Fatima Syed

Development of biomimetic tissue engineered constructs for use in regenerative therapies or as model systems to study tissue development or disease states; understanding and manipulating tissue patterning in engineered tissues; stem cell biology; emphasis on craniofacial tissues�

  • (2015) NIH Pathway to Independence Award (NIH K99/R00).
  • (2009 - 2013) NIH National Research Service Award (NIH F31).

  • BSE, Materials Science and Engineering, University of Michigan
  • MSE, Materials Science and Engineering, University of Michigan
  • PhD, Bioengineering, University of Pittsburgh

  • Drewry, M.D., Dailey, M.T., Rothermund, K., Backman, C., Dahl, K.N., & Syed-Picard, F.N. (2022). Promoting and Orienting Axon Extension Using Scaffold-Free Dental Pulp Stem Cell Sheets. ACS Biomater Sci Eng, 8(2), 814-825.American Chemical Society (ACS). doi: 10.1021/acsbiomaterials.1c01517.
  • Rothermund, K., Calabrese, T.C., & Syed-Picard, F.N. (2022). Differential Effects of Escherichia coli- Versus Porphyromonas gingivalis-derived Lipopolysaccharides on Dental Pulp Stem Cell Differentiation in Scaffold-free Engineered Tissues. J Endod, 48(11), 1378-1386.e2.Elsevier. doi: 10.1016/j.joen.2022.08.010.
  • Ahmed, M.N., Shi, D., Dailey, M.T., Rothermund, K., Drewry, M.D., Calabrese, T.C., Cui, X.T., & Syed-Picard, F.N. (2021). Dental Pulp Cell Sheets Enhance Facial Nerve Regeneration via Local Neurotrophic Factor Delivery. Tissue Eng Part A, 27(17-18), 1128-1139.SAGE Publications. doi: 10.1089/ten.TEA.2020.0265.
  • Sonmez, U.M., Wood, A., Justus, K., Jiang, W., Syed-Picard, F., LeDuc, P.R., Kalinski, P., & Davidson, L.A. (2020). Chemotactic Responses of Jurkat Cells in Microfluidic Flow-Free Gradient Chambers. Micromachines (Basel), 11(4).MDPI. doi: 10.3390/mi11040384.
  • Basu, A., Rothermund, K., Ahmed, M.N., & Syed-Picard, F.N. (2019). Self-Assembly of an Organized Cementum-Periodontal Ligament-Like Complex Using Scaffold-Free Tissue Engineering. Front Physiol, 10(APR), 422.Frontiers. doi: 10.3389/fphys.2019.00422.
  • Syed-Picard, F.N., Du, Y., Hertsenberg, A.J., Palchesko, R., Funderburgh, M.L., Feinberg, A.W., & Funderburgh, J.L. (2018). Scaffold-free tissue engineering of functional corneal stromal tissue. J Tissue Eng Regen Med, 12(1), 59-69.Hindawi. doi: 10.1002/term.2363.
  • Syed-Picard, F.N., Du, Y., Lathrop, K.L., Mann, M.M., Funderburgh, M.L., & Funderburgh, J.L. (2015). Dental pulp stem cells: a new cellular resource for corneal stromal regeneration. Stem Cells Transl Med, 4(3), 276-285.Oxford University Press (OUP). doi: 10.5966/sctm.2014-0115.
  • Basu, S., Hertsenberg, A.J., Funderburgh, M.L., Burrow, M.K., Mann, M.M., Du, Y., Lathrop, K.L., Syed-Picard, F.N., Adams, S.M., Birk, D.E., & Funderburgh, J.L. (2014). Human limbal biopsy-derived stromal stem cells prevent corneal scarring. Sci Transl Med, 6(266), 266ra172.American Association for the Advancement of Science (AAAS). doi: 10.1126/scitranslmed.3009644.
  • Syed-Picard, F.N., Ray, H.L., Kumta, P.N., & Sfeir, C. (2014). Scaffoldless tissue-engineered dental pulp cell constructs for endodontic therapy. J Dent Res, 93(3), 250-255.SAGE Publications. doi: 10.1177/0022034513517901.
  • Syed-Picard, F.N., Shah, G.A., Costello, B.J., & Sfeir, C. (2014). Regeneration of periosteum by human bone marrow stromal cell sheets. J Oral Maxillofac Surg, 72(6), 1078-1083.Elsevier. doi: 10.1016/j.joms.2014.02.005.
  • Syed-Picard, F.N., Jayaraman, T., Lam, R.S.K., Beniash, E., & Sfeir, C. (2013). Osteoinductivity of calcium phosphate mediated by connexin 43. Biomaterials, 34(15), 3763-3774.Elsevier. doi: 10.1016/j.biomaterials.2013.01.095.
  • Embree, M.C., Kilts, T.M., Ono, M., Inkson, C.A., Syed-Picard, F., Karsdal, M.A., Oldberg, A., Bi, Y., & Young, M.F. (2010). Biglycan and fibromodulin have essential roles in regulating chondrogenesis and extracellular matrix turnover in temporomandibular joint osteoarthritis. Am J Pathol, 176(2), 812-826.Elsevier. doi: 10.2353/ajpath.2010.090450.
  • Smietana, M.J., Syed-Picard, F.N., Ma, J., Kostrominova, T., Arruda, E.M., & Larkin, L.M. (2010). The effect of implantation on scaffoldless three-dimensional engineered bone constructs (vol 45, pg 512, 2009). IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 46(1), 82.Springer Nature. doi: 10.1007/s11626-009-9251-0.
  • Kilts, T., Ameye, L., Syed-Picard, F., Ono, M., Berendsen, A.D., Oldberg, A., Heegaard, A.M., Bi, Y., & Young, M.F. (2009). Potential roles for the small leucine-rich proteoglycans biglycan and fibromodulin in ectopic ossification of tendon induced by exercise and in modulating rotarod performance. Scand J Med Sci Sports, 19(4), 536-546.Wiley. doi: 10.1111/j.1600-0838.2009.00909.x.
  • Smietana, M.J., Syed-Picard, F.N., Ma, J., Kostrominova, T., Arruda, E.M., & Larkin, L.M. (2009). The effect of implantation on scaffoldless three-dimensional engineered bone constructs. In Vitro Cell Dev Biol Anim, 45(9), 512-522.Springer Nature. doi: 10.1007/s11626-009-9216-3.
  • Syed-Picard, F.N., Larkin, L.M., Shaw, C.M., & Arruda, E.M. (2009). Three-dimensional engineered bone from bone marrow stromal cells and their autogenous extracellular matrix. Tissue Eng Part A, 15(1), 187-195.SAGE Publications. doi: 10.1089/ten.tea.2007.0140.

  • Syed-Picard, F.N., Du, Y., Palchesko, R., Funderburgh, M.L., Hertsenberg, A., Feinberg, A.W., & Funderburgh, J.L. (2015). Scaffold-free engineering of stromal lamellar tissue. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 56(7).
  • Syed-Picard, F.N., Mann, M., Funderburgh, M.L., Lathrop, K.L., & Funderburgh, J.L. (2014). Dental Pulp Stem Cells for Corneal Stroma Regeneration. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 55(13).
  • Syed-Picard, F.N., Larkin, L.M., & Arruda, E.M. (2007). Development of scaffold-less 3D bone tissue engineered from rat bone marrow stromal. In FASEB JOURNAL, 21(6), (p. A1233).
Research Interests
Biomedical engineering Dentistry Ophthalmology and optometry Medical physiology Medical biotechnology Biochemistry and cell biology
headshot of Fatima Syed
Contact Fatima Syed
Associate Professor
syedpicard@pitt.edu
Work: (412) 383-7225
Linkedin
@scaffoldfree