafer, D.A., & Bloom, G.S. (2007). IQGAP1 regulates cell motility by linking growth factor signaling to actin assembly. J Cell Sci, 120(Pt 4), 658-669.The Company of Biologists. doi: 10.1242/jcs.03376.
Davidson, L., & Keller, R. (2007). Measuring mechanical properties of embryos and embryonic tissues. 83, 425-439.Elsevier. doi: 10.1016/S0091-679X(07)83018-4.
DeSimone, D.W., Dzamba, B., & Davidson, L.A. (2007). Using Xenopus embryos to investigate integrin function. 426, 403-414.Elsevier. doi: 10.1016/S0076-6879(07)26017-3.
Green, J.B.A., & Davidson, L.A. (2007). Convergent extension and the hexahedral cell. Nat Cell Biol, 9(9), 1010-1015.Springer Nature. doi: 10.1038/ncb438.
von Dassow, M., & Davidson, L.A. (2007). Variation and robustness of the mechanics of gastrulation: the role of tissue mechanical properties during morphogenesis. Birth Defects Res C Embryo Today, 81(4), 253-269.Wiley. doi: 10.1002/bdrc.20108.
Davidson, L.A., Marsden, M., Keller, R., & Desimone, D.W. (2006). Integrin alpha5beta1 and fibronectin regulate polarized cell protrusions required for Xenopus convergence and extension. Curr Biol, 16(9), 833-844.Elsevier. doi: 10.1016/j.cub.2006.03.038.
Stubbs, J.L., Davidson, L., Keller, R., & Kintner, C. (2006). Radial intercalation of ciliated cells during Xenopus skin development. Development, 133(13), 2507-2515.The Company of Biologists. doi: 10.1242/dev.02417.
DeSimone, D.W., Davidson, L., Marsden, M., & Alfandari, D. (2005). The Xenopus embryo as a model system for studies of cell migration. Methods Mol Biol, 294, 235-245.Springer Nature. doi: 10.1385/1-59259-860-9:235.
Goto, T., Davidson, L., Asashima, M., & Keller, R. (2005). Planar cell polarity genes regulate polarized extracellular matrix deposition during frog gastrulation. Curr Biol, 15(8), 787-793.Elsevier. doi: 10.1016/j.cub.2005.03.040.
Constance Lane, M., Davidson, L., & Sheets, M.D. (2004). BMP antagonism by Spemann's organizer regulates rostral-caudal fate of mesoderm. Dev Biol, 275(2), 356-374.Elsevier. doi: 10.1016/j.ydbio.2004.08.012.
Davidson, L.A., Keller, R., & DeSimone, D. (2004). Patterning and tissue movements in a novel explant preparation of the marginal zone of Xenopus laevis. Gene Expr Patterns, 4(4), 457-466.Elsevier. doi: 10.1016/j.modgep.2004.01.001.
Davidson, L.A., Keller, R., & DeSimone, D.W. (2004). Assembly and remodeling of the fibrillar fibronectin extracellular matrix during gastrulation and neurulation in Xenopus laevis. Dev Dyn, 231(4), 888-895.Wiley. doi: 10.1002/dvdy.20217.
Green, J.B.A., Dominguez, I., & Davidson, L.A. (2004). Self-organization of vertebrate mesoderm based on simple boundary conditions. Dev Dyn, 231(3), 576-581.Wiley. doi: 10.1002/dvdy.20163.
Longo, D., Peirce, S.M., Skalak, T.C., Davidson, L., Marsden, M., Dzamba, B., & DeSimone, D.W. (2004). Multicellular computer simulation of morphogenesis: blastocoel roof thinning and matrix assembly in Xenopus laevis. Dev Biol, 271(1), 210-222.Elsevier. doi: 10.1016/j.ydbio.2004.03.021.
Keller, R., Davidson, L.A., & Shook, D.R. (2003). How we are shaped: the biomechanics of gastrulation. Differentiation, 71(3), 171-205.Elsevier. doi: 10.1046/j.1432-0436.2003.710301.x.
Davidson, L.A., Ezin, A.M., & Keller, R. (2002). Embryonic wound healing by apical contraction and ingression in Xenopus laevis. Cell Motil Cytoskeleton, 53(3), 163-176.Wiley. doi: 10.1002/cm.10070.
Davidson, L.A., Hoffstrom, B.G., Keller, R., & DeSimone, D.W. (2002). Mesendoderm extension and mantle closure in Xenopus laevis gastrulation: combined roles for integrin alpha(5)beta(1), fibronectin, and tissue geometry. Dev Biol, 242(2), 109-129.Elsevier. doi: 10.1006/dbio.2002.0537.
Davidson, L.A., & Keller, R.E. (1999). Neural tube closure in Xenopus laevis involves medial migration, directed protrusive activity, cell intercalation and convergent extension. Development, 126(20), 4547-4556.The Company of Biologists. doi: 10.1242/dev.126.20.4547.
Davidson, L.A., Oster, G.F., Keller, R.E., & Koehl, M.A. (1999). Measurements of mechanical properties of the blastula wall reveal which hypothesized mechanisms of primary invagination are physically plausible in the sea urchin Strongylocentrotus purpuratus. Dev Biol, 209(2), 221-238.Elsevier. doi: 10.1006/dbio.1999.9249.
Davidson, L.A., Koehl, M.A., Keller, R., & Oster, G.F. (1995). How do sea urchins invaginate? Using biomechanics to distinguish between mechanisms of primary invagination. Development, 121(7), 2005-2018.The Company of Biologists. doi: 10.1242/dev.121.7.2005.
Kim, Y., Joshi, S.D., LeDuc, P.R., Davidson, L.A., & Messner, W.C. (2010). Probing Multicellular Dynamics in Xenopus Laevis Embryonic Development Using a Mechanical Engineering Based Microfluidic Feedback Approach. In ASME 2010 Summer Bioengineering Conference, Parts A and B, (PARTS A AND B), (pp. 193-194).ASME International. doi: 10.1115/sbc2010-19319.
Joshi, S.D., & Davidson, L.A. (2009). Remote Control of Apical Epithelial Sheet Contraction by Laser Ablation or Nano-Perfusion: Acute Stimulus Triggers Rapid Remodeling of F-Actin Network in Apical Cortex. In ASME 2009 Summer Bioengineering Conference, Parts A and B, (PART B), (pp. 951-952).ASME International. doi: 10.1115/sbc2009-204904.
Longo, D., Peirce, S., Skalak, T., Marsden, M., Davidson, L., Dzamba, B., & DeSimone, D. (2003). Computational Automata Simulation of Blastocoel Roof Thinning in the Xenopu Laevis Embryo. In IEEE Systems and Information Engineering Design Symposium, 2003, (pp. 127-131).Institute of Electrical and Electronics Engineers (IEEE). doi: 10.1109/sieds.2003.158015.
George, S., Evans, D., & Davidson, L. (2002). A biologically inspired programming model for self-healing systems. In Proceedings of the first workshop on Self-healing systems, (pp. 102-104).Association for Computing Machinery (ACM). doi: 10.1145/582128.582149.
Davidson, L. (2001). Biomechanics of morphogenesis: Epithelial bending during sea urchin gastrulation. In American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, 50, (pp. 381-382).
Keller, R., Davidson, L., Edlund, A., Elul, T., Ezin, M., Shook, D., & Skoglund, P. (2000). Mechanisms of convergence and extension by cell intercalation. In Wolpert, L., & Smith, J.C. (Eds.). In Philos Trans R Soc Lond B Biol Sci, 355(1399), (pp. 897-922).The Royal Society.England. doi: 10.1098/rstb.2000.0626.