Michel Modo

Tang, H., Dai, S., Zou, E.M., Liu, G., Ahearn, R., Krafty, R., Modo, M., & Zhan, L. (2024). Ex-Vivo Hippocampus Segmentation Using Diffusion-Weighted MRI. MATHEMATICS, 12(7), 940.MDPI. doi: 10.3390/math12070940.

Fountain, C., Ghuman, H., Paldino, M., Tamber, M., Panigrahy, A., & Modo, M. (2023). Acquisition and Analysis of Excised Neocortex from Pediatric Patients with Focal Cortical Dysplasia Using Mesoscale Diffusion MRI. Diagnostics (Basel), 13(9), 1529.MDPI. doi: 10.3390/diagnostics13091529.

Ji, X., Walczak, P., van Beusekom, H.M.M., Casas, A.I., Clarkson, A., Farr, T., Jolkkonen, J., Liang, Y., Modo, M.M., Rosado-de-Castro, P.H., Ruscher, K., Wang, Y.J., Wu, H., Zille, M., Li, S., & Boltze, J. (2023). Join us on an amazing journey towards next-generation treatments for CNS disorders: Launch of Neuroprotection, a new high-quality journal in translational neuroscience. Neuroprotection, 1(1), 5-8.Wiley. doi: 10.1002/nep3.8.

Liu, J., van Beusekom, H., Bu, X.L., Chen, G., Henrique Rosado de Castro, P., Chen, X., Chen, X., Clarkson, A.N., Farr, T.D., Fu, Y., Jia, J., Jolkkonen, J., Kim, W.S., Korhonen, P., Li, S., Liang, Y., Liu, G.H., Liu, G., Liu, Y.H., Malm, T., Mao, X., Oliveira, J.M., Modo, M.M., Ramos-Cabrer, P., Ruscher, K., Song, W., Wang, J., Wang, X., Wang, Y., Wu, H., Xiong, L., Yang, Y., Ye, K., Yu, J.T., Zhou, X.F., Zille, M., Masters, C.L., Walczak, P., Boltze, J., Ji, X., & Wang, Y.J. (2023). Preserving cognitive function in patients with Alzheimer's disease: The Alzheimer's disease neuroprotection research initiative (ADNRI). Neuroprotection, 1(2), 84-98.Wiley. doi: 10.1002/nep3.23.

Manivannan, A., Foley, L.M., Hitchens, T.K., Rattray, I., Bates, G.P., & Modo, M. (2023). Ex vivo 100 μm isotropic diffusion MRI-based tractography of connectivity changes in the end-stage R6/2 mouse model of Huntington's disease. Neuroprotection, 1(1), 66-83.Wiley. doi: 10.1002/nep3.14.

Mcgraw, M., Gilmer, G., Bergmann, J., Seshan, V., Wang, K., Pekker, D., Modo, M., & Ambrosio, F. (2023). Mapping the Landscape of Magnetic Field Effects on Neural Regeneration and Repair: A Combined Systematic Review, Mathematical Model, and Meta-Analysis. In Stabler, C.L. (Ed.). JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2023(1), 1-15.Hindawi. doi: 10.1155/2023/5038317.

Modo, M., Fink, K., & Rossignol, J. (2023). Biologics in brain repair. Brain Res Bull, 202, 110757.Elsevier. doi: 10.1016/j.brainresbull.2023.110757.

Modo, M., Sparling, K., Novotny, J., Perry, N., Foley, L.M., & Hitchens, T.K. (2023). Mapping mesoscale connectivity within the human hippocampus. Neuroimage, 282, 120406.Elsevier. doi: 10.1016/j.neuroimage.2023.120406.

Ghuman, H., Perry, N., Grice, L., Gerwig, M., Moorhead, J., Nitzsche, F., Poplawsky, A.J., Ambrosio, F., & Modo, M. (2022). Physical therapy exerts sub-additive and suppressive effects on intracerebral neural stem cell implantation in a rat model of stroke. J Cereb Blood Flow Metab, 42(5), 826-843.SAGE Publications. doi: 10.1177/0271678X211062955.

Modo, M., Ghuman, H., Azar, R., Krafty, R., Badylak, S.F., & Hitchens, T.K. (2022). Mapping the acute time course of immune cell infiltration into an ECM hydrogel in a rat model of stroke using 19F MRI. Biomaterials, 282, 121386.Elsevier. doi: 10.1016/j.biomaterials.2022.121386.

Modo, M., Lampe, K., & Willerth, S. (2022). Engineering brain and spinal cord tissue constructs. Brain Res Bull, 178, 131-132.Elsevier. doi: 10.1016/j.brainresbull.2021.11.012.

Damian, C., Ghuman, H., Mauney, C., Azar, R., Reinartz, J., Badylak, S.F., & Modo, M. (2021). Post-Stroke Timing of ECM Hydrogel Implantation Affects Biodegradation and Tissue Restoration. Int J Mol Sci, 22(21), 11372.MDPI. doi: 10.3390/ijms222111372.

Ghuman, H., Matta, R., Tompkins, A., Nitzsche, F., Badylak, S.F., Gonzalez, A.L., & Modo, M. (2021). ECM hydrogel improves the delivery of PEG microsphere-encapsulated neural stem cells and endothelial cells into tissue cavities caused by stroke. Brain Res Bull, 168, 120-137.Elsevier. doi: 10.1016/j.brainresbull.2020.12.004.

Hussein, H., Kokkinos, V., Sisterson, N.D., Modo, M., & Richardson, R.M. (2021). Extrapial Hippocampal Resection in Anterior Temporal Lobectomy: Technical Description and Clinical Outcomes in a 62-Patient Case Series. Oper Neurosurg (Hagerstown), 21(5), 312-323.Wolters Kluwer. doi: 10.1093/ons/opab262.

Modo, M. (2021). 19F Magnetic Resonance Imaging and Spectroscopy in Neuroscience. Neuroscience, 474, 37-50.Elsevier. doi: 10.1016/j.neuroscience.2021.03.016.

Chou, C.H., & Modo, M. (2020). Characterization of gene expression changes in human neural stem cells and endothelial cells modeling a neurovascular microenvironment. Brain Res Bull, 158, 9-19.Elsevier. doi: 10.1016/j.brainresbull.2020.02.008.

Ke, J., Foley, L.M., Hitchens, T.K., Richardson, R.M., & Modo, M. (2020). Ex vivo mesoscopic diffusion MRI correlates with seizure frequency in patients with uncontrolled mesial temporal lobe epilepsy. Hum Brain Mapp, 41(16), 4529-4548.Wiley. doi: 10.1002/hbm.25139.

Ke, J., Foley, L.M., Hitchens, T.K., Richardson, R.M., & Modo, M. (2020). Cover Image. Human Brain Mapping, 41(16).Wiley. doi: 10.1002/hbm.24671.

Ly, M., Foley, L., Manivannan, A., Hitchens, T.K., Richardson, R.M., & Modo, M. (2020). Mesoscale diffusion magnetic resonance imaging of the ex vivo human hippocampus. Hum Brain Mapp, 41(15), 4200-4218.Wiley. doi: 10.1002/hbm.25119.

Ly, M., Foley, L., Manivannan, A., Hitchens, T.K., Richardson, R.M., & Modo, M. (2020). Cover Image. Human Brain Mapping, 41(15).Wiley. doi: 10.1002/hbm.24669.

Boltze, J., Modo, M.M., Mays, R.W., Taguchi, A., Jolkkonen, J., Savitz, S.I., & STEPS 4 Consortium. (2019). Stem Cells as an Emerging Paradigm in Stroke 4: Advancing and Accelerating Preclinical Research. Stroke, 50(11), 3299-3306.Wolters Kluwer. doi: 10.1161/STROKEAHA.119.025436.

Ghuman, H., Hitchens, T.K., & Modo, M. (2019). A systematic optimization of 19F MR image acquisition to detect macrophage invasion into an ECM hydrogel implanted in the stroke-damaged brain. Neuroimage, 202, 116090.Elsevier. doi: 10.1016/j.neuroimage.2019.116090.

Modo, M. (2019). Bioscaffold-Induced Brain Tissue Regeneration. Front Neurosci, 13, 1156.Frontiers. doi: 10.3389/fnins.2019.01156.

Modo, M., & Badylak, S.F. (2019). A roadmap for promoting endogenous in situ tissue restoration using inductive bioscaffolds after acute brain injury. Brain Res Bull, 150, 136-149.Elsevier. doi: 10.1016/j.brainresbull.2019.05.013.

Modo, M., & Lampe, K. (2019). Development and implementation of biomaterials to promote neural repair. Brain Res Bull, 152, 297-298.Elsevier. doi: 10.1016/j.brainresbull.2019.07.026.

Calevro, A., Cotel, M.C., Natesan, S., Modo, M., Vernon, A.C., & Mondelli, V. (2018). Effects of chronic antipsychotic drug exposure on the expression of Translocator Protein and inflammatory markers in rat adipose tissue. Psychoneuroendocrinology, 95, 28-33.Elsevier. doi: 10.1016/j.psyneuen.2018.05.021.

Ghuman, H., Mauney, C., Donnelly, J., Massensini, A.R., Badylak, S.F., & Modo, M. (2018). Biodegradation of ECM hydrogel promotes endogenous brain tissue restoration in a rat model of stroke. Acta Biomater, 80, 66-84.Elsevier. doi: 10.1016/j.actbio.2018.09.020.

Jin, T., Iordanova, B., Hitchens, T.K., Modo, M., Wang, P., Mehrens, H., & Kim, S.G. (2018). Chemical exchange-sensitive spin-lock (CESL) MRI of glucose and analogs in brain tumors. Magn Reson Med, 80(2), 488-495.Wiley. doi: 10.1002/mrm.27183.

Liu, J.R., & Modo, M. (2018). Quantification of the Extracellular Matrix Molecule Thrombospondin 1 and Its Pericellular Association in the Brain Using a Semiautomated Computerized Approach. J Histochem Cytochem, 66(9), 643-662.SAGE Publications. doi: 10.1369/0022155418771677.

Modo, M.M., Jolkkonen, J., Zille, M., & Boltze, J. (2018). Future of Animal Modeling for Poststroke Tissue Repair. Stroke, 49(5), 1099-1106.Wolters Kluwer. doi: 10.1161/STROKEAHA.117.018293.

Wahlberg, B., Ghuman, H., Liu, J.R., & Modo, M. (2018). Ex vivo biomechanical characterization of syringe-needle ejections for intracerebral cell delivery. Sci Rep, 8(1), 9194.Springer Nature. doi: 10.1038/s41598-018-27568-x.

Bulte, J.W.M., & Modo, M.M.J. (2017). Design and Applications of Nanoparticles in Biomedical Imaging. In Bulte, J.W.M., & Modo, M.M.J. (Eds.). v.Springer International Publishing. doi: 10.1007/978-3-319-42169-8.

Bulte, J.W.M., & Modo, M.M.J. (2017). Nanoparticles as a Technology Platform for Biomedical Imaging. In Design and Applications of Nanoparticles in Biomedical Imaging. (pp. 1-7).Springer Nature. doi: 10.1007/978-3-319-42169-8_1.

Dalise, S., Cavalli, L., Ghuman, H., Wahlberg, B., Gerwig, M., Chisari, C., Ambrosio, F., & Modo, M. (2017). Biological effects of dosing aerobic exercise and neuromuscular electrical stimulation in rats. Sci Rep, 7(1), 10830.Springer Nature. doi: 10.1038/s41598-017-11260-7.

Ghuman, H., Gerwig, M., Nicholls, F.J., Liu, J.R., Donnelly, J., Badylak, S.F., & Modo, M. (2017). Long-term retention of ECM hydrogel after implantation into a sub-acute stroke cavity reduces lesion volume. Acta Biomater, 63, 50-63.Elsevier. doi: 10.1016/j.actbio.2017.09.011.

Jin, T., Nicholls, F.J., Crum, W.R., Ghuman, H., Badylak, S.F., & Modo, M. (2017). Diamagnetic chemical exchange saturation transfer (diaCEST) affords magnetic resonance imaging of extracellular matrix hydrogel implantation in a rat model of stroke. Biomaterials, 113, 176-190.Elsevier. doi: 10.1016/j.biomaterials.2016.10.043.

Modo, M., Crum, W.R., Gerwig, M., Vernon, A.C., Patel, P., Jackson, M.J., Rose, S., Jenner, P., & Iravani, M.M. (2017). Magnetic resonance imaging and tensor-based morphometry in the MPTP non-human primate model of Parkinson's disease. In Smeyne, R.J. (Ed.). PLoS One, 12(7), e0180733.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0180733.

Nicholls, F.J., Liu, J.R., & Modo, M. (2017). A Comparison of Exogenous Labels for the Histological Identification of Transplanted Neural Stem Cells. Cell Transplant, 26(4), 625-645.SAGE Publications. doi: 10.3727/096368916X693680.

Rattray, I., Smith, E.J., Crum, W.R., Walker, T.A., Gale, R., Bates, G.P., & Modo, M. (2017). Correlations of Behavioral Deficits with Brain Pathology Assessed through Longitudinal MRI and Histopathology in the HdhQ150/Q150 Mouse Model of Huntington's Disease. In Planel, E. (Ed.). PLoS One, 12(1), e0168556.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0168556.

Chou, C.H., & Modo, M. (2016). Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling. Sci Rep, 6, 29029. doi: 10.1038/srep29029.

Crum, W.R., Danckaers, F., Huysmans, T., Cotel, M.C., Natesan, S., Modo, M.M., Sijbers, J., Williams, S.C.R., Kapur, S., & Vernon, A.C. (2016). Chronic exposure to haloperidol and olanzapine leads to common and divergent shape changes in the rat hippocampus in the absence of grey-matter volume loss. Psychol Med, 46(15), 3081-3093.Cambridge University Press (CUP). doi: 10.1017/S0033291716001768.

Ghuman, H., & Modo, M. (2016). Biomaterial applications in neural therapy and repair. Chinese Neurosurgical Journal, 2(1), 34.Springer Nature. doi: 10.1186/s41016-016-0057-0.

Ghuman, H., Massensini, A.R., Donnelly, J., Kim, S.M., Medberry, C.J., Badylak, S.F., & Modo, M. (2016). ECM hydrogel for the treatment of stroke: Characterization of the host cell infiltrate. Biomaterials, 91, 166-181.Elsevier. doi: 10.1016/j.biomaterials.2016.03.014.

Modo, M. (2016). Gaining Mechanistic Insights into Cell Therapy Using Magnetic Resonance Imaging. Current Stem Cell Reports, 2(3), 221-227.Springer Nature. doi: 10.1007/s40778-016-0059-z.

Modo, M., Hitchens, T.K., Liu, J.R., & Richardson, R.M. (2016). Detection of aberrant hippocampal mossy fiber connections: Ex vivo mesoscale diffusion MRI and microtractography with histological validation in a patient with uncontrolled temporal lobe epilepsy. Hum Brain Mapp, 37(2), 780-795.Wiley. doi: 10.1002/hbm.23066.

Nicholls, F.J., Rotz, M.W., Ghuman, H., MacRenaris, K.W., Meade, T.J., & Modo, M. (2016). DNA-gadolinium-gold nanoparticles for in vivo T1 MR imaging of transplanted human neural stem cells. Biomaterials, 77, 291-306.Elsevier. doi: 10.1016/j.biomaterials.2015.11.021.

To, A.C. (2016). Preface. 12, 143.Elsevier. doi: 10.1016/j.addma.2016.09.003.

Caron, I., Micotti, E., Paladini, A., Merlino, G., Plebani, L., Forloni, G., Modo, M., & Bendotti, C. (2015). Comparative Magnetic Resonance Imaging and Histopathological Correlates in Two SOD1 Transgenic Mouse Models of Amyotrophic Lateral Sclerosis. In Grierson, A.J. (Ed.). PLoS One, 10(7), e0132159.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0132159.

Cotel, M.C., Lenartowicz, E.M., Natesan, S., Modo, M.M., Cooper, J.D., Williams, S.C.R., Kapur, S., & Vernon, A.C. (2015). Microglial activation in the rat brain following chronic antipsychotic treatment at clinically relevant doses. Eur Neuropsychopharmacol, 25(11), 2098-2107.Elsevier. doi: 10.1016/j.euroneuro.2015.08.004.

Massensini, A.R., Ghuman, H., Saldin, L.T., Medberry, C.J., Keane, T.J., Nicholls, F.J., Velankar, S.S., Badylak, S.F., & Modo, M. (2015). Concentration-dependent rheological properties of ECM hydrogel for intracerebral delivery to a stroke cavity. Acta Biomater, 27, 116-130.Elsevier. doi: 10.1016/j.actbio.2015.08.040.

Modo, M., Braga, R., & Ray, H.L. (2015). In Vivo Imaging of Transplanted Cells and Biomaterials. In Stem Cell Biology and Tissue Engineering in Dental Sciences. (pp. 841-851).Elsevier. doi: 10.1016/b978-0-12-397157-9.00069-2.

Naumova, A.V., Modo, M., Moore, A., Frank, J.A., & Murry, C.E. (2015). Response to cardiac regeneration validated. Nat Biotechnol, 33(6), 587.Springer Nature. doi: 10.1038/nbt.3257.

Nicholls, F.J., Ling, W., Ferrauto, G., Aime, S., & Modo, M. (2015). Simultaneous MR imaging for tissue engineering in a rat model of stroke. Sci Rep, 5(1), 14597.Springer Nature. doi: 10.1038/srep14597.

Chou, C.H., Sinden, J.D., Couraud, P.O., & Modo, M. (2014). In vitro modeling of the neurovascular environment by coculturing adult human brain endothelial cells with human neural stem cells. In Walczak, P. (Ed.). PLoS One, 9(9), e106346.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0106346.

Dalise, S., Ambrosio, F., & Modo, M. (2014). Adaptive plasticity and recovery in preclinical models of stroke. ARCHIVES ITALIENNES DE BIOLOGIE, 152(4), 190-215.Pisa University Press. doi: 10.12871/00039829201442.

Dalise, S., Ambrosio, F., & Modo, M. (2014). Brain plasticity and recovery in preclinical models of stroke. Arch Ital Biol, 152(4), 190-215. doi: 10.12871/00039829201442.

Meng, F., Modo, M., & Badylak, S.F. (2014). Biologic scaffold for CNS repair. Regen Med, 9(3), 367-383.Taylor & Francis. doi: 10.2217/rme.14.9.

Naumova, A.V., Modo, M., Moore, A., Murry, C.E., & Frank, J.A. (2014). Clinical imaging in regenerative medicine. Nat Biotechnol, 32(8), 804-818.Springer Nature. doi: 10.1038/nbt.2993.

Puppi, J., Modo, M., Dhawan, A., Lehec, S.C., Mitry, R.R., & Hughes, R.D. (2014). Ex vivo magnetic resonance imaging of transplanted hepatocytes in a rat model of acute liver failure. Cell Transplant, 23(3), 329-343.SAGE Publications. doi: 10.3727/096368913X663596.

Savitz, S.I., Cramer, S.C., Wechsler, L., & STEPS 3 Consortium. (2014). Stem cells as an emerging paradigm in stroke 3: enhancing the development of clinical trials. Stroke, 45(2), 634-639.Wolters Kluwer. doi: 10.1161/STROKEAHA.113.003379.

Vernon, A.C., Crum, W.R., Lerch, J.P., Chege, W., Natesan, S., Modo, M., Cooper, J.D., Williams, S.C.R., & Kapur, S. (2014). Reduced cortical volume and elevated astrocyte density in rats chronically treated with antipsychotic drugs-linking magnetic resonance imaging findings to cellular pathology. Biol Psychiatry, 75(12), 982-990.Elsevier. doi: 10.1016/j.biopsych.2013.09.012.

Alfieri, A., Srivastava, S., Siow, R.C.M., Cash, D., Modo, M., Duchen, M.R., Fraser, P.A., Williams, S.C.R., & Mann, G.E. (2013). Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood-brain barrier disruption and neurological deficits in stroke. Free Radic Biol Med, 65, 1012-1022.Elsevier. doi: 10.1016/j.freeradbiomed.2013.08.190.

Chou, C.H., Nicholls, F., & Modo, M. (2013). Image-Guided Injection and Noninvasive Monitoring of Tissue Regeneration in the Stroke-Damaged Brain. In Cell-Based Therapies in Stroke. (pp. 93-104).Springer Nature. doi: 10.1007/978-3-7091-1175-8_7.

Chung, Y.L., El Akabawy, G., So, P.W., Solanky, B.S., Leach, M.O., & Modo, M. (2013). Profiling metabolite changes in the neuronal differentiation of human striatal neural stem cells using 1H-magnetic resonance spectroscopy. Neuroreport, 24(18), 1035-1040.Wolters Kluwer. doi: 10.1097/WNR.0000000000000056.

Crum, W.R., Giampietro, V.P., Smith, E.J., Gorenkova, N., Stroemer, R.P., & Modo, M. (2013). A comparison of automated anatomical-behavioural mapping methods in a rodent model of stroke. J Neurosci Methods, 218(2), 170-183.Elsevier. doi: 10.1016/j.jneumeth.2013.05.009.

Crum, W.R., Modo, M., Vernon, A.C., Barker, G.J., & Williams, S.C.R. (2013). Registration of challenging pre-clinical brain images. J Neurosci Methods, 216(1), 62-77.Elsevier. doi: 10.1016/j.jneumeth.2013.03.015.

Dell'Acqua, F., Bodi, I., Slater, D., Catani, M., & Modo, M. (2013). MR diffusion histology and micro-tractography reveal mesoscale features of the human cerebellum. Cerebellum, 12(6), 923-931.Springer Nature. doi: 10.1007/s12311-013-0503-x.

Kazanis, I., Gorenkova, N., Zhao, J.W., Franklin, R.J.M., Modo, M., & Ffrench-Constant, C. (2013). The late response of rat subependymal zone stem and progenitor cells to stroke is restricted to directly affected areas of their niche. Exp Neurol, 248, 387-397.Elsevier. doi: 10.1016/j.expneurol.2013.06.025.

Medberry, C.J., Crapo, P.M., Siu, B.F., Carruthers, C.A., Wolf, M.T., Nagarkar, S.P., Agrawal, V., Jones, K.E., Kelly, J., Johnson, S.A., Velankar, S.S., Watkins, S.C., Modo, M., & Badylak, S.F. (2013). Hydrogels derived from central nervous system extracellular matrix. Biomaterials, 34(4), 1033-1040.Elsevier. doi: 10.1016/j.biomaterials.2012.10.062.

Modo, M., Ambrosio, F., Friedlander, R.M., Badylak, S.F., & Wechsler, L.R. (2013). Bioengineering solutions for neural repair and recovery in stroke. Curr Opin Neurol, 26(6), 626-631.Wolters Kluwer. doi: 10.1097/WCO.0000000000000031.

Modo, M., Kolosnjaj-Tabi, J., Nicholls, F., Ling, W., Wilhelm, C., Debarge, O., Gazeau, F., & Clement, O. (2013). Considerations for the clinical use of contrast agents for cellular MRI in regenerative medicine. Contrast Media Mol Imaging, 8(6), 439-455.Wiley. doi: 10.1002/cmmi.1547.

Mondelli, V., Anacker, C., Vernon, A.C., Cattaneo, A., Natesan, S., Modo, M., Dazzan, P., Kapur, S., & Pariante, C.M. (2013). Haloperidol and olanzapine mediate metabolic abnormalities through different molecular pathways. Transl Psychiatry, 3(1), e208.Springer Nature. doi: 10.1038/tp.2012.138.

Rattray, I., Smith, E., Gale, R., Matsumoto, K., Bates, G.P., & Modo, M. (2013). Correlations of behavioral deficits with brain pathology assessed through longitudinal MRI and histopathology in the R6/2 mouse model of HD. In Planel, E. (Ed.). PLoS One, 8(4), e60012.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0060012.

Rattray, I., Smith, E.J., Crum, W.R., Walker, T.A., Gale, R., Bates, G.P., & Modo, M. (2013). Correlations of behavioral deficits with brain pathology assessed through longitudinal MRI and histopathology in the R6/1 mouse model of Huntington's disease. In Borchelt, D.R. (Ed.). PLoS One, 8(12), e84726.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0084726.

Stille, M., Smith, E.J., Crum, W.R., & Modo, M. (2013). 3D reconstruction of 2D fluorescence histology images and registration with in vivo MR images: application in a rodent stroke model. J Neurosci Methods, 219(1), 27-40.Elsevier. doi: 10.1016/j.jneumeth.2013.06.003.

Bible, E., Dell'Acqua, F., Solanky, B., Balducci, A., Crapo, P.M., Badylak, S.F., Ahrens, E.T., & Modo, M. (2012). Non-invasive imaging of transplanted human neural stem cells and ECM scaffold remodeling in the stroke-damaged rat brain by (19)F- and diffusion-MRI. Biomaterials, 33(10), 2858-2871.Elsevier. doi: 10.1016/j.biomaterials.2011.12.033.

Bible, E., Qutachi, O., Chau, D.Y.S., Alexander, M.R., Shakesheff, K.M., & Modo, M. (2012). Neo-vascularization of the stroke cavity by implantation of human neural stem cells on VEGF-releasing PLGA microparticles. Biomaterials, 33(30), 7435-7446.Elsevier. doi: 10.1016/j.biomaterials.2012.06.085.

El-Akabawy, G., Rattray, I., Johansson, S.M., Gale, R., Bates, G., & Modo, M. (2012). Implantation of undifferentiated and pre-differentiated human neural stem cells in the R6/2 transgenic mouse model of Huntington's disease. BMC Neurosci, 13(1), 97.Springer Nature. doi: 10.1186/1471-2202-13-97.

Evans, M.C., Modo, M., Talbot, K., Sibson, N., & Turner, M.R. (2012). Magnetic resonance imaging of pathological processes in rodent models of amyotrophic lateral sclerosis. Amyotroph Lateral Scler, 13(3), 288-301.Taylor & Francis. doi: 10.3109/17482968.2011.623300.

Patkar, S., Tate, R., Modo, M., Plevin, R., & Carswell, H.V.O. (2012). Conditionally immortalised neural stem cells promote functional recovery and brain plasticity after transient focal cerebral ischaemia in mice. Stem Cell Res, 8(1), 14-25.Elsevier. doi: 10.1016/j.scr.2011.07.001.

Smith, E.J., Stroemer, R.P., Gorenkova, N., Nakajima, M., Crum, W.R., Tang, E., Stevanato, L., Sinden, J.D., & Modo, M. (2012). Implantation site and lesion topology determine efficacy of a human neural stem cell line in a rat model of chronic stroke. Stem Cells, 30(4), 785-796.Oxford University Press (OUP). doi: 10.1002/stem.1024.

Sztriha, L.K., O'Gorman, R.L., Modo, M., Barker, G.J., Williams, S.C.R., & Kalra, L. (2012). Monitoring brain repair in stroke using advanced magnetic resonance imaging. Stroke, 43(11), 3124-3131.Wolters Kluwer. doi: 10.1161/STROKEAHA.111.649244.

Vernon, A.C., & Modo, M. (2012). Do levodopa treatments modify the morphology of the parkinsonian brain?. Mov Disord, 27(1), 166-167.Wiley. doi: 10.1002/mds.24018.

Vernon, A.C., Natesan, S., Crum, W.R., Cooper, J.D., Modo, M., Williams, S.C.R., & Kapur, S. (2012). Contrasting effects of haloperidol and lithium on rodent brain structure: a magnetic resonance imaging study with postmortem confirmation. Biol Psychiatry, 71(10), 855-863.Elsevier. doi: 10.1016/j.biopsych.2011.12.004.

Vernon, A.C., Natesan, S., Crum, W.R., Modo, M., Cooper, J.D., Williams, S.C.R., & Kapur, S. (2012). Reply to: Lithium and the Expanding Brain. BIOLOGICAL PSYCHIATRY, 72(7), E19.Elsevier. doi: 10.1016/j.biopsych.2012.04.007.

Alfieri, A., Srivastava, S., Siow, R.C.M., Modo, M., Fraser, P.A., & Mann, G.E. (2011). Targeting the Nrf2-Keap1 antioxidant defence pathway for neurovascular protection in stroke. J Physiol, 589(17), 4125-4136.Wiley. doi: 10.1113/jphysiol.2011.210294.

El-Akabawy, G., Medina, L.M., Jeffries, A., Price, J., & Modo, M. (2011). Purmorphamine increases DARPP-32 differentiation in human striatal neural stem cells through the Hedgehog pathway. Stem Cells Dev, 20(11), 1873-1887.Mary Ann Liebert. doi: 10.1089/scd.2010.0282.

Kateb, B., Chiu, K., Black, K.L., Yamamoto, V., Khalsa, B., Ljubimova, J.Y., Ding, H., Patil, R., Portilla-Arias, J.A., Modo, M., Moore, D.F., Farahani, K., Okun, M.S., Prakash, N., Neman, J., Ahdoot, D., Grundfest, W., Nikzad, S., & Heiss, J.D. (2011). Nanoplatforms for constructing new approaches to cancer treatment, imaging, and drug delivery: what should be the policy?. Neuroimage, 54 Suppl 1(Suppl 1), S106-S124.Elsevier. doi: 10.1016/j.neuroimage.2010.01.105.

Modo, M. (2011). Tracking transplanted cells by MRI - methods and protocols. Methods Mol Biol, 771, 717-732.Springer Nature. doi: 10.1007/978-1-61779-219-9_35.

Modo, M., & Bulte, J.W.M. (2011). From molecules to man: the dawn of a vitreous man. Methods Mol Biol, 711, 3-14.Springer Nature. doi: 10.1007/978-1-61737-992-5_1.

Modo, M., & Kinchin, I. (2011). A conceptual framework for interdisciplinary curriculum design: a case study in neuroscience. J Undergrad Neurosci Educ, 10(1), A71-A79.

Puppi, J., Mitry, R.R., Modo, M., Dhawan, A., Raja, K., & Hughes, R.D. (2011). Use of a clinically approved iron oxide MRI contrast agent to label human hepatocytes. Cell Transplant, 20(6), 963-975.SAGE Publications. doi: 10.3727/096368910X543367.

Vernon, A.C., & Modo, M. (2011). Non-invasive MR imaging of neurodegeneration in a rodent model of Parkinson's disease. Methods Mol Biol, 711, 487-510.Springer Nature. doi: 10.1007/978-1-61737-992-5_25.

Vernon, A.C., Crum, W.R., Johansson, S.M., & Modo, M. (2011). Evolution of extra-nigral damage predicts behavioural deficits in a rat proteasome inhibitor model of Parkinson's disease. In Cookson, M. (Ed.). PLoS One, 6(2), e17269.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0017269.

Vernon, A.C., Natesan, S., Modo, M., & Kapur, S. (2011). Effect of chronic antipsychotic treatment on brain structure: a serial magnetic resonance imaging study with ex vivo and postmortem confirmation. Biol Psychiatry, 69(10), 936-944.Elsevier. doi: 10.1016/j.biopsych.2010.11.010.

Vernon, A.C., Smith, E.J., Stevanato, L., & Modo, M. (2011). Selective activation of metabotropic glutamate receptor 7 induces inhibition of cellular proliferation and promotes astrocyte differentiation of ventral mesencephalon human neural stem/progenitor cells. Neurochem Int, 59(3), 421-431.Elsevier. doi: 10.1016/j.neuint.2011.04.001.

Turner, M.R., & Modo, M. (2010). Advances in the application of MRI to amyotrophic lateral sclerosis. Expert Opin Med Diagn, 4(6), 483-496.Taylor & Francis. doi: 10.1517/17530059.2010.536836.

Vernon, A.C., Ballard, C., & Modo, M. (2010). Neuroimaging for Lewy body disease: is the in vivo molecular imaging of α-synuclein neuropathology required and feasible?. Brain Res Rev, 65(1), 28-55.Elsevier. doi: 10.1016/j.brainresrev.2010.05.006.

Vernon, A.C., Johansson, S.M., & Modo, M.M. (2010). Non-invasive evaluation of nigrostriatal neuropathology in a proteasome inhibitor rodent model of Parkinson's disease. BMC Neurosci, 11(1), 1.Springer Nature. doi: 10.1186/1471-2202-11-1.

Ashioti, M., Beech, J.S., Lowe, A.S., Bernanos, M., McCreary, A., Modo, M.M., & Williams, S.C.R. (2009). Neither in vivo MRI nor behavioural assessment indicate therapeutic efficacy for a novel 5HT(1A) agonist in rat models of ischaemic stroke. BMC Neurosci, 10(1), 82.Springer Nature. doi: 10.1186/1471-2202-10-82.

Badin, R.A., Modo, M., Cheetham, M., Thomas, D.L., Gadian, D.G., Latchman, D.S., & Lythgoe, M.F. (2009). Protective effect of post-ischaemic viral delivery of heat shock proteins in vivo. J Cereb Blood Flow Metab, 29(2), 254-263.SAGE Publications. doi: 10.1038/jcbfm.2008.106.

Bible, E., Chau, D.Y.S., Alexander, M.R., Price, J., Shakesheff, K.M., & Modo, M. (2009). Attachment of stem cells to scaffold particles for intra-cerebral transplantation. Nat Protoc, 4(10), 1440-1453.Springer Nature. doi: 10.1038/nprot.2009.156.

Bible, E., Chau, D.Y.S., Alexander, M.R., Price, J., Shakesheff, K.M., & Modo, M. (2009). The support of neural stem cells transplanted into stroke-induced brain cavities by PLGA particles. Biomaterials, 30(16), 2985-2994.Elsevier. doi: 10.1016/j.biomaterials.2009.02.012.

Modo, M., Beech, J.S., Meade, T.J., Williams, S.C.R., & Price, J. (2009). A chronic 1 year assessment of MRI contrast agent-labelled neural stem cell transplants in stroke. Neuroimage, 47 Suppl 2(0 2), T133-T142.Elsevier. doi: 10.1016/j.neuroimage.2008.06.017.

Modo, M., Meade, T.J., & Mitry, R.R. (2009). Liver cell labelling with MRI contrast agents. Methods Mol Biol, 481, 207-219.Springer Nature. doi: 10.1007/978-1-59745-201-4_17.

Modo, M., Meade, T.J., & Mitry, R.R. (2009). Liver cell labelling with MRI contrast agents. Methods in molecular biology (Clifton, N.J.), 481, 207-219.

Puppi, J., & Modo, M. (2009). Use of magnetic resonance imaging contrast agents to detect transplanted liver cells. Top Magn Reson Imaging, 20(2), 113-120.Wolters Kluwer. doi: 10.1097/RMR.0b013e3181c0dfe4.

Johansson, S., Price, J., & Modo, M. (2008). Effect of inflammatory cytokines on major histocompatibility complex expression and differentiation of human neural stem/progenitor cells. Stem Cells, 26(9), 2444-2454.Oxford University Press (OUP). doi: 10.1634/stemcells.2008-0116.

Modo, M. (2008). Noninvasive imaging of transplanted cells. Curr Opin Organ Transplant, 13(6), 654-658.Wolters Kluwer. doi: 10.1097/MOT.0b013e328317a43c.

Modo, M. (2008). Brain repair how stem cells are changing neurology. Bull Soc Sci Med Grand Duche Luxemb, (2), 217-257.

Roberts, T.J., Williams, S.C.R., & Modo, M. (2008). A pharmacological MRI assessment of dizocilpine (MK-801) in the 3-nitroproprionic acid-lesioned rat. Neurosci Lett, 444(1), 42-47.Elsevier. doi: 10.1016/j.neulet.2008.07.090.

Ashioti, M., Beech, J.S., Lowe, A.S., Hesselink, M.B., Modo, M., & Williams, S.C.R. (2007). Multi-modal characterisation of the neocortical clip model of focal cerebral ischaemia by MRI, behaviour and immunohistochemistry. Brain Res, 1145(1), 177-189.Elsevier. doi: 10.1016/j.brainres.2007.01.111.

Bae, J.S., Han, H.S., Youn, D.H., Carter, J.E., Modo, M., Schuchman, E.H., & Jin, H.K. (2007). Bone marrow-derived mesenchymal stem cells promote neuronal networks with functional synaptic transmission after transplantation into mice with neurodegeneration. Stem Cells, 25(5), 1307-1316.Oxford University Press (OUP). doi: 10.1634/stemcells.2006-0561.

Brekke, C., Morgan, S.C., Lowe, A.S., Meade, T.J., Price, J., Williams, S.C.R., & Modo, M. (2007). The in vitro effects of a bimodal contrast agent on cellular functions and relaxometry. NMR Biomed, 20(2), 77-89.Wiley. doi: 10.1002/nbm.1077.

Brekke, C., Williams, S.C., Price, J., Thorsen, F., & Modo, M. (2007). Cellular multiparametric MRI of neural stem cell therapy in a rat glioma model. Neuroimage, 37(3), 769-782.Elsevier. doi: 10.1016/j.neuroimage.2007.06.006.

Modo, M.M.J., & Bulte, J.W.M. (2007). Cellular imaging of cell transplants. In Molecular and Cellular MR Imaging. (pp. 325-341).

Modo, M.M.J., & Bulte, J.W.M. (2007). An outlook on molecular and cellular MR imaging. In Molecular and Cellular MR Imaging. (pp. 405-409).

Modo, M.M.J., & Bulte, J.W.M. (2007). Molecular and cellular MR imaging. 1-443.

Modo, M.M.J., & Bulte, J.W.M. (2007). What is molecular and cellular imaging?. In Molecular and Cellular MR Imaging. (pp. 1-9).

Roberts, T.J., Price, J., Williams, S.C.R., & Modo, M. (2007). Pharmacological MRI of stem cell transplants in the 3-nitropropionic acid-damaged striatum. Neuroscience, 144(1), 100-109.Elsevier. doi: 10.1016/j.neuroscience.2006.09.015.

Schaller, B.J., Modo, M., & Buchfelder, M. (2007). Molecular imaging of brain tumors: a bridge between clinical and molecular medicine?. Mol Imaging Biol, 9(2), 60-71.Springer Nature. doi: 10.1007/s11307-006-0069-9.

Wheatcroft, S.B., Kearney, M.T., Shah, A.M., Ezzat, V.A., Miell, J.R., Modo, M., Williams, S.C.R., Cawthorn, W.P., Medina-Gomez, G., Vidal-Puig, A., Sethi, J.K., & Crossey, P.A. (2007). IGF-binding protein-2 protects against the development of obesity and insulin resistance. Diabetes, 56(2), 285-294.American Diabetes Association. doi: 10.2337/db06-0436.

Fromes, Y., Modo, M., Herynek, V., Hoehn, M., Waerzeggers, Y., & Jacobs, A.H. (2006). Cellular Therapies and Cell Tracking. In Textbook ofin vivo Imaging in Vertebrates. (pp. 347-367).Wiley. doi: 10.1002/9780470029596.ch14.

Modo, M. (2006). Understanding stem cell-mediated brain repair through neuroimaging. Curr Stem Cell Res Ther, 1(1), 55-63.Bentham Science Publishers. doi: 10.2174/157488806775269106.

Roberts, T.J., Price, J., Williams, S.C.R., & Modo, M. (2006). Preservation of striatal tissue and behavioral function after neural stem cell transplantation in a rat model of Huntington's disease. Neuroscience, 139(4), 1187-1199.Elsevier. doi: 10.1016/j.neuroscience.2006.01.025.

Modo, M., Hoehn, M., & Bulte, J.W.M. (2005). Cellular MR imaging. Mol Imaging, 4(3), 143-164.SAGE Publications. doi: 10.1162/15353500200505145.

Modo, M., Mellodew, K., Cash, D., Fraser, S.E., Meade, T.J., Price, J., & Williams, S.C.R. (2004). Mapping transplanted stem cell migration after a stroke: a serial, in vivo magnetic resonance imaging study. Neuroimage, 21(1), 311-317.Elsevier. doi: 10.1016/j.neuroimage.2003.08.030.

Modo, M., Roberts, T.J., Sandhu, J.K., & Williams, S.C.R. (2004). In vivo monitoring of cellular transplants by magnetic resonance imaging and positron emission tomography. Expert Opin Biol Ther, 4(2), 145-155.Taylor & Francis. doi: 10.1517/14712598.4.2.145.

Modo, M., Roberts, T.J., Sandhu, J.K., & Williams, S.C.R. (2004). In vivo monitoring of cellular transplants by magnetic resonance imaging and positron emission tomography. EXPERT OPINION ON BIOLOGICAL THERAPY, 4(2), 145-155.Informa UK Limited. doi: 10.1517/eobt.4.2.145.26331.

Modo, M., Hopkins, K., Virley, D., & Hodges, H. (2003). Transplantation of neural stem cells modulates apolipoprotein E expression in a rat model of stroke. Exp Neurol, 183(2), 320-329.Elsevier. doi: 10.1016/s0014-4886(03)00059-1.

Modo, M., Mellodew, K., & Rezaie, P. (2003). In vitro expression of major histocompatibility class I and class II antigens by conditionally immortalized murine neural stem cells. Neurosci Lett, 337(2), 85-88.Elsevier. doi: 10.1016/s0304-3940(02)01301-0.

Modo, M., Stroemer, R.P., Tang, E., Patel, S., & Hodges, H. (2003). Effects of implantation site of dead stem cells in rats with stroke damage. Neuroreport, 14(1), 39-42.Wolters Kluwer. doi: 10.1097/00001756-200301200-00007.

Modo, M., Stroemer, R.P., Tang, E., Patel, S., & Hodges, H. (2003). Effects of implantation site of dead stem cells in rats with stroke damage. Neuroreport, 14(1), 39-42. doi: 10.1097/00001756-200301200-00007.

Modo, M. (2002). Tracking Transplanted Stem Cell Migration Using Bifunctional, Contrast Agent-Enhanced, Magnetic Resonance Imaging. NeuroImage, 17(2), 803-811.Elsevier BV. doi: 10.1016/s1053-8119(02)91194-8.

Modo, M., Cash, D., Mellodew, K., Williams, S.C.R., Fraser, S.E., Meade, T.J., Price, J., & Hodges, H. (2002). Tracking transplanted stem cell migration using bifunctional, contrast agent-enhanced, magnetic resonance imaging. Neuroimage, 17(2), 803-811.Elsevier. doi: 10.1006/nimg.2002.1194.

Modo, M., Cash, D., Mellodew, K., Williams, S.C.R., Fraser, S.E., Meade, T.J., Price, J., & Hodges, H. (2002). Tracking transplanted stem cell migration using bifunctional, contrast agent-enhanced, magnetic resonance imaging. NEUROIMAGE, 17(2), 803-811. doi: 10.1006/nimg.2002.1194.

Modo, M., Rezaie, P., Heuschling, P., Patel, S., Male, D.K., & Hodges, H. (2002). Transplantation of neural stem cells in a rat model of stroke: assessment of short-term graft survival and acute host immunological response. Brain Res, 958(1), 70-82.Elsevier. doi: 10.1016/s0006-8993(02)03463-7.

Modo, M., Stroemer, P., Tang, E., Patel, S., & Hodges, H. (2002). Effects of implantation site of stem cell grafts on behavioral recovery from stroke damage. STROKE, 33(9), 2270-2278. doi: 10.1161/01.STR.0000027693.50675.C5.

Modo, M., Stroemer, R.P., Tang, E., Patel, S., & Hodges, H. (2002). Effects of implantation site of stem cell grafts on behavioral recovery from stroke damage. Stroke, 33(9), 2270-2278.Wolters Kluwer. doi: 10.1161/01.str.0000027693.50675.c5.

Modo, M.M., & Williams, S.C.R. (2002). MRI and novel contrast agents for molecular imaging. In Biomedical Imaging in Experimental Neuroscience. (pp. 293-322).

Modo, M., Sowinski, P., & Hodges, H. (2000). Conditional discrimination learning in rats with global ischaemic brain damage. Behav Brain Res, 111(1-2), 213-221.Elsevier. doi: 10.1016/s0166-4328(00)00160-1.

Modo, M., Stroemer, R.P., Tang, E., Veizovic, T., Sowniski, P., & Hodges, H. (2000). Neurological sequelae and long-term behavioural assessment of rats with transient middle cerebral artery occlusion. J Neurosci Methods, 104(1), 99-109.Elsevier. doi: 10.1016/s0165-0270(00)00329-0.