headshot of Keith Vogt

Keith Vogt

Associate Professor
keith.vogt@pitt.edu
(412) 647-3147
Anesthesiology faculty page

overview

I am an anesthesiologist, biomedical engineer, and physician-scientist who predominantly uses human cognitive neuroscience methods to investigate phenomena relevant to the clinical practice of anesthesiology and perioperative medicine. My long-standing involvement in pain functional neuroimaging research began in 2004 with the optimization work I did as my doctoral research. Using experimental pain as a cognitive experimental task, I collected physiologic data during functional MRI scanning and used these to correct the images for signal fluctuations unrelated to the neural response of interest. During my NRSA postdoctoral fellowship, I began the anesthetic neuroscience work that is ongoing. My current research continues to use functional MRI and complementary neuroscience research techniques to examine the interacting effects in the human brain when the systems for memory encoding, pain processing, and threat response are modulated by the diverse anesthetic and analgesic agents. This has been successfully funded by NIGMS. Through this work, I developed a strong and diverse network of mentors and other collaborators who have helped me to develop further expertise in MRI acquisition and analysis, cognitive neuroscience of pain and memory, and anesthetic pharmacology. More recent additional work has been focused on understanding how auricular stimulation and auriculotherapy affect the brain and may modulate pain perception. I am deeply committed to training future researchers, particularly those at interface of engineering, neuroscience, and medicine. I am committed to fostering an inclusive and supportive laboratory environment where any trainee can reach their maximal potential, through a comprehensive partnership in career development.

about

PhD, Ohio State University, 2009

MD, Ohio State University, 2011

Chelly, J.E., Orebaugh, S.L., Rodosky, M.W., Groff, Y.J., Monroe, A.L., Alimi, D., Sadhasivam, S.K., & Vogt, K.M. (2025). Auriculotherapy for Prolonged Postoperative Pain Management Following Rotator Cuff Surgery: A Randomized, Placebo-Controlled Study. MEDICAL ACUPUNCTURE.Mary Ann Liebert. doi: 10.1089/acu.2024.0061.

Vogt, K.M., Burlew, A.C., Simmons, M.A., Reddy, S.N., Kozdron, C.N., & Ibinson, J.W. (2025). Neural correlates of systemic lidocaine administration in healthy adults measured by functional MRI: a single arm open label study. Br J Anaesth, 134(2), 414-424.Elsevier. doi: 10.1016/j.bja.2024.07.039.

Vogt, K.M., Simmons, M.A., Reddy, S.N., Burlew, A.C., Kozdron, C.N., Lavage, D.R., Wang, S., Pryor, K.O., Shafer, S.L., Ibrahim, T., Aizenstein, H.J., Reder, L.M., Ibinson, J.W., & Fiez, J.A. (2025). Effects of sedative doses of propofol, dexmedetomidine, and fentanyl on memory and pain in healthy young adults: A randomized controlled single-blind crossover study using functional magnetic resonance imaging at 7 Tesla. Anesthesiology.Wolters Kluwer. doi: 10.1097/ALN.0000000000005489.

Chelly, J.E., Holtzman, M.P., Bartlett, D.L., Choudry, H.A., Pingpank, J.F., Zureikat, A.H., Norton, B.E., Sadhasivam, S.K., & Vogt, K.M. (2024). Reduction in postoperative opioid requirement associated with use of the NSS-2® Bridge device, a disposable auriculo-nerve field stimulator, and factors affecting the response in cancer patients undergoing abdominal surgical procedures. J Pain Manag Ther Care, 3(2), 1-9.Pubtexto. doi: 10.36266/jpmtc/119.

Okorie, E.C., Santosa, H., Alter, B.J., Chelly, J.E., Vogt, K.M., & Huppert, T.J. (2024). Ipsilateral stimulation shows somatotopy of thumb and shoulder auricular points on the left primary somatosensory cortex using high-density fNIRS. bioRxiv, 2024.09.16.612477.Cold Spring Harbor Laboratory. doi: 10.1101/2024.09.16.612477.

Schnetz, M.P., Reon, B.J., Ibinson, J.W., Kaynar, M., Mahajan, A., & Vogt, K.M. (2024). Bispectral Index Changes Following Boluses of Commonly Used Intravenous Medications During Volatile Anesthesia Identified From Retrospective Data. Anesth Analg, 138(3), 635-644.Wolters Kluwer. doi: 10.1213/ANE.0000000000006633.

Vogt, K.M., Khan, A., Alter, B.J., Emerick, T.D., Ibinson, J.W., Wasan, A.D., Sadhasivam, S., & Chelly, J.E. (2024). Changes in pain, mood, and functional connectivity following cryo-auriculotherapy in adults with chronic refractory low back pain: An open-label preliminary study. 2024.05.17.24301837.Cold Spring Harbor Laboratory. doi: 10.1101/2024.05.17.24301837.

Whiteleather, J.C., Rosario-Rivera, B., Haruna, A., Munoz-Valencia, A., Ondecko-Ligda, K., Vogt, K.M., & Ibarra, A.J. (2024). Diversity engagement is associated with lower burnout among anesthesia providers. JCA Advances, 1(3-4), 100027.Elsevier. doi: 10.1016/j.jcadva.2024.100027.

Vogt, K.M., Ibinson, J.W., Burlew, A.C., Smith, C.T., Aizenstein, H.J., & Fiez, J.A. (2023). Brain connectivity under light sedation with midazolam and ketamine during task performance and the periodic experience of pain: Examining concordance between different approaches for seed-based connectivity analysis. Brain Imaging Behav, 17(5), 519-529.Springer Nature. doi: 10.1007/s11682-023-00782-6.

Zhang, L., & Vogt, K. (2023). Psychometric and next day electrodermal activity data from an experiment involving midazolam, ketamine, and painful stimulation. Data Brief, 51, 109634.Elsevier. doi: 10.1016/j.dib.2023.109634.

Chelly, J.E., Holtzman, M.P., Bartlett, D.L., Choudry, H.A., Pingpank, J.F., Zureikat, A.H., Norton, B.E., Sadhasivam, S.K., & Vogt, K.M. (2022). Reduction in postoperative opioid requirement associated with use of the NSS-2® Bridge device, a disposable auriculo-nerve field stimulator, and factors affecting the response in cancer patients undergoing abdominal surgical procedures. 2022.02.02.22270328.Cold Spring Harbor Laboratory. doi: 10.1101/2022.02.02.22270328.

Chelly, J.E., Orebaugh, S.L., Rodosky, M.W., Groff, Y.J., Norton, B.E., Monroe, A.L., Alimi, D., Sadhasivam, S.K., & Vogt, K.M. (2022). The Effect of Cryo-auriculotherapy on Post-Operative Pain Management following Rotator Cuff Surgery: A Randomized, Placebo-Controlled Study. In medRxiv. doi: 10.1101/2022.02.05.22270330.

Mathis, M.R., Schonberger, R.B., Whitlock, E.L., Vogt, K.M., Lagorio, J.E., Jones, K.A., Conroy, J.M., & Kheterpal, S. (2022). Opportunities Beyond the Anesthesiology Department: Broader Impact Through Broader Thinking. Anesth Analg, 134(2), 242-252.Wolters Kluwer. doi: 10.1213/ANE.0000000000005428.

Norton, C.M., Ibinson, J.W., Pcola, S.J., Popov, V., Tremel, J.J., Reder, L.M., Fiez, J.A., & Vogt, K.M. (2022). Neutral auditory words immediately followed by painful electric shock may show reduced next-day recollection. Exp Brain Res, 240(11), 2939-2951.Springer Nature. doi: 10.1007/s00221-022-06467-8.

Vogt, K.M., & Pryor, K.O. (2022). Anesthesia and the neurobiology of fear and posttraumatic stress disorder. Curr Opin Anaesthesiol, 35(5), 593-599.Wolters Kluwer. doi: 10.1097/ACO.0000000000001176.

Vogt, K.M., Citro, A.T., Adams, P.S., Metro, D.G., & Sakai, T. (2022). Early immersion in a dedicated one-month Anesthesiology Professional Practice rotation for Post-Graduate Year-1 interns is associated with an increase in scholarly activity during residency. J Clin Anesth, 76, 110566.Elsevier. doi: 10.1016/j.jclinane.2021.110566.

Vlisides, P.E., Vogt, K.M., Pal, D., Schnell, E., Armstead, W.M., Brambrink, A.M., Kuo, P., Nelson, P., Vacas, S., Goettel, N., Aglio, L.S., Farag, E., Gorji, R., García, P.S., & Koerner, I.P. (2021). Roadmap for Conducting Neuroscience Research in the COVID-19 Era and Beyond: Recommendations From the SNACC Research Committee. J Neurosurg Anesthesiol, 33(2), 100-106.Wolters Kluwer. doi: 10.1097/ANA.0000000000000758.

Citro, A.T., Norton, C.M., Pcola, S.J., & Vogt, K.M. (2020). Psychometric and electrodermal activity data from an experimental paradigm of memory encoding with some items periodically followed by painful electric shock. Data Brief, 31, 105669.Elsevier. doi: 10.1016/j.dib.2020.105669.

Deis, A.S., Schnetz, M.P., Ibinson, J.W., & Vogt, K.M. (2020). Retrospective analysis of cases of intraoperative awareness in a large multi-hospital health system reported in the early postoperative period. BMC Anesthesiol, 20(1), 62.Springer Nature. doi: 10.1186/s12871-020-00974-3.

Deis, A.S., Schnetz, M.P., Ibinson, J.W., & Vogt, K.M. (2020). Retrospective analysis of cases of intraoperative awareness in a large multi-hospital health system reported in the early postoperative period. Research Square Platform. doi: 10.21203/rs.2.12303/v4.

Deis, A.S., Schnetz, M.P., Ibinson, J.W., & Vogt, K.M. (2020). Retrospective analysis of cases of intraoperative awareness in a large multi-hospital health system reported in the early postoperative period. Research Square Platform. doi: 10.21203/rs.2.12303/v5.

Deis, A.S., Schnetz, M.P., Ibinson, J.W., & Vogt, K.M. (2020). Retrospective analysis of cases of intraoperative awareness in a large multi-hospital health system reported in the early postoperative period. Research Square Platform. doi: 10.21203/rs.2.12303/v3.

Norton, C.M., Ibinson, J.W., Pcola, S.J., Popov, V., Tremel, J.J., Reder, L.M., Fiez, J.A., & Vogt, K.M. (2020). Neutral auditory words immediately followed by painful electric shock show reduced next-day recollection. 2020.02.24.963165.Cold Spring Harbor Laboratory. doi: 10.1101/2020.02.24.963165.

Ungerman, E.A., Vogt, K.M., Sakai, T., Metro, D.G., & Adams, P.S. (2020). Wellness Principles Correlate With More Favorable Burnout Scores in Junior Anesthesiology Residents. J Educ Perioper Med, 22(1), E636.Society for Education in Anesthesia. doi: 10.46374/volxxii-issue1-ungerman.

Adams, D.R., Vogt, K.M., Norton, C.M., & Metro, D.G. (2019). Financial Incentive, in Place of Nonclinical Time, Increases Faculty Involvement and Improves Resident Didactic Evaluation Scores in an Anesthesiology Residency Training Program. J Educ Perioper Med, 21(4), E630.Society for Education in Anesthesia. doi: 10.46374/volxxi-issue4-adams.

Deis, A.S., Schnetz, M.P., Ibinson, J.W., & Vogt, K.M. (2019). Retrospective analysis of cases of intraoperative awareness in a large multi-hospital health system reported in the early postoperative period. Research Square Platform. doi: 10.21203/rs.2.12303/v2.

Deis, A.S., Schnetz, M.P., Ibinson, J.W., & Vogt, K.M. (2019). Title: Retrospective analysis of reported cases of intraoperative awareness in a large multi-hospital health system. Research Square Platform. doi: 10.21203/rs.2.12303/v1.

Schnetz, M.P., Hochheiser, H.S., Danks, D.J., Landsittel, D.P., Vogt, K.M., Ibinson, J.W., Whitehurst, S.L., McDermott, S.P., Duque, M.G., & Kaynar, A.M. (2019). The triple variable index combines information generated over time from common monitoring variables to identify patients expressing distinct patterns of intraoperative physiology. BMC Med Res Methodol, 19(1), 17.Springer Nature. doi: 10.1186/s12874-019-0660-9.

Vogt, K.M., Norton, C.M., Speer, L.E., Tremel, J.J., Ibinson, J.W., Reder, L.M., & Fiez, J.A. (2019). Memory for non-painful auditory items is influenced by whether they are experienced in a context involving painful electrical stimulation. Exp Brain Res, 237(7), 1615-1627.Springer Nature. doi: 10.1007/s00221-019-05534-x.

Becker, C.J., Vogt, K.M., & Ibinson, J.W. (2018). Human posterior insula to posterior cingulate functional connectivity is related to the subjective intensity of acute pain. 246959.Cold Spring Harbor Laboratory. doi: 10.1101/246959.

Becker, C.J., Vogt, K.M., & Ibinson, J.W. (2018). Functional MRI in Pain Management. In Functional MRI, Bandt, S.K., & Spencer, D.D. (Eds.). (pp. 158-173).Oxford University Press (OUP). doi: 10.1093/med/9780190297763.003.0009.

Vogt, K.M., Norton, C.M., Speer, L.E., Tremel, J.J., Ibinson, J.W., Reder, L.M., & Fiez, J.A. (2018). Memory for non-painful auditory items is influenced by whether they are experienced in a context involving painful electrical stimulation. 341891.Cold Spring Harbor Laboratory. doi: 10.1101/341891.

Ibinson, J.W., & Vogt, K.M. (2017). 60 Statistics. In Smith's Anesthesia for Infants and Children. (pp. 1354-1364.e1).Elsevier. doi: 10.1016/b978-0-323-34125-7.00060-7.

Manelis, A., Popov, V., Paynter, C., Walsh, M., Wheeler, M.E., Vogt, K.M., & Reder, L.M. (2017). Cortical Networks Involved in Memory for Temporal Order. J Cogn Neurosci, 29(7), 1253-1266.MIT Press. doi: 10.1162/jocn_a_01123.

Vogt, K.M., Becker, C.J., Wasan, A.D., & Ibinson, J.W. (2016). Human Posterior Insula Functional Connectivity Differs Between Electrical Pain and the Resting State. Brain Connect, 6(10), 786-794.Mary Ann Liebert. doi: 10.1089/brain.2016.0436.

Ibinson, J.W., Vogt, K.M., Taylor, K.B., Dua, S.B., Becker, C.J., Loggia, M., & Wasan, A.D. (2015). Optimizing and Interpreting Insular Functional Connectivity Maps Obtained During Acute Experimental Pain: The Effects of Global Signal and Task Paradigm Regression. Brain Connect, 5(10), 649-657.Mary Ann Liebert. doi: 10.1089/brain.2015.0354.

Ibinson, J.W., & Vogt, K.M. (2013). Pain does not follow the boxcar model: temporal dynamics of the BOLD fMRI signal during constant current painful electric nerve stimulation. J Pain, 14(12), 1611-1619.Elsevier. doi: 10.1016/j.jpain.2013.08.004.

Vogt, K.M., Ibinson, J.W., Schmalbrock, P., & Small, R.H. (2011). Comparison between end-tidal CO₂ and respiration volume per time for detecting BOLD signal fluctuations during paced hyperventilation. Magn Reson Imaging, 29(9), 1186-1194.Elsevier. doi: 10.1016/j.mri.2011.07.011.

Vogt, K.M., Ibinson, J.W., Schmalbrock, P., & Small, R.H. (2011). The impact of physiologic noise correction applied to functional MRI of pain at 1.5 and 3.0 T. Magn Reson Imaging, 29(6), 819-826.Elsevier. doi: 10.1016/j.mri.2011.02.017.

Vogt, K.M., Kauh, C.Y., Holder, D.M., & DePhilip, R.M. (2011). Fluoroscopic angiography in the gross anatomy dissection laboratory: visualizing the aortic arch and its branches in a cadaver. Clin Anat, 24(2), 253-257.Wiley. doi: 10.1002/ca.21080.

Vogt, K.M., Kauh, C.Y., Holder, D.M., & DePhilip, R.M. (2011). Reply: Aberrant Right Subclavian Artery and Fluoroscopy in the Dissection Laboratory. CLINICAL ANATOMY, 24(4), 509.Wiley. doi: 10.1002/ca.21132.

Al Ta'ani, O., Subramaniam, K., Al Qudah, A., Gorijala, V.K., Sadhasivam, S., Vogt, K., Nadkarni, N., Kiselevskaya, V., & Thirumala, P. (2023). The Use of Intraoperative Neuromonitoring to Predict Post-Operative Delirium in Patients Undergoing Cardiac Surgery: A Retrospective Study. In NEUROLOGY, 100(17).Wolters Kluwer. doi: 10.1212/WNL.0000000000202680.

Reon, B., Schnetz, M., & Vogt, K. (2023). Intraoperative Triple Low and Low MAP-BIS States are Associated with Post-Operative ICU Delirium: A Retrospective Analysis. In ANESTHESIA AND ANALGESIA, 136, (pp. 809-812).

Tallapaneni, P., Al Ta'ani, O., Subramaniam, K., Gorijala, V.K., Al Qudah, A., Sadhasivam, S., Vogt, K., Nadkarni, N., Kiselevskaya, V., & Thirumala, P. (2023). The Use of Intraoperative Neuromonitoring to Predict Post-Operative Delirium in Patients Undergoing Major Cardiac Surgery: A Retrospective Study. In ANESTHESIA AND ANALGESIA, 136, (p. 997).

Vogt, K., Burlew, A., Reddy, S.N., Kozdron, C., Wang, S., Shafer, S., Aizenstein, H., Ibinson, J., & Fiez, J. (2023). Resting-state Functional Connectivity Changes with Propofol, Dexmedetomidine, and Fentanyl in Healthy Young Adults: A Randomized Placebo-Controlled Comparative Study Using 7 Tesla MRI. In ANESTHESIA AND ANALGESIA, 136, (pp. 591-593).

Vogt, K., Reddy, S.N., Kozdron, C., Burlew, A., Shafer, S., Aizenstein, H., Reder, L., Ibinson, J., & Fiez, J. (2023). Modulation of Human Memory and Pain by Diverse Anesthetic Agents: A Randomized Placebo-Controlled Crossover 7 Tesla Functional MRI Study in Healthy Young Adults. In ANESTHESIA AND ANALGESIA, 136, (pp. 578-580).

Reon, B., Vogt, K.M., & Schnetz, M. (2022). Association of Post-operative ICU Delirium and Intraoperative Triple Low State. In ANESTHESIA AND ANALGESIA, 134, (pp. 984-985).

Wang, S.S., & Vogt, K.M. (2022). Performance in distinct domains of cognition may be differentially impacted by light sedation with diverse anesthetics. In ANESTHESIA AND ANALGESIA, 134, (pp. 596-598).

Deis, A., & Vogt, K.M. (2021). A systematic review of provider and patient reported cases of awareness under general anesthesia: Analysis of data from a multi-hospital academic health system. In ANESTHESIA AND ANALGESIA, 132(5S_SUPPL), (pp. 665-666).

Vogt, K.M., Ibinson, J.W., Smith, C.T., Citro, A.T., Norton, C.M., Karim, H.T., Popov, V., Mahajan, A., Aizenstein, H.J., Reder, L.M., & Fiez, J.A. (2021). Midazolam and Ketamine Produce Distinct Neural Changes in Memory, Pain, and Fear Networks during Pain. In Anesthesiology, 135(1), (pp. 69-82).Wolters Kluwer.United States. doi: 10.1097/ALN.0000000000003774.

Vogt, K.M., Smith, C.T., Ibinson, J.W., & Fiez, J. (2021). Whole-brain network connectivity changes with midazolam sedation during task performance and periodic pain: A functional MRI study in healthy young adults. In ANESTHESIA AND ANALGESIA, 132(5S_SUPPL), (pp. 520-523).

Schnetz, M.P., Ibinson, J.W., Mahajan, A., Kaynar, A.M., & Vogt, K.M. (2020). Isolated intravenous anesthetic doses have small effects on BIS index during volatilebased anesthesia in surgical patients: A singleinstitution retrospective study. In ANESTHESIA AND ANALGESIA, 130, (pp. 741-743).

Vogt, K.M., Adams, P., Citro, A., Metro, D., & Sakai, T. (2020). Participation in a dedicated one-month Anesthesiology Professional Practice rotation as a PGY1 is associated with increased scholarly productivity during anesthesiology residency. In ANESTHESIA AND ANALGESIA, 130, (pp. 277-278).

Vogt, K.M., Smith, C.T., Mahajan, A., Ibinson, J.W., & Fiez, J. (2020). Neural correlates of memory formation during periodic acute pain with low-dose midazolam and ketamine: A randomized within-subject crossover functional MRI study in healthy young adult subjects. In ANESTHESIA AND ANALGESIA, 130, (pp. 397-399).

Schnetz, M.P., Dasgupta, P., Landsittel, D., Hochheiser, H., Vogt, K.M., Ibinson, J.W., Whitehurst, S., Mahajan, A., Danks, D., & Kaynar, A.M. (2019). RESPONSE TO INHALED ANESTHETICS MEASURED BY THE TRIPLE VARIABLE INDEX REVEALS POPULATION-SPECIFIC PATTERNS OF INTRAOPERATIVE HYPOTENSION EXPOSURE. In ANESTHESIA AND ANALGESIA, 128, (pp. 929-931).

Schnetz, M.P., Danks, D., Landsittel, D., Vogt, K.M., Ibinson, J.W., Whitehurst, S., & Kaynar, A.M. (2018). THE TRIPLE VARIABLE INDEX REVEALS SHARED PATTERNS OF PHYSIOLOGY THAT BROADEN THE UTILITY OF COMMON INTRAOPERATIVE MONITORING SYSTEMS TO CAPTURE RISK INFORMATION NOT IDENTIFIED BY ESTABLISHED MODELS. In ANESTHESIA AND ANALGESIA, 126(4), (pp. 667-670).

Smith, C.T., Vogt, K.M., & Ibinson, J.W. (2018). MIDAZOLAM SEDATION DURING THE PERIODIC EXPERIENCE OF PAIN DECREASES FUNCTIONAL CONNECTIVITY BOTH WITHIN AND BETWEEN BRAIN SYSTEMS FOR PAIN PROCESSING AND MEMORY ENCODING. In ANESTHESIA AND ANALGESIA, 126(4), (pp. 345-346).

Becker, C., Vogt, K., & Ibinson, J. (2017). Posterior cingulate connectivity changes during acute and chronic pain. In JOURNAL OF PAIN, 18(4), (p. S56).Elsevier. doi: 10.1016/j.jpain.2017.02.219.

Becker, C.J., Vogt, K.M., & Ibinson, J.W. (2016). VALIDATION OF INSULA CONNECTIVITY CHANGES DURING PAIN. In ANESTHESIA AND ANALGESIA, 122.

Vogt, K.M., Ibinson, J.W., Tremel, J., Reder, L.M., & Fiez, J.A. (2016). ACUTE EXPERIMENTAL PAIN AFFECTS LONG-TERM MEMORY OF AUDITORY CUES PRESENTED DURING SEDATION WITH DEXMEDETOMIDINE AND MIDAZOLAM. In ANESTHESIA AND ANALGESIA, 122.

Becker, C., Vogt, K., & Ibinson, J. (2015). The insula's functional connectivity to the default mode network is uniquely altered by pain perception. In JOURNAL OF PAIN, 16(4), (p. S54).Elsevier. doi: 10.1016/j.jpain.2015.01.231.

Ibinson, J., Gach, M., & Vogt, K. (2015). A comparison of the BOLD and ASL temporal responses during functional imaging of pain. In JOURNAL OF PAIN, 16(4), (p. S53).Elsevier. doi: 10.1016/j.jpain.2015.01.226.

Ibinson, J., & Vogt, K. (2014). Effect of anti-correlations on statistical comparisons between pain task and resting fcMRI datasets. In JOURNAL OF PAIN, 15(4), (p. S58).Elsevier. doi: 10.1016/j.jpain.2014.01.239.

Ibinson, J., & Vogt, K. (2014). fcMRI maps during pain tasks vary based on the inclusion of paradigm modeling in analysis. In JOURNAL OF PAIN, 15(4), (p. S57).Elsevier. doi: 10.1016/j.jpain.2014.01.235.

Vogt, K.M., & Ibinson, J.W. (2014). THE POSTERIOR INSULA REVEALS PAIN VS REST FUNCTIONAL CONNECTIVITY DIFFERENCES NOT PRESENT WITH THE ANTERIOR INSULA. In ANESTHESIA AND ANALGESIA, 118, (p. S202).