headshot

Cecelia Yates-Binder

Associate Professor
Assistant Professor
Bioengineering Department

about

(2013) Immunohistochemistry and Microscopy Course (IHCM) travel award.

(2013) AAI 2013 annual meeting Presentation Award, Honolulu, HI.

(2011) ASIP 2011 Excellence in Science Award, Washington, DC.

(2010) University of Pittsburgh, Department of Pathology, Postdoctoral Award, Pittsburgh, PA.

(2009) ASIP Educational Fund Scholar, New Orleans, LA.

(2008) ASIP's 2008 Experimental Pathologist-in-Graduate Training Award, San Diego, CA.

(2008) FASEB-MARC Minority Trainee Travel Award, San Diego, CA.

(2007) European Tissue Repair Young Investigator Award, South Hampton, UK.

(2006) University of Pittsburgh, Department of Pathology, 1st prize (graduate presentation).

(2006) Wound Healing Society Young Investigator Award Finalist, Scottsdale, AZ.

BS, Major: Biology / Minor: Chemistry, Tuskegee University, 1998 - 2001

PhD, Integrative Sciences, Cellular and Molecular Pathology, Tuskegee University / University of Pittsburgh, 2004 - 2009

Swogger, J., Conner, I.P., Happ-Smith, C., Kemmerer, M.C., Julian, D.R., Wells, A., Schuman, J.S., Yates, C.C., & Davis, R. (2021). Novel combination therapy reduces subconjunctival fibrosis after glaucoma filtration surgery in the rabbit model. CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 49(1), 60-69.Wiley. doi: 10.1111/ceo.13884.

Cheikhi, A.M., Johnson, Z.I., Julian, D.R., Wheeler, S., Feghali-Bostwick, C., Conley, Y.P., Lyons-Weiler, J., & Yates, C.C. (2020). Prediction of severity and subtype of fibrosing disease using model informed by inflammation and extracellular matrix gene index. PLOS ONE, 15(10), e0240986.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0240986.

Johnson, Z.I., Jones, J.D., Mukherjee, A., Rena, D., Feghali-Bostwick, C., Conley, Y.P., & Yates, C.C. (2018). Novel classification for global gene signature model for predicting severity of systemic sclerosis. PLOS ONE, 13(6), e0199314.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0199314.

Yates, C.C., Nuschke, A., Rodrigues, M., Whaley, D., Dechant, J.J., Taylor, D.P., & Wells, A. (2017). Improved Transplanted Stem Cell Survival in a Polymer Gel Supplemented With Tenascin C Accelerates Healing and Reduces Scarring of Murine Skin Wounds. CELL TRANSPLANTATION, 26(1), 103-113.SAGE Publications. doi: 10.3727/096368916X692249.

Yates, C.C., Rodrigues, M., Nuschke, A., Johnson, Z.I., Whaley, D., Stolz, D., Newsome, J., & Wells, A. (2017). Multipotent stromal cells/mesenchymal stem cells and fibroblasts combine to minimize skin hypertrophic scarring. STEM CELL RESEARCH & THERAPY, 8(1), 193.Springer Science and Business Media LLC. doi: 10.1186/s13287-017-0644-9.

Bodnar, R.J., Satish, L., Yates, C.C., & Wells, A. (2016). Pericytes: A newly recognized player in wound healing. WOUND REPAIR AND REGENERATION, 24(2), 204-214.Wiley. doi: 10.1111/wrr.12415.

Quintana, M.T., Parry, T.L., He, J., Yates, C.C., Sidorova, T.N., Murray, K.T., Bain, J.R., Newgard, C.B., Muehlbauer, M., Eaton, S.C., Hishiya, A., Takayama, S., & Willis, M.S. (2016). Cardiomyocyte-Specific Human Bcl2-Associated Anthanogene 3 P209L Expression Induces Mitochondrial Fragmentation, Bcl2-Associated Anthanogene 3 Haploinsufficiency, and Activates p38 Signaling. AMERICAN JOURNAL OF PATHOLOGY, 186(8), 1989-2007.Elsevier BV. doi: 10.1016/j.ajpath.2016.03.017.

Wells, A., Nuschke, A., & Yates, C.C. (2016). Skin tissue repair: Matrix microenvironmental influences. MATRIX BIOLOGY, 49, 25-36.Elsevier BV. doi: 10.1016/j.matbio.2015.08.001.

He, J., Quintana, M.T., Sullivan, J., Parry, T.L., Grevengoed, T.J., Schisler, J.C., Hill, J.A., Yates, C.C., Mapanga, R.F., Essop, M.F., Stansfield, W.E., Bain, J.R., Newgard, C.B., Muehlbauer, M.J., Han, Y., Clarke, B.A., & Willis, M.S. (2015). MuRF2 regulates PPAR gamma 1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet. CARDIOVASCULAR DIABETOLOGY, 14(1), 97.Springer Science and Business Media LLC. doi: 10.1186/s12933-015-0252-x.

Quintana, M.T., He, J., Sullivan, J., Grevengoed, T., Schisler, J., Han, Y., Hill, J.A., Yates, C.C., Stansfield, W.E., Mapanga, R.F., Essop, M.F., Muehlbauer, M.J., Newgard, C.B., Bain, J.R., & Willis, M.S. (2015). Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet. BMC ENDOCRINE DISORDERS, 15(1), 36.Springer Science and Business Media LLC. doi: 10.1186/s12902-015-0028-z.

Xu, L., Yates, C.C., Lockyer, P., Xie, L., Bevilacqua, A., He, J., Lander, C., Patterson, C., & Willis, M. (2014). MMI-0100 inhibits cardiac fibrosis in myocardial infarction by direct actions on cardiomyocytes and fibroblasts via MK2 inhibition. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 77, 86-101.Elsevier BV. doi: 10.1016/j.yjmcc.2014.09.011.

Yates, C.C., Mitchell, A.J., Booth, M.Y., Williams, D.K., Lowe, L.M., & Hall, R.W. (2014). The Effects of Massage Therapy to Induce Sleep in Infants Born Preterm. PEDIATRIC PHYSICAL THERAPY, 26(4), 405-410.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/PEP.0000000000000081.

Mitchell, A.J., Yates, C.C., Williams, D.K., Chang, J.Y., & Hall, R.W. (2013). Does daily kangaroo care provide sustained pain and stress relief in preterm infants?. J Neonatal Perinatal Med, 6(1), 45-52.IOS Press. doi: 10.3233/NPM-1364212.

Rodrigues, M., Yates, C.C., Nuschke, A., Griffith, L., & Wells, A. (2013). The Matrikine Tenascin-C Protects Multipotential Stromal Cells/Mesenchymal Stem Cells from Death Cytokines Such as FasL. TISSUE ENGINEERING PART A, 19(17-18), 1972-1983.Mary Ann Liebert Inc. doi: 10.1089/ten.tea.2012.0568.

Yates, C.C., Mitchell, A.J., Lowe, L.M., Lee, A., & Hall, R.W. (2013). Safety of Noninvasive Electrical Stimulation of Acupuncture Points During a Routine Neonatal Heel Stick. Med Acupunct, 25(4), 285-290.Mary Ann Liebert Inc. doi: 10.1089/acu.2012.0952.

Yates, C.C., Hebda, P., & Wells, A. (2012). Skin Wound Healing and Scarring: Fetal Wounds and Regenerative Restitution. BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS, 96(4), 325-333.Wiley. doi: 10.1002/bdrc.21024.

Yates, C.C., Whaley, D., & Wells, A. (2012). Transplanted Fibroblasts Prevents Dysfunctional Repair in a Murine CXCR3-Deficient Scarring Model. CELL TRANSPLANTATION, 21(5), 919-931.SAGE Publications. doi: 10.3727/096368911X623817.

Yates-Binder, C.C., Rodgers, M., Jaynes, J., Wells, A., Bodnar, R.J., & Turner, T. (2012). An IP-10 (CXCL10)-Derived Peptide Inhibits Angiogenesis. In Proost, P. (Ed.). PLOS ONE, 7(7), e40812.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0040812.

Garrison, M.K., Yates, C.C., Reese, N.B., Skinner, R.D., & Garcia-Rill, E. (2011). Wind-up of stretch reflexes as a measure of spasticity in chronic spinalized rats: The effects of passive exercise and modafinil. EXPERIMENTAL NEUROLOGY, 227(1), 104-109.Elsevier BV. doi: 10.1016/j.expneurol.2010.09.019.

Yates, C.C., Bodnar, R., & Wells, A. (2011). Matrix control of scarring. CELLULAR AND MOLECULAR LIFE SCIENCES, 68(11), 1871-1881.Springer Science and Business Media LLC. doi: 10.1007/s00018-011-0663-0.

Yates, C.C., Whaley, D.L., & Wells, A. (2011). DEFICIENT DERMAL REMODELING CORRECTED BY ADULT AND FETAL FIBROBLASTS TRANSPLANTATION. WOUND REPAIR AND REGENERATION, 19(2), A61.

Yates, C.C., Jaynes, J., Wells, A., Bodnar, R., & Turner, T. (2010). Targeting Angiogenesis: A therapeutic approach using a synthetic derived peptide. FASEB JOURNAL, 24.

Yates, C.C., Krishna, P., Whaley, D., Bodnar, R., Turner, T., & Wells, A. (2010). Lack of CXC Chemokine Receptor 3 Signaling Leads to Hypertrophic and Hypercellular Scarring. AMERICAN JOURNAL OF PATHOLOGY, 176(4), 1743-1755.Elsevier BV. doi: 10.2353/ajpath.2010.090564.

Bodnar, R.J., Yates, C.C., Rodgers, M.E., Du, X., & Wells, A. (2009). IP-10 induces dissociation of newly formed blood vessels. JOURNAL OF CELL SCIENCE, 122(12), 2064-2077.The Company of Biologists. doi: 10.1242/jcs.048793.

Yates, C.C., Krisha, P., Whaley, D., Bodnar, R., Turner, T., & Wells, A. (2009). Scarring of dermal wounds in the absence of CXCR3 involves both the dermal and epidermal compartments. FASEB JOURNAL, 23.

Yates, C.C., Krisha, P., Whaley, D.W., Bodnar, R., Turner, T., & Wells, A. (2009). SCARRING OF DERMAL WOUNDS IN THE ABSENCE OF CXCR3 INVOLVES BOTH THE DERMAL AND EPIDERMAL COMPARTMENTS. WOUND REPAIR AND REGENERATION, 17(2), A18.

Yates, C.C., Shields, D., Rodgers, M., Jaynes, J., Wells, A., Bodnar, R., & Turner, T. (2009). IP-10 fragment is the functional motif that blocks endothelial cell motility and vessel formation. FASEB JOURNAL, 23.

Yates, C.C., Whaley, D., Hooda, S., Hebda, P.A., Bodnar, R.J., & Wells, A. (2009). Delayed reepithelialization and basement membrane regeneration after wounding in mice lacking CXCR3. WOUND REPAIR AND REGENERATION, 17(1), 34-41.Wiley. doi: 10.1111/j.1524-475X.2008.00439.x.

Bodnar, R.J., Yates, C.C., Du, X., & Wells, A. (2008). IP-10/CXCL10 mediated calpain cleavage of beta-3 integrin leads to the dissociation of newly-formed vessels during wound healing. WOUND REPAIR AND REGENERATION, 16(2), A20.

Bodnar, R.J., Yates, C.C., Du, X., & Wells, A. (2008). Modulation of Vessel Stability by the ELR-negative Chemokine IP-10. CIRCULATION, 118(18), S415.

Wells, A., Yates, C.C., Bodnar, R., Whaley, D., & Krishna, P. (2008). The end of the affair: CXCR3 ligands stop wound repair and limit scarring. WOUND REPAIR AND REGENERATION, 16(6), A67.

Yates, C.C., Whaley, D., Bodnar, R., & Wells, A. (2008). Loss of CXC chemokine receptor 3 signaling cause a delay in epidermal and dermal maturation and leads to hypertrophic scarring. FASEB JOURNAL, 22.

Yates, C.C., Whaley, D., Bodnar, R., & Wells, A. (2008). Loss of CXC chemokine receptor 3 signaling cause a delay in epidermal and dermal maturation and leads to hypertrophic scarring. WOUND REPAIR AND REGENERATION, 16(2), A52.

Yates, C.C., Whaley, D., Y-Chen, A., Kulesekaran, P., Hebda, P.A., & Wells, A. (2008). ELR-negative CXC chemokine CXCL11 (IP-9/I-TAC) facilitates dermal and epidermal maturation during wound repair. AMERICAN JOURNAL OF PATHOLOGY, 173(3), 643-652.Elsevier BV. doi: 10.2353/ajpath.2008.070990.

Whaley, D., Yates, C.C., Hancock, W.W., Lu, B., Newsome, J., Hebda, P.A., & Wells, A. (2007). CXCR3-/- mice display a dysfunction in basement membrane remodeling and delay in re-epithelialization during wound healing. WOUND REPAIR AND REGENERATION, 15(2), A48.

Yates, C.C., Shepard, C.R., Stolz, D.B., & Wells, A. (2007). Co-culturing human prostate carcinoma cells with hepatocytes leads to increased expression of E-cadherin. BRITISH JOURNAL OF CANCER, 96(8), 1246-1252.Springer Science and Business Media LLC. doi: 10.1038/sj.bjc.6603700.

Yates, C.C., Whaley, D., Babu, R., Zhang, J., Krishna, P., Beckman, E., Pasculle, A.W., & Wells, A. (2007). The effect of multifunctional polymer-based gels on wound healing in full thickness bacteria-contaminated mouse skin wound models. BIOMATERIALS, 28(27), 3977-3986.Elsevier BV. doi: 10.1016/j.biomaterials.2007.05.008.

Yates, C.C., Whaley, D., Hancock, W.W., Lu, B., Newsome, J., Hebda, P.A., Bodnar, R., & Wells, A. (2007). CXCR3-/- mice display a dysfunction in basement membrane remodeling and delay in re-epithelialization during wound healing. WOUND REPAIR AND REGENERATION, 15(6), A123.

Yates, C.C., Whaley, D., Kulasekaran, P., Newsome, J., Hebda, P., & Wells, A. (2007). The ELR-negative CXC chemokine CXCL11 ip-9 or i-tac) facilitates dermal and epidermal maturation during wound repair. WOUND REPAIR AND REGENERATION, 15(2), A17.

Yates, C.C., Whaley, D., Kulasekaran, P., Newsome, J., Hebda, P., & Wells, A. (2007). The ELR-negative CXC chemokine CXCL11 (IP-9 or I-TAC) facilitates dermal and epidermal maturation during wound repair. WOUND REPAIR AND REGENERATION, 15(6), A122.

Yates, C.C., Whaley, D., Kulasekeran, P., Hancock, W.W., Lu, B., Bodnar, R., Newsome, J., Hebda, P.A., & Wells, A. (2007). Delayed and deficient dermal maturation in mice lacking the CXCR3 ELR-negative CXC chemokine receptor. AMERICAN JOURNAL OF PATHOLOGY, 171(2), 484-495.Elsevier BV. doi: 10.2353/ajpath.2007.061092.

Bodnar, R.J., Yates, C.C., & Wells, A. (2006). IP-10 blocks vascular endothelial growth factor-induced endothelial cell motility and tube formation via inhibition of calpain. CIRCULATION RESEARCH, 98(5), 617-625.Ovid Technologies (Wolters Kluwer Health). doi: 10.1161/01.RES.0000209968.66606.10.

Bodnar, R.J., Yates, C.C., & Wells, A. (2006). IP-10 blocks VEGF-induced endothelial cell motility and tube formation via inhibition of calpain. FASEB JOURNAL, 20(5), A1080.

Bodnar, R.J., Yates, C.C., & Wells, A. (2005). IP-10 blocks VEGF-incluced endothelial cell motility and tube formation via inhibition of calpain. CIRCULATION, 112(17), U357.

Yates, C.C., Beer-Stolz, D., Griffith, L., & Wells, A. (2004). A bioreactor for direct visualization of prostate cancer progression. FASEB JOURNAL, 18(5), A1182.

Yates-Binder, C.C., Rodrigues, M., Whaley, D., & Wells, A. (2012). Transplantation of mesenchymal stem cells and fibroblasts in a bio-compatible matrix corrects defective dermal remodeling. Pathology Annual Scientific Retreat.Pittsburgh.

Research interests

Fibrosis
scleroderma
systemic sclerosis