headshot of Jonathan Vande Geest

Jonathan Vande Geest

Professor
Professor and Director of PhD Admissions
Soft Tissue Biomechanics Laboratory Bioengineering Department

about

PhD, Bioengineering, University of Pittsburgh, 2005

BS, Biomedical Engineering, University of Iowa, 2000

Behrangzade, A., Ye, S.H., Maestas Jr., D.R., Wagner, W.R., & Geest, J.P.V. (2024). Improving the hemocompatibility of a porohyperelastic layered vascular graft using luminal reversal microflows. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 157, 106638.Elsevier. doi: 10.1016/j.jmbbm.2024.106638.

Furdella, K.J., Higuchi, S., Kim, K., Doetschman, T., Wagner, W.R., & Vande Geest, J.P. (2022). Acute Elution of TGFβ2 Affects the Smooth Muscle Cells in a Compliance-Matched Vascular Graft. TISSUE ENGINEERING PART A, 28(13-14), 640-650.Mary Ann Liebert. doi: 10.1089/ten.tea.2021.0161.

Kollech, H.G., Chao, M.R., Stark, A.C., German, R.Z., Paniello, R.C., Christensen, M.B., Barkmeier-Kraemer, J.M., & Geest, J.P.V. (2022). Extracellular matrix deformations of the porcine recurrent laryngeal nerve in response to hydrostatic pressure. ACTA BIOMATERIALIA, 153, 364-373.Elsevier. doi: 10.1016/j.actbio.2022.09.039.

Furdella, K.J., Higuchi, S., Behrangzade, A., Kim, K., Wagner, W.R., & Vande Geest, J.P. (2021). In-vivo assessment of a tissue engineered vascular graft computationally optimized for target vessel compliance. ACTA BIOMATERIALIA, 123, 298-311.Elsevier. doi: 10.1016/j.actbio.2020.12.058.

Liou, J.J., Drewry, M.D., Sweeney, A., Brown, B.N., & Vande Geest, J.P. (2020). Decellularizing the Porcine Optic Nerve Head: Toward a Model to Study the Mechanobiology of Glaucoma. TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 9(8), 17.Association for Research in Vision and Ophthalmology (ARVO). doi: 10.1167/tvst.9.8.17.

Liou, J.J., Shoemaker, J.E., & Vande Geest, J.P. (2020). Mechanobiology of the Optic Nerve Head in Primary Open-Angle Glaucoma. In Mechanobiology. (pp. 47-64).Elsevier. doi: 10.1016/b978-0-12-817931-4.00003-0.

Ardila, D.C., Liou, J.J., Maestas, D., Slepian, M.J., Badowski, M., Wagner, W.R., Harris, D., & Vande Geest, J.P. (2019). Surface Modification of Electrospun Scaffolds for Endothelialization of Tissue-Engineered Vascular Grafts Using Human Cord Blood-Derived Endothelial Cells. JOURNAL OF CLINICAL MEDICINE, 8(2), 185.MDPI. doi: 10.3390/jcm8020185.

Ardila, D.C., Tamimi, E., Doetschman, T., Wagner, W.R., & Geest, V.J.P. (2019). Modulating smooth muscle cell response by the release of TGFβ2 from tubular scaffolds for vascular tissue engineering. JOURNAL OF CONTROLLED RELEASE, 299, 44-52.Elsevier. doi: 10.1016/j.jconrel.2019.02.024.

Behkam, R., Kollech, H.G., Jana, A., Hill, A., Danford, F., Howerton, S., Ram, S., Rodriguez, J.J., Utzinger, U., Girkin, C.A., & Vande Geest, J.P. (2019). Racioethnic differences in the biomechanical response of the lamina cribrosa. ACTA BIOMATERIALIA, 88, 131-140.Elsevier. doi: 10.1016/j.actbio.2019.02.028.

Kollech, H.G., Ayyalasomayajula, A., Behkam, R., Tamimi, E., Furdella, K., Drewry, M., & Geest, J.P.V. (2019). A subdomain method for mapping the heterogeneous mechanical properties of the human posterior Sclera. Frontiers in Bioengineering and Biotechnology, 7(MAY). doi: 10.3389/fbioe.2019.129.

Kollech, H.G., Ayyalasomayajula, A., Behkam, R., Tamimi, E., Furdella, K., Drewry, M., & Vande Geest, J.P. (2019). A Subdomain Method for Mapping the Heterogeneous Mechanical Properties of the Human Posterior Sclera. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 7, 129.Frontiers. doi: 10.3389/fbioe.2019.00129.

Tamimi, E.A., Ardila, D.C., Ensley, B.D., Kellar, R.S., & Geest, J.V. (2019). Computationally optimizing the compliance of multilayered biomimetic tissue engineered vascular grafts. Journal of Biomechanical Engineering, 141(6), 0610031-06100314.ASME International. doi: 10.1115/1.4042902.

Ram, S., Danford, F., Howerton, S., Rodriguez, J.J., & Vande Geest, J.P. (2018). Three-Dimensional Segmentation of the Ex-Vivo Anterior Lamina Cribrosa From Second-Harmonic Imaging Microscopy. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 65(7), 1617-1629.Institute of Electrical and Electronics Engineers (IEEE). doi: 10.1109/TBME.2017.2674521.

Behkam, R., Roberts, K.E., Bierhals, A.J., Jacobs, M.E., Edgar, J.D., Paniello, R.C., Woodson, G., Geest, J.P.V., & Barkmeier-Kraemer, J.M. (2017). Aortic arch compliance and idiopathic unilateral vocal fold paralysis. JOURNAL OF APPLIED PHYSIOLOGY, 123(2), 303-309.American Physiological Society. doi: 10.1152/japplphysiol.00239.2017.

Furdella, K.J., Witte, R.S., & Vande Geest, J.P. (2017). Tracking delivery of a drug surrogate in the porcine heart using photoacoustic imaging and spectroscopy. JOURNAL OF BIOMEDICAL OPTICS, 22(4), 041016.SPIE, the international society for optics and photonics. doi: 10.1117/1.JBO.22.4.041016.

Tamimi, E.A., Pyne, J.D., Muli, D.K., Axman, K.E., Howerton, S.J., Davis, M.R., Girkin, C.A., & Vande Geest, J.P. (2017). Racioethnic Differences in Human Posterior Scleral and Optic Nerve Stump Deformation. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 58(10), 4235-4246.Association for Research in Vision and Ophthalmology (ARVO). doi: 10.1167/iovs.17-22141.

Armstrong, M.H., Tepole, A.B., Kuhl, E., Simon, B.R., & Vande Geest, J.P. (2016). A Finite Element Model for Mixed Porohyperelasticity with Transport, Swelling, and Growth. In Aliseda, A. (Ed.). PLOS ONE, 11(4), e0152806.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0152806.

Ayyalasomayajula, A., Park, R.I., Simon, B.R., & Vande Geest, J.P. (2016). A porohyperelastic finite element model of the eye: the influence of stiffness and permeability on intraocular pressure and optic nerve head biomechanics. COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING, 19(6), 591-602.Taylor & Francis. doi: 10.1080/10255842.2015.1052417.

Harrison, S., Tamimi, E., Uhlorn, J., Leach, T., & Vande Geest, J.P. (2016). Computationally Optimizing the Compliance of a Biopolymer Based Tissue Engineered Vascular Graft. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 138(1), 014505.ASME International. doi: 10.1115/1.4032060.

Haskett, D.G., Maestas, D., Howerton, S.J., Smith, T., Ardila, D.C., Doetschman, T., Utzinger, U., McGrath, D., McIntyre, J.O., & Vande Geest, J.P. (2016). 2-Photon Characterization of Optical Proteolytic Beacons for Imaging Changes in Matrix-Metalloprotease Activity in a Mouse Model of Aneurysm. MICROSCOPY AND MICROANALYSIS, 22(2), 349-360.Oxford University Press (OUP). doi: 10.1017/S1431927616000088.

Tamimi, E., Ardila, D.C., Haskett, D.G., Doetschman, T., Slepian, M.J., Kellar, R.S., & Vande Geest, J.P. (2016). Biomechanical Comparison of Glutaraldehyde-Crosslinked Gelatin Fibrinogen Electrospun Scaffolds to Porcine Coronary Arteries. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 138(1), 011001.ASME International. doi: 10.1115/1.4031847.

Ardila, D.C., Tamimi, E., Danford, F.L., Haskett, D.G., Kellar, R.S., Doetschman, T., & Vande Geest, J.P. (2015). TGFβ2 differentially modulates smooth muscle cell proliferation and migration in electrospun gelatin-fibrinogen constructs. BIOMATERIALS, 37, 164-173.Elsevier. doi: 10.1016/j.biomaterials.2014.10.021.

Williams, M.J., Ayylasomayajula, A., Behkam, R., Bierhals, A.J., Jacobs, M.E., Edgar, J.D., Paniello, R.C., Barkmeier-Kraemer, J.M., & Geest, J.P.V. (2015). A computational study of the role of the aortic arch in idiopathic unilateral vocal-fold paralysis. JOURNAL OF APPLIED PHYSIOLOGY, 118(4), 465-474.American Physiological Society. doi: 10.1152/japplphysiol.00638.2014.

Harper, J.L., Simon, B.R., & Geest, J.P.V. (2014). A one-dimensional mixed porohyperelastic transport swelling finite element model with growth. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 29, 663-675.Elsevier. doi: 10.1016/j.jmbbm.2013.04.019.

Pyne, J.D., Genovese, K., Casaletto, L., & Vande Geest, J.P. (2014). Sequential-Digital Image Correlation for Mapping Human Posterior Sclera and Optic Nerve Head Deformation. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 136(2), 021002.ASME International. doi: 10.1115/1.4026224.

Williams, M.J., Utzinger, U., Barkmeier-Kraemer, J.M., & Vande Geest, J.P. (2014). Differences in the Microstructure and Biomechanical Properties of the Recurrent Laryngeal Nerve as a Function of Age and Location. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 136(8), 081008.ASME International. doi: 10.1115/1.4027682.

Danford, F.L., Yan, D., Dreier, R.A., Cahir, T.M., Girkin, C.A., & Vande Geest, J.P. (2013). Differences in the Region- and Depth-Dependent Microstructural Organization in Normal Versus Glaucomatous Human Posterior Sclerae. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 54(13), 7922-7932.Association for Research in Vision and Ophthalmology (ARVO). doi: 10.1167/iovs.13-12262.

Haskett, D., Azhar, M., Utzinger, U., & Geest, J.P.V. (2013). Progressive alterations in microstructural organization and biomechanical response in the ApoE mouse model of aneurysm. Biomatter, 3(3), e24648.Taylor & Francis. doi: 10.4161/biom.24648.

Haskett, D., Johnson, G., Zhou, A., Utzinger, U., & Vande Geest, J. (2013). Erratum to: Microstructural and biomechanical alterations of the human aorta as a function of age and location (vol 12, pg 413, 2013). BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 12(2), 413-414.Springer Nature. doi: 10.1007/s10237-012-0415-6.

Keyes, J.T., Lockwood, D.R., Simon, B.R., & Vande Geest, J.P. (2013). Deformationally dependent fluid transport properties of porcine coronary arteries based on location in the coronary vasculature. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 17, 296-306.Elsevier. doi: 10.1016/j.jmbbm.2012.10.002.

Keyes, J.T., Lockwood, D.R., Utzinger, U., Montilla, L.G., Witte, R.S., & Vande Geest, J.P. (2013). Comparisons of Planar and Tubular Biaxial Tensile Testing Protocols of the Same Porcine Coronary Arteries. ANNALS OF BIOMEDICAL ENGINEERING, 41(7), 1579-1591.Springer Nature. doi: 10.1007/s10439-012-0679-0.

Keyes, J.T., Simon, B.R., & Geest, J.P.V. (2013). A Finite Element Study on Variations in Mass Transport in Stented Porcine Coronary Arteries Based on Location in the Coronary Arterial Tree. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 135(6), 061008.ASME International. doi: 10.1115/1.4024137.

Keyes, J.T., Simon, B.R., & Vande Geest, J.P. (2013). Location-Dependent Coronary Artery Diffusive and Convective Mass Transport Properties of a Lipophilic Drug Surrogate Measured Using Nonlinear Microscopy. PHARMACEUTICAL RESEARCH, 30(4), 1147-1160.Springer Nature. doi: 10.1007/s11095-012-0950-y.

Warren, P.D., Sycks, D.G., McGrath, D.V., & Vande Geest, J.P. (2013). Modeling the microstructurally dependent mechanical properties of poly(ester-urethane-urea)s. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 101(12), 3382-3387.Wiley. doi: 10.1002/jbm.a.34641.

Haskett, D., Doyle, J.J., Gard, C., Chen, H., Ball, C., Estabrook, M.A., Encinas, A.C., Dietz, H.C., Utzinger, U., Vande Geest, J.P., & Azhar, M. (2012). Altered tissue behavior of a non-aneurysmal descending thoracic aorta in the mouse model of Marfan syndrome. CELL AND TISSUE RESEARCH, 347(1), 267-277.Springer Nature. doi: 10.1007/s00441-011-1270-y.

Haskett, D., Speicher, E., Fouts, M., Larson, D., Azhar, M., Utzinger, U., & Geest, J.V. (2012). The effects of angiotensin II on the coupled microstructural and biomechanical response of C57BL/6 mouse aorta. JOURNAL OF BIOMECHANICS, 45(5), 772-779.Elsevier. doi: 10.1016/j.jbiomech.2011.11.017.

Holmes, J.W., & Geest, J.P.V. (2012). Cardiovascular solid mechanics grows and remodels. JOURNAL OF BIOMECHANICS, 45(5), 727.Elsevier. doi: 10.1016/j.jbiomech.2011.11.011.

Ashton, J.H., Ayyalasomayajula, A., Simon, B.R., & Geest, J.P.V. (2011). Wall Stress Reduction in Abdominal Aortic Aneurysms as a Result of Polymeric Endoaortic Paving. ANNALS OF BIOMEDICAL ENGINEERING, 39(6), 1680-1689.Springer Nature. doi: 10.1007/s10439-011-0271-z.

Ashton, J.H., Mertz, J.A.M., Harper, J.L., Slepian, M.J., Mills, J.L., McGrath, D.V., & Vande Geest, J.P. (2011). Polymeric endoaortic paving: Mechanical, thermoforming, and degradation properties of polycaprolactone/polyurethane blends for cardiovascular applications. ACTA BIOMATERIALIA, 7(1), 287-294.Elsevier. doi: 10.1016/j.actbio.2010.09.004.

Haskett, D., Azhar, M., & Vande Geest, J.P. (2011). Biomechanical Considerations of Animal Models of Aortic Aneurysm. In Biomechanics and Mechanobiology of Aneurysms. 7, (pp. 401-421).Springer Nature. doi: 10.1007/8415_2011_76.

Keyes, J.T., Borowicz, S.M., Rader, J.H., Utzinger, U., Azhar, M., & Geest, J.P.V. (2011). Design and Demonstration of a Microbiaxial Optomechanical Device for Multiscale Characterization of Soft Biological Tissues with Two-Photon Microscopy. MICROSCOPY AND MICROANALYSIS, 17(2), 167-175.Oxford University Press (OUP). doi: 10.1017/S1431927610094341.

Keyes, J.T., Haskett, D.G., Utzinger, U., Azhar, M., & Geest, J.P.V. (2011). Adaptation of a Planar Microbiaxial Optomechanical Device for the Tubular Biaxial Microstructural and Macroscopic Characterization of Small Vascular Tissues. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 133(7), 075001.ASME International. doi: 10.1115/1.4004495.

Keyes, J.T., Yan, D., Rader, J.H., Utzinger, U., & Geest, J.P.V. (2011). A Gimbal-Mounted Pressurization Chamber for Macroscopic and Microscopic Assessment of Ocular Tissues. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 133(9), 095001.ASME International. doi: 10.1115/1.4004921.

Vande Geest, J.P., Simon, B.R., Rigby, P.H., & Newberg, T.P. (2011). Coupled Porohyperelastic Mass Transport (PHEXPT) Finite Element Models for Soft Tissues Using ABAQUS. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 133(4), 044502.ASME International. doi: 10.1115/1.4003489.

Vande Geest, J.P., Simon, B.R., Rigby, P.H., & Newberg, T.P. (2011). Coupled porohyperelastic mass transport (PHEXPT) finite element models for soft tissues using ABAQUS. Journal of biomechanical engineering, 133(4), 044502. doi: 10.1115/1.4003489.

Yan, D., McPheeters, S., Johnson, G., Utzinger, U., & Vande Geest, J.P. (2011). Microstructural Differences in the Human Posterior Sclera as a Function of Age and Race. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 52(2), 821-829.Association for Research in Vision and Ophthalmology (ARVO). doi: 10.1167/iovs.09-4651.

Alexander, M.J., Barkmeier-Kraemer, J.M., & Geest, J.P.V. (2010). Biomechanical Properties of Recurrent Laryngeal Nerve in the Piglet. ANNALS OF BIOMEDICAL ENGINEERING, 38(8), 2553-2562.Springer Nature. doi: 10.1007/s10439-010-0013-7.

Ayyalasomayajula, A., Polk, A., Basudhar, A., Missoum, S., Nissim, L., & Vande Geest, J.P. (2010). Three Dimensional Active Contours for the Reconstruction of Abdominal Aortic Aneurysms. ANNALS OF BIOMEDICAL ENGINEERING, 38(1), 164-176.Springer Nature. doi: 10.1007/s10439-009-9833-8.

Ayyalasomayajula, A., Vande Geest, J.P., & Simon, B.R. (2010). Porohyperelastic Finite Element Modeling of Abdominal Aortic Aneurysms. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 132(10), 104502.ASME International. doi: 10.1115/1.4002370.

Haskett, D., Johnson, G., Zhou, A., Utzinger, U., & Vande Geest, J. (2010). Microstructural and biomechanical alterations of the human aorta as a function of age and location. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 9(6), 725-736.Springer Nature. doi: 10.1007/s10237-010-0209-7.

Layman, R., Missoum, S., & Geest, J.V. (2010). Simulation and probabilistic failure prediction of grafts for aortic aneurysm. ENGINEERING COMPUTATIONS, 27(1-2), 84-105.Emerald. doi: 10.1108/02644401011008531.

Vad, S., Eskinazi, A., Corbett, T., McGloughlin, T., & Vande Geest, J.P. (2010). Determination of Coefficient of Friction for Self-Expanding Stent-Grafts. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 132(12), 121007.ASME International. doi: 10.1115/1.4002798.

Vad, S., Eskinazi, A., Corbett, T., McGloughlin, T., & Vande Geest, J.P. (2010). Determination of coefficient of friction for self-expanding stent-grafts. Journal of Biomechanical Engineering, 132(12). doi: 10.1115/1.4002798.

Warren, P.D., McGrath, D.V., & Geest, J.P.V. (2010). Effect of Crosslinker Length and Composition on the Hydrophobicity and Thermomechanical Response of Acrylate-Based Shape-Memory Polymers. MACROMOLECULAR MATERIALS AND ENGINEERING, 295(4), 386-396.Wiley. doi: 10.1002/mame.200900348.

Ashton, J.H., Geest, J.P.V., Simon, B.R., & Haskett, D.G. (2009). Compressive mechanical properties of the intraluminal thrombus in abdominal aortic aneurysms and fibrin-based thrombus mimics. JOURNAL OF BIOMECHANICS, 42(3), 197-201.Elsevier. doi: 10.1016/j.jbiomech.2008.10.024.

Junkin, M., Watson, J., Geest, J.P.V., & Wong, P.K. (2009). Template-Guided Self-Assembly of Colloidal Quantum Dots Using Plasma Lithography. ADVANCED MATERIALS, 21(12), 1247-+.Wiley. doi: 10.1002/adma.200802122.

Keyes, J., Junkin, M., Wong, P.K., & Geest, J.P.V. (2009). Computational simulation of a magnetic microactuator for tissue engineering applications. BIOMEDICAL MICRODEVICES, 11(6), 1259-1267.Springer Nature. doi: 10.1007/s10544-009-9345-1.

Mortazavi, A.M., Simon, B.R., Stamer, W.D., & Geest, J.P.V. (2009). Drained secant modulus for human and porcine peripapillary sclera using unconfined compression testing. EXPERIMENTAL EYE RESEARCH, 89(6), 892-897.Elsevier. doi: 10.1016/j.exer.2009.07.011.

Geest, J.P.V., Schmidt, D.E., Sacks, M.S., & Vorp, D.A. (2008). The effects of anisotropy on the stress analyses of patient-specific abdominal aortic aneurysms. ANNALS OF BIOMEDICAL ENGINEERING, 36(6), 921-932.Springer Nature. doi: 10.1007/s10439-008-9490-3.

Di Martino, E.S., Bohra, A., Vande Geest, J.P., Gupta, N., Makaroun, M.S., & Vorp, D.A. (2006). Biomechanical properties of ruptured versus electively repaired abdominal aortic aneurysm wall tissue. JOURNAL OF VASCULAR SURGERY, 43(3), 570-576.Elsevier. doi: 10.1016/j.jvs.2005.10.072.

Geest, J.P.V., Di Martino, E.S., Bohra, A., Makaroun, M.S., & Vorp, D.A. (2006). A biomechanics-based rupture potential index for abdominal aortic aneurysm risk assessment - Demonstrative application. ABDOMINAL AORTIC ANEURYSM: GENETICS, PATHOPHYSIOLOGY AND MOLECULAR BIOLOGY, 1085(1), 11-21.Wiley. doi: 10.1196/annals.1383.046.

Geest, J.P.V., Dillavou, E.D., Di Martino, E.S., Oberdier, M., Bohra, A., Makaroun, M.S., & Vorp, D.A. (2006). Gender-related differences in the tensile strength of abdominal aortic aneurysm. ABDOMINAL AORTIC ANEURYSM: GENETICS, PATHOPHYSIOLOGY AND MOLECULAR BIOLOGY, 1085(1), 400-402.Wiley. doi: 10.1196/annals.1383.048.

Geest, J.P.V., Sacks, M.S., & Vorp, D.A. (2006). The effects of aneurysm on the biaxial mechanical behavior of human abdominal aorta. JOURNAL OF BIOMECHANICS, 39(7), 1324-1334.Elsevier. doi: 10.1016/j.jbiomech.2005.03.003.

Vande Geest, J.P., Sacks, M.S., & Vorp, D.A. (2006). A planar biaxial constitutive relation for the luminal layer of intra-luminal thrombus in abdominal aortic aneurysms. JOURNAL OF BIOMECHANICS, 39(13), 2347-2354.Elsevier. doi: 10.1016/j.jbiomech.2006.05.011.

Vande Geest, J.P., Wang, D.H.J., Wisniewski, S.R., Makaroun, M.S., & Vorp, D.A. (2006). Towards a noninvasive method for determination of patient-specific wall strength distribution in abdominal aortic aneurysms. ANNALS OF BIOMEDICAL ENGINEERING, 34(7), 1098-1106.Springer Nature. doi: 10.1007/s10439-006-9132-6.

Freytes, D.O., Rundell, A.E., Vande Geest, J., Vorp, D.A., Webster, T.J., & Badylak, S.F. (2005). Analytically derived material properties of multilaminated extracellular matrix devices using the ball-burst test. BIOMATERIALS, 26(27), 5518-5531.Elsevier. doi: 10.1016/j.biomaterials.2005.01.070.

Vorp, D.A., & Geest, J.P.V. (2005). Biomechanical determinants of abdominal aortic aneurysm rupture. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 25(8), 1558-1566.Wolters Kluwer. doi: 10.1161/01.ATV.0000174129.77391.55.

Geest, J.P.V., Di Martino, E.S., & Vorp, D.A. (2004). An analysis of the complete strain field within FlexercellTM membranes. JOURNAL OF BIOMECHANICS, 37(12), 1923-1928.Elsevier. doi: 10.1016/j.jbiomech.2004.02.022.

Vande Geest, J.P., Sacks, M.S., & Vorp, D.A. (2004). Age dependency of the biaxial biornechanical Behavior of humian abdominal aorta. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 126(6), 815-822.ASME International. doi: 10.1115/1.1824121.

Kollech, H.G., & Vande Geest, J.P. (2021). Conforming versus nonconforming meshes in the finite element modeling of the human lamina cribrosa. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 62(8).

Liou, J.J., Tien, S., Yee, M., Kinchington, P.R., Girkin, C.A., & Vande Geest, J.P. (2019). Manipulating Gene Expression of Human Lamina Cribrosa Cells and Astrocytes. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 60(9).

Vande Geest, J.P., Kollech, H.G., Behkam, R., Jana, A., Utzinger, U., & Girkin, C.A. (2019). Biomechanical Response of the Lamina Cribrosa in Glaucomatous and Non glaucomatous samples. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 60(9).

Rice, P.F., Howard, C.C., Koevary, J.W., Danford, F.L., Gonzales, D.A., Vande Geest, J.P., Latt, L.D., Szivek, J.A., Amodei, R., Slayton, M., Barton, J.K., Amodei, R. (2018). Structural and functional assessment of intense therapeutic ultrasound effects on partial Achilles tendon transection. In Vo-Dinh, T., Mahadevan-Jansen, A., & Grundfest, W.S. (Eds.). In Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVI, 10484, (p. 104840o).SPIE, the international society for optics and photonics. doi: 10.1117/12.2288525.

Valencia-Rivero, K.T., Cruz, J.C., Briceño, J.C., D’Amore, A., Ye, S.H., Geest, J.V., & Wagner, W.R. (2018). Decreased Platelet Deposition in SIS-Based Vascular Grafts via Covalent Conjugation of RAFT Polymers. In 2018 IX International Seminar of Biomedical Engineering (SIB), 00, (pp. 1-6).Institute of Electrical and Electronics Engineers (IEEE). doi: 10.1109/sib.2018.8467727.

Geest, J.P.V., Ram, S., Howerton, S.J., Danford, F., Utzinger, U., & Rodriguez, J.J. (2016). Racioethnic Differences in the Biomechanical Environment of the Lamina Cribrosa. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 57(12).

O'Leary, S.A., Healey, D.A., Kavanagh, E.G., Walsh, M.T., McGloughlin, T.M., & Doyle, B.J. (2014). The Biaxial Biomechanical Behavior of Abdominal Aortic Aneurysm Tissue. In ANNALS OF BIOMEDICAL ENGINEERING, 42(12), (pp. 2440-2450).Springer Nature.United States. doi: 10.1007/s10439-014-1106-5.

Ayyalasomayajula, A., & Geest, J.V. (2013). Determining Heterogeneity in the Scleral Shell Using an Inverse Mechanics Approach. In Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, 1 B, (p. v01bt43a005).ASME International. doi: 10.1115/sbc2013-14747.

Keyes, J.T., Montilla, L.G., Witte, R.S., & Geest, J.P.V. (2013). Retention and Transport of Hydrophobic and Hydrophilic Drug Surrogate Molecules in Coronary Arteries Measured Nondestructively With Photoacoustic Ultrasound. In Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, 1 A, (p. v01at14a006).ASME International. doi: 10.1115/sbc2013-14626.

Pyne, J.D., Danford, F.L., & Geest, J.P.V. (2013). Phosphotungstic Acid Diffusion in Porcine Ocular Tissue for MicroCT Shape Reconstruction. In Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, 1 A, (p. v01at05a010).ASME International. doi: 10.1115/sbc2013-14534.

Shu, Q., Ardila, D.C., Sanfelice, R.G., & Vande Geest, J.P. (2013). A Hybrid Model of a Genetic Regulatory Network in Mammalian Sclera. In Electronic Proceedings in Theoretical Computer Science, 125, (pp. 99-105).Open Publishing Association. doi: 10.4204/eptcs.125.8.

Williams, M., Barkmeier-Kraemer, J., Utzinger, U., & Geest, J.V. (2013). Biomechanical and Microstructural Response of Recurrent Laryngeal Nerve in Pigs. In Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, 1 B, (p. v01bt54a003).ASME International. doi: 10.1115/sbc2013-14618.

Ayyalasomayajula, A., & Geest, J.P.V. (2012). 3D Reconstruction of Scleral Shell Using Three Dimensional Active Contours. In ASME 2012 Summer Bioengineering Conference, Parts A and B, (pp. 1181-1182).ASME International. doi: 10.1115/sbc2012-80618.

Haskett, D., Utzinger, U., Azhar, M., & Geest, J.V. (2012). Progressive Alterations in Biomechanical Response of a Mouse Model of Aneurysm. In ASME 2012 Summer Bioengineering Conference, Parts A and B, (pp. 1269-1270).ASME International. doi: 10.1115/sbc2012-80321.

Keyes, J.T., Lockwood, D.R., & Geest, J.P.V. (2012). Alterations in Finite Element Results Given Constitutive Models From Tubular and Planar Biaxial Testing of the Same Porcine Coronary Arteries. In ASME 2012 Summer Bioengineering Conference, Parts A and B, (pp. 979-980).ASME International. doi: 10.1115/sbc2012-80351.

Haskett, D., Johnson, G., Azhar, M., & Geest, J.V. (2011). Biomechanical and Microstructural Analysis of Wildtype (C57BL6) Mouse Aorta. In ASME 2011 Summer Bioengineering Conference, Parts A and B, (PARTS A AND B), (pp. 67-68).ASME International. doi: 10.1115/sbc2011-53729.

Keyes, J.T., Simon, B.R., & Geest, J.P.V. (2011). Transport in Pulsatile Axisymmetric Stented Arterial Models From Location-Dependent Variations in Permeability and Mechanical Properties. In ASME 2011 Summer Bioengineering Conference, Parts A and B, (PARTS A AND B), (pp. 813-814).ASME International. doi: 10.1115/sbc2011-53998.

Yan, D., Keyes, J.T., & Geest, J.P.V. (2011). Quantitative Measurements of Pressure Dependent Laminar Cribrosa Microstructure in Human Eyes. In ASME 2011 Summer Bioengineering Conference, Parts A and B, (PARTS A AND B), (pp. 435-436).ASME International. doi: 10.1115/sbc2011-53745.

Ashton, J.H., Mertz, J.A.M., Alexander, M.J., Slepian, M.J., Mills, J.L., & Geest, J.P.V. (2010). Functional Endoluminal Paving (FELP): Thermoforming, Biodegradation, and Mechanical Properties of a Novel Polymer Graft for Abdominal Aortic Aneurysms. In ASME 2010 Summer Bioengineering Conference, Parts A and B, (PARTS A AND B), (pp. 905-906).ASME International. doi: 10.1115/sbc2010-19463.

Haskett, D., Fouts, M., Utzinger, U., Larson, D., Azhar, M., & Geest, J.V. (2010). The Effects of Angiotensin II Infusion on the Mechanical Response and Microstructural Organization of Mouse Aorta. In ASME 2010 Summer Bioengineering Conference, Parts A and B, (PARTS A AND B), (pp. 725-726).ASME International. doi: 10.1115/sbc2010-19635.

Keyes, J.T., Borowicz, S., Rader, J., Utzinger, U., & Geest, J.P.V. (2010). Demonstration of a Multiscale Biaxial Tensile Testing Device: Simultaneous Mechanical and Microstructural Response of Porcine Coronary Artery. In ASME 2010 Summer Bioengineering Conference, Parts A and B, (PARTS A AND B), (pp. 529-530).ASME International. doi: 10.1115/sbc2010-19488.

Keyes, J.T., Borowicz, S., Utzinger, U., Azhar, M., & Geest, J.P.V. (2010). Quantification of the Biomechanical Differences in Wild-Type and Heterozygous TGF Beta2 Knockout Mice. In ASME 2010 Summer Bioengineering Conference, Parts A and B, (PARTS A AND B), (pp. 721-722).ASME International. doi: 10.1115/sbc2010-19482.

Keyes, J.T., Borowicz, S., Utzinger, U., Simon, B., & Geest, J.P.V. (2010). Determination of the Diffusivity and Location and Pressure Dependent Permeability of Porcine Coronary Arteries. In ASME 2010 Summer Bioengineering Conference, Parts A and B, (PARTS A AND B), (pp. 471-472).ASME International. doi: 10.1115/sbc2010-19490.

Ashton, J.H., Ayyalasomayajula, A., & Geest, J.P.V. (2009). Geometry of Abdominal Aortic Aneurysms and the Intraluminal Thrombus From 3D Image Reconstruction Using Active Contours. In ASME 2009 Summer Bioengineering Conference, Parts A and B, (PART A), (pp. 459-460).ASME International. doi: 10.1115/sbc2009-206645.

Ashton, J.H., Haskett, D.G., & Vande Geest, J.P. (2009). Comparison of the mechanical properties of the intraluminal thrombus in abdominal aortic aneurysms and thrombus mimics. In Proceedings of the ASME Summer Bioengineering Conference, SBC2008, (PART B), (pp. 579-580).

Ayyalasomayajula, A., Simon, B.R., & Vande Geest, J.P. (2009). Porohyperelastic simulation of abdominal aortic aneurysms. In Proceedings of the ASME Summer Bioengineering Conference, SBC2008, (PART B), (pp. 673-674).

Eskinazi, A.E., & Vande Geest, J.P. (2009). Quantifying the microstructure of human sclera using small angle light scattering. In Proceedings of the ASME Summer Bioengineering Conference, SBC2008, (PART B), (pp. 785-786).

Harper, J.L., Herlihy, R.N., & Geest, J.P.V. (2009). Characterizing the Compressive Resistance and Recovery of Shape Memory Polymer Cylinders. In ASME 2009 Summer Bioengineering Conference, Parts A and B, (PART A), (pp. 461-462).ASME International. doi: 10.1115/sbc2009-206672.

Haskett, D., Johnson, G., & Geest, J.V. (2009). Age related and location dependent microstructural and biomechanical characterization of human aortas. In Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, (PART B), (pp. 1323-1324).

Keyes, J., Junkin, M., Wong, P.K., & Vande Geest, J.P. (2009). Computational simulation of a mems-based microactuator for tissue engineering applications. In Proceedings of the ASME Summer Bioengineering Conference, SBC2008, (PART B), (pp. 571-572).

Vande Geest, J.P., & Simon, B.R. (2009). Analytical solutions to axisymmetric plane strain porous media-transport models in large arteries. In Proceedings of the ASME Summer Bioengineering Conference, SBC2008, (PART B), (pp. 647-648).

Warren, P.D., Bernal, R.R., Harper, J.L., Herlihy, R.N., & Geest, J.P.V. (2009). Thermomechanical and Hydrophobic Characterization of Shape Memory Polymers. In ASME 2009 Summer Bioengineering Conference, Parts A and B, (PART A), (pp. 69-70).ASME International. doi: 10.1115/sbc2009-206678.

Yan, D., & Geest, J.P.V. (2009). Microstructural Alterations in the Human Sclera: Do Age and Race Matter?. In ASME 2009 Summer Bioengineering Conference, Parts A and B, (PART A), (pp. 369-370).ASME International. doi: 10.1115/sbc2009-206668.

Junkin, M., Watson, J., Geest, J.P.V., & Wong, P.K. (2008). Adjustable nanomanufacturing using template-guided self-assembly. In 2008 3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, (pp. 1142-1146).Institute of Electrical and Electronics Engineers (IEEE). doi: 10.1109/nems.2008.4484519.

Ashton, J.H., & Geest, J.P.V. (2007). Development of a Thrombus Mimic in Abdominal Aortic Aneurysms. In ASME 2007 Summer Bioengineering Conference, (pp. 227-228).ASME International. doi: 10.1115/sbc2007-176625.

Layman, R., Missoum, S., & Geest, J.V. (2007). Towards the Prediction and Minimization of Device Failure for Endolvascular Grafts in Abdominal Aortic Aneurysms. In ASME 2007 Summer Bioengineering Conference, (pp. 395-396).ASME International. doi: 10.1115/sbc2007-176526.

Layman, R., Missoum, S., & Geest, J.V. (2007). Failure prediction and robust design of grafts for aortic aneurysms. In Collection of Technical Papers - AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics and Materials Conference, 3, (pp. 2257-2267).

Mortazavi, A., Geest, J.P.V., Simon, B.R., & Park, R.I. (2007). Analytic and Computational Comparison of Poroelastic and Elastic Biomechanical Models for Soft Ocular Tissues. In ASME 2007 Summer Bioengineering Conference, (pp. 359-360).ASME International. doi: 10.1115/sbc2007-176217.

Geest, J.P.V., Simon, B.R., & Mortazavi, A. (2006). Toward a model for local drug delivery in abdominal aortic aneurysms. In ABDOMINAL AORTIC ANEURYSM: GENETICS, PATHOPHYSIOLOGY AND MOLECULAR BIOLOGY, 1085(1), (pp. 396-399).Wiley.United States. doi: 10.1196/annals.1383.047.

Freytes, D.O., Geest, J.V., Thapa, A., Vorp, D.A., & Badylak, S.F. (2005). Mechanical characterization of native and esophageal graft in a dog model. In Proceedings of the 2005 Summer Bioengineering Conference, 2005, (pp. 1556-1557).

Geest, J.V., Bohra, A., Sun, W., Martino, E.D., Sacks, M., & Vorp, D. (2004). Development and 3D finite elment implementation of a multiaxial constitutive relation for abdominal aortic aneurysms. In Advances in Bioengineering, BED, (pp. 221-222).

Geest, J.P.V., Sacks, M.S., & Vorp, D.A. (2002). Age-Related Differences in the Biaxial Biomechanical Behavior of Human Abdominal Aorta. In Advances in Bioengineering, (pp. 115-116).ASME International. doi: 10.1115/imece2002-32509.

Research interests

biomechanics
constitutive modeling
extracellular matrix
finite element modeling
Ocular, vascular, and nerve...
polymer mechanics
tissue engineering