(2010) Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows (F31).
(1995) Young Investigator Award American Association of Dental Research, Chicago Chapter.
(1994) Fifth Annual Dental Research Symposium, First Place Award Northwestern University Chicago.
(1992) Young Investigator’s Competition, First Place Award Fifth International Conference on the Chemistry And Biology of the Mineralized Tissues.
(1990 - 1996) Dentist Scientist Award for Ph.D. Training National Institute of Dental and Craniofacial Research.
Ph.D., Molecular Biology and Biochemistry Thesis: Phosphorylation of dentin extracellular matrix proteins by protein kinases, Northwestern University, 1990 - 1996
D.D.S., Thesis: Pathological Relationship and Treatment of the Opening Between the Oral and Sinus Cavities, Universite Louis Pasteur of Dental Surgery, 1985 - 1990
Kobyra, J.A., Shehabeldin, M., Little, S.R., & Sfeir, C. (2026). Treating periodontal disease: from antimicrobials to immunomodulation. Trends Pharmacol Sci, 47(1), 40-52.Elsevier. doi: 10.1016/j.tips.2025.11.005.
Pacheco, C.M.F., Maltos, K.L.M., Shehabeldin, M.S., Thomas, L.L., Zhuang, Z., Yoshizawa, S., Verdelis, K., Gaffen, S.L., Garlet, G.P., Little, S.R., & Sfeir, C. (2021). Local Sustained Delivery of Anti-IL-17A Antibodies Limits Inflammatory Bone Loss in Murine Experimental Periodontitis. J Immunol, 206(10), 2386-2392.Oxford University Press (OUP). doi: 10.4049/jimmunol.2001432.
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Zaky, S.H., AlQahtani, Q., Chen, J., Patil, A., Taboas, J., Beniash, E., Ray, H., & Sfeir, C. (2020). Effect of the Periapical "Inflammatory Plug" on Dental Pulp Regeneration: A Histologic In Vivo Study. J Endod, 46(1), 51-56.Elsevier. doi: 10.1016/j.joen.2019.10.006.
Hong, D., Zaky, S.H., Chong, R., Lukashova, L., Beniash, E., Verdelis, K., Witte, F., & Sfeir, C. (2019). Controlling magnesium corrosion and degradation-regulating mineralization using matrix GLA protein. Acta Biomater, 98, 142-151.Elsevier. doi: 10.1016/j.actbio.2019.05.048.
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Zhao, D., Brown, A., Wang, T., Yoshizawa, S., Sfeir, C., & Heineman, W.R. (2018). In vivo quantification of hydrogen gas concentration in bone marrow surrounding magnesium fracture fixation hardware using an electrochemical hydrogen gas sensor. Acta Biomater, 73, 559-566.Elsevier. doi: 10.1016/j.actbio.2018.04.032.
Zaky, S.H., Lee, K.W., Gao, J., Jensen, A., Verdelis, K., Wang, Y., Almarza, A.J., & Sfeir, C. (2017). Poly (glycerol sebacate) elastomer supports bone regeneration by its mechanical properties being closer to osteoid tissue rather than to mature bone. Acta Biomater, 54, 95-106.Elsevier. doi: 10.1016/j.actbio.2017.01.053.
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Chaya, A., Yoshizawa, S., Verdelis, K., Myers, N., Costello, B.J., Chou, D.T., Pal, S., Maiti, S., Kumta, P.N., & Sfeir, C. (2015). In vivo study of magnesium plate and screw degradation and bone fracture healing. Acta Biomater, 18, 262-269.Elsevier. doi: 10.1016/j.actbio.2015.02.010.
Chaya, A., Yoshizawa, S., Verdelis, K., Noorani, S., Costello, B.J., & Sfeir, C. (2015). Fracture healing using degradable magnesium fixation plates and screws. J Oral Maxillofac Surg, 73(2), 295-305.Elsevier. doi: 10.1016/j.joms.2014.09.007.
Yoshizawa, S., Chaya, A., Verdelis, K., Bilodeau, E.A., & Sfeir, C. (2015). An in vivo model to assess magnesium alloys and their biological effect on human bone marrow stromal cells. Acta Biomater, 28, 234-239.Elsevier. doi: 10.1016/j.actbio.2015.08.037.
Sfeir, C., Fang, P.A., Jayaraman, T., Raman, A., Xiaoyuan, Z., & Beniash, E. (2014). Synthesis of bone-like nanocomposites using multiphosphorylated peptides. Acta Biomater, 10(5), 2241-2249.Elsevier. doi: 10.1016/j.actbio.2014.01.007.
Syed-Picard, F.N., Shah, G.A., Costello, B.J., & Sfeir, C. (2014). Regeneration of periosteum by human bone marrow stromal cell sheets. J Oral Maxillofac Surg, 72(6), 1078-1083.Elsevier. doi: 10.1016/j.joms.2014.02.005.
Yoshizawa, S., Brown, A., Barchowsky, A., & Sfeir, C. (2014). Magnesium ion stimulation of bone marrow stromal cells enhances osteogenic activity, simulating the effect of magnesium alloy degradation. Acta Biomater, 10(6), 2834-2842.Elsevier. doi: 10.1016/j.actbio.2014.02.002.
Sfeir, C., Lee, D., Li, J., Zhang, X., Boskey, A.L., & Kumta, P.N. (2011). Expression of phosphophoryn is sufficient for the induction of matrix mineralization by mammalian cells. J Biol Chem, 286(23), 20228-20238.Elsevier. doi: 10.1074/jbc.M110.209528.
(2010). Regenerative medicine for craniomaxillofacial surgery. Oral Maxillofac Surg Clin North Am, 22, 33-42.
Ko, H.F., Sfeir, C., & Kumta, P.N. (2010). Novel synthesis strategies for natural polymer and composite biomaterials as potential scaffolds for tissue engineering. Philos Trans A Math Phys Eng Sci, 368(1917), 1981-1997.The Royal Society. doi: 10.1098/rsta.2010.0009.
(2009). Cell Derived Hierarchical Assembly of a Novel Phosphophoryn-Based Biomaterial. Cells Tissues Organs. 2008(Epub).
(2009). Biodegradable Mg corrosion and osteoblast cell culture studies. Materials Science and Engineering C,. 29, 1814-1821.
(2007). Influence of the Synthesis Parameters on the Transfection Efficiency of Nanostructured Calcium Phosphates (NanoCaPs) for Non-Viral Gene Delivery. Biomaterials, 28, 1267-1279.
Ko, H.F., Sfeir, C., & Kumta, P.N. (2007). In situ synthesis and characterization of porous polymer-ceramic composites as scaffolds for gene delivery. MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS, 27(3), 479-483.Elsevier. doi: 10.1016/j.msec.2006.05.045.
(2006). ECM-mediated signaling by dentin phosphophoryn involves activation of the Smad pathway independent of BMP. J Biol Chem., 281, 5341-7.
(2005). Novel Synthesis and Characterization of Nanostructured Calcium Phosphates for Biomedical Applications. Acta Biomaterialia, 1, 56-83.
Sfeir, C., Ho, L., Doll, B.A., Azari, K., & Hollinger, J.O. (2005). Fracture Repair. In Bone Regeneration and Repair. (pp. 21-44).Springer Nature. doi: 10.1385/1-59259-863-3:021.
Jadlowiec, J., Koch, H., Zhang, X., Campbell, P.G., Seyedain, M., & Sfeir, C. (2004). Phosphophoryn regulates the gene expression and differentiation of NIH3T3, MC3T3-E1, and human mesenchymal stem cells via the integrin/MAPK signaling pathway. J Biol Chem, 279(51), 53323-53330.Elsevier. doi: 10.1074/jbc.M404934200.
Narayan, R.J., Kumta, P.N., Sfeir, C., Lee, D.H., Olton, D., & Choi, D.W. (2004). Nanostructured ceramics in medical devices: Applications and prospects. JOM, 56(10), 38-43.Springer Nature. doi: 10.1007/s11837-004-0289-x.
Pola, E., Gao, W., Zhou, Y., Pola, R., Lattanzi, W., Sfeir, C., Gambotto, A., & Robbins, P.D. (2004). Efficient bone formation by gene transfer of human LIM mineralization protein-3. Gene Ther, 11(8), 683-693.Springer Nature. doi: 10.1038/sj.gt.3302207.
(2002). A Review of Therapeutic Potential of Bone Morphogenetic Proteins. Expert Opin. Investig. Drugs, 10, 1677-1686.
Thomas, C.H., Collier, J.H., Sfeir, C.S., & Healy, K.E. (2002). Engineering gene expression and protein synthesis by modulation of nuclear shape. Proc Natl Acad Sci U S A, 99(4), 1972-1977.Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.032668799.
(2001). Critical Aspects of Tissue Engineered Therapy for Bone Regeneration. Critical Reviews in Eukaryotic Gene Expression, 11(-3)), 173-98.
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Gargiulo, A.V., Chen, P.W., & Sfeir, C. (1996). Use of a bioresorbable pin and membrane barrier for guided-tissue regeneration. 89, 26-28.Chicago Dental Society Review.
Sfeir, C., & Veis, A. (1995). Casein kinase localization in the endoplasmic reticulum of the ROS 17/2.8 cell line. J Bone Miner Res, 10(4), 607-615.Oxford University Press (OUP). doi: 10.1002/jbmr.5650100414.
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