headshot of Emrullah Korkmaz

Emrullah Korkmaz

Assistant Professor
EK001@pitt.edu

overview

We work at the interface of bioengineering, skin science, and immunology to 'engineer' systemic immune responses based on cutaneous immunomodulation using patient-friendly microtechnologies, with the goal of developing safer and more effective immunotherapies for cancer, allergy, and infectious disease.

about

PhD, Carnegie Mellon University

Balmert, S.C., Ghozloujeh, Z.G., Carey, C.D., Williams, L.H., Zhang, J., Shahi, P., Amer, M., Sumpter, T.L., Erdos, G., Korkmaz, E., & Falo, L.D. (2022). A microarray patch SARS-CoV-2 vaccine induces sustained antibody responses and polyfunctional cellular immunity. iScience, 25(10), 105045.Elsevier. doi: 10.1016/j.isci.2022.105045.

Bandyopadhyay, M., Morelli, A.E., Balmert, S.C., Ward, N.L., Erdos, G., Sumpter, T.L., Korkmaz, E., Kaplan, D.H., Oberbarnscheidt, M.H., Tkacheva, O., Shufesky, W.J., Falo, L.D., & Larregina, A.T. (2022). Skin codelivery of contact sensitizers and neurokinin-1 receptor antagonists integrated in microneedle arrays suppresses allergic contact dermatitis. J Allergy Clin Immunol, 150(1), 114-130.Elsevier. doi: 10.1016/j.jaci.2021.12.794.

Yonet-Tanyeri, N., Amer, M., Balmert, S.C., Korkmaz, E., Falo, L.D., & Little, S.R. (2022). Microfluidic Systems For Manufacturing of Microparticle-Based Drug-Delivery Systems: Design, Construction, and Operation. ACS Biomater Sci Eng, 8(7), 2864-2877.American Chemical Society (ACS). doi: 10.1021/acsbiomaterials.2c00066.

Balmert, S.C., Ghozloujeh, Z.G., Carey, C.D., Akilov, O.E., Korkmaz, E., & Falo, L.D. (2021). Research Techniques Made Simple: Skin-Targeted Drug and Vaccine Delivery Using Dissolvable Microneedle Arrays. J Invest Dermatol, 141(11), 2549-2557.e1.Elsevier. doi: 10.1016/j.jid.2021.07.177.

Kim, E., Weisel, F.J., Balmert, S.C., Khan, M.S., Huang, S., Erdos, G., Kenniston, T.W., Carey, C.D., Joachim, S.M., Conter, L.J., Weisel, N.M., Okba, N.M.A., Haagmans, B.L., Percivalle, E., Cassaniti, I., Baldanti, F., Korkmaz, E., Shlomchik, M.J., Falo, L.D., & Gambotto, A. (2021). A single subcutaneous or intranasal immunization with adenovirus-based SARS-CoV-2 vaccine induces robust humoral and cellular immune responses in mice. Eur J Immunol, 51(7), 1774-1784.Wiley. doi: 10.1002/eji.202149167.

Korkmaz, E., Balmert, S.C., Carey, C.D., Erdos, G., & Falo, L.D. (2021). Emerging skin-targeted drug delivery strategies to engineer immunity: A focus on infectious diseases. Expert Opin Drug Deliv, 18(2), 151-167.Taylor & Francis. doi: 10.1080/17425247.2021.1823964.

Korkmaz, E., Balmert, S.C., Sumpter, T.L., Carey, C.D., Erdos, G., & Falo, L.D. (2021). Microarray patches enable the development of skin-targeted vaccines against COVID-19. Adv Drug Deliv Rev, 171, 164-186.Elsevier. doi: 10.1016/j.addr.2021.01.022.

Balmert, S.C., Carey, C.D., Falo, G.D., Sethi, S.K., Erdos, G., Korkmaz, E., & Falo, L.D. (2020). Dissolving undercut microneedle arrays for multicomponent cutaneous vaccination. J Control Release, 317, 336-346.Elsevier. doi: 10.1016/j.jconrel.2019.11.023.

Erdos, G., Balmert, S.C., Carey, C.D., Falo, G.D., Patel, N.A., Zhang, J., Gambotto, A., Korkmaz, E., & Falo, L.D. (2020). Improved Cutaneous Genetic Immunization by Microneedle Array Delivery of an Adjuvanted Adenovirus Vaccine. J Invest Dermatol, 140(12), 2528-2531.e2.Elsevier. doi: 10.1016/j.jid.2020.03.966.

Kim, E., Erdos, G., Huang, S., Kenniston, T.W., Balmert, S.C., Carey, C.D., Raj, V.S., Epperly, M.W., Klimstra, W.B., Haagmans, B.L., Korkmaz, E., Falo, L.D., & Gambotto, A. (2020). Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development. EBioMedicine, 55, 102743.Elsevier. doi: 10.1016/j.ebiom.2020.102743.

Korkmaz, E., & Falo, L.D. (2020). Spherical Nucleic Acids as Emerging Topical Therapeutics: A Focus on Psoriasis. J Invest Dermatol, 140(2), 278-281.Elsevier. doi: 10.1016/j.jid.2019.07.683.

Balmert, S.C., Ghozloujeh, Z.G., Carey, C., Sumpter, T.L., Erdos, G., Korkmaz, E., & Falo, L.J. (2022). Microarray patch-based adenovirus vaccines enable effective skin immunization. In JOURNAL OF INVESTIGATIVE DERMATOLOGY, 142(8), (p. S102).

Balmert, S.C., Ghozloujeh, Z.G., Carey, C.D., Sumpter, T.L., Erdos, G., Korkmaz, E., & Falo, L.D. (2021). A multicomponent skin-targeted COVID-19 vaccine elicits robust humoral and cellular immune responses. In JOURNAL OF INVESTIGATIVE DERMATOLOGY, 141(5), (p. S6).

Balmert, S.C., Carey, C.D., Erdos, G., Korkmaz, E., Little, S.R., & Falo, L.D. (2020). Engineering the skin with microneedle arrays to induce immune tolerance. In JOURNAL OF INVESTIGATIVE DERMATOLOGY, 140(7), (p. S11).

Mizes, A., Carey, C.D., Friedman, B., Zhang, J., Korkmaz, E., Balmert, S., Erdos, G., & Falo, L.D. (2020). Topical chemo-immunotherapy of melanoma. In JOURNAL OF INVESTIGATIVE DERMATOLOGY, 140(7), (p. S9).

Korkmaz, E., Sumpter, T., Li, Y., & Falo, L.D. (2019). Skin-targeted delivery of crude peanut extracts using dissolving microneedle arrays. In JOURNAL OF INVESTIGATIVE DERMATOLOGY, 139(5), (p. S11).

Erdos, G., Falo, G., Korkmaz, E., Ozdoganlar, B., & Falo, L.D.J. (2018). Microneedle array delivery of skin targeted adenovector vaccines. In JOURNAL OF INVESTIGATIVE DERMATOLOGY, 138(5), (p. S20).Elsevier. doi: 10.1016/j.jid.2018.03.124.