Michael Lotze

Feist, M., Zhu, Z., Dai, E., Ma, C., Liu, Z., Giehl, E., Ravindranathan, R., Kowalsky, S.J., Obermajer, N., Kammula, U.S., Lee, A.J.H., Lotze, M.T., Guo, Z.S., & Bartlett, D.L. (2021). Oncolytic virus promotes tumor-reactive infiltrating lymphocytes for adoptive cell therapy. CANCER GENE THERAPY, 28(1-2), 98-111.Springer Science and Business Media LLC. doi: 10.1038/s41417-020-0189-4.

Ascierto, P.A., Fox, B.A., Urba, W.J., Anderson, A.C., Atkins, M.B., Borden, E.C., Brahmer, J.R., Butterfield, L.H., Cesano, A., Chen, D.S., de Gruijl, T.D., Dillman, R.O., Drake, C.G., Emens, L.A., Gajewski, T.F., Gulley, J.L., Jr, H.F.S., Hwu, P., Kaufman, D., Kaufman, H.L., Lotze, M.T., McNeel, D.G., Margolin, K.A., Marincola, F.M., Mastrangelo, M.J., Maus, M.V., Parkinson, D.R., Romero, P.J., Sondel, P.M., Spranger, S., Sznol, M., Weiner, G.J., Wigginton, J.M., & Weber, J.S. (2020). Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 8(2), e000878.BMJ. doi: 10.1136/jitc-2020-000878.

Brufsky, A., & Lotze, M.T. (2020). DC/L-SIGNs of hope in the COVID-19 pandemic. JOURNAL OF MEDICAL VIROLOGY, 92(9), 1396-1398.Wiley. doi: 10.1002/jmv.25980.

Brufsky, A., & Lotze, M.T. (2020). Ratcheting down the virulence of SARS-CoV-2 in the COVID-19 pandemic. JOURNAL OF MEDICAL VIROLOGY, 92(11), 2379-2380.Wiley. doi: 10.1002/jmv.26067.

Galluzzi, L., Vitale, I., Warren, S., Adjemian, S., Agostinis, P., Buque Martinez, A., Chan, T.A., Coukos, G., Demaria, S., Deutsch, E., Draganov, D., Edelson, R.L., Formenti, S.C., Fucikova, J., Gabriele, L., Gaipl, U.S., Gameiro, S.R., Garg, A.D., Golden, E., Han, J., Harrington, K.J., Hemminki, A., Hodge, J.W., Hossain, D.M.S., Illidge, T., Karin, M., Kaufman, H.L., Kepp, O., Kroemer, G., Lasarte, J.J., Loi, S., Lotze, M.T., Manic, G., Merghoub, T., Melcher, A.A., Mossman, K.L., Prosper, F., Rekdal, O., Rescigno, M., Riganti, C., Sistigu, A., Smyth, M.J., Spisek, R., Stagg, J., Strauss, B.E., Tang, D., Tatsuno, K., van Gool, S.W., Vandenabeele, P., Yamazaki, T., Zamarin, D., Zitvogel, L., Cesano, A., & Marincola, F.M. (2020). Consensus guidelines for the definition, detection and interpretation of immunogenic cell death. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 8(1), e000337.BMJ. doi: 10.1136/jitc-2019-000337.

Han, J., & Lotze, M.T. (2020). The Adaptome as Biomarker for Assessing Cancer Immunity and Immunotherapy. Methods Mol Biol, 2055, 369-397.Springer New York. doi: 10.1007/978-1-4939-9773-2_17.

Kang, R., Zeh, H., Lotze, M., & Tang, D. (2020). The Multifaceted Effects of Autophagy on the Tumor Microenvironment. TUMOR MICROENVIRONMENT: RECENT ADVANCES, 1225, 95-110.Springer International Publishing. doi: 10.1007/978-3-030-35727-6_7.

Ludwig, N., & Lotze, M.T. (2020). A treatise on endothelial biology and exosomes: homage to Theresa Maria Listowska Whiteside. HNO, 68(2), 71-79.Springer Science and Business Media LLC. doi: 10.1007/s00106-019-00803-1.

Murthy, P., Zenati, M.S., Al Abbas, A.I., Rieser, C.J., Bahary, N., Lotze, M.T., III, Z.H.J., Zureikat, A.H., & Boone, B.A. (2020). Prognostic Value of the Systemic Immune-Inflammation Index (SII) After Neoadjuvant Therapy for Patients with Resected Pancreatic Cancer. ANNALS OF SURGICAL ONCOLOGY, 27(3), 898-906.Springer Science and Business Media LLC. doi: 10.1245/s10434-019-08094-0.

Zamame Ramirez, J.A., Romagnoli, G.G., Falasco, B.F., Gorgulho, C.M., Fogolin, C.S., dos Santos, D.C., Araujo Junior, J.P., Lotze, M.T., Ureshino, R.P., & Kaneno, R. (2020). Blocking drug-induced autophagy with chloroquine in HCT-116 colon cancer cells enhances DC maturation and T cell responses induced by tumor cell lysate. INTERNATIONAL IMMUNOPHARMACOLOGY, 84, 106495.Elsevier BV. doi: 10.1016/j.intimp.2020.106495.

Zeh, H.J., Bahary, N., Boone, B.A., Singhi, A.D., Miller-Ocuin, J.L., Normolle, D.P., Zureikat, A.H., Hogg, M.E., Bartlett, D.L., Lee, K.K., Tsung, A., Marsh, J.W., Murthy, P., Tang, D., Seiser, N., Amaravadi, R.K., Espina, V., Liotta, L., & Lotze, M.T. (2020). A Randomized Phase II Preoperative Study of Autophagy Inhibition with High-Dose Hydroxychloroquine and Gemcitabine/Nab-Paclitaxel in Pancreatic Cancer Patients. CLINICAL CANCER RESEARCH, 26(13), 3126-3134.American Association for Cancer Research (AACR). doi: 10.1158/1078-0432.CCR-19-4042.

Bedognetti, D., Ceccarelli, M., Galluzzi, L., Lu, R., Palucka, K., Samayoa, J., Spranger, S., Warren, S., Wong, K.K., Ziv, E., Chowell, D., Coussens, L.M., De Carvalho, D.D., DeNardo, D.G., Galon, J., Kaufman, H.L., Kirchhoff, T., Lotze, M.T., Luke, J.J., Minn, A.J., Politi, K., Shultz, L.D., Simon, R., Thorsson, V., Weidhaas, J.B., Ascierto, M.L., Ascierto, P.A., Barnes, J.M., Barsan, V., Bommareddy, P.K., Bot, A., Church, S.E., Ciliberto, G., De Maria, A., Draganov, D., Ho, W.S., McGee, H.M., Monette, A., Murphy, J.F., Nistico, P., Park, W., Patel, M., Quigley, M., Radvanyi, L., Raftopoulos, H., Rudqvist, N.P., Snyder, A., Sweis, R.F., Valpione, S., Butterfield, L.H., Disis, M.L., Fox, B.A., Cesano, A., Marincola, F.M., & Canc, S.I.C.S.I.T.C. (2019). Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 7(1), 131.BMJ. doi: 10.1186/s40425-019-0602-4.

Bedognetti, D., Ceccarelli, M., Galluzzi, L., Lu, R., Palucka, K., Samayoa, J., Spranger, S., Warren, S., Wong, K.K., Ziv, E., Chowell, D., Coussens, L.M., De Carvalho, D.D., DeNardo, D.G., Galon, J., Kaufman, H.L., Kirchhoff, T., Lotze, M.T., Luke, J.J., Minn, A.J., Politi, K., Shultz, L.D., Simon, R., Thorsson, V., Weidhaas, J.B., Ascierto, M.L., Ascierto, P.A., Barnes, J.M., Barsan, V., Bommareddy, P.K., Bot, A., Church, S.E., Ciliberto, G., De Maria, A., Draganov, D., Ho, W.S., McGee, H.M., Monette, A., Murphy, J.F., Nistico, P., Park, W., Patel, M., Quigley, M., Radvanyi, L., Raftopoulos, H., Rudqvist, N.P., Snyder, A., Sweis, R.F., Valpione, S., Zappasodi, R., Butterfield, L.H., Disis, M.L., Fox, B.A., Cesano, A., Marincola, F.M., Grp, S.I.C.S.I.T.C., & Task, C.I.R. (2019). Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop (vol 7, 131, 2020). JOURNAL FOR IMMUNOTHERAPY OF CANCER, 7(1), 167.BMJ. doi: 10.1186/s40425-019-0640-y.

Boone, B.A., Murthy, P., Miller-Ocuin, J.L., Liang, X., Russell, K.L., Loughran, P., Gawaz, M., Lotze, M.T., III, Z.H.J., & Vogel, S. (2019). The platelet NLRP3 inflammasome is upregulated in a murine model of pancreatic cancer and promotes platelet aggregation and tumor growth. ANNALS OF HEMATOLOGY, 98(7), 1603-1610.Springer Science and Business Media LLC. doi: 10.1007/s00277-019-03692-0.

Dafni, U., Michielin, O., Lluesma, S.M., Tsourti, Z., Polydoropoulou, V., Karlis, D., Besser, M.J., Haanen, J., Svane, I.M., Ohashi, P.S., Kammula, U.S., Orcurto, A., Zimmermann, S., Trueb, L., Klebanoff, C.A., Lotze, M.T., Kandalaft, L.E., & Coukos, G. (2019). Efficacy of adoptive therapy with tumor-infiltrating lymphocytes and recombinant interleukin-2 in advanced cutaneous melanoma: a systematic review and meta-analysis. ANNALS OF ONCOLOGY, 30(12), 1902-1913.Elsevier BV. doi: 10.1093/annonc/mdz398.

Gorgulho, C.M., Romagnoli, G.G., Bharthi, R., & Lotze, M.T. (2019). Johnny on the Spot-Chronic Inflammation Is Driven by HMGB1. FRONTIERS IN IMMUNOLOGY, 10(JULY), 1561.Frontiers Media SA. doi: 10.3389/fimmu.2019.01561.

Li, G., Sachdev, U., Peters, K., Liang, X., & Lotze, M.T. (2019). The VE-PTP Inhibitor AKB-9778 Improves Antitumor Activity and Diminishes the Toxicity of Interleukin 2 (IL-2) Administration. JOURNAL OF IMMUNOTHERAPY, 42(7), 237-243.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/CJI.0000000000000290.

Murthy, P., Ekeke, C.N., Russell, K.L., Butler, S.C., Wang, Y., Luketich, J.D., Soloff, A.C., Dhupar, R., & Lotze, M.T. (2019). Making cold malignant pleural effusions hot: driving novel immunotherapies. ONCOIMMUNOLOGY, 8(4), e1554969.Informa UK Limited. doi: 10.1080/2162402X.2018.1554969.

Soloff, A.C., & Lotze, M.T. (2019). A peaceful death orchestrates immune balance in a chaotic environment. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116(46), 22901-22903.Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.1916211116.

Tandon, M., Coudriet, G.M., Criscimanna, A., Socorro, M., Eliliwi, M., Singhi, A.D., Cruz-Monserrate, Z., Bailey, P., Lotze, M.T., Zeh, H., Hu, J., Goffin, V., Gittes, G.K., Biankin, A.V., & Esni, F. (2019). Prolactin Promotes Fibrosis and Pancreatic Cancer Progression. CANCER RESEARCH, 79(20), 5316-5327.American Association for Cancer Research (AACR). doi: 10.1158/0008-5472.CAN-18-3064.

Yang, M., Chen, P., Liu, J., Zhu, S., Kroemer, G., Klionsky, D.J., Lotze, M.T., Zeh, H.J., Kang, R., & Tang, D. (2019). Clockophagy is a novel selective autophagy process favoring ferroptosis. SCIENCE ADVANCES, 5(7), eaaw2238.American Association for the Advancement of Science (AAAS). doi: 10.1126/sciadv.aaw2238.

Anunobi, R., Boone, B.A., Cheh, N., Tang, D., Kang, R., Loux, T., Lotze, M.T., & Zeh, H.J. (2018). Extracellular DNA promotes colorectal tumor cell survival after cytotoxic chemotherapy. JOURNAL OF SURGICAL RESEARCH, 226, 181-191.Elsevier BV. doi: 10.1016/j.jss.2018.02.042.

Boone, B.A., Murthy, P., Miller-Ocuin, J., Doerfler, W.R., Ellis, J.T., Liang, X., Ross, M.A., Wallace, C.T., Sperry, J.L., Lotze, M.T., Neal, M.D., & III, Z.H.J. (2018). Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular traps. BMC CANCER, 18(1), 678.Springer Science and Business Media LLC. doi: 10.1186/s12885-018-4584-2.

Chang, P.L. (2018). Somatic Gene Therapy. In Somatic Gene Therapy. (pp. 263-286).CRC Press. doi: 10.1201/9781351076760.

Chen, R., Zhu, S., Fan, X.G., Wang, H., Lotze, M.T., Zeh, H.J., Billiar, T.R., Kang, R., & Tang, D. (2018). High mobility group protein B1 controls liver cancer initiation through yes-associated protein -dependent aerobic glycolysis. HEPATOLOGY, 67(5), 1823-1841.Ovid Technologies (Wolters Kluwer Health). doi: 10.1002/hep.29663.

Kim, H.Y., Wang, X., Kang, R., Tang, D., Boone, B.A., III, Z.H.J., Lotze, M.T., & Edwards, W.B. (2018). RAGE-specific single chain Fv for PET imaging of pancreatic cancer. PLOS ONE, 13(3), e0192821.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0192821.

Song, X., Zhu, S., Xie, Y., Liu, J., Sun, L., Zeng, D., Wang, P., Ma, X., Kroemer, G., Bartlett, D.L., Billiar, T.R., Lotze, M.T., Zeh, H.J., Kang, R., & Tang, D. (2018). JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice. GASTROENTEROLOGY, 154(5), 1480-1493.Elsevier BV. doi: 10.1053/j.gastro.2017.12.004.

Dhupar, R., Van der Kraak, L., Pennathur, A., Schuchert, M.J., Nason, K.S., Luketich, J.D., & Lotze, M.T. (2017). Targeting Immune Checkpoints in Esophageal Cancer: A High Mutational Load Tumor. ANNALS OF THORACIC SURGERY, 103(4), 1340-1349.Elsevier BV. doi: 10.1016/j.athoracsur.2016.12.011.

Goding, S.R., Yu, S., Bailey, L.M., Lotze, M.T., & Basse, P.H. (2017). Adoptive transfer of natural killer cells promotes the anti-tumor efficacy of T cells. CLINICAL IMMUNOLOGY, 177, 76-86.Elsevier BV. doi: 10.1016/j.clim.2016.06.013.

Kaltenmeier, C.T., Vollmer, L.L., Vernetti, L.A., Caprio, L., Davis, K., Korotchenko, V.N., Day, B.W., Tsang, M., Hulkower, K.I., Lotze, M.T., & Vogt, A. (2017). Tumor Cell-Selective Inhibitor of Mitogen-Activated Protein Kinase Phosphatases Sensitizes Breast Cancer Cells to Lymphokine-Activated Killer Cell Activity. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 361(1), 39-50.American Society for Pharmacology & Experimental Therapeutics (ASPET). doi: 10.1124/jpet.116.239756.

Kang, R., Xie, Y., Zhang, Q., Hou, W., Jiang, Q., Zhu, S., Liu, J., Zeng, D., Wang, H., Bartlett, D.L., Billiar, T.R., III, Z.H.J., Lotze, M.T., & Tang, D. (2017). Intracellular HMGB1 as a novel tumor suppressor of pancreatic cancer. CELL RESEARCH, 27(7), 916-932.Springer Science and Business Media LLC. doi: 10.1038/cr.2017.51.

Murthy, P., Durco, F., Miller-Ocuin, J.L., Takedai, T., Shankar, S., Liang, X., Liu, X., Cui, X., Sachdev, U., Rath, D., Lotze, M.T., III, Z.H.J., Gawaz, M., Weber, A.N., & Vogel, S. (2017). The NLRP3 inflammasome and bruton's tyrosine kinase in platelets co-regulate platelet activation, aggregation, and in vitro thrombus formation. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 483(1), 230-236.Elsevier BV. doi: 10.1016/j.bbrc.2016.12.161.

Sachdev, U., & Lotze, M.T. (2017). Perpetual change: autophagy, the endothelium, and response to vascular injury. JOURNAL OF LEUKOCYTE BIOLOGY, 102(2), 221-235.Oxford University Press (OUP). doi: 10.1189/jlb.3RU1116-484RR.

Snyder, H.M., Ahles, T., Calderwood, S., Carrillo, M.C., Chen, H., Chang, C.C.H., Craft, S., De Jager, P., Driver, J.A., Fillit, H., Knopman, D., Lotze, M., Tierney, M.C., Petanceska, S., Saykin, A., Seshadri, S., Shineman, D., & Ganguli, M. (2017). Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation. Alzheimers Dement, 13(3), 267-273.Wiley. doi: 10.1016/j.jalz.2016.11.002.

Xie, Y., Zhu, S., Song, X., Sun, X., Fan, Y., Liu, J., Zhong, M., Yuan, H., Zhang, L., Billiar, T.R., Lotze, M.T., III, Z.H.J., Kang, R., Kroemer, G., & Tang, D. (2017). The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity. CELL REPORTS, 20(7), 1692-1704.Elsevier BV. doi: 10.1016/j.celrep.2017.07.055.

Xie, Y., Zhu, S., Zhong, M., Yang, M., Sun, X., Liu, J., Kroemer, G., Lotze, M., III, Z.H.J., Kang, R., & Tang, D. (2017). Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma. GASTROENTEROLOGY, 153(5), 1429-+.Elsevier BV. doi: 10.1053/j.gastro.2017.07.036.

Zhu, S., Zhang, Q., Sun, X., III, Z.H.J., Lotze, M.T., Kang, R., & Tang, D. (2017). HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells. CANCER RESEARCH, 77(8), 2064-2077.American Association for Cancer Research (AACR). doi: 10.1158/0008-5472.CAN-16-1979.

Chen, R., Xie, Y., Zhong, X., Fu, Y., Huang, Y., Zhen, Y., Pan, P., Wang, H., Bartlett, D.L., Billiar, T.R., Lotze, M.T., III, Z.H.J., Fan, X.G., Tang, D., & Kang, R. (2016). Novel chemokine-like activities of histones in tumor metastasis. ONCOTARGET, 7(38), 61728-61740.Impact Journals, LLC. doi: 10.18632/oncotarget.11226.

Hou, W., Xie, Y., Song, X., Sun, X., Lotze, M.T., Zeh, H.J., Kang, R., & Tang, D. (2016). Autophagy promotes ferroptosis by degradation of ferritin. AUTOPHAGY, 12(8), 1425-1428.Informa UK Limited. doi: 10.1080/15548627.2016.1187366.

Kang, R., Chen, R., Xie, M., Cao, L., Lotze, M.T., Tang, D., & III, Z.H.J. (2016). The Receptor for Advanced Glycation End Products Activates the AIM2 Inflammasome in Acute Pancreatitis. JOURNAL OF IMMUNOLOGY, 196(10), 4331-4337.The American Association of Immunologists. doi: 10.4049/jimmunol.1502340.

Klionsky, D.J., Abdelmohsen, K., Abe, A., Abedin, M.J., Abeliovich, H., Arozena, A.A., Adachi, H., Adams, C.M., Adams, P.D., Adeli, K., Adhihetty, P.J., Adler, S.G., Agam, G., Agarwal, R., Aghi, M.K., Agnello, M., Agostinis, P., Aguilar, P.V., Aguirre-Ghiso, J., Airoldi, E.M., Ait-Si-Ali, S., Akematsu, T., Akporiaye, E.T., Al-Rubeai, M., Albaiceta, G.M., Albanese, C., Albani, D., Albert, M.L., Aldudo, J., Alguel, H., Alirezaei, M., Alloza, I., Almasan, A., Almonte-Beceril, M., Alnemri, E.S., Alonso, C., Altan-Bonnet, N., Altieri, D.C., Alvarez, S., Alvarez-Erviti, L., Alves, S., Amadoro, G., Amano, A., Amantini, C., Ambrosio, S., Amelio, I., Amer, A.O., Amessou, M., Amon, A., An, Z., Anania, F.A., Andersen, S.U., Andley, U.P., Andreadi, C.K., Andrieu-Abadie, N., Anel, A., Ann, D.K., Anoopkumar-Dukie, S., Antonioli, M., Aoki, H., Apostolova, N., Aquila, S., Aquilano, K., Araki, K., Arama, E., Aranda, A., Araya, J., Arcaro, A., Arias, E., Arimoto, H., Ariosa, A.R., Armstrong, J.L., Arnould, T., Arsov, I., Asanuma, K., Askanas, V., Asselin, E., Atarashi, R., Atherton, S.S., Atkin, J.D., Attardi, L.D., Auberger, P., Auburger, G., Aurelian, L., Autelli, R., Avagliano, L., Avantaggiati, M.L., Avrahami, L., Awale, S., Azad, N., Bachetti, T., Backer, J.M., Bae, D.H., Bae, J.S., Bae, O.N., Bae, S.H., Baehrecke, E.H., Baek, S.H., Baghdiguian, S., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X.Y., Bailly, Y., Balaji, K.N., Balduini, W., Ballabio, A., Balzan, R., Banerjee, R., Banhegyi, G., Bao, H., Barbeau, B., Barrachina, M.D., Barreiro, E., Bartel, B., Bartolome, A., Bassham, D.C., Bassi, M.T., Jr, B.R.C., Basu, A., Batista, M.T., Batoko, H., Battino, M., Bauckman, K., Baumgarner, B.L., Bayer, K.U., Beale, R., Beaulieu, J.F., Jr, B.G.R., Becker, C., Beckham, J.D., Bedard, P.A., Bednarski, P.J., Begley, T.J., Behl, C., Behrends, C., Behrens, G.M.N., Behrns, K.E., Bejarano, E., Belaid, A., Belleudi, F., Benard, G., Berchem, G., Bergamaschi, D., Bergami, M., Berkhout, B., Berliocchi, L., Bernard, A., Bernard, M., Bernassola, F., Bertolotti, A., Bess, A.S., Besteiro, S., Bettuzzi, S., Bhalla, S., Bhattacharyya, S., Bhutia, S.K., Biagosch, C., Bianchi, M.W., Biard-Piechaczyk, M., Billes, V., Bincoletto, C., Bingol, B., Bird, S.W., Bitoun, M., Bjedov, I., Blackstone, C., Blanc, L., Blanco, G.A., Blomhoff, H.K., Boada-Romero, E., Boeckler, S., Boes, M., Boesze-Battaglia, K., Boise, L.H., Bolino, A., Boman, A., Bonaldo, P., Bordi, M., Bosch, J., Botana, L.M., Botti, J., Bou, G., Bouche, M., Bouchecareilh, M., Boucher, M.J., Boulton, M.E., Bouret, S.G., Boya, P., Boyer-Guittaut, M., Bozhkov, P.V., Brady, N., Braga, V.M.M., Brancolini, C., Braus, G.H., Bravo-San Pedro, J.M., Brennan, L.A., Bresnick, E.H., Brest, P., Bridges, D., Bringer, M.A., Brini, M., Brito, G.C., Brodin, B., Brookes, P.S., Brown, E.J., Brown, K., Broxmeyer, H.E., Bruhat, A., Brum, P.C., Brumell, J.H., Brunetti-Pierri, N., Bryson-Richardson, R.J., Buch, S., Buchan, A.M., Budak, H., Bulavin, D.V., Bultman, S.J., Bultynck, G., Bumbasirevic, V., Burelle, Y., Burke, R.E., Burmeister, M., Buetikofer, P., Caberlotto, L., Cadwell, K., Cahova, M., Cai, D., Cai, J., Cai, Q., Calatayud, S., Camougrand, N., Campanella, M., Campbell, G.R., Campbell, M., Campello, S., Candau, R., Caniggia, I., Cantoni, L., Cao, L., Caplan, A.B., Caraglia, M., Cardinali, C., Cardoso, S.M., Carew, J.S., Carleton, L.A., Carlin, C.R., Carloni, S., Carlsson, S.R., Carmona-Gutierrez, D., Carneiro, L.A.M., Carnevali, O., Carra, S., Carrier, A., Carroll, B., Casas, C., Casas, J., Cassinelli, G., Castets, P., Castro-Obregon, S., Cavallini, G., Ceccherini, I., Cecconi, F., Cederbaum, A.I., Cena, V., Cenci, S., Cerella, C., Cervia, D., Cetrullo, S., Chaachouay, H., Chae, H.J., Chagin, A.S., Chai, C.Y., Chakrabarti, G., Chamilos, G., Chan, E.Y.W., Chan, M.T.V., Chandra, D., Chandra, P., Chang, C.P., Chang, R.C.C., Chang, T.Y., Chatham, J.C., Chatterjee, S., Chauhan, S., Che, Y., Cheetham, M.E., 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Patnaik, A., Appleman, L.J., Tolcher, A.W., Papadopoulos, K.P., Beeram, M., Rasco, D.W., Weiss, G.J., Sachdev, J.C., Chadha, M., Fulk, M., Ejadi, S., Mountz, J.M., Lotze, M.T., Toledo, F.G.S., Chu, E., Jeffers, M., Pena, C., Xia, C., Reif, S., Genvresse, I., & Ramanathan, R.K. (2016). First-in-human phase I study of copanlisib (BAY 80-6946), an intravenous pan-class I phosphatidylinositol 3-kinase inhibitor, in patients with advanced solid tumors and non-Hodgkin's lymphomas. ANNALS OF ONCOLOGY, 27(10), 1928-1940.Elsevier BV. doi: 10.1093/annonc/mdw282.

Rao, A., Zhang, X., Deibert, C., Sette, P., Grandi, P., & Amankulor, N. (2016). IDH Mutant Gliomas Escape Natural Killer Cell Immune Surveillance by Downregulation of NKG2D Ligand Expression. JOURNAL OF IMMUNOLOGY, 196(10), 1402-1412.Oxford University Press (OUP). doi: 10.1093/neuonc/now061.

Van der Kraak, L., Goel, G., Ramanan, K., Kaltenmeier, C., Zhang, L., Normolle, D.P., Freeman, G.J., Tang, D., Nason, K.S., Davison, J.M., Luketich, J.D., Dhupar, R., & Lotze, M.T. (2016). 5-Fluorouracil upregulates cell surface B7-H1 (PD-L1) expression in gastrointestinal cancers. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 4(1), 65.BMJ. doi: 10.1186/s40425-016-0163-8.

Vogel, S., Rath, D., Borst, O., Mack, A., Loughran, P., Lotze, M.T., Neal, M.D., Billiar, T.R., & Gawaz, M. (2016). Platelet-derived high-mobility group box 1 promotes recruitment and suppresses apoptosis of monocytes. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 478(1), 143-148.Elsevier BV. doi: 10.1016/j.bbrc.2016.07.078.

Xie, Y., Song, X., Sun, X., Huang, J., Zhong, M., Lotze, M.T., III, Z.H.J., Kang, R., & Tang, D. (2016). Identification of baicalein as a ferroptosis inhibitor by natural product library screening. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 473(4), 775-780.Elsevier BV. doi: 10.1016/j.bbrc.2016.03.052.

Yoo, J.Y., Jaime-Ramirez, A.C., Bolyard, C., Dai, H., Nallanagulagari, T., Wojton, J., Hurwitz, B.S., Relation, T., Lee, T.J., Lotze, M.T., Yu, J.G., Zhang, J., Croce, C.M., Yu, J., Caligiuri, M.A., Old, M., & Kaur, B. (2016). Bortezomib Treatment Sensitizes Oncolytic HSV-1-Treated Tumors to NK Cell Immunotherapy. CLINICAL CANCER RESEARCH, 22(21), 5265-5276.American Association for Cancer Research (AACR). doi: 10.1158/1078-0432.CCR-16-1003.

Apetoh, L., Smyth, M.J., Drake, C.G., Abastado, J.P., Apte, R.N., Ayyoub, M., Blay, J.Y., Bonneville, M., Butterfield, L.H., Caignard, A., Castelli, C., Cavallo, F., Celis, E., Chen, L., Colombo, M.P., Comin-Anduix, B., Coukos, G., Dhodapkar, M.V., Dranoff, G., Frazer, I.H., Fridman, W.H., Gabrilovich, D.I., Gilboa, E., Gnjatic, S., Jaeger, D., Kalinski, P., Kaufman, H.L., Kiessling, R., Kirkwood, J., Knuth, A., Liblau, R., Lotze, M.T., Lugli, E., Marincola, F., Melero, I., Melief, C.J., Mempel, T.R., Mittendorf, E.A., Odun, K., Overwijk, W.W., Palucka, A.K., Parmiani, G., Ribas, A., Romero, P., Schreiber, R.D., Schuler, G., Srivastava, P.K., Tartour, E., Valmori, D., van der Burg, S.H., van der Bruggen, P., van den Eynde, B.J., Wang, E., Zou, W., Whiteside, T.L., Speiser, D.E., Pardoll, D.M., Restifo, N.P., & Anderson, A.C. (2015). Consensus nomenclature for CD8⁺ T cell phenotypes in cancer. ONCOIMMUNOLOGY, 4(4), e998538.Informa UK Limited. doi: 10.1080/2162402X.2014.998538.

Boone, B.A., Bahary, N., Zureikat, A.H., Moser, A.J., Normolle, D.P., Wu, W.C., Singhi, A.D., Bao, P., Bartlett, D.L., Liotta, L.A., Espina, V., Loughran, P., Lotze, M.T., & III, Z.H.J. (2015). Safety and Biologic Response of Pre-operative Autophagy Inhibition in Combination with Gemcitabine in Patients with Pancreatic Adenocarcinoma. ANNALS OF SURGICAL ONCOLOGY, 22(13), 4402-4410.Springer Science and Business Media LLC. doi: 10.1245/s10434-015-4566-4.

Boone, B.A., Orlichenko, L., Schapiro, N.E., Loughran, P., Gianfrate, G.C., Ellis, J.T., Singhi, A.D., Kang, R., Tang, D., Lotze, M.T., & Zeh, H.J. (2015). The receptor for advanced glycation end products (RAGE) enhances autophagy and neutrophil extracellular traps in pancreatic cancer. CANCER GENE THERAPY, 22(6), 326-334.Springer Science and Business Media LLC. doi: 10.1038/cgt.2015.21.

Chen, M., Liu, Y., Varley, P., Chang, Y., He, X.X., Huang, H., Tang, D., Lotze, M.T., Lin, J., & Tsung, A. (2015). High-Mobility Group Box 1 Promotes Hepatocellular Carcinoma Progression through miR-21-Mediated Matrix Metalloproteinase Activity. CANCER RESEARCH, 75(8), 1645-1656.American Association for Cancer Research (AACR). doi: 10.1158/0008-5472.CAN-14-2147.

Chen, R., Fu, S., Fan, X.G., Lotze, M.T., III, Z.H.J., Tang, D., & Kang, R. (2015). Nuclear DAMP complex-mediated RAGE-dependent macrophage cell death. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 458(3), 650-655.Elsevier BV. doi: 10.1016/j.bbrc.2015.01.159.

Diniz, B.S., Sibille, E., Ding, Y., Tseng, G., Aizenstein, H.J., Lotrich, F., Becker, J.T., Lopez, O.L., Lotze, M.T., Klunk, W.E., Reynolds, C.F., & Butters, M.A. (2015). Plasma biosignature and brain pathology related to persistent cognitive impairment in late-life depression. MOLECULAR PSYCHIATRY, 20(5), 594-601.Springer Science and Business Media LLC. doi: 10.1038/mp.2014.76.

Ganguli, M., & Lotze, M.T. (2015). Parkinson Disease and Malignant Disease Minding Cancer's Own Business. JAMA ONCOLOGY, 1(5), 641-642.American Medical Association (AMA). doi: 10.1001/jamaoncol.2015.1810.

Huang, J., Xie, Y., Sun, X., III, Z.H.J., Kang, R., Lotze, M.T., & Tang, D. (2015). DAMPs, ageing, and cancer: The 'DAMP Hypothesis'. AGEING RESEARCH REVIEWS, 24(Pt A), 3-16.Elsevier BV. doi: 10.1016/j.arr.2014.10.004.

Liu, Y., Yan, W., Tohme, S., Chen, M., Fu, Y., Tian, D., Lotze, M., Tang, D., & Tsung, A. (2015). Hypoxia induced HMGB1 and mitochondrial DNA interactions mediate tumor growth in hepatocellular carcinoma through Toll-like receptor 9. JOURNAL OF HEPATOLOGY, 63(1), 114-121.Elsevier BV. doi: 10.1016/j.jhep.2015.02.009.

Sehgal, A.R., Konig, H., Johnson, D.E., Tang, D., Amaravadi, R.K., Boyiadzis, M., & Lotze, M.T. (2015). You eat what you are: autophagy inhibition as a therapeutic strategy in leukemia. LEUKEMIA, 29(3), 517-525.Springer Science and Business Media LLC. doi: 10.1038/leu.2014.349.

Shakir, M., Tang, D., Zeh, H.J., Tang, S.W., Anderson, C.J., Bahary, N., & Lotze, M.T. (2015). The Chemokine Receptors CXCR4/CXCR7 and Their Primary Heterodimeric Ligands CXCL12 and CXCL12/High Mobility Group Box 1 in Pancreatic Cancer Growth and Development Finding Flow. PANCREAS, 44(4), 528-534.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/MPA.0000000000000298.

Vogel, S., Bodenstein, R., Chen, Q., Feil, S., Feil, R., Rheinlaender, J., Schaeffer, T.E., Bohn, E., Frick, J.S., Borst, O., Muenzer, P., Walker, B., Markel, J., Csanyi, G., Pagano, P.J., Loughran, P., Jessup, M.E., Watkins, S.C., Bullock, G.C., Sperry, J.L., Zuckerbraun, B.S., Billiar, T.R., Lotze, M.T., Gawaz, M., & Neal, M.D. (2015). Platelet-derived HMGB1 is a critical mediator of thrombosis. JOURNAL OF CLINICAL INVESTIGATION, 125(12), 4638-4654.American Society for Clinical Investigation. doi: 10.1172/JCI81660.

Yu, Y., Xie, Y., Cao, L., Yang, L., Yang, M., Lotze, M.T., Zeh, H.J., Kang, R., & Tang, D. (2015). The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents. Mol Cell Oncol, 2(4), e1054549.Informa UK Limited. doi: 10.1080/23723556.2015.1054549.

Zhu, X., Messer, J.S., Wang, Y., Lin, F., Cham, C.M., Chang, J., Billiar, T.R., Lotze, M.T., Boone, D.L., & Chang, E.B. (2015). Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation. JOURNAL OF CLINICAL INVESTIGATION, 125(3), 1098-1110.American Society for Clinical Investigation. doi: 10.1172/JCI76344.

Bauer, E.M., Zheng, H., Lotze, M.T., & Bauer, P.M. (2014). Recombinant Human Interferon Alpha 2b Prevents and Reverses Experimental Pulmonary Hypertension. In Zhao, Y.Y. (Ed.). PLOS ONE, 9(5), e96720.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0096720.

Boone, B.A., & Lotze, M.T. (2014). Targeting damage-associated molecular pattern molecules (DAMPs) and DAMP receptors in melanoma. Methods Mol Biol, 1102, 537-552.Humana Press. doi: 10.1007/978-1-62703-727-3_29.

Eisenbacher, J.L., Schrezenmeier, H., Jahrsdoerfer, B., Kaltenmeier, C., Rojewski, M.T., Yildiz, T., Beyer, T., Erle, A., Wiegmann, D.S., Grassl, S., Hang, R., Koerper, S., Wiesneth, M., Lotze, M.T., & Lotfi, R. (2014). S100A4 and Uric Acid Promote Mesenchymal Stromal Cell Induction of IL-10⁺/IDO⁺ Lymphocytes. JOURNAL OF IMMUNOLOGY, 192(12), 6102-6110.The American Association of Immunologists. doi: 10.4049/jimmunol.1303144.

Galluzzi, L., Vacchelli, E., Bravo-San Pedro, J.M., Buque, A., Senovilla, L., Baracco, E.E., Bloy, N., Castoldi, F., Abastado, J.P., Agostinis, P., Apte, R.N., Aranda, F., Ayyoub, M., Beckhove, P., Blay, J.Y., Bracci, L., Caignard, A., Castelli, C., Cavallo, F., Celis, E., Cerundolo, V., Clayton, A., Colombo, M.P., Coussens, L., Dhodapkar, M.V., Eggermont, A.M., Fearon, D.T., Fridman, W.H., Fucikova, J., Gabrilovich, D.I., Galon, J., Garg, A., Ghiringhelli, F., Giaccone, G., Gilboa, E., Gnjatic, S., Hoos, A., Hosmalin, A., Jaeger, D., Kalinski, P., Kaerre, K., Kepp, O., Kiessling, R., Kirkwood, J.M., Klein, E., Knuth, A., Lewis, C.E., Liblau, R., Lotze, M.T., Lugli, E., Mach, J.P., Mattei, F., Mavilio, D., Melero, I., Melief, C.J., Mittendorf, E.A., Moretta, L., Odunsi, A., Okada, H., Palucka, A.K., Peter, M.E., Pienta, K.J., Porgador, A., Prendergast, G.C., Rabinovich, G.A., Restifo, N.P., Rizvi, N., Sautes-Fridman, C., Schreiber, H., Seliger, B., Shiku, H., Silva-Santos, B., Smyth, M.J., Speiser, D.E., Spisek, R., Srivastava, P.K., Talmadge, J.E., Tartour, E., Van der Burg, S.H., Van den Eynde, B.J., Vile, R., Wagner, H., Weber, J.S., Whiteside, T.L., Wolchok, J.D., Zitvogel, L., Zou, W., & Kroemer, G. (2014). Classification of current anticancer immunotherapies. ONCOTARGET, 5(24), 12472-12508.Impact Journals, LLC. doi: 10.18632/oncotarget.2998.

Kang, R., Chen, R., Zhang, Q., Hou, W., Wu, S., Cao, L., Huang, J., Yu, Y., Fan, X.G., Yan, Z., Sun, X., Wang, H., Wang, Q., Tsung, A., Billiar, T.R., III, Z.H.J., Lotze, M.T., & Tang, D. (2014). HMGB1 in health and disease. MOLECULAR ASPECTS OF MEDICINE, 40, 1-116.Elsevier BV. doi: 10.1016/j.mam.2014.05.001.

Kang, R., Hou, W., Zhang, Q., Chen, R., Lee, Y.J., Bartlett, D.L., Lotze, M.T., Tang, D., & Zeh, H.J. (2014). RAGE is essential for oncogenic KRAS-mediated hypoxic signaling in pancreatic cancer. CELL DEATH & DISEASE, 5(10), e1480.Springer Science and Business Media LLC. doi: 10.1038/cddis.2014.445.

Kang, R., Lotze, M.T., Zeh, H.J., Billiar, T.R., & Tang, D. (2014). Cell Death and DAMPs in Acute Pancreatitis. MOLECULAR MEDICINE, 20(1), 466-477.Springer Science and Business Media LLC. doi: 10.2119/molmed.2014.00117.

Kang, R., Tang, D., Schapiro, N.E., Loux, T., Livesey, K.M., Billiar, T.R., Wang, H., Van Houten, B., Lotze, M.T., & Zeh, H.J. (2014). The HMGB1/RAGE inflammatory pathway promotes pancreatic tumor growth by regulating mitochondrial bioenergetics. ONCOGENE, 33(5), 567-577.Springer Science and Business Media LLC. doi: 10.1038/onc.2012.631.

Kang, R., Zhang, Q., Hou, W., Yan, Z., Chen, R., Bonaroti, J., Bansal, P., Billiar, T.R., Tsung, A., Wang, Q., Bartlett, D.L., Whitcomb, D.C., Chang, E.B., Zhu, X., Wang, H., Lu, B., Tracey, K.J., Cao, L., Fan, X.G., Lotze, M.T., III, Z.H.J., & Tang, D. (2014). Intracellular Hmgb1 Inhibits Inflammatory Nucleosome Release and Limits Acute Pancreatitis in Mice. GASTROENTEROLOGY, 146(4), 1097-U338.Elsevier BV. doi: 10.1053/j.gastro.2013.12.015.

Kaufmann, S.H.E., Lange, C., Rao, M., Balaji, K.N., Lotze, M., Schito, M., Zumla, A.I., & Maeurer, M. (2014). Progress in tuberculosis vaccine development and host-directed therapies-a state of the art review. LANCET RESPIRATORY MEDICINE, 2(4), 301-320.Elsevier BV. doi: 10.1016/S2213-2600(14)70033-5.

Milutinovic, P.S., Englert, J.M., Crum, L.T., Mason, N.S., Ramsgaard, L., Enghild, J.J., Sparvero, L.J., Lotze, M.T., & Oury, T.D. (2014). Clearance Kinetics and Matrix Binding Partners of the Receptor for Advanced Glycation End Products. PLOS ONE, 9(3), e88259.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0088259.

Tang, D., Kang, R., Van Houten, B., Zeh, H.J., Billiar, T.R., & Lotze, M.T. (2014). High Mobility Group Box 1 (HMGB1) Phenotypic Role Revealed with Stress. MOLECULAR MEDICINE, 20(1), 359-362.Springer Science and Business Media LLC. doi: 10.2119/molmed.2014.00063.

Wang, W., & Lotze, M.T. (2014). Good things come in small packages: exosomes, immunity and cancer. CANCER GENE THERAPY, 21(4), 139-141.Springer Science and Business Media LLC. doi: 10.1038/cgt.2014.14.

Wang, W., Vernon, P., Li, G., Sampath, P., Stephen, T., Liang, X., & Lotze, M. (2014). Depletion of high mobility group box 1(HMGB1) in dendritic cells (DCs) suppresses tumorigenesis and promotes viral clearance. Journal for ImmunoTherapy of Cancer, 2(S3).BMJ. doi: 10.1186/2051-1426-2-s3-p64.

Yang, L., Xie, M., Yang, M., Yu, Y., Zhu, S., Hou, W., Kang, R., Lotze, M.T., Billiar, T.R., Wang, H., Cao, L., & Tang, D. (2014). PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis. NATURE COMMUNICATIONS, 5(1), 4436.Springer Science and Business Media LLC. doi: 10.1038/ncomms5436.

Criscimanna, A., Duan, L.J., Rhodes, J.A., Fendrich, V., Wickline, E., Hartman, D.J., Monga, S.P.S., Lotze, M.T., Gittes, G.K., Fong, G.H., & Esni, F. (2013). PanIN-Specific Regulation of Wnt Signaling by HIF2α during Early Pancreatic Tumorigenesis. CANCER RESEARCH, 73(15), 4781-4790.American Association for Cancer Research (AACR). doi: 10.1158/0008-5472.CAN-13-0566.

Gelfand, E.W., Simon, D., Simon, H.U., Thomas, A., Busse, W.W., Nair, P., Gauvreau, G.M., Denburg, J.A., Bivins-Smith, E.R., Jacoby, D.B., Davis, B.P., Rothenberg, M.E., Khoury, P., Klion, A.D., Lotfi, R., Spada, N., Lotze, M.T., Schleimer, R.P., Kato, A., Kern, R., Lavigne, M.C., Eppihimer, M.J., Roufosse, F., Massart, A., Benghiat, F.S., Lemaitre, P., Le Moine, A., Krahn, M., Bartoli, M., & Levy, N. (2013). Eosinophils in Human Disease. In Eosinophils in Health and Disease. (pp. 431-536).Elsevier. doi: 10.1016/b978-0-12-394385-9.00013-4.

Hou, W., Zhang, Q., Yan, Z., Chen, R., III, Z.H.J., Kang, R., Lotze, M.T., & Tang, D. (2013). Strange attractors: DAMPs and autophagy link tumor cell death and immunity. CELL DEATH & DISEASE, 4(12), e966.Springer Science and Business Media LLC. doi: 10.1038/cddis.2013.493.

Kang, R., Tang, D., Lotze, M.T., & III, Z.H.J. (2013). Autophagy is required for IL-2-mediated fibroblast growth. EXPERIMENTAL CELL RESEARCH, 319(4), 556-565.Elsevier BV. doi: 10.1016/j.yexcr.2012.11.012.

Kang, R., Zhang, Q., III, Z.H.J., Lotze, M.T., & Tang, D. (2013). HMGB1 in Cancer: Good, Bad, or Both?. CLINICAL CANCER RESEARCH, 19(15), 4046-4057.American Association for Cancer Research (AACR). doi: 10.1158/1078-0432.CCR-13-0495.

Kaufman, H.L., Kirkwood, J.M., Hodi, F.S., Agarwala, S., Amatruda, T., Bines, S.D., Clark, J.I., Curti, B., Ernstoff, M.S., Gajewski, T., Gonzalez, R., Hyde, L.J., Lawson, D., Lotze, M., Lutzky, J., Margolin, K., McDermott, D.F., Morton, D., Pavlick, A., Richards, J.M., Sharfman, W., Sondak, V.K., Sosman, J., Steel, S., Tarhini, A., Thompson, J.A., Titze, J., Urba, W., White, R., & Atkins, M.B. (2013). The Society for Immunotherapy of Cancer consensus statement on tumour immunotherapy for the treatment of cutaneous melanoma. NATURE REVIEWS CLINICAL ONCOLOGY, 10(10), 588-598.Springer Science and Business Media LLC. doi: 10.1038/nrclinonc.2013.153.

Kim, S., Kim, S.Y., Pribis, J.P., Lotze, M., Mollen, K.P., Shapiro, R., Loughran, P., Scott, M.J., & Billiar, T.R. (2013). Signaling of High Mobility Group Box 1 (HMGB1) through Toll-like Receptor 4 in Macrophages Requires CD14. MOLECULAR MEDICINE, 19(1), 88-98.Springer Science and Business Media LLC. doi: 10.2119/molmed.2012.00306.

Li, G., Liang, X., & Lotze, M.T. (2013). HMGB1: the central cytokine for all lymphoid cells. FRONTIERS IN IMMUNOLOGY, 4(MAR), 68.Frontiers Media SA. doi: 10.3389/fimmu.2013.00068.

Li, G., Tang, D., & Lotze, M.T. (2013). Menage a Trois in stress: DAMPs, redox and autophagy. SEMINARS IN CANCER BIOLOGY, 23(5), 380-390.Elsevier BV. doi: 10.1016/j.semcancer.2013.08.002.

Lotze, M.T., Maranchie, J., & Appleman, L. (2013). Inhibiting Autophagy A Novel Approach for the Treatment of Renal Cell Carcinoma. CANCER JOURNAL, 19(4), 341-347.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/PPO.0b013e31829da0d6.

Lotze, M.T., Robinson, B.W.S., June, C.H., & Whiteside, T.L. (2013). Tumor immunotherapy. In Clinical Immunology. (pp. 935-945).Elsevier. doi: 10.1016/b978-0-7234-3691-1.00091-x.

Lu, Y., Zhang, Z., Yan, Z., Chen, L., Deng, W., Lotze, M., Wang, Z., Lin, X., & Li, L.Y. (2013). Recombinant GnRH-p53 protein sensitizes breast cancer cells to 5-fluorouracil-induced apoptosis in vitro and in vivo. APOPTOSIS, 18(10), 1214-1223.Springer Science and Business Media LLC. doi: 10.1007/s10495-013-0863-1.

Rubartelli, A., Lotze, M.T., Latz, E., & Manfredi, A. (2013). Mechanisms of sterile inflammation. FRONTIERS IN IMMUNOLOGY, 4(NOV), 398.Frontiers Media SA. doi: 10.3389/fimmu.2013.00398.

Tang, D., & Lotze, M.T. (2013). Autophagy and the Tumor Microenvironment. In Autophagy and Cancer. (pp. 167-189).Springer New York. doi: 10.1007/978-1-4614-6561-4_9.

Tang, S., Bonaroti, J., Unlu, S., Liang, X., Tang, D., Zeh, H.J., & Lotze, M.T. (2013). Sweating the Small Stuff MicroRNAs and Genetic Changes Define Pancreatic Cancer. PANCREAS, 42(5), 740-759.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/MPA.0b013e3182854ab0.

Vernon, P.J., III, Z.H.J., & Lotze, M.T. (2013). The myeloid response to pancreatic carcinogenesis is regulated by the receptor for advanced glycation end-products. ONCOIMMUNOLOGY, 2(5), e24184.Informa UK Limited. doi: 10.4161/onci.24184.

Vernon, P.J., Loux, T.J., Schapiro, N.E., Kang, R., Muthuswamy, R., Kalinski, P., Tang, D., Lotze, M.T., & III, Z.H.J. (2013). The Receptor for Advanced Glycation End Products Promotes Pancreatic Carcinogenesis and Accumulation of Myeloid-Derived Suppressor Cells. JOURNAL OF IMMUNOLOGY, 190(3), 1372-1379.The American Association of Immunologists. doi: 10.4049/jimmunol.1201151.

Whiteside, T.L., Robinson, B.W.S., June, C.H., & Lotze, M.T. (2013). Principles of tumor immunology. In Clinical Immunology. (pp. 925-934).Elsevier. doi: 10.1016/b978-0-7234-3691-1.00090-8.

Zhang, Q., Kang, R., III, Z.H.J., Lotze, M.T., & Tang, D. (2013). DAMPs and autophagy Cellular adaptation to injury and unscheduled cell death. AUTOPHAGY, 9(4), 451-458.Informa UK Limited. doi: 10.4161/auto.23691.

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Pan, P., Cardinal, J., Dhupar, R., Rosengart, M.R., Lotze, M.T., Geller, D.A., Billiar, T.R., & Tsung, A. (2009). Low-dose cisplatin administration in murine cecal ligation and puncture prevents the systemic release of HMGB1 and attenuates lethality. JOURNAL OF LEUKOCYTE BIOLOGY, 86(3), 625-632.Oxford University Press (OUP). doi: 10.1189/jlb.1108713.

Shurin, M.R., & Lotze, M.T. (2009). Dendritic Cells in Cancer: Emergenceof the Discipline. In Dendritic Cells in Cancer. (pp. 11-30).Springer US. doi: 10.1007/978-0-387-88611-4_2.

Sparvero, L.J., Asafu-Adjei, D., Kang, R., Tang, D., Amin, N., Im, J., Rutledge, R., Lin, B., Amoscato, A.A., Zeh, H.J., & Lotze, M.T. (2009). RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation. JOURNAL OF TRANSLATIONAL MEDICINE, 7(1), 17.Springer Science and Business Media LLC. doi: 10.1186/1479-5876-7-17.

Tahara, H., Sato, M., Thurin, M., Wang, E., Butterfield, L.H., Disis, M.L., Fox, B.A., Lee, P.P., Khleif, S.N., Wigginton, J.M., Ambs, S., Akutsu, Y., Chaussabel, D., Doki, Y., Eremin, O., Fridman, W.H., Hirohashi, Y., Imai, K., Jacobson, J., Jinushi, M., Kanamoto, A., Kashani-Sabet, M., Kato, K., Kawakami, Y., Kirkwood, J.M., Kleen, T.O., Lehmann, P.V., Liotta, L., Lotze, M.T., Maio, M., Malyguine, A., Masucci, G., Matsubara, H., Mayrand-Chung, S., Nakamura, K., Nishikawa, H., Palucka, A.K., Petricoin, E.F., Pos, Z., Ribas, A., Rivoltini, L., Sato, N., Shiku, H., Slingluff, C.L., Streicher, H., Stroncek, D.F., Takeuchi, H., Toyota, M., Wada, H., Wu, X., Wulfkuhle, J., Yaguchi, T., Zeskind, B., Zhao, Y., Zocca, M.B., & Marincola, F.M. (2009). Emerging concepts in biomarker discovery; The US-Japan workshop on immunological molecular markers in oncology. JOURNAL OF TRANSLATIONAL MEDICINE, 7(1), 45.Springer Science and Business Media LLC. doi: 10.1186/1479-5876-7-45.

Tang, D., Kang, R., Xiao, W., Zhang, H., Lotze, M.T., Wang, H., & Xiao, X. (2009). Quercetin Prevents LPS-Induced High-Mobility Group Box 1 Release and Proinflammatory Function. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 41(6), 651-660.American Thoracic Society. doi: 10.1165/rcmb.2008-0119OC.

Toer, M., Lotze, M.T., & Holton, N. (2009). Receptor-mediated signalling in plants: molecular patterns and programmes. JOURNAL OF EXPERIMENTAL BOTANY, 60(13), 3645-3654.Oxford University Press (OUP). doi: 10.1093/jxb/erp233.

Ueda, R., Kohanbash, G., Sasaki, K., Fujita, M., Zhu, X., Kastenhuber, E.R., McDonald, H.A., Potter, D.M., Hamilton, R.L., Lotze, M.T., Khan, S.A., Sobol, R.W., & Okada, H. (2009). Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(26), 10746-10751.Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.0811817106.

Livesey, K.M., Tang, D., Zeh, H.J., & Lotze, M.T. (2008). Not just nuclear proteins: 'Novel' autophagy cancer treatment targets-p53 and HMGB1. CURRENT OPINION IN INVESTIGATIONAL DRUGS, 9(12), 1259-1263.

Llovet, J.M., Di Bisceglie, A.M., Bruix, J., Kramer, B.S., Lencioni, R., Zhu, A.X., Sherman, M., Schwartz, M., Lotze, M., Talwalkar, J., Gores, G.J., & Panel of Experts in HCC-Design Clinical Trials. (2008). Design and endpoints of clinical trials in hepatocellular carcinoma. J Natl Cancer Inst, 100(10), 698-711.Oxford University Press (OUP). doi: 10.1093/jnci/djn134.

Lotfi, R., & Lotze, M.T. (2008). Eosinophils induce DC maturation, regulating immunity. JOURNAL OF LEUKOCYTE BIOLOGY, 83(3), 456-460.Oxford University Press (OUP). doi: 10.1189/jlb.0607366.

Lotze, M.T. (2008). A nexus of science and clinical immunology: The federation of clinical immunology societies and the FOCIS Centers of excellence. CLINICAL IMMUNOLOGY, 127(2), 119-120.Elsevier BV. doi: 10.1016/j.clim.2008.02.010.

Lotze, M.T., Mapara, M.Y., & June, C.H. (2008). Tumor immunology and immunotherapy. In Clinical Immunology. (pp. 1181-1195).Elsevier. doi: 10.1016/b978-0-323-04404-2.10079-x.

Moschos, S.J., Mandic, M., Kirkwood, J.M., Storkus, W.J., & Lotze, M.T. (2008). Focus on FOCIS: interleukin 2 treatment associated autoimmunity. Clin Immunol, 127(2), 123-129.Elsevier BV. doi: 10.1016/j.clim.2008.02.011.

Ostberg, T., Wahamaa, H., Palmblad, K., Ito, N., Stridh, P., Shoshan, M., Lotze, M.T., Harris, H.E., & Andersson, U. (2008). Oxaliplatin retains HMGB1 intranuclearly and ameliorates collagen type II-induced arthritis. ARTHRITIS RESEARCH & THERAPY, 10(1), R1.Springer Science and Business Media LLC. doi: 10.1186/ar2347.

Torti, F.M., Altieri, D., Broach, J., Fan, H., Lotze, M., Manfredi, J., Matrisian, L., Yu, D., Giaccia, A., & Consortium, C.B.T. (2008). Ph.D. Training in Cancer Biology. CANCER RESEARCH, 68(22), 9122-9124.American Association for Cancer Research (AACR). doi: 10.1158/0008-5472.CAN-08-2626.

Vakkila, J., Demarco, R.A., & Lotze, M.T. (2008). Coordinate NF-κB and STAT1 activation promotes development of myeloid type 1 dendritic cells. SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 67(3), 260-269.Wiley. doi: 10.1111/j.1365-3083.2007.02068.x.

Zetterstrom, C.K., Jiang, W., Wahamaa, H., Ostberg, T., Aveberger, A.C., Schierbeck, H., Lotze, M.T., Andersson, U., Pisetsky, D.S., & Harris, H.E. (2008). Pivotal Advance:: Inhibition of HMGB1 nuclear translocation as a mechanism for the anti-rheumatic effects of gold sodium thiomalate. JOURNAL OF LEUKOCYTE BIOLOGY, 83(1), 31-38.Oxford University Press (OUP). doi: 10.1189/jlb.0507323.

Atkins, M.B., Carbone, D., Coukos, G., Dhodapkar, M., Ernstoff, M.S., Finke, J., Gajewski, T.F., Gollob, J., Lotze, M.T., Storkus, W., & Weiner, L.M. (2007). Report on the ISBTC mini-symposium on biologic effects of targeted therapeutics. JOURNAL OF IMMUNOTHERAPY, 30(6), 577-590.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/CJI.0b013e318064e7b2.

Del Vecchio, M., Bajetta, E., Canova, S., Lotze, M.T., Wesa, A., Parmiani, G., & Anichini, A. (2007). Interleukin-12: Biological properties and clinical application. CLINICAL CANCER RESEARCH, 13(16), 4677-4685.American Association for Cancer Research (AACR). doi: 10.1158/1078-0432.CCR-07-0776.

Dong, X.D.E., Ito, N., Lotze, M.T., DeMarco, R.A., Popovic, P., Shand, S.H., Watkins, S., Winikoff, S., Brown, C.K., Bartlett, D.L., & III, Z.H.J. (2007). High mobility group box I (HMGB1) release from tumor cells after treatment: Implications for development of targeted chemoimmunotherapy. JOURNAL OF IMMUNOTHERAPY, 30(6), 596-606.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/CJI.0b013e31804efc76.

Ellerman, J.E., Brown, C.K., de Vera, M., Zeh, H.J., Billiar, T., Rubartelli, A., & Lotze, M.T. (2007). Masquerader: High mobility group box-1 and cancer. CLINICAL CANCER RESEARCH, 13(10), 2836-2848.American Association for Cancer Research (AACR). doi: 10.1158/1078-0432.CCR-06-1953.

Farkas, A.M., Kilgore, T.M., & Lotze, M.T. (2007). Detecting DNA: getting and begetting cancer. Curr Opin Investig Drugs, 8(12), 981-986.

Hikawa, H., Lotze, M.T., & Rosenblum, W.D. (2007). Induction of peripheral tolerance by local delivery of dendritic cell progenitors to cardiac allografts in a murine heterotopic heart transplantation model. Gen Thorac Cardiovasc Surg, 55(8), 307-314.Springer Science and Business Media LLC. doi: 10.1007/s11748-007-0133-7.

Ito, N., DeMarco, R.A., Mailliard, R.B., Han, J., Rabinowich, H., Kalinski, P., Stolz, D.B., III, Z.H.J., & Lotze, M.T. (2007). Cytolytic cells induce HMGB1 release from melanoma cell lines. JOURNAL OF LEUKOCYTE BIOLOGY, 81(1), 75-83.Oxford University Press (OUP). doi: 10.1189/jlb.0306169.

Kavanagh, B., Ko, A., Venook, A., Margolin, K., Zeh, H., Lotze, M., Schillinger, B., Liu, W., Lu, Y., Mitsky, P., Schilling, M., Bercovici, N., Loudovaris, M., Guillermo, R., Lee, S.M., Bender, J., Mills, B., & Fong, L. (2007). Vaccination of metastatic colorectal cancer patients with matured dendritic cells loaded with multiple major histocompatibility complex class I peptides. JOURNAL OF IMMUNOTHERAPY, 30(7), 762-772.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/CJI.0b013e318133451c.

Levy, R.M., Mollen, K.P., Prince, J.M., Kaczorowski, D.J., Vallabhaneni, R., Liu, S., Tracey, K.J., Lotze, M.T., Hackam, D.J., Fink, M.P., Vodovotz, Y., & Billiar, T.R. (2007). Systemic inflammation and remote organ injury following trauma require HMGB1. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 293(4), R1538-R1544.American Physiological Society. doi: 10.1152/ajpregu.00272.2007.

Lotfi, R., Lee, J.J., & Lotze, M.T. (2007). Eosinophilic granulocytes and damage-associated molecular pattern molecules (DAMPs) - Role in the inflammatory response within tumors. JOURNAL OF IMMUNOTHERAPY, 30(1), 16-28.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/01.cji.0000211324.53396.f6.

Lotze, M.T., & Gray, J. (2007). A life in passing: Jonathan Gray. JOURNAL OF TRANSLATIONAL MEDICINE, 5(1), 54.Springer Science and Business Media LLC. doi: 10.1186/1479-5876-5-54.

Lotze, M.T., Deisseroth, A., & Rubartelli, A. (2007). Damage associated molecular pattern molecules. CLINICAL IMMUNOLOGY, 124(1), 1-4.Elsevier BV. doi: 10.1016/j.clim.2007.02.006.

Lotze, M.T., Zeh, H.J., Rubartelli, A., Sparvero, L.J., Amoscato, A.A., Washburn, N.R., DeVera, M.E., Liang, X., Toer, M., & Billiar, T. (2007). The grateful dead:: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity. IMMUNOLOGICAL REVIEWS, 220(1), 60-81.Wiley. doi: 10.1111/j.1600-065X.2007.00579.x.

Rubartelli, A., & Lotze, M.T. (2007). Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox. TRENDS IN IMMUNOLOGY, 28(10), 429-436.Elsevier BV. doi: 10.1016/j.it.2007.08.004.

Tsung, A., Zheng, N., Jeyabalan, G., Izuishi, K., Klune, J.R., Geller, D.A., Lotze, M.T., Lu, L., & Billiar, T.R. (2007). Increasing numbers of hepatic dendritic cells promote HIVIGB1-mediated ischemia-reperfusion injury. JOURNAL OF LEUKOCYTE BIOLOGY, 81(1), 119-128.Oxford University Press (OUP). doi: 10.1189/jlb.0706468.

D'Aiuto, L., De Marco, R., Edward, N., Rizzo, A., Chaillet, J.R., Montecalvo, A., Lotze, M.T., & Gambotto, A. (2006). Evidence of the capability of the CMV enhancer to activate in trans gene expression in mammalian cells. DNA AND CELL BIOLOGY, 25(3), 171-180.Mary Ann Liebert Inc. doi: 10.1089/dna.2006.25.171.

Eto, M., Bennouna, J., Hunter, O.C., Lotze, M.T., & Amoscato, A.A. (2006). Importance of C16 ceramide accumulation during apoptosis in prostate cancer cells. INTERNATIONAL JOURNAL OF UROLOGY, 13(2), 148-156.Wiley. doi: 10.1111/j.1442-2042.2006.01249.x.

Izuishi, K., Tsung, A., Jeyabalan, G., Critchlow, N.D., Tracey, K.J., Demarco, R.A., Lotze, M.T., Fink, M.P., Geller, D.A., & Billiar, T.R. (2006). Cutting edge: High-mobility group box 1 preconditioning protects against liver ischemia-reperfusion injury. JOURNAL OF IMMUNOLOGY, 176(12), 7154-7158.The American Association of Immunologists. doi: 10.4049/jimmunol.176.12.7154.

Lotze, M.T. (2006). Cancer gene therapy - The power of negative thinking. GENE THERAPY, 13(3), 191-193.Springer Science and Business Media LLC. doi: 10.1038/sj.gt.3302633.

Lotze, M.T., & Yu, Y. (2006). Cancer genomics: The unknown unknowns. CURRENT OPINION IN INVESTIGATIONAL DRUGS, 7(6), 497-500.

Montag, D.T., & Lotze, M.T. (2006). Rapid flow cytometric measurement of cytokine-induced phosphorylation pathways [CIPP] in human peripheral blood leukocytes. CLINICAL IMMUNOLOGY, 121(2), 215-226.Elsevier BV. doi: 10.1016/j.clim.2006.06.013.

Montag, D.T., & Lotze, M.T. (2006). Successful simultaneous measurement of cell membrane and cytokine induced phosphorylation pathways [CIPP] in human peripheral blood mononuclear cells. JOURNAL OF IMMUNOLOGICAL METHODS, 313(1-2), 48-60.Elsevier BV. doi: 10.1016/j.jim.2006.03.014.

Popovic, P.J., DeMarco, R., Lotze, M.T., Winikoff, S.E., Bartlett, D.L., Krieg, A.M., Guo, Z.S., Brown, C.K., Tracey, K.J., & III, Z.H.J. (2006). High mobility group B1 protein suppresses the human plasmacytoid dendritic cell response to TLR9 agonists. JOURNAL OF IMMUNOLOGY, 177(12), 8701-8707.The American Association of Immunologists. doi: 10.4049/jimmunol.177.12.8701.

Tao, R., Wang, L.F., Chen, C.H., Wang, S.H., Demarco, R.A., Lotze, M.T., Thai, N.L., Fung, J.J., Lu, L., & Qian, S.G. (2006). Mechanistic insights into achievement of cardiac allograft long-term survival by treatment with immature dendritic cells and sub-dose sirolimus. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 25(3), 310-319.Elsevier BV. doi: 10.1016/j.healun.2005.10.005.

Vakkila, J., Jaffe, R., Michelow, M., & Lotzel, M.T. (2006). Pediatric cancers are infiltrated predominantly by macrophages and contain a paucity of dendritic cells: A major nosologic difference with adult tumors. CLINICAL CANCER RESEARCH, 12(7), 2049-2054.American Association for Cancer Research (AACR). doi: 10.1158/1078-0432.CCR-05-1824.

Wang, Y., Zheng, N., Lu, Z., Wu, W., Wang, L., Nakao, A., Lotze, M.T., Langer, C.E., Fung, J.J., Qian, S., & Lu, L. (2006). In vivo expansion of two distinct dendritic cells in mouse livers and its impact on liver immune regulation. LIVER TRANSPLANTATION, 12(12), 1850-1861.Ovid Technologies (Wolters Kluwer Health). doi: 10.1002/lt.20919.

DeMarco, R.A., Fink, M.P., & Lotze, M.T. (2005). Monocytes promote natural killer cell interferon gamma production in response to the endogenous danger signal HMGB1. MOLECULAR IMMUNOLOGY, 42(4), 433-444.Elsevier BV. doi: 10.1016/j.molimm.2004.07.023.

Fujii, S., Nishimura, M.I., & Lotze, M.T. (2005). Regulatory balance between the immune response of tumor antigen-specific T-cell receptor gene-transduced CD8⁺ T cells and the suppressive effects of tolerogenic dendritic cells. CANCER SCIENCE, 96(12), 897-902.Wiley. doi: 10.1111/j.1349-7006.2005.00124.x.

Guo, Z.S., Naik, A., O'Malley, M.E., Popovic, P., Demarco, R., Hu, Y., Yin, X.Y., Yang, S.T., Zeh, H.J., Moss, B., Lotze, M.T., & Bartlett, D.L. (2005). The enhanced tumor selectivity of an oncolytic vaccinia lacking the host range and antiapoptosis genes SPI-1 and SPI-2. CANCER RESEARCH, 65(21), 9991-9998.American Association for Cancer Research (AACR). doi: 10.1158/0008-5472.CAN-05-1630.

Hauskrecht, M., Pelikan, R., Malehorn, D.E., Bigbee, W.L., Lotze, M.T., Zeh, H.J., Whitcomb, D.C., & Lyons-Weiler, J. (2005). Feature Selection for Classification of SELDI-TOF-MS Proteomic Profiles. Appl Bioinformatics, 4(4), 227-246.Springer Science and Business Media LLC. doi: 10.2165/00822942-200504040-00003.

Kalinski, P., Mailliard, R.B., Giermasz, A., Zeh, H.J., Basse, P., Bartlett, D.L., Kirkwood, J.M., Lotze, M.T., & Herberman, R.B. (2005). Natural killer-dendritic cell cross-talk in cancer immunotherapy. EXPERT OPINION ON BIOLOGICAL THERAPY, 5(10), 1303-1315.Informa UK Limited. doi: 10.1517/14712598.5.10.1303.

Lotze, M., & Thomson, A. (2005). Measuring Immunity: Basic Biology and Clinical ssessment.

Lotze, M., & Thomson, A. (2005). Measuring Immunity. Elsevier. doi: 10.1016/b978-0-12-455900-4.x5260-x.

Lotze, M.T., & Tracey, K.J. (2005). High-mobility group box 1 protein (HMGB): Nuclear weapon in the immune arsenal. NATURE REVIEWS IMMUNOLOGY, 5(4), 331-342.Springer Science and Business Media LLC. doi: 10.1038/nri1594.

Lotze, M.T., Lu, L., & Taylor, D.L. (2005). Imaging Cytometry: High Content Screening for Large-Scale Cell Research. In Measuring Immunity. (pp. 660-665).Elsevier. doi: 10.1016/b978-012455900-4/50320-2.

Lotze, M.T., Wang, E., Marincola, F.M., Hanna, N., Bugelski, P.J., Burns, C.A., Coukos, G., Damle, N., Godfrey, T.E., Howell, W.M., Panelli, M.C., Perricone, M.A., Petricoin, E.F., Sauter, G., Scheibenbogen, C., Shivers, S.C., Taylor, D.L., Weinstein, J.N., & Whiteside, T.L. (2005). Workshop on cancer biometrics: identifying biomarkers and surrogates of cancer in patients: a meeting held at the Masur Auditorium, National Institutes of Health. J Immunother, 28(2), 79-119.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/01.cji.0000154251.20125.2e.

Numasaki, M., Watanabe, M., Suzuki, T., Takahashi, H., Nakamura, A., McAllister, F., Hishinuma, T., Goto, J., Lotze, M.T., Kolls, J.K., & Sasaki, H. (2005). IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. JOURNAL OF IMMUNOLOGY, 175(9), 6177-6189.The American Association of Immunologists. doi: 10.4049/jimmunol.175.9.6177.

Pelikan, R., Lotze, M.T., Lyons-Weiler, J., Malehorn, D., & Hauskrecht, M. (2005). Serum Proteomic Profiling and Analysis. In Measuring Immunity. (pp. 649-659).Elsevier. doi: 10.1016/b978-012455900-4/50319-6.

Takahashi, H., Numasaki, M., Lotze, M.T., & Sasaki, H. (2005). Interleukin-17 enhances bFGF-, HGF- and VEGF-induced growth of vascular endothelial cells. IMMUNOLOGY LETTERS, 98(2), 189-193.Elsevier BV. doi: 10.1016/j.imlet.2004.11.012.

Tsung, A., Hoffman, R.A., Izuishi, K., Critchlow, N.D., Nakao, A., Chan, M.H., Lotze, M.T., Geller, D.A., & Billiar, T.R. (2005). Hepatic ischemia/reperfusion injury involves functional TLR4 signaling in nonparenchymal cells. JOURNAL OF IMMUNOLOGY, 175(11), 7661-7668.The American Association of Immunologists. doi: 10.4049/jimmunol.175.11.7661.

Tsung, A., Sahai, R., Tanaka, H., Nakao, A., Fink, M.P., Lotze, M.T., Yang, H., Li, J.H., Tracey, K.J., Geller, D.A., & Billiar, T.R. (2005). The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. JOURNAL OF EXPERIMENTAL MEDICINE, 201(7), 1135-1143.Rockefeller University Press. doi: 10.1084/jem.20042614.

Vakkila, J., DeMarco, R.A., & Lotze, M.T. (2005). Imaging analysis of STAT1 and NF-kappaB translocation in dendritic cells at the single cell level. Drug Discov Today, Suppl, 19-30.

Vakkila, J., Lotze, M.T., Riga, C., & Jaffe, R. (2005). A basis for distinguishing cultured dendritic cells and macrophages in cytospins and fixed sections. PEDIATRIC AND DEVELOPMENTAL PATHOLOGY, 8(1), 43-51.SAGE Publications. doi: 10.1007/s10024-004-5045-2.

Winikoff, S.E., Zeh, H.J., DeMarco, R., & Lotze, M.T. (2005). Handling and Storage of Cells and Sera: Practical Considerations. In Measuring Immunity. (pp. 233-236).Elsevier. doi: 10.1016/b978-012455900-4/50281-6.

Winikoff, S.E., Zeh, H.J., DeMarco, R., & Lotze, M.T. (2005). Cytolytic Assays. In Measuring Immunity. (pp. 343-349).Elsevier. doi: 10.1016/b978-012455900-4/50291-9.

Zeh, H.J., & Lotze, M.T. (2005). Addicted to death - Invasive cancer and the immune response to unscheduled cell death. JOURNAL OF IMMUNOTHERAPY, 28(1), 1-9.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-200501000-00001.

Zeh, H.J., Winikoff, S., Landsittel, D.P., Gorelik, E., Marrangoni, A.M., Velikokhatnaya, L., Winans, M.T., Lee, K., Moser, A., Bartlett, D., Lotze, M.T., Siegfried, J.M., Whitcomb, D., Papacristou, G., Slivka, A., Bigbee, W.L., & Lokshin, A.E. (2005). Multianalyte profiling of serum cytokines for detection of pancreatic cancer. Cancer Biomark, 1(6), 259-269.IOS Press. doi: 10.3233/cbm-2005-1601.

Agha-Mohammadi, S., O'Malley, M., Etemad, A., Wang, Z., Xiao, X., & Lotze, M.T. (2004). Second-generation tetracycline-regulatable promoter: repositioned tet operator elements optimize transactivator synergy while shorter minimal promoter offers tight basal leakiness. JOURNAL OF GENE MEDICINE, 6(7), 817-828.Wiley. doi: 10.1002/jgm.566.

Lotze, M.T., & Papamichail, M. (2004). A primer on cancer immunology and immunotherapy. CANCER IMMUNOLOGY IMMUNOTHERAPY, 53(3), 135-138.Springer Science and Business Media LLC. doi: 10.1007/s00262-003-0467-7.

Lotze, M.T., & Rees, R.C. (2004). Identifying biomarkers and surrogates of tumors (cancer biometrics): correlation with immunotherapies and immune cells. CANCER IMMUNOLOGY IMMUNOTHERAPY, 53(3), 256-261.Springer Science and Business Media LLC. doi: 10.1007/s00262-003-0487-3.

Numasaki, M., Lotze, M.T., & Sasaki, H. (2004). Interleukin-17 augments tumor necrosis factor-α-induced elaboration of proangiogenic factors from fibroblasts. IMMUNOLOGY LETTERS, 93(1), 39-43.Elsevier BV. doi: 10.1016/j.imlet.2004.01.014.

Vakkila, J., & Lotze, M.T. (2004). Inflammation and necrosis promote tumour growth. Nat Rev Immunol, 4(8), 641-648.Springer Science and Business Media LLC. doi: 10.1038/nri1415.

Vakkila, J., DeMarco, R.A., & Lotze, M.T. (2004). Imaging analysis of STAT1 and NF-κB translocation in dendritic cells at the single cell level. JOURNAL OF IMMUNOLOGICAL METHODS, 294(1-2), 123-134.Elsevier BV. doi: 10.1016/j.jim.2004.09.007.

Yu, J., Lu, Y., Zhu, W., Wang, Y., Chen, X., Yi, C., Luo, D., Lotze, M.T., & Zhou, Q. (2004). [Anti-tumor activities of lung cancer dendritic cell vaccine modified by mutant Ki-ras gene in vitro]. Zhongguo Fei Ai Za Zhi, 7(2), 104-107. doi: 10.3779/j.issn.1009-3419.2004.02.06.

Eto, M., Bennouna, J., Hunter, O.C., Hershberger, P.A., Kanto, T., Johnson, C.S., Lotze, M.T., & Amoscato, A.A. (2003). C16 ceramide accumulates following androgen ablation in LNCaP prostate cancer cells. PROSTATE, 57(1), 66-79.Wiley. doi: 10.1002/pros.10275.

Gao, W.T., Kumar, S., Lotze, M.T., Hanning, C., Robbins, P.D., & Gambotto, A. (2003). Innate immunity mediated by the cytokine IL-1 homologue 4 (IL-1H4/IL-1F7) induces IL-12-dependent adaptive and profound antitumor immunity. JOURNAL OF IMMUNOLOGY, 170(1), 107-113.The American Association of Immunologists. doi: 10.4049/jimmunol.170.1.107.

Hashimoto, W., Tanaka, F., Robbins, P.D., Taniguchi, M., Okamura, H., Lotze, M.T., & Tahara, H. (2003). Natural killer, but not natural killer T, cells play a necessary role in the promotion of an innate antitumor response induced by IL-18. INTERNATIONAL JOURNAL OF CANCER, 103(4), 508-513.Wiley. doi: 10.1002/ijc.10844.

KALINSKI, P., STORKUS, W., THOMSON, A., & LOTZE, M. (2003). Interleukin-12 Family [IL-12, 23, 12RA and 27]. In The Cytokine Handbook. (pp. 383-408).Elsevier. doi: 10.1016/b978-012689663-3/50020-x.

Kitagawa, T., Iwazawa, T., Robbins, P.D., Lotze, M.T., & Tahara, H. (2003). Advantages and limitations of particle-mediated transfection (gene gun) in cancer immuno-gene therapy using IL-10, IL-12 or B7-1 in murine tumor models. JOURNAL OF GENE MEDICINE, 5(11), 958-965.Wiley. doi: 10.1002/jgm.441.

LOTZE, M., & HAMILTON, J. (2003). Macrophage Colony Stimulating Factor [CSF-1]. In The Cytokine Handbook. (pp. 927-958).Elsevier. doi: 10.1016/b978-012689663-3/50044-2.

LOTZE, M., & THOMSON, A. (2003). Preface to the Fourth Edition. xix-xxi.Elsevier. doi: 10.1016/b978-012689663-3/50003-x.

Lotze, M.T. (2003). The critical need for cancer biometrics: quantitative, reproducible measures of cancer to define response to therapy. Curr Opin Investig Drugs, 4(6), 649-651.

Lotze, M.T. (2003). Editorial overview: Dealing with death: HMGB1 as a novel target for cancer therapy. Current Opinion in Investigational Drugs, 4(12), 1405-1409.

Nishioka, Y., Wen, H., Mitani, K., Robbins, P.D., Lotze, M.T., Sone, S., & Tahara, H. (2003). Differential effects of IL-12 on the generation of alloreactive CTL mediated by murine and human dendritic cells: a critical role for nitric oxide. JOURNAL OF LEUKOCYTE BIOLOGY, 73(5), 621-629.Oxford University Press (OUP). doi: 10.1189/jlb.0402205.

Numasaki, M., Fukushi, J., Ono, M., Narula, S.K., Zavodny, P.J., Kudo, T., Robbins, P.D., Tahara, H., & Lotze, M.T. (2003). Interleukin-17 promotes angiogenesis and tumor growth. BLOOD, 101(7), 2620-2627.American Society of Hematology. doi: 10.1182/blood-2002-05-1461.

OKADA, H., BANCHEREAU, J., & LOTZE, M. (2003). Interleukin-4. In The Cytokine Handbook. (pp. 227-262).Elsevier. doi: 10.1016/b978-012689663-3/50014-4.

OKAMURA, H., LOTZE, M., TSUTSUI, H., KASHIWAMURA, S., UEDA, H., YOSHIMOTO, T., & NAKANISHI, K. (2003). Interleukin-18 [IL-1F4]. In The Cytokine Handbook. (pp. 709-733).Elsevier. doi: 10.1016/b978-012689663-3/50033-8.

Redlinger, R.E., Mailliard, R.B., Lotze, M.T., & Barksdale, E.M. (2003). Synergistic interleukin-18 and low-dose interleukin-2 promote regression of established murine neuroblastoma in vivo. JOURNAL OF PEDIATRIC SURGERY, 38(3), 301-307.Elsevier BV. doi: 10.1053/jpsu.2003.50098.

Son, Y.I., Dallal, R.M., & Lotze, M.T. (2003). Combined treatment with interleukin-18 and low-dose interleukin-2 induced regression of a murine sarcoma and memory response. JOURNAL OF IMMUNOTHERAPY, 26(3), 234-240.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-200305000-00007.

Son, Y.I., Dallal, R.M., & Lotze, M.T. (2003). Combined treatment with interleukin-18 and low-dose interleukin-2 induced regression of a murine sarcoma and memory response. Journal of Immunotherapy, 26(3), 4738.

Thomson, A.W., & Lotze, M.T. (2003). The Cytokine Handbook. 1-1396.

Dallal, R.M., Christakos, P., Lee, K., Egawa, S., Son, Y.I., & Lotze, M.T. (2002). Paucity of dendritic cells in pancreatic cancer. SURGERY, 131(2), 135-138.Elsevier BV. doi: 10.1067/msy.2002.119937.

Jonak, Z.L., Trulli, S., Maier, C., McCabe, F.L., Kirkpatrick, R., Johanson, K., Ho, Y.S., Elefante, L., Chen, Y.J., Herzyk, D., Lotze, M.T., & Johnson, R.K. (2002). High-dose recombinant interleukin-18 induces an effective Th1 immune response to murine MOPC-315 plasmacytoma. JOURNAL OF IMMUNOTHERAPY, 25(SUPPL. 1), S20-S27.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-200203001-00004.

Kumar, S., Hanning, C.R., Brigham-Burke, M.R., Rieman, D.J., Lehr, R., Khandekar, S., Kirkpatrick, R.B., Scott, G.F., Lee, J.C., Lynch, F.J., Gao, W.T., Gambotto, A., & Lotze, M.T. (2002). Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-γ production. CYTOKINE, 18(2), 61-71.Elsevier BV. doi: 10.1006/cyto.2002.0873.

Lotze, M.T., & Kost, T.A. (2002). Viruses as gene delivery vectors: Application to gene function, target validation, and assay development. CANCER GENE THERAPY, 9(8), 692-699.Springer Science and Business Media LLC. doi: 10.1038/sj.cgt.7700493.

Lotze, M.T., Tahara, H., & Okamura, H. (2002). Interleukin-18 as a novel, distinct, and distant member of the interleukin-1 family promoting development of the adaptive immune response:: The interleukin-18 issue of the Journal of Immunotherapy. JOURNAL OF IMMUNOTHERAPY, 25(SUPPL. 1), S1-S3.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-200203001-00001.

Mailliard, R.B., Egawa, S., Cai, Q., Kalinska, A., Bykovskaya, S.N., Lotze, M.T., Kapsenberg, M.L., Storkus, W.J., & Kalinski, P. (2002). Complementary dendritic cell-activating function of CD8⁺ and CD4⁺ T cells:: Helper role of CD8⁺ T cells in the development of T helper type 1 responses. JOURNAL OF EXPERIMENTAL MEDICINE, 195(4), 473-483.Rockefeller University Press. doi: 10.1084/jem.20011662.

Odoux, C., Albers, A., Amoscato, A.A., Lotze, M.T., & Wong, M.K.K. (2002). Trail, FASL and a blocking anti-DR5 antibody augment paclitaxel-induced apoptosis in human non-small-cell lung cancer. INTERNATIONAL JOURNAL OF CANCER, 97(4), 458-465.Wiley. doi: 10.1002/ijc.1640.

Satoh, Y., Esche, C., Gambotto, A., Shurin, G.V., Yurkovetsky, Z.R., Robbins, P.D., Watkins, S.C., Todo, S., Herberman, R.B., Lotze, M.T., & Shurin, M.R. (2002). Local administration of IL-12-transfected dendritic cells induces antitumor immune responses to colon adenocarcinoma in the liver in mice. J Exp Ther Oncol, 2(6), 337-349.Wiley. doi: 10.1046/j.1359-4117.2002.01050.x.

Shimamura, H., Cumberland, R., Hiroishi, K., Watkins, S.C., Lotze, M.T., & Baar, J. (2002). Murine dendritic cell-induced tumor apoptosis is partially mediated by nitric oxide. JOURNAL OF IMMUNOTHERAPY, 25(3), 226-234.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-200205000-00005.

Tanaka, F., Hashimoto, W., Robbins, P.D., Lotze, M.T., & Tahara, H. (2002). Therapeutic and specific antitumor immunity induced by co-administration of immature dendritic cells and adenoviral vector expressing biologically active IL-18. GENE THERAPY, 9(21), 1480-1486.Springer Science and Business Media LLC. doi: 10.1038/sj.gt.3301827.

Chi, K.H., Myers, J.N., Chow, K.C., Chan, W.K., Tsang, Y.W., Chao, Y., & Yen, S.H. (2001). Phase II trial of systemic recombinant interleukin-2 in the treatment of refractory nasopharyngeal carcinoma. ONCOLOGY, 60(2), 110-115.S. Karger AG. doi: 10.1159/000055306.

Dallal, R.M., & Lotze, M.T. (2001). Immunotherapy of metastasis. Surg Oncol Clin N Am, 10(2), 433-xi.Elsevier BV. doi: 10.1016/s1055-3207(18)30074-7.

Dworacki, G., Meidenbauer, N., Kuss, I., Hoffmann, T.K., Gooding, W., Lotze, M., & Whiteside, T.L. (2001). Decreased ζ Chain Expression and Apoptosis in CD3⁺ Peripheral Blood T Lymphocytes of Patients with Melanoma. Clinical Cancer Research, 7(3).

Dworacki, G., Meidenbauer, N., Kuss, I., Hoffmann, T.K., Gooding, W., Lotze, M., & Whiteside, T.L. (2001). Decreased ζ Chain Expression and Apoptosis in CD3⁺ Peripheral Blood T Lymphocytes of Patients with Melanoma. Cancer Research, 7.

Dworacki, G., Meidenbauer, N., Kuss, I., Hoffmann, T.K., Gooding, W., Lotze, M., & Whiteside, T.L. (2001). Decreased zeta chain expression and apoptosis in CD3+ peripheral blood T lymphocytes of patients with melanoma. Clin Cancer Res, 7(3 Suppl), 947s-957s.

Finn, O.J., & Lotze, M.T. (2001). A decade in the life of tumor immunology. CLINICAL CANCER RESEARCH, 7(3), 759S-760S.

Finn, O.J., & Lotze, M.T. (2001). A Decade in the Life of Tumor Immunology. Clinical Cancer Research, 7(3).

Finn, O.J., & Lotze, M.T. (2001). A decade in the life of tumor immunology. Clinical Cancer Research, 7(11 SUPPL.).

Flaherty, L.E., Atkins, M., Sosman, J., Weiss, G., Clark, J.I., Margolin, K., Dutcher, J., Gordon, M.S., Lotze, M., Mier, J., Sorokin, P., Fisher, R.I., Appel, C., & Du, W. (2001). Outpatient biochemotherapy with interleukin-2 and interferon alfa-2b in patients with metastatic malignant melanoma: Results of two phase II cytokine working group trials. JOURNAL OF CLINICAL ONCOLOGY, 19(13), 3194-3202.American Society of Clinical Oncology (ASCO). doi: 10.1200/JCO.2001.19.13.3194.

Fujii, S., Shimizu, K., Shimizu, T., & Lotze, M.T. (2001). Interleukin-10 promotes the maintenance of antitumor CD8⁺ T-cell effector function in situ. BLOOD, 98(7), 2143-2151.American Society of Hematology. doi: 10.1182/blood.V98.7.2143.

Iwazawa, T., Chau, G.Y., Mori, T., Dookeran, K.A., Rubin, J.T., Watkins, S., Robbins, P.D., Lotze, M.T., & Tahara, H. (2001). Potent antitumor effects of intra-arterial injection of fibroblasts genetically engineered to express IL-12 in liver metastasis model of rat: No additional benefit of using retroviral producer cell. CANCER GENE THERAPY, 8(1), 17-22.Springer Science and Business Media LLC. doi: 10.1038/sj.cgt.7700272.

Kang, W.K., Park, C., Yoon, H.L., Kim, W.S., Yoon, S.S., Lee, M.H., Park, K., Kim, K., Jeong, H.S., Kim, J.A., Nam, S.J., Yang, J.H., Son, Y.I., Baek, C.H., Han, J.H., Ree, H.J., Lee, E.S., Kim, S.H., Kim, D.W., Ahn, Y.C., Huh, S.J., Choe, Y.H., Lee, J.H., Park, M.H., Kong, G.S., Park, E.Y., Kang, Y.K., Bang, Y.J., Paik, N.S., Lee, S.N., Kim, S.H., Kim, S., Robbins, P.D., Tahara, H., Lotze, M.T., & Park, C.H. (2001). Interleukin 12 gene therapy of cancer by peritumoral injection of transduced autologous fibroblasts: Outcome of a phase I study. HUMAN GENE THERAPY, 12(6), 671-684.Mary Ann Liebert Inc. doi: 10.1089/104303401300057388.

Kanto, T., Kalinski, P., Hunter, O.C., Lotze, M.T., & Amoscato, A.A. (2001). Ceramide mediates tumor-induced dendritic cell apoptosis. JOURNAL OF IMMUNOLOGY, 167(7), 3773-3784.The American Association of Immunologists. doi: 10.4049/jimmunol.167.7.3773.

Mailliard, R.B., & Lotze, M.T. (2001). Dendritic cells prolong tumor-specific T-cell survival and effector function after interaction with tumor targets. Clinical Cancer Research, 7(11 SUPPL.).

Matsko, C.M., Hunter, O.C., Rabinowich, H., Lotze, M.T., & Amoscato, A.A. (2001). Mitochondrial lipid alterations during Fas- and radiation-induced apoptosis. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 287(5), 1112-1120.Elsevier BV. doi: 10.1006/bbrc.2001.5696.

Okada, H., Attanucci, J., Giezeman-Smits, K.M., Brissette-Storkus, C., Fellows, W.K., Gambotto, A., Pollack, I.F., Pogue-Geile, K., Lotze, M.T., Bozik, M.E., & Chambers, W.H. (2001). Immunization with an antigen identified by cytokine tumor vaccine-assisted SEREX (CAS) suppressed growth of the rat 9L glioma in vivo. CANCER RESEARCH, 61(6), 2625-2631.

Okada, H., Villa, L., Attanucci, J., Erff, M., Fellows, W.K., Lotze, M.T., Pollack, I.F., & Chambers, W.H. (2001). Cytokine gene therapy of gliomas: effective induction of therapeutic immunity to intracranial tumors by peripheral immunization with interleukin-4 transduced glioma cells. GENE THERAPY, 8(15), 1157-1166.Springer Science and Business Media LLC. doi: 10.1038/sj.gt.3301496.

Shimizu, T., Berhanu, A., Redlinger, R.E., Watkins, S., Lotze, M.T., & Barksdale, E.M. (2001). Interleukin-12 transduced dendritic cells induce regression of established murine neuroblastoma. JOURNAL OF PEDIATRIC SURGERY, 36(8), 1285-1292.Elsevier BV. doi: 10.1053/jpsu.2001.25796.

Shurin, G.V., Shurin, M.R., Bykovskaia, S., Shogan, J., Lotze, M.T., & Barksdale, E.M. (2001). Neuroblastoma-derived gangliosides inhibit dendritic cell generation and function. CANCER RESEARCH, 61(1), 363-369.

Son, Y.I., Dallal, R.M., Mailliard, R.B., Egawa, S., Jonak, Z.L., & Lotze, M.T. (2001). Interleukin-18 (IL-18) synergizes with IL-2 to enhance cytotoxicity, interferon-γ production, and expansion of natural killer cells. CANCER RESEARCH, 61(3), 884-888.

Son, Y.I., Mailliard, R.B., Watkins, S.C., & Lotze, M.T. (2001). Dendritic cells pulsed with apoptotic squamous cell carcinoma have anti-tumor effects when combined with interleukin-2. LARYNGOSCOPE, 111(8), 1472-1478.Wiley. doi: 10.1097/00005537-200108000-00026.

Agha-Mohammadi, S., & Lotze, M.T. (2000). Regulatable systems: applications in gene therapy and replicating viruses. JOURNAL OF CLINICAL INVESTIGATION, 105(9), 1177-1183.American Society for Clinical Investigation. doi: 10.1172/JCI10027.

Agha-Mohammadi, S., & Lotze, M.T. (2000). Immunomodulation of cancer: potential use of selectively replicating agents. JOURNAL OF CLINICAL INVESTIGATION, 105(9), 1173-1176.American Society for Clinical Investigation. doi: 10.1172/JCI10026.

Dallal, R.M., & Lotze, M.T. (2000). The dendritic cell and human cancer vaccines. CURRENT OPINION IN IMMUNOLOGY, 12(5), 583-588.Elsevier BV. doi: 10.1016/S0952-7915(00)00146-1.

Dutcher, J.P., Logan, T., Gordon, M., Sosman, J., Weiss, G., Margolin, K., Plasse, T., Mier, J., Lotze, M., Clark, J., & Atkins, M. (2000). Phase II trial of interleukin 2, interferon alpha, and 5-fluorouracil in metastatic renal cell cancer: a cytokine working group study. Clin Cancer Res, 6(9), 3442-3450.

Egawa, S., & Lotze, M.T. (2000). The Laheru/Jaffee article reviewed. ONCOLOGY-NEW YORK, 14(2), 259-260.

Esche, C., Cai, Q., Peron, J.M., Hunter, O., Subbotin, V.M., Lotze, M.T., & Shurin, M.R. (2000). Interleukin-12 and Flt3 ligand differentially promote dendropoiesis in vivo. European Journal of Immunology, 30(9), 2565-2575. doi: 10.1002/1521-4141(200009)30:9<2565::AID-IMMU2565>3.0.CO;2-V.

Giezeman-Smits, K.M., Okada, H., Brissette-Storkus, C.S., Villa, L.A., Attanucci, J., Lotze, M.T., Pollack, I.F., Bozik, M.E., & Chambers, W.H. (2000). Cytokine gene therapy of gliomas:: Induction of reactive CD4⁺ T cells by interleukin-4-transfected 9L gliosarcoma is essential for protective immunity. CANCER RESEARCH, 60(9), 2449-2457.

Hirao, M., Onai, N., Hiroishi, K., Watkins, S.C., Matsushima, K., Robbins, P.D., Lotze, M.T., & Tahara, H. (2000). CC chemokine receptor-7 on dendritic cells is induced after interaction with apoptotic tumor cells: Critical role in migration from the tumor site to draining lymph nodes. CANCER RESEARCH, 60(8), 2209-2217.

Hiroishi, K., Tüting, T., & Lotze, M.T. (2000). IFN-α-expressing tumor cells enhance generation and promote survival of tumor-specific CTLs. Journal of Immunology, 164(2), 567-572. doi: 10.4049/jimmunol.164.2.567.

Lotze, M.T. (2000). The future role of interleukin-2 in cancer therapy. CANCER JOURNAL FROM SCIENTIFIC AMERICAN, 6(SUPPL. 1), S58-S60.

Lotze, M.T., Shurin, M., Esche, C., Tahara, H., Storkus, W., Kirkwood, J.M., Whiteside, T.L., Elder, E.M., Okada, H., & Robbins, P. (2000). Interleukin-2: Developing additional cytokine gene therapies using fibroblasts or dendritic cells to enhance tumor immunity. CANCER JOURNAL FROM SCIENTIFIC AMERICAN, 6(SUPPL. 1), S61-S66.

Mailliard, R.B., Dallal, R.M., Son, Y.I., & Lotze, M.T. (2000). Dendritic cells promote T-cell survival or death depending upon their maturation state and presentation of antigen. Immunol Invest, 29(2), 177-185.Informa UK Limited. doi: 10.3109/08820130009062302.

Okada, H., Attanucci, J., Tahara, H., Pollack, I.F., Bozik, M.E., Chambers, W.H., & Lotze, M.T. (2000). Characterization and transduction of a retroviral vector encoding human interleukin-4 and herpes simplex virus-thymidine kinase for glioma tumor vaccine therapy. CANCER GENE THERAPY, 7(3), 486-494.Springer Science and Business Media LLC. doi: 10.1038/sj.cgt.7700140.

Okada, H., Pollack, I.F., Lotze, M.T., Lunsford, L.D., Kondziolka, D., Lieberman, F., Schiff, D., Attanucci, J., Edington, H., Chambers, W., Robbins, P., Baar, J., Kinzler, D., Whiteside, T., & Elder, E. (2000). Gene therapy of malignant gliomas: A phase I study of IL-4-HSV-TK gene-modified autologous tumor to elicit an immune response. HUMAN GENE THERAPY, 11(4), 637-653.Mary Ann Liebert Inc. doi: 10.1089/10430340050015824.

Pirtskhalaishvili, G., Shurin, G.V., Esche, C., Cai, Q., Salup, R.R., Bykovskaia, S.N., Lotze, M.T., & Shurin, M.R. (2000). Cytokine-mediated protection of human dendritic cells from prostate cancer-induced apoptosis is regulated by the Bcl-2 family of proteins. Br J Cancer, 83(4), 506-513.Springer Science and Business Media LLC. doi: 10.1054/bjoc.2000.1289.

Ranieri, E., Kierstead, L.S., Zarour, H., Kirkwood, J.M., Lotze, M.T., Whiteside, T., & Storkus, W.J. (2000). Dendritic cell/peptide cancer vaccines: clinical responsiveness and epitope spreading. Immunol Invest, 29(2), 121-125.Informa UK Limited. doi: 10.3109/08820130009062294.

Rosenberg, S.A., Blaese, R.M., Brenner, M.K., Deisseroth, A.B., Ledley, F.D., Lotze, M.T., Wilson, J.M., Nabel, G.J., Cornetta, K., Economou, J.S., Freeman, S.M., Riddell, S.R., Brenner, M., Oldfield, E., Gansbacher, B., Dunbar, C., Walker, R.E., Schuening, F.G., Roth, J.A., Crystal, R.G., Welsh, M.J., Culver, K., Heslop, H.E., Simons, J., Wilmott, R.W., Boucher, R.C., Siegler, H.F., Barranger, J.A., Karlsson, S., Kohn, D., Galpin, J.E., Raffel, C., Hesdorffer, C., Ilan, J., Cassileth, P., O'Shaughnessy, J., Kun, L.E., Das, T.K., Wong-Staal, F., Sobol, R.E., Haubrich, R., Sznol, M., Rubin, J., Sorcher, E.J., Rosenblatt, J., Walker, R., Brigham, K., Vogelzang, N., Hersh, E., & Eck, S.L. (2000). Human gene marker/therapy clinical protocols. Hum Gene Ther, 11(6), 919-979.Mary Ann Liebert Inc. doi: 10.1089/10430340050015536.

Saito, T., Dworacki, G., Gooding, W., Lotze, M.T., & Whiteside, T.L. (2000). Spontaneous apoptosis of CD8⁺ T lymphocytes in peripheral blood of patients with advanced melanoma. CLINICAL CANCER RESEARCH, 6(4), 1351-1364.

Tanaka, F., Hashimoto, W., Okamura, H., Robbins, P.D., Lotze, M.T., & Tahara, H. (2000). Rapid generation of potent and tumor-specific cytotoxic T lymphocytes by interleukin 18 using dendritic cells and natural killer cells. CANCER RESEARCH, 60(17), 4838-4844.

Watkins, C. (2000). Preface. 21, IV.Elsevier. doi: 10.1016/b978-012455900-4/50261-0.

Weigel, T.L., Lotze, M.T., Kim, P.K., Amoscato, A.A., Luketich, J.D., & Odoux, C. (2000). Paclitaxel-induced apoptosis in non–small cell lung cancer cell lines is associated with increased caspase-3 activity. The Journal of Thoracic and Cardiovascular Surgery, 119(4), 795-803.Elsevier BV. doi: 10.1016/s0022-5223(00)70016-x.

Atkins, M.B., Lotze, M.T., Dutcher, J.P., Fisher, R.I., Weiss, G., Margolin, K., Abrams, J., Sznol, M., Parkinson, D., Hawkins, M., Paradise, C., Kunkel, L., & Rosenberg, S.A. (1999). High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: Analysis of 270 patients treated between 1985 and 1993. JOURNAL OF CLINICAL ONCOLOGY, 17(7), 2105-2116.American Society of Clinical Oncology (ASCO). doi: 10.1200/JCO.1999.17.7.2105.

Chikamatsu, K., Nakano, K., Storkus, W.J., Appella, E., Lotze, M.T., Whiteside, T.L., & DeLeo, A.B. (1999). Generation of anti-p53 cytotoxic T lymphocytes from human peripheral blood using autologous dendritic cells. CLINICAL CANCER RESEARCH, 5(6), 1281-1288.

Esche, C., Gambotto, A., Satoh, Y., Gerein, V., Robbins, P.D., Watkins, S.C., Lotze, M.T., & Shurin, M.R. (1999). CD154 inhibits tumor-induced apoptosis in dendritic cells and tumor growth. EUROPEAN JOURNAL OF IMMUNOLOGY, 29(7), 2148-2155.Wiley. doi: 10.1002/(SICI)1521-4141(199907)29:07<2148::AID-IMMU2148>3.0.CO;2-F.

Esche, C., Lokshin, A., Shurin, G.V., Gastman, B.R., Rabinowich, H., Watkins, S.C., Lotze, M.T., & Shurin, M.R. (1999). Tumor's other immune targets: dendritic cells. JOURNAL OF LEUKOCYTE BIOLOGY, 66(2), 336-344.Oxford University Press (OUP). doi: 10.1002/jlb.66.2.336.

Esche, C., Makarenkova, V.P., Kost, N.V., Lotze, M.T., Zozulya, A.A., & Shurin, M.R. (1999). Murine dendritic cells express functional delta-type opioid receptors. CUTANEOUS NEUROIMMUNOMODULATION: THE PROOPIOMELANOCORTIN SYSTEM, 885(1), 387-390.Wiley. doi: 10.1111/j.1749-6632.1999.tb08695.x.

Esche, C., Shurin, M.R., & Lotze, M.T. (1999). The use of dendritic cells for cancer vaccination. CURRENT OPINION IN MOLECULAR THERAPEUTICS, 1(1), 72-81.

Esche, C., Shurin, M.R., & Lotze, M.T. (1999). Gene therapy for melanoma. Dermatologic Therapy, 10, 74-82.

Esche, C., Subbotin, V.M., Hunter, O., Peron, J.M., Maliszewski, C., Lotze, M.T., & Shurin, M.R. (1999). Differential regulation of epidermal and dermal dendritic cells by IL-12 and Flt3 ligand. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 113(6), 1028-1032.Elsevier BV. doi: 10.1046/j.1523-1747.1999.00779.x.

Gambotto, A., Tüting, T., McVey, D.L., Kovesdi, I., Tahara, H., Lotze, M.T., & Robbins, P.D. (1999). Induction of antitumor immunity by direct intratumoral injection of a recombinant adenovirus vector expressing interleukin-12. CANCER GENE THERAPY, 6(1), 45-53.Springer Science and Business Media LLC. doi: 10.1038/sj.cgt.7700013.

Hashimoto, W., Osaki, T., Okamura, H., Robbins, P.D., Kurimoto, M., Nagata, S., Lotze, M.T., & Tahara, H. (1999). Differential antitumor effects of administration of recombinant IL-18 or recombinant IL-12 are mediated primarily by Fas-Fas ligand- and perforin-induced tumor apoptosis, respectively. JOURNAL OF IMMUNOLOGY, 163(2), 583-589.

Hiroishi, K., Tüting, T., Tahara, H., & Lotze, M.T. (1999). Interferon-alpha gene therapy in combination with CD80 transduction reduces tumorigenicity and growth of established tumor in poorly immunogenic tumor models. GENE THERAPY, 6(12), 1988-1994.Springer Science and Business Media LLC. doi: 10.1038/sj.gt.3301034.

Lotze, M.T. (1999). In vivo veritas. CLINICAL IMMUNOLOGY, 93(1), 1-4.Elsevier BV. doi: 10.1006/clim.1999.4786.

Lotze, M.T. (1999). Not just an antigen-presenting cell: 5th International Symposium on Dendritic Cells in Fundamental and Clinical Immunology. JOURNAL OF LEUKOCYTE BIOLOGY, 66(2), 195-200.Oxford University Press (OUP). doi: 10.1002/jlb.66.2.195.

McMasters, K.M., Sondak, V.K., Lotze, M.T., & Ross, M.I. (1999). Recent advances in melanoma staging and therapy. ANNALS OF SURGICAL ONCOLOGY, 6(5), 467-475.Springer Science and Business Media LLC. doi: 10.1007/s10434-999-0467-8.

Muller, A., Buhn, K., Baraki, H., Lotze, M., & Becker, H. (1999). Significance of collection and clinical consequences in HNPCC-patients. Viszeralchirurgie, 34(3), 129-133.

Nishioka, Y., Hirao, M., Robbins, P.D., Lotze, M.T., & Tahara, H. (1999). Induction of systemic and therapeutic antitumor immunity using intratumoral injection of dendritic cells genetically modified to express interleukin 12. CANCER RESEARCH, 59(16), 4035-4041.

Ohm, J.E., Shurin, M.R., Esche, C., Lotze, M.T., Carbone, D.P., & Gabrilovich, D.I. (1999). Effect of vascular endothelial growth factor and FLT3 ligand on dendritic cell generation in vivo. JOURNAL OF IMMUNOLOGY, 163(6), 3260-3268.

Okada, H., Giezeman-Smits, K.M., Tahara, H., Attanucci, J., Fellows, W.K., Lotze, M.T., Chambers, W.H., & Bozik, M.E. (1999). Effective cytokine gene therapy against an intracranial glioma using a retrovirally transduced IL-4 plus HSVtk tumor vaccine. GENE THERAPY, 6(2), 219-226.Springer Science and Business Media LLC. doi: 10.1038/sj.gt.3300798.

Osaki, T., Hashimoto, W., Gambotto, A., Okamura, H., Robbins, P.D., Kurimoto, M., Lotze, M.T., & Tahara, H. (1999). Potent antitumor effects mediated by local expression of the mature form of the interferon-γ inducing factor, interleukin-18 (IL-18). GENE THERAPY, 6(5), 808-815.Springer Science and Business Media LLC. doi: 10.1038/sj.gt.3300908.

Robertson, M.J., Cameron, C., Atkins, M.B., Gordon, M.S., Lotze, M.T., Sherman, M.L., & Ritz, J. (1999). Immunological effects of interleukin 12 administered by bolus intravenous injection to patients with cancer. CLINICAL CANCER RESEARCH, 5(1), 9-16.

Rosenberg, S.A., Blaese, R.M., Brenner, M.K., Deisseroth, A.B., Ledley, F.D., Lotze, M.T., Wilson, J.M., Nabel, G.J., Cornetta, K., Economou, J.S., Freeman, S.M., Riddell, S.R., Oldfield, E., Gansbacher, B., Dunbar, C., Walker, R.E., Schuening, F.G., Roth, J.A., Crystal, R.G., Welsh, M.J., Culver, K., Heslop, H.E., Simons, J., Wilmott, R.W., & Habib, N.A. (1999). Human gene marker/therapy clinical protocols. Hum Gene Ther, 10(18), 3067-3123.Mary Ann Liebert Inc. doi: 10.1089/10430349950016465.

Shurin, M.R., Lu, L., Kalinski, P., Stewart-Akers, A.M., & Lotze, M.T. (1999). Th1/Th2 balance in cancer, transplantation and pregnancy. Springer Seminars in Immunopathology, 21(3), 339-359. doi: 10.1007/BF00812261.

Tanaka, F., Hirao, M., & Lotze, M.T. (1999). Delivery of dendritic cells to sites of immune reactivity. Clinical Immunology Newsletter, 19(10-11), 128-131.Elsevier BV. doi: 10.1016/s0197-1859(00)87086-7.

Thomas, R.L., Matsko, C.M., Lotze, M.T., & Amoscato, A.A. (1999). Mass spectrometric identification of increased C16 ceramide levels during apoptosis. JOURNAL OF BIOLOGICAL CHEMISTRY, 274(43), 30580-30588.Elsevier BV. doi: 10.1074/jbc.274.43.30580.

Tüting, T., Gambotto, A., DeLeo, A., Lotze, M.T., Robbins, P.D., & Storkus, W.J. (1999). Induction of tumor antigen-specific immunity using plasmid DNA immunization in mice. CANCER GENE THERAPY, 6(1), 73-80.Springer Science and Business Media LLC. doi: 10.1038/sj.cgt.7700020.

Wilson, C.C., Olson, W.C., Tuting, T., Rinaldo, C.R., Lotze, M.T., & Storkus, W.J. (1999). HIV-1-specific CTL responses primed in vitro by blood-derived dendritic cells and Th1-biasing cytokines. JOURNAL OF IMMUNOLOGY, 162(5), 3070-3078.

Amoscato, A.A., Prenovitz, D.A., & Lotze, M.T. (1998). Rapid extracellular degradation of synthetic class I peptides by human dendritic cells. JOURNAL OF IMMUNOLOGY, 161(8), 4023-4032.

Couderc, B., Zitvogel, L., Douin-Echinard, V., Djennane, L., Tahara, H., Favre, G., Lotze, M.T., & Robbins, P.D. (1998). Enhancement of antitumor immunity by expression of CD70 (CD27 ligand) or CD154 (CD40 ligand) costimulatory molecules in tumor cells. CANCER GENE THERAPY, 5(3), 163-175.

Douin-Echinard, V., Robbins, P.D., Lotze, M.T., Favre, G., & Couderc, B. (1998). Enhancement of anti-tumor immunity by injection of fibroblasts genetically engineered to produce IL-12 and to express CD70. GENE THERAPY OF CANCER, 451, 353-357.Springer US. doi: 10.1007/978-1-4615-5357-1_55.

Esche, C., Subbotin, V.M., Maliszewski, C., Lotze, M.T., & Shurin, M.R. (1998). FLT3 ligand administration inhibits tumor growth in murine melanoma and lymphoma. CANCER RESEARCH, 58(3), 380-383.

Fernandez, N., Duffour, M.T., Perricaudet, M., Lotze, M.T., Tursz, T., & Zitvogel, L. (1998). Active specific T-cell-based immunotherapy for cancer: nucleic acids, peptides, whole native proteins, recombinant viruses, with dendritic cell adjuvants or whole tumor cell-based vaccines. Principles and future prospects. CYTOKINES CELLULAR & MOLECULAR THERAPY, 4(1), 53-65.

Finn, O.J., & Lotze, M.T. (1998). Third Keystone Symposium on Cellular Immunology and the Immunotherapy of Cancer - Introduction. JOURNAL OF IMMUNOTHERAPY, 21(2), 114-118.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-199803000-00004.

Goldman, S.A., Baker, E., Weyant, R.J., Clarke, M.R., Myers, J.N., & Lotze, M.T. (1998). Peritumoral CD1a-positive dendritic cells are associated with improved survival in patients with tongue carcinoma. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 124(6), 641-646.American Medical Association (AMA). doi: 10.1001/archotol.124.6.641.

Goydos, J.S., Brumfield, A.M., Frezza, E., Booth, A., Lotze, M.T., & Carty, S.E. (1998). Marked elevation of serum interleukin-6 in patients with cholangiocarcinoma - Validation of utility as a clinical marker. ANNALS OF SURGERY, 227(3), 398-404.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00000658-199803000-00012.

Iwazawa, T., Chau, G.Y., Mori, T., Robbins, P.D., Lotze, M.T., & Tahara, H. (1998). Effective gene therapy for liver tumors with intra-arterial injection of IL-12 gene-engineered fibroblasts (Preliminary study). Biotherapy, 12(12), 1543-1547.

Maeurer, M.J., & Lotze, M.T. (1998). Interleukin-7 (IL-7) knockout mice. Implications for lymphopoiesis and organ-specific immunity. Int Rev Immunol, 16(3-4), 309-322.Informa UK Limited. doi: 10.3109/08830189809042999.

Martincic, K., Campbell, R., Edwalds-Gilbert, G., Souan, L., Lotze, M.T., & Milcarek, C. (1998). Increase in the 64-kDa subunit of the polyadenylation/cleavage stimulatory factor during the G_o to S phase transition. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 95(19), 11095-11100.Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.95.19.11095.

Myers, J.N., Mank-Seymour, A., Zitvogel, L., Storkus, W., Clarke, M., Johnson, C.S., Tahara, H., & Lotze, M.T. (1998). Interleukin-12 gene therapy prevents establishment of SCC VII squamous cell carcinomas, inhibits tumor growth, and elicits long-term antitumor immunity in syngeneic C3H mice. LARYNGOSCOPE, 108(2), 261-268.Wiley. doi: 10.1097/00005537-199802000-00019.

Okada, H., Tahara, H., Shurin, M.R., Attanucci, J., Giezeman-Smits, K.M., Fellows, W.K., Lotze, M.T., Chambers, W.H., & Bozik, M.E. (1998). Bone marrow-derived dendritic cells pulsed with a tumor-specific peptide elicit effective anti-tumor immunity against intracranial neoplasms. International Journal of Cancer, 78(2), 196-201. doi: 10.1002/(SICI)1097-0215(19981005)78:2<196::AID-IJC13>3.0.CO;2-9.

Osaki, T., Péron, J.M., Cai, Q., Okamura, H., Robbins, P.D., Kurimoto, M., Lotze, M.T., & Tahara, H. (1998). IFN-γ-inducing factor/IL-18 administration mediates IFN-γ- and IL-12- independent antitumor effects. Journal of Immunology, 160(4), 1742-1749.

Péron, J.M., Esche, C., Subbotin, V.M., Maliszewski, C., Lotze, M.T., & Shurin, M.R. (1998). FLT3-ligand administration inhibits liver metastases:: Role of NK cells. JOURNAL OF IMMUNOLOGY, 161(11), 6164-6170.

Rao, U.N.M., Hanan, S.H., Lotze, M.T., & Karakousis, C.P. (1998). Distant skin and soft tissue metastases from sarcomas. JOURNAL OF SURGICAL ONCOLOGY, 69(2), 94-98.Wiley. doi: 10.1002/(sici)1096-9098(199810)69:2<94::aid-jso9>3.0.co;2-4.

Shurin, G.V., Gerein, V., Lotze, M.T., & Barksdale, E.M. (1998). Apoptosis induced in T cells by human neuroblastoma cells: Role of Fas ligand. NATURAL IMMUNITY, 16(5-6), 263-274.S. Karger AG. doi: 10.1159/000069452.

Shurin, M.R., Esche, C., & Lotze, M.T. (1998). FLT3: Receptor and ligand. Biology and potential clinical application. CYTOKINE & GROWTH FACTOR REVIEWS, 9(1), 37-48.Elsevier BV. doi: 10.1016/S1359-6101(97)00035-X.

Takayama, T., Nishioka, Y., Lu, L., Lotze, M.T., Tahara, H., & Thomson, A.W. (1998). Retroviral delivery of viral interleukin-10 into myeloid dendritic cells markedly inhibits their allostimulatory activity and promotes the induction of T-cell hyporesponsiveness. TRANSPLANTATION, 66(12), 1567-1574.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00007890-199812270-00001.

Tjandrawan, T., Martin, D.M., Maeurer, M.J., Castelli, C., Lotze, M.T., & Storkus, W.J. (1998). Autologous human dendriphages pulsed with synthetic or natural tumor peptides elicit tumor-specific CTLs in vitro. JOURNAL OF IMMUNOTHERAPY, 21(2), 149-157.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-199803000-00009.

Tjandrawan, T., Martin, D.M., Maeurer, M.J., Castelli, C., Lotze, M.T., & Storkus, W.J. (1998). Third keystone symposium on cellular immunology and the immunotherapy of cancer antigen processing and presentation autologous human dendriphages pulsed with synthetic or natural tumor peptides elicit tumor-specific CTLs in vitro. Journal of Immunotherapy, 21(2), 157-149. doi: 10.1097/00002371-199803000-00009.

Tüting, T., Wilson, C.C., Martin, D.M., Baar, J., DeLeo, A., Lotze, M.T., & Storkus, W.J. (1998). DNA vaccines targeting dendritic cells for the immunotherapy of cancer. GENE THERAPY OF CANCER, 451, 295-304.Springer US. doi: 10.1007/978-1-4615-5357-1_46.

Tüting, T., Wilson, C.C., Martin, D.M., Kasamon, Y.L., Rowles, J., Ma, D.I., Slingluff, C.L., Wagner, S.N., van der Bruggen, P., Baar, J., Lotze, M.T., & Storkus, W.J. (1998). Autologous human monocyte-derived dendritic cells genetically modified to express melanoma antigens elicit primary cytotoxic T cell responses in vitro:: Enhancement by cotransfection of genes encoding the Th1-biasing cytokines IL-12 and IFN-α. JOURNAL OF IMMUNOLOGY, 160(3), 1139-1147.

Vokes, E.E., Figlin, R., Hochster, H., Lotze, M., & Rybak, M.E. (1998). A phase II study of recombinant human interleukin-4 for advanced or recurrent non-small cell lung cancer. Cancer J Sci Am, 4(1), 46-51.

Vu, H.N., Jenkins, F.W., Swerdlow, S.H., Locker, J., & Lotze, M.T. (1998). Pleural effusion as the presentation for primary effusion lymphoma. SURGERY, 123(5), 589-591.Elsevier BV. doi: 10.1067/msy.1998.88087.

Zitvoge, L., Fernandez, N., & Lotze, M.T. (1998). Immunothérapie du cancer par thérapie cellulaire dendritique : Des bases précliniques à la préparation d'essais thérapeutiques. Hematologie, 4(6), 490-491.

Atkins, M.B., Robertson, M.J., Gordon, M., Lotze, M.T., DeCoste, M., DuBois, J.S., Ritz, J., Sandler, A.B., Edington, H.D., Garzone, P.D., Mier, J.W., Canning, C.M., Battiato, L., Tahara, H., & Sherman, M.L. (1997). Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies. CLINICAL CANCER RESEARCH, 3(3), 409-417.

Dookeran, K.A., Lotze, M.T., Sikora, S.S., & Rao, U.N.M. (1997). Pancreatic and ampullary carcinomas with intrascrotal metastases. BRITISH JOURNAL OF SURGERY, 84(2), 198-199.Oxford University Press (OUP). doi: 10.1046/j.1365-2168.1997.02469.x.

Dutcher, J.P., Atkins, M., Fisher, R., Weiss, G., Margolin, K., Aronson, F., Sosman, J., Lotze, M., Gordon, M., Logan, T., & Mier, J. (1997). Interleukin-2-based therapy for metastatic renal cell cancer: the Cytokine Working Group experience, 1989-1997. Cancer J Sci Am, 3 Suppl 1(SUPPL. 1), S73-S78.

Kim, S.H., An, C.S., Tahara, H., Park, C., Lotze, M.T., Robbins, P.D., & Kim, S. (1997). Retroviral-mediated IL-12 gene therapy for advanced murine tumors. EXPERIMENTAL AND MOLECULAR MEDICINE, 29(1), 53-58.Springer Science and Business Media LLC. doi: 10.1038/emm.1997.8.

Lotze, M.T. (1997). Future directions for recombinant interleukin-2 in cancer: A chronic inflammatory disorder. CANCER JOURNAL FROM SCIENTIFIC AMERICAN, 3, S106-S108.

Lotze, M.T. (1997). Getting to the source: Dendritic cells as therapeutic reagents for the treatment of patients with cancer. ANNALS OF SURGERY, 226(1), 1-5.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00000658-199707000-00001.

Lotze, M.T. (1997). Interleukin-2. 2, 1-47.Elsevier. doi: 10.1016/s1874-5687(97)80022-5.

Lotze, M.T., Hellerstedt, B., Stolinski, L., Tueting, T., Wilson, C., Kinzler, D., Vu, H., Rubin, J.T., Storkus, W., Tahara, H., Elder, E., & Whiteside, T. (1997). The role of interleukin-2, interleukin-12, and dendritic cells in cancer therapy. CANCER JOURNAL FROM SCIENTIFIC AMERICAN, 3(SUPPL. 1), S109-S114.

Lotze, M.T., Shurin, M., Davis, I., Amoscato, A., & Storkus, W.J. (1997). Dendritic cell based therapy of cancer. DENDRITIC CELLS IN FUNDAMENTAL AND CLINICAL IMMUNOLOGY, VOL 3, 417, 551-569.Springer US. doi: 10.1007/978-1-4757-9966-8_91.

Maeurer, M.J., & Lotze, M.T. (1997). Tumor Recognition by the Cellular Immune System: New Aspects of Tumor Immunology. International Reviews of Immunology, 14(42038), 97-132. doi: 10.3109/08830189709116848.

Maeurer, M.J., Walter, W., Martin, D., Zitvogel, L., Elder, E., Storkus, W., & Lotze, M.T. (1997). Interleukin-7 (IL-7) in colorectal cancer: IL-7 is produced by tissues from colorectal cancer and promotes preferential expansion of tumour infiltrating lymphocytes. SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 45(2), 182-192.Wiley. doi: 10.1046/j.1365-3083.1997.d01-384.x.

Margolin, K., Atkins, M., Sparano, J., Sosman, J., Weiss, G., Lotze, M., Doroshow, J., Mier, J., O'Boyle, K., Fisher, R., Campbell, E., Rubin, J., Federighi, D., & Bursten, S. (1997). Prospective randomized trial of lisofylline for the prevention of toxicities of high-dose interleukin 2 therapy in advanced renal cancer and malignant melanoma. Clin Cancer Res, 3(4), 565-572.

Mayordomo, J.I., Zorina, T., Storkus, W.J., Zitvogel, L., GarciaPrats, M.D., DeLeo, A.B., & Lotze, M.T. (1997). Bone marrow-derived dendritic cells serve as potent adjuvants for peptide-based antitumor vaccines. STEM CELLS, 15(2), 94-103.Oxford University Press (OUP). doi: 10.1002/stem.150094.

Park, C., Kang, W.K., Oh, M., Kim, W.S., Yang, J.H., Lotze, M.T., Kim, S., Park, K., & Park, C.H. (1997). Production of IL-12 from gene modified human dermal fibroblasts: A preclinical study for IL-12 cancer gene therapy. EXPERIMENTAL AND MOLECULAR MEDICINE, 29(1), 65-69.Springer Science and Business Media LLC. doi: 10.1038/emm.1997.10.

Rosenberg, S.A., Blaese, R.M., Brenner, M.K., Deisseroth, A.B., Ledley, F.D., Lotze, M.T., Wilson, J.M., Nabel, G.J., Cornetta, K., Economou, J.S., Freeman, S.M., Riddell, S.R., Oldfield, E., Gansbacher, B., Dunbar, C., Walker, R.E., Schuening, F.G., Roth, J.A., Crystal, R.G., Welsh, M.J., Culver, K., Heslop, H.E., Simons, J., Wilmott, R.W., & Boucher, R.C. (1997). Human gene marker/therapy clinical protocols. Hum Gene Ther, 8(18), 2301-2338.Mary Ann Liebert Inc. doi: 10.1089/hum.1997.8.18-2301.

Shurin, M.R., Esche, C., Peron, J.M., & Lotze, M.T. (1997). Antitumor activities of IL-12 and mechanisms of action. IL-12, 68, 153-174.KARGER. doi: 10.1159/000058690.

Shurin, M.R., Pandharipande, P.P., Zorina, T.D., Haluszczak, C., Subbotin, V.M., Hunter, O., Brumfield, A., Storkus, W.J., Maraskovsky, E., & Lotze, M.T. (1997). FLT3 ligand induces the generation of functionally active dendritic cells in mice. CELLULAR IMMUNOLOGY, 179(2), 174-184.Elsevier BV. doi: 10.1006/cimm.1997.1152.

Tuting, T., DeLeo, A.B., Lotze, M.T., & Storkus, W.J. (1997). Genetically modified bone marrow-derived dendritic cells expressing tumor-associated viral or ''self'' antigens induce antitumor immunity in vivo. EUROPEAN JOURNAL OF IMMUNOLOGY, 27(10), 2702-2707.Wiley. doi: 10.1002/eji.1830271033.

Tuting, T., Gambotto, A., Baar, J., Davis, I.D., Storkus, W.J., Zavodny, P.J., Narula, S., Tahara, H., Robbins, P.D., & Lotze, M.T. (1997). Interferon-alpha gene therapy for cancer: retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene delivery in murine tumor models. GENE THERAPY, 4(10), 1053-1060.Springer Science and Business Media LLC. doi: 10.1038/sj.gt.3300509.

Tuting, T., Storkus, W.J., & Lotze, M.T. (1997). Gene-based strategies for the immunotherapy of cancer. JOURNAL OF MOLECULAR MEDICINE-JMM, 75(7), 478-491.Springer Science and Business Media LLC. doi: 10.1007/s001090050133.

Amoscato, A.A., Storkus, W.J., & Lotze, M.T. (1996). Secretion of a 93 kda gelatinase by human peripheral blood dendritic cells. FASEB JOURNAL, 10(6), 2787.

Berman, R.M., Suzuki, T., Tahara, H., Robbins, P.D., Narula, S.K., & Lotze, M.T. (1996). Systemic administration of cellular IL-10 induces an effective, specific, and long-lived immune response against established tumors in mice. JOURNAL OF IMMUNOLOGY, 157(1), 231-238.

Bernhard, H., Maeurer, M.J., Jager, E., Wolfel, T., Schneider, J., Karbach, J., Seliger, B., Huber, C., Storkus, W.S., Lotze, M.T., zumBuschenfelde, K.H.M., & Knuth, A. (1996). Recognition of human renal cell carcinoma and melanoma by HLA-A2-restricted cytotoxic T lymphocytes is mediated by shared peptide epitopes and up-regulated by interferon-gamma. SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 44(3), 285-292.Wiley. doi: 10.1046/j.1365-3083.1996.d01-304.x.

Bozik, M.E., Chambers, W.H., Gilbert, M., & Lotze, M.T. (1996). Treatment of 9L gliosarcoma with IL-4 producing 9L vaccine. FASEB JOURNAL, 10(6), 2385.

Celluzzi, C.M., Mayordomo, J.I., Storkus, W.J., Lotze, M.T., & Falo, L.D. (1996). Peptide-pulsed dendritic cells induce antigen-specific, CTL-mediated protective tumor immunity. JOURNAL OF EXPERIMENTAL MEDICINE, 183(1), 283-287.Rockefeller University Press. doi: 10.1084/jem.183.1.283.

Dumanian, G.A., Llull, R., Ramasastry, S.S., Greco, R.J., Lotze, M.T., & Edington, H. (1996). Postoperative abdominal wall defects with enterocutaneous fistulae. AMERICAN JOURNAL OF SURGERY, 172(4), 332-334.Elsevier BV. doi: 10.1016/S0002-9610(96)00201-2.

Elder, E.M., Lotze, M.T., & Whiteside, T.L. (1996). Successful culture and selection of cytokine gene-modified human dermal fibroblasts for the biologic therapy of patients with cancer. HUMAN GENE THERAPY, 7(4), 479-487.Mary Ann Liebert Inc. doi: 10.1089/hum.1996.7.4-479.

Evans, C.H., Mankin, H.J., Ferguson, A.B., Robbins, P.D., Ghivizzani, S.C., Herndon, J.H., Kang, R., Tomaino, M.M., & Wright, T.M. (1996). Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis. HUMAN GENE THERAPY, 7(10), 1261-1280.Mary Ann Liebert Inc. doi: 10.1089/hum.1996.7.10-1261.

Galon, J., Gauchat, J.F., Mazieres, N., Spagnoli, R., Storkus, W., Lotze, M., Bonnefoy, J.Y., Fridman, W.H., & Sautes, C. (1996). Soluble Fc gamma receptor type III (Fc gamma RIII, CD16) triggers cell activation through interaction with complement receptors. JOURNAL OF IMMUNOLOGY, 157(3), 1184-1192.

Goydos, J.S., Elder, E., Whiteside, T.L., Finn, O.J., & Lotze, M.T. (1996). A phase I trial of a synthetic mucin peptide vaccine induction of specific immune reactivity in patients with adenocarcinoma. JOURNAL OF SURGICAL RESEARCH, 63(1), 298-304.Elsevier BV. doi: 10.1006/jsre.1996.0264.

Leder, G.H., Oppenheim, M., Rosenstein, M., Shah, N., Hoffman, R., Lotze, M.T., & Beger, H.G. (1996). Inhibition of nitric oxide synthesis does not improve interleukin-2-mediated antitumor effects in vivo. EUROPEAN SURGICAL RESEARCH, 28(3), 167-178.S. Karger AG. doi: 10.1159/000129455.

Lotze, M.T. (1996). Interleukin 12: Cellular and molecular immunology of an important regulatory cytokine - Introduction. INERLEUKIN 12: CELLULAR AND MOLECULAR IMMUNOLOGY OF AN IMPORTANT REGULATORY CYTOKINE, 795(1), XIII-XIX.Wiley. doi: 10.1111/j.1749-6632.1996.tb52649.x.

Lotze, M.T. (1996). Cytokine gene therapy of cancer. Cancer J Sci Am, 2(2), 63-72.

Lotze, M.T., Zitvogel, L., Campbell, R., Robbins, P.D., Elder, E., Haluszczak, C., Martin, D., Whiteside, T.L., Storkus, W.J., & Tahara, H. (1996). Cytokine gene therapy of cancer using interleukin-12: Murine and clinical trials. INERLEUKIN 12: CELLULAR AND MOLECULAR IMMUNOLOGY OF AN IMPORTANT REGULATORY CYTOKINE, 795(1), 440-454.Wiley. doi: 10.1111/j.1749-6632.1996.tb52715.x.

Maeurer, M.J., Chan, H.W., Karbach, J., Salter, R.D., Knuth, A., Lotze, M.T., & Storkus, W.J. (1996). Amino acid substitutions at position 97 in HLA-A2 segregate cytolysis from cytokine release in MART-1/Melan-A peptide AAGIGILTV-specific cytotoxic T lymphocytes. EUROPEAN JOURNAL OF IMMUNOLOGY, 26(11), 2613-2623.Wiley. doi: 10.1002/eji.1830261112.

Maeurer, M.J., Gollin, S.M., Martin, D., Swaney, W., Bryant, J., Castelli, C., Robbins, P., Parmiani, G., Storkus, W.J., & Lotze, M.T. (1996). Tumor escape from immune recognition - Lethal recurrent melanoma in a patient associated with downregulation of the peptide transporter protein TAP-1 and loss of expression of the immunodominant MART-1/Melan-A antigen. JOURNAL OF CLINICAL INVESTIGATION, 98(7), 1633-1641.American Society for Clinical Investigation. doi: 10.1172/JCI118958.

Maeurer, M.J., Gollin, S.M., Storkus, W.J., Swaney, W., Karbach, J., Martin, D., Castelli, C., Salter, R., Knuth, A., & Lotze, M.T. (1996). Tumor escape from immune recognition: Loss of HLA-A2 melanoma cell surface expression is associated with a complex rearrangement of the short arm of chromosome 6(1). CLINICAL CANCER RESEARCH, 2(4), 641-652.

Maeurer, M.J., Martin, D., Elder, E., Storkus, W.J., & Lotze, M.T. (1996). Detection of naturally processed and HLA-A1-presented melanoma T-cell epitopes defined by CD8(+) T-cells' release of granulocyte-macrophage colony-stimulating factor but not by cytolysis. CLINICAL CANCER RESEARCH, 2(1), 87-95.

Maeurer, M.J., Martin, D., Walter, W., Liu, K.H., Zitvogel, L., Halusczcak, K., Rabinowich, H., Duquesnoy, R., Storkus, W., & Lotze, M.T. (1996). Human intestinal V delta 1(+) T lymphocytes recognize tumor cells of epithelial origin. JOURNAL OF EXPERIMENTAL MEDICINE, 183(4), 1681-1696.Rockefeller University Press. doi: 10.1084/jem.183.4.1681.

Maeurer, M.J., Storkus, W.J., Kirkwood, J.M., & Lotze, M.T. (1996). New treatment options for patients with melanoma: Review of melanoma-derived T-cell epitope-based peptide vaccines. MELANOMA RESEARCH, 6(1), 11-24.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00008390-199602000-00003.

Mayordomo, J.I., Loftus, D.J., Sakamoto, H., DeCesare, C.M., Appasamy, P.M., Lotze, M.T., Storkus, W.J., Appella, E., & DeLeo, A.B. (1996). Therapy of murine tumors with p53 wild-type and mutant sequence peptide-based vaccines. JOURNAL OF EXPERIMENTAL MEDICINE, 183(4), 1357-1365.Rockefeller University Press. doi: 10.1084/jem.183.4.1357.

Mertz, P.M., Corcoran, M.L., McCluskey, K.M., Zhang, Y.H., Wong, H.L., Lotze, M.T., DeWitt, D.L., Wahl, S.M., & Wahl, L.M. (1996). Suppression of prostaglandin H synthase-2 induction in human monocytes by in vitro or in vivo administration of interleukin 4. CELLULAR IMMUNOLOGY, 173(2), 252-260.Elsevier BV. doi: 10.1006/cimm.1996.0275.

Myers, J.N., Yasumura, S., Suminami, Y., Hirabayashi, H., Lin, W.C., Johnson, J.T., Lotze, M.T., & Whiteside, T.L. (1996). Growth stimulation of human head and neck squamous cell carcinoma cell lines by interleukin 4. CLINICAL CANCER RESEARCH, 2(1), 127-135.

Qin, L.H., Chavin, K.D., Ding, Y.Z., Tahara, H., Favaro, J.P., Woodward, J.E., Suzuki, T., Robbins, P.D., Lotze, M.T., & Bromberg, J.S. (1996). Retrovirus-mediated transfer of viral IL-10 gene prolongs murine cardiac allograft survival. JOURNAL OF IMMUNOLOGY, 156(6), 2316-2323.

Rosenberg, S.A., Blaese, R.M., Brenner, M.K., Deisseroth, A.B., Ledley, F.D., Lotze, M.T., Wilson, J.M., Nabel, G.J., Cornetta, K., Economou, J.S., Freeman, S.M., Riddell, S.R., Oldfield, E., Gansbacher, B., Dunbar, C., Walker, R.E., Schuening, F.G., Roth, J.A., Crystal, R.G., Welsh, M.J., Culver, K., Heslop, H.E., Simons, J., Wilmott, R.W., & Aebischer, P. (1996). Human gene marker/therapy clinical protocols. Hum Gene Ther, 7(13), 1621-1647.Mary Ann Liebert Inc. doi: 10.1089/hum.1996.7.13-1621.

Rosenberg, S.A., Blaese, R.M., Brenner, M.K., Deisseroth, A.B., Ledley, F.D., Lotze, M.T., Wilson, J.M., Nabel, G.J., Cornetta, K., Economou, J.S., Freeman, S.M., Riddell, S.R., Oldfield, E., Gansbacher, B., Dunbar, C., Walker, R.E., Schuening, F.G., Roth, J.A., Crystal, R.G., Welsh, M.J., Culver, K., Heslop, H.E., Simons, J., Wilmott, R.W., & Tiberghien, P. (1996). Human gene marker/therapy clinical protocols. Hum Gene Ther, 7(18), 2287-2313.Mary Ann Liebert Inc. doi: 10.1089/hum.1996.7.18-2287.

Sikora, S.S., Samsonov, M.E., Dookeran, K.A., Edington, H., & Lotze, M.T. (1996). Peripheral nerve entrapment: An unusual adverse event with high-dose interleukin-2 therapy. ANNALS OF ONCOLOGY, 7(5), 535-536.Elsevier BV. doi: 10.1093/oxfordjournals.annonc.a010647.

Tahara, H., Zitvogel, L., Storkus, W.J., Robbins, P.D., & Lotze, M.T. (1996). Murine models of cancer cytokine gene therapy using interleukin-12. INERLEUKIN 12: CELLULAR AND MOLECULAR IMMUNOLOGY OF AN IMPORTANT REGULATORY CYTOKINE, 795(1), 275-283.Wiley. doi: 10.1111/j.1749-6632.1996.tb52677.x.

Zitvogel, L., Couderc, B., Mayordomo, J.I., Robbins, P.D., Lotze, M.T., & Storkus, W.J. (1996). IL-12-engineered dendritic cells serve as effective tumor vaccine adjuvants in vivo. INERLEUKIN 12: CELLULAR AND MOLECULAR IMMUNOLOGY OF AN IMPORTANT REGULATORY CYTOKINE, 795(1), 284-293.Wiley. doi: 10.1111/j.1749-6632.1996.tb52678.x.

Zitvogel, L., Mayordomo, J.I., Tjandrawan, T., DeLeo, A.B., Clarke, M.R., Lotze, M.T., & Storkus, W.J. (1996). Therapy of murine tumors with tumor peptide-pulsed dendritic cells: Dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines. JOURNAL OF EXPERIMENTAL MEDICINE, 183(1), 87-97.Rockefeller University Press. doi: 10.1084/jem.183.1.87.

Zitvogel, L., Robbins, P.D., Storkus, W.J., Clarke, M.R., Maeurer, M.J., Campbell, R.L., Davis, C.G., Tahara, H., Schreiber, R.D., & Lotze, M.T. (1996). Interleukin-12 and B7.1 co-stimulation cooperate in the induction of effective antitumor immunity and therapy of established tumors. EUROPEAN JOURNAL OF IMMUNOLOGY, 26(6), 1335-1341.Wiley. doi: 10.1002/eji.1830260624.

CAI, Q., RUBIN, J.T., & LOTZE, M.T. (1995). GENETICALLY MARKING HUMAN-CELLS - RESULTS OF THE FIRST CLINICAL GENE-TRANSFER STUDIES. CANCER GENE THERAPY, 2(2), 125-136.

CASTELLI, C., STORKUS, W.J., MAEURER, M.J., MARTIN, D.M., HUANG, E.C., PRAMANIK, B.N., NAGABHUSHAN, T.L., PARMIANI, G., & LOTZE, M.T. (1995). MASS-SPECTROMETRIC IDENTIFICATION OF A NATURALLY PROCESSED MELANOMA PEPTIDE RECOGNIZED BY CD8(+) CYTOTOXIC T-LYMPHOCYTES. JOURNAL OF EXPERIMENTAL MEDICINE, 181(1), 363-368.Rockefeller University Press. doi: 10.1084/jem.181.1.363.

FRASSANITO, M.A., MAYORDOMO, J.I., DELEO, R.M., STORKUS, W.J., LOTZE, M.T., & DELEO, A.B. (1995). IDENTIFICATION OF METH-A SARCOMA-DERIVED CLASS-I MAJOR HISTOCOMPATIBILITY COMPLEX-ASSOCIATED PEPTIDES RECOGNIZED BY A SPECIFIC CD8(+) CYTOTOXIC T-LYMPHOCYTE. CANCER RESEARCH, 55(1), 124-128.

LEDER, G.H., OPPENHEIM, M., ROSENSTEIN, M., LOTZE, M.T., & BERGER, H.G. (1995). ADDITION OF INTERLEUKIN-12 TO LOW-DOSE INTERLEUKIN-2 TREATMENT IMPROVES ANTITUMOR EFFICACY IN-VIVO. ZEITSCHRIFT FUR GASTROENTEROLOGIE, 33(9), 499-502.

Maeurer, M., Zitvogel, L., Elder, E., Storkus, W.J., & Lotze, M.T. (1995). Human intestinal V(delta)1+T cells obtained from patients with colon cancer respond exclusively to SEB but not to SEA. NATURAL IMMUNITY, 14(4), 188-197.

Maeurer, M.J., Hurd, S., Martin, D.M., Storkus, W.J., & Lotze, M.T. (1995). Cytolytic T-cell clones define HLA-A2-restricted human cutaneous melanoma peptide epitopes: correlation with T-cell receptor usage. Cancer J Sci Am, 1(2), 162-170.

MAEURER, M.J., MARTIN, D.M., CASTELLI, C., ELDER, E., LEDER, G., STORKUS, W.J., & LOTZE, M.T. (1995). HOST IMMUNE-RESPONSE IN RENAL-CELL CANCER - INTERLEUKIN-4 (IL-4) AND IL-10 MESSENGER-RNA ARE FREQUENTLY DETECTED IN FRESHLY COLLECTED TUMOR-INFILTRATING LYMPHOCYTES. CANCER IMMUNOLOGY IMMUNOTHERAPY, 41(2), 111-121.Springer Science and Business Media LLC. doi: 10.1007/BF01527407.

MAEURER, M.J., MARTIN, D.M., STORKUS, W.J., & LOTZE, M.T. (1995). TCR USAGE IN CTLS RECOGNIZING MELANOMA MELANOCYTE ANTIGENS. IMMUNOLOGY TODAY, 16(12), 603-604.Elsevier BV. doi: 10.1016/0167-5699(95)80084-0.

MAYORDOMO, J.I., ZORINA, T., STORKUS, W.J., ZITVOGEL, L., CELLUZZI, C., FALO, L.D., MELIEF, C.J., ILDSTAD, S.T., KAST, W.M., DELEO, A.B., & LOTZE, M.T. (1995). BONE-MARROW-DERIVED DENDRITIC CELLS PULSED WITH SYNTHETIC TUMOR PEPTIDES ELICIT PROTECTIVE AND THERAPEUTIC ANTITUMOR IMMUNITY. NATURE MEDICINE, 1(12), 1297-1302.Springer Science and Business Media LLC. doi: 10.1038/nm1295-1297.

NISHIHARA, K., BARTH, R.F., WILKIE, N., LANG, J.C., ODA, Y., KIKUCHI, H., EVERSON, M.P., & LOTZE, M.T. (1995). INCREASED IN-VITRO AND IN-VIVO TUMORICIDAL ACTIVITY OF A MACROPHAGE CELL-LINE GENETICALLY-ENGINEERED TO EXPRESS IFN-GAMMA, IL-4, IL-6, OR TNF-ALPHA. CANCER GENE THERAPY, 2(2), 113-124.

PAPPO, I., TAHARA, H., ROBBINS, P.D., GATELY, M.K., WOLF, S.F., BARNEA, A., & LOTZE, M.T. (1995). ADMINISTRATION OF SYSTEMIC OR LOCAL INTERLEUKIN-2 ENHANCES THE ANTITUMOR EFFECTS OF INTERLEUKIN-12 GENE-THERAPY. JOURNAL OF SURGICAL RESEARCH, 58(2), 218-226.Elsevier BV. doi: 10.1006/jsre.1995.1034.

QIN, L.H., CHAVIN, K.D., DING, Y.Z., FAVARO, J.P., WOODWARD, J.E., LIN, J.X., TAHARA, H., ROBBINS, P., SHAKED, A., HO, D.Y., SAPOLSKY, R.M., LOTZE, M.T., & BROMBERG, J.S. (1995). MULTIPLE VECTORS EFFECTIVELY ACHIEVE GENE-TRANSFER IN A MURINE CARDIAC TRANSPLANTATION MODEL - IMMUNOSUPPRESSION WITH TGF-BETA-1 OR VIL-10. TRANSPLANTATION, 59(6), 809-816.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00007890-199503270-00002.

Rubin, J.T., Day, R., Duquesnoy, R., Simonis, B., Adams, S., Lee, J., & Lotze, M.T. (1995). HLA-DQ1 is associated with clinical response and survival of patients with melanoma who are treated with interleukin-2. Ther Immunol, 2(1), 1-6.

RUBIN, J.T., LOTZE, M.T., ROSENFELDER, D., BRUMFIELD, A., HOWELLS, R., SCHWARTZ, R., SYLVESTRI, S., SAMMON, J., BRON, K., ORENS, P., ZAJKO, A., SWANSON, D., & DAY, R. (1995). TREATMENT OF HEPATIC-METASTATIC COLORECTAL-CANCER WITH A CHEMOTHERAPEUTIC EMULSION - INTERIM RESULTS OF A PHASE-I TRIAL. ANNALS OF SURGICAL ONCOLOGY, 2(4), 351-359.Springer Science and Business Media LLC. doi: 10.1007/BF02307069.

SUMINAMI, Y., ELDER, E.M., LOTZE, M.T., & WHITESIDE, T.L. (1995). IN-SITU INTERLEUKIN-4 GENE-EXPRESSION IN CANCER-PATIENTS TREATED WITH GENETICALLY-MODIFIED TUMOR VACCINE. JOURNAL OF IMMUNOTHERAPY, 17(4), 238-248.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-199505000-00006.

SUZUKI, T., TAHARA, H., NARULA, S., MOORE, K.W., ROBBINS, P.D., & LOTZE, M.T. (1995). VIRAL INTERLEUKIN-10 (IL-10), THE HUMAN HERPES-VIRUS-4 CELLULAR IL-10 HOMOLOG, INDUCES LOCAL ANERGY TO ALLOGENEIC AND SYNGENEIC TUMORS. JOURNAL OF EXPERIMENTAL MEDICINE, 182(2), 477-486.Rockefeller University Press. doi: 10.1084/jem.182.2.477.

TAHARA, H., & LOTZE, M.T. (1995). ANTITUMOR EFFECTS OF INTERLEUKIN-12 (IL-12) - APPLICATIONS FOR THE IMMUNOTHERAPY AND GENE-THERAPY OF CANCER. GENE THERAPY, 2(2), 96-106.

Tahara, H., Lotze, M., Robbins, P.D., Storkus, W.J., & Zitvogel, L. (1995). IL-12 gene therapy using direct injection of tumors with genetically engineered autologous fibroblasts. HUMAN GENE THERAPY, 6(12), 1607-1624.Mary Ann Liebert Inc. doi: 10.1089/hum.1995.6.12-1607.

TAHARA, H., ZITVOGEL, L., STORKUS, W.J., ZEH, H.J., MCKINNEY, T.G., SCHREIBER, R.D., GUBLER, U., ROBBINS, P.D., & LOTZE, M.T. (1995). EFFECTIVE ERADICATION OF ESTABLISHED MURINE TUMORS WITH IL-12 GENE-THERAPY USING A POLYCISTRONIC RETROVIRAL VECTOR. JOURNAL OF IMMUNOLOGY, 154(12), 6466-6474.

Zitvogel, L., & Lotze, M.T. (1995). Role of interleukin-12 (IL12) as an anti-tumour agent: Experimental biology and clinical application. RESEARCH IN IMMUNOLOGY, 146(7-8), 628-635.Elsevier BV. doi: 10.1016/0923-2494(96)83041-0.

ZITVOGEL, L., TAHARA, H., ROBBINS, P.D., STORKUS, W.J., CLARKE, M.R., NALESNIK, M.A., & LOTZE, M.T. (1995). CANCER-IMMUNOTHERAPY OF ESTABLISHED TUMORS WITH IL-12 - EFFECTIVE DELIVERY BY GENETICALLY-ENGINEERED FIBROBLASTS. JOURNAL OF IMMUNOLOGY, 155(3), 1393-1403.

DIBISCEGLIE, A.M., SIMPSON, L.H., LOTZE, M.T., & HOOFNAGLE, J.H. (1994). DEVELOPMENT OF HEPATOCELLULAR-CARCINOMA AMONG PATIENTS WITH CHRONIC LIVER-DISEASE DUE TO HEPATITIS-C VIRAL-INFECTION. JOURNAL OF CLINICAL GASTROENTEROLOGY, 19(3), 222-226.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00004836-199410000-00011.

IRSHAID, Y., ADEDOYIN, A., LOTZE, M., & BRANCH, R.A. (1994). MONOACETYLDAPSONE INHIBITION OF DAPSONE N-HYDROXYLATION BY HUMAN AND RAT-LIVER MICROSOMES. DRUG METABOLISM AND DISPOSITION, 22(1), 161-164.

ITOH, T., STORKUS, W.J., GORELIK, E., & LOTZE, M.T. (1994). PARTIAL-PURIFICATION OF MURINE TUMOR-ASSOCIATED PEPTIDE EPITOPES COMMON TO HISTOLOGICALLY DISTINCT TUMORS, MELANOMA AND SARCOMA, THAT ARE PRESENTED BY H-2K(B) MOLECULES AND RECOGNIZED BY CD8+ TUMOR-INFILTRATING LYMPHOCYTES. JOURNAL OF IMMUNOLOGY, 153(3), 1202-1215.

Leder, G.H., Storkus, W.J., Stuber, G., Modrow, S., & Lotze, M.T. (1994). Erratum: (Langenbecks Archiv fur Chirurgie, Forumband 1994). Langenbecks Archiv fur Chirurgie, 379(4), 254.

Lotze, M.T. (1994). Molecular biology and clinical applications to cancer. Curr Opin Gen Surg, 245-254.

Lotze, M.T., Agarwala, S.S., & Kirkwood, J.M. (1994). Clinical applications of IL-2: Commentary I. ONCOLOGY, 8(6).

LOTZE, M.T., RUBIN, J.T., CARTY, S., EDINGTON, H., FERSON, P., LANDRENEAU, R., PIPPIN, B., POSNER, M., ROSENFELDER, D., WATSON, C., CARLOS, T., KIRKWOOD, J., LEMBERSKY, B., LOGAN, T., ROSENSTEIN, M., RYBAK, M.E., WHITESIDE, T., ELDER, E., MOEN, R.C., JACOB, W., CHEN, Y.W., PINKUS, R.L., & BRYANT, J. (1994). GENE-THERAPY OF CANCER - A PILOT-STUDY OF IL-4-GENE-MODIFIED FIBROBLASTS ADMIXED WITH AUTOLOGOUS TUMOR TO ELICIT AN IMMUNE-RESPONSE. HUMAN GENE THERAPY, 5(1), 41-55.Mary Ann Liebert Inc. doi: 10.1089/hum.1994.5.1-41.

NASTALA, C.L., EDINGTON, H.D., MCKINNEY, T.G., TAHARA, H., NALESNIK, M.A., BRUNDA, M.J., GATELY, M.K., WOLF, S.F., SCHREIBER, R.D., STORKUS, W.J., & LOTZE, M.T. (1994). RECOMBINANT IL-12 ADMINISTRATION INDUCES TUMOR-REGRESSION IN ASSOCIATION WITH IFN-GAMMA PRODUCTION. JOURNAL OF IMMUNOLOGY, 153(4), 1697-1706.

Oppenheim, M.H., & Lotze, M.T. (1994). lnterleukin-2: Solid-Tumor Therapy. Oncology, 51(2), 154-169.S. Karger AG. doi: 10.1159/000227330.

PIPPIN, B.A., ROSENSTEIN, M., JACOB, W.F., CHIANG, Y.W., & LOTZE, M.T. (1994). LOCAL IL-4 DELIVERY ENHANCES IMMUNE REACTIVITY TO MURINE TUMORS - GENE-THERAPY IN COMBINATION WITH IL-2. CANCER GENE THERAPY, 1(1), 35-42.

POCKAJ, B.A., YANG, J.C., LOTZE, M.T., LANGE, J.R., SPENCER, W.F., STEINBERG, S.M., TOPALIAN, S.L., SCHWARTZENTRUBER, D.J., WHITE, D.E., & ROSENBERG, S.A. (1994). A PROSPECTIVE RANDOMIZED TRIAL EVALUATING COLLOID VERSUS CRYSTALLOID RESUSCITATION IN THE TREATMENT OF THE VASCULAR LEAK SYNDROME-ASSOCIATED INTERLEUKIN-2 THERAPY. JOURNAL OF IMMUNOTHERAPY, 15(1), 22-28.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-199401000-00003.

ROBBINS, P.D., TAHARA, H., MUELLER, G., HUNG, G., BAHNSON, A., ZITVOGEL, L., GALEALAURI, J., OHASHI, T., PATRENE, K., BOGGS, S.S., EVANS, C.H., BARRANGER, J.A., & LOTZE, M.T. (1994). RETROVIRAL VECTORS FOR USE IN HUMAN GENE-THERAPY FOR CANCER GAUCHER DISEASE, AND ARTHRITIS. GENE THERAPY FOR NEOPLASTIC DISEASES, 716(1), 72-89.Wiley. doi: 10.1111/j.1749-6632.1994.tb21704.x.

SCHWARZ, R.E., REYNOLDS, J.C., & LOTZE, M.T. (1994). PSEUDO-PSEUDOTUMOR OF THE LIVER - ADENOCARCINOMA PRESENTING AS AN INFLAMMATORY PSEUDOTUMOR. DIGESTIVE DISEASES AND SCIENCES, 39(12), 2679-2684.Springer Science and Business Media LLC. doi: 10.1007/BF02087709.

STRUMPH, P.S., CARTY, S.E., RILO, H.L.R., CARROLL, P.B., RICORDI, C., & LOTZE, M.T. (1994). INTERLEUKIN-1 RECEPTOR ANTAGONIST IS NOT DETRIMENTAL TO HUMAN ISLET-CELL INSULIN-SECRETION BUT DECREASES INSULIN CONTENT. TRANSPLANTATION PROCEEDINGS, 26(2), 694.

STUBER, G., LEDER, G.H., STORKUS, W.J., LOTZE, M.T., MODROW, S., SZEKELY, L., WOLF, H., KLEIN, E., KARRE, K., & KLEIN, G. (1994). IDENTIFICATION OF WILD-TYPE AND MUTANT P53 PEPTIDES BINDING TO HLA-A2 ASSESSED BY A PEPTIDE LOADING-DEFICIENT CELL-LINE ASSAY AND A NOVEL MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I PEPTIDE BINDING ASSAY. EUROPEAN JOURNAL OF IMMUNOLOGY, 24(3), 765-768.Wiley. doi: 10.1002/eji.1830240341.

TAHARA, H., ZEH, H.J., STORKUS, W.J., PAPPO, I., WATKINS, S.C., GUBLER, U., WOLF, S.F., ROBBINS, P.D., & LOTZE, M.T. (1994). FIBROBLASTS GENETICALLY-ENGINEERED TO SECRETE INTERLEUKIN-12 CAN SUPPRESS TUMOR-GROWTH AND INDUCE ANTITUMOR IMMUNITY TO A MURINE MELANOMA IN-VIVO. CANCER RESEARCH, 54(1), 182-189.

ZEH, H.J., LEDER, G.H., LOTZE, M.T., SALTER, R.D., TECTOR, M., STUBER, G., MODROW, S., & STORKUS, W.J. (1994). FLOW-CYTOMETRIC DETERMINATION OF PEPTIDE CLASS-I COMPLEX-FORMATION - IDENTIFICATION OF P53 PEPTIDES THAT BIND TO HLA-A2. HUMAN IMMUNOLOGY, 39(2), 79-86.Elsevier BV. doi: 10.1016/0198-8859(94)90105-8.

ZITVOGEL, L., TAHARA, H., CAI, Q., STORKUS, W.J., MULLER, G., WOLF, S.F., GATELY, M., ROBBINS, P.D., & LOTZE, M.T. (1994). CONSTRUCTION AND CHARACTERIZATION OF RETROVIRAL VECTORS EXPRESSING BIOLOGICALLY-ACTIVE HUMAN INTERLEUKIN-12. HUMAN GENE THERAPY, 5(12), 1493-1506.Mary Ann Liebert Inc. doi: 10.1089/hum.1994.5.12-1493.

HUNT, J.D., PIPPIN, B.A., LANDRENEAU, R.J., JACOB, W.F., LOTZE, M.T., & SIEGFRIED, J.M. (1993). TRANSFER AND EXPRESSION OF THE HUMAN INTERLEUKIN-4 GENE IN CARCINOMA AND STROMAL CELL-LINES DERIVED FROM LUNG-CANCER PATIENTS. JOURNAL OF IMMUNOTHERAPY, 14(4), 314-321.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-199311000-00011.

KAWAKAMI, Y., HAAS, G.P., & LOTZE, M.T. (1993). EXPANSION OF TUMOR-INFILTRATING LYMPHOCYTES FROM HUMAN TUMORS USING THE T-CELL GROWTH-FACTORS INTERLEUKIN-2 AND INTERLEUKIN-4. JOURNAL OF IMMUNOTHERAPY, 14(4), 336-347.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-199311000-00014.

LOTZE, M.T. (1993). TRANSPLANTATION AND ADOPTIVE CELLULAR THERAPY OF CANCER - THE ROLE OF T-CELL GROWTH-FACTORS. CELL TRANSPLANTATION, 2(1), 33-47.SAGE Publications. doi: 10.1177/096368979300200106.

Lotze, M.T., & Finn, O.J. (1993). Introduction: Report on the keystone symposium: Cellular immunity and the immunotherapy of cancer II. Journal of Immunotherapy, 14(2), 79-87. doi: 10.1097/00002371-199308000-00001.

MILLER, D.L., & LOTZE, M.T. (1993). A PLEA FOR A STANDARD STANDARD. RADIOLOGY, 188(1), 19-20.Radiological Society of North America (RSNA). doi: 10.1148/radiology.188.1.8390068.

Rosenberg, S.A., Lotze, M.T., & Yang, J.C. (1993). Erratum: Prospective randomized trial of high-dose interleukin-2 alone or in conjunction with lymphokine-activated killer cells for the treatment of patients with advanced cancer (J Natl Cancer Inst (1993) 85 (622-632)). Journal of the National Cancer Institute, 85(13), 1091.

ROSENBERG, S.A., LOTZE, M.T., YANG, J.C., TOPALIAN, S.L., CHANG, A.E., SCHWARTZENTRUBER, D.J., AEBERSOLD, P., LEITMAN, S., LINEHAN, W.M., SEIPP, C.A., WHITE, D.E., & STEINBERG, S.M. (1993). PROSPECTIVE RANDOMIZED TRIAL OF HIGH-DOSE INTERLEUKIN-2 ALONE OR IN CONJUNCTION WITH LYMPHOKINE-ACTIVATED KILLER-CELLS FOR THE TREATMENT OF PATIENTS WITH ADVANCED CANCER. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 85(8), 622-632.Oxford University Press (OUP). doi: 10.1093/jnci/85.8.622.

STORKUS, W.J., ZEH, H.J., MAEURER, M.J., SALTER, R.D., & LOTZE, M.T. (1993). IDENTIFICATION OF HUMAN-MELANOMA PEPTIDES RECOGNIZED BY CLASS-I RESTRICTED TUMOR-INFILTRATING T-LYMPHOCYTES. JOURNAL OF IMMUNOLOGY, 151(7), 3719-3727.

STORKUS, W.J., ZEH, H.J., SALTER, R.D., & LOTZE, M.T. (1993). IDENTIFICATION OF T-CELL EPITOPES - RAPID ISOLATION OF CLASS-I - PRESENTED PEPTIDES FROM VIABLE CELLS BY MILD ACID ELUTION. JOURNAL OF IMMUNOTHERAPY, 14(2), 94-103.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-199308000-00003.

WEIDMANN, E., ELDER, E.M., TRUCCO, M., LOTZE, M.T., & WHITESIDE, T.L. (1993). USAGE OF T-CELL RECEPTOR V-BETA CHAIN GENES IN FRESH AND CULTURED TUMOR-INFILTRATING LYMPHOCYTES FROM HUMAN-MELANOMA. INTERNATIONAL JOURNAL OF CANCER, 54(3), 383-390.Wiley. doi: 10.1002/ijc.2910540306.

WONG, H.L., COSTA, G.L., LOTZE, M.T., & WAHL, S.M. (1993). INTERLEUKIN (IL)-4 DIFFERENTIALLY REGULATES MONOCYTE IL-1 FAMILY GENE-EXPRESSION AND SYNTHESIS INVITRO AND INVIVO. JOURNAL OF EXPERIMENTAL MEDICINE, 177(3), 775-781.Rockefeller University Press. doi: 10.1084/jem.177.3.775.

ZEH, H.J., HURD, S., STORKUS, W.J., & LOTZE, M.T. (1993). INTERLEUKIN-12 PROMOTES THE PROLIFERATION AND CYTOLYTIC MATURATION OF IMMUNE EFFECTORS - IMPLICATIONS FOR THE IMMUNOTHERAPY OF CANCER. JOURNAL OF IMMUNOTHERAPY, 14(2), 155-161.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-199308000-00012.

CHOYKE, P.L., MILLER, D.L., LOTZE, M.T., WHITEIS, J.M., EBBITT, B., & ROSENBERG, S.A. (1992). DELAYED-REACTIONS TO CONTRAST-MEDIA AFTER INTERLEUKIN-2 IMMUNOTHERAPY. RADIOLOGY, 183(1), 111-114.Radiological Society of North America (RSNA). doi: 10.1148/radiology.183.1.1549655.

EMERY, B.E., WHITE, M.V., IGARASHI, Y., MULLOL, J., BERKEBILE, C., PEDEN, D., LOTZE, M.T., & KALINER, M.A. (1992). THE EFFECT OF IL-4 ON HUMAN NASAL MUCOSAL RESPONSES. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 90(5), 772-781.Elsevier BV. doi: 10.1016/0091-6749(92)90101-7.

LANGE, J.R., RAUBITSCHEK, A.A., POCKAJ, B.A., SPENCER, W.F., LOTZE, M.T., TOPALIAN, S.L., YANG, J.C., & ROSENBERG, S.A. (1992). A PILOT-STUDY OF THE COMBINATION OF INTERLEUKIN-2-BASED IMMUNOTHERAPY AND RADIATION-THERAPY. JOURNAL OF IMMUNOTHERAPY, 12(4), 265-271.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-199211000-00007.

LOTZE, M.T. (1992). PAPERS FROM THE 1992 KEYSTONE SYMPOSIUM ON MELANOMA AND BIOLOGY OF THE NEURAL CREST - INTRODUCTION. JOURNAL OF IMMUNOTHERAPY, 12(3), 153.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-199210000-00001.

Lotze, M.T., Rubin, J.T., & Zeh, H.J. (1992). New biologic agents come to bat for cancer therapy. Curr Opin Oncol, 4(6), 1116-1123.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00001622-199212000-00017.

Lotze, M.T., Zeh, H.J., Elder, E.M., Cai, Q., Pippin, B.A., Rosenstein, M.M., Whiteside, T.L., & Herberman, R. (1992). Use of T-cell growth factors (interleukins 2, 4, 7, 10, and 12) in the evaluation of T-cell reactivity to melanoma. J Immunother (1991), 12(3), 212-217.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00002371-199210000-00015.

MARINCOLA, F.M., VENZON, D., WHITE, D., RUBIN, J.T., LOTZE, M.T., SIMONIS, T.B., BALKISSOON, J., ROSENBERG, S.A., & PARKINSON, D.R. (1992). HLA ASSOCIATION WITH RESPONSE AND TOXICITY IN MELANOMA PATIENTS TREATED WITH INTERLEUKIN 2-BASED IMMUNOTHERAPY. CANCER RESEARCH, 52(23), 6561-6566.

RUBIN, J.T., & LOTZE, M.T. (1992). IMMUNE FUNCTION AND DYSFUNCTION - A PRIMER FOR THE RADIOLOGIST. RADIOLOGIC CLINICS OF NORTH AMERICA, 30(3), 507-523.

RUBIN, J.T., & LOTZE, M.T. (1992). ACUTE GASTRIC-MUCOSAL INJURY ASSOCIATED WITH THE SYSTEMIC ADMINISTRATION OF INTERLEUKIN-4. SURGERY, 111(3), 274-280.

SANDA, M.G., YANG, J.C., TOPALIAN, S.L., GROVES, E.S., CHILDS, A., BELFORT, R., DESMET, M.D., SCHWARTZENTRUBER, D.J., WHITE, D.E., LOTZE, M.T., & ROSENBERG, S.A. (1992). INTRAVENOUS ADMINISTRATION OF RECOMBINANT HUMAN MACROPHAGE COLONY-STIMULATING FACTOR TO PATIENTS WITH METASTATIC CANCER - A PHASE-I STUDY. JOURNAL OF CLINICAL ONCOLOGY, 10(10), 1643-1649.American Society of Clinical Oncology (ASCO). doi: 10.1200/JCO.1992.10.10.1643.

SPENCER, W.F., LINEHAN, W.M., WALTHER, M.M., HAAS, G.P., LOTZE, M.T., TOPALIAN, S.L., YANG, J.C., MERINO, M.J., LANGE, J.R., POCKAJ, B.A., & ROSENBERG, S.A. (1992). IMMUNOTHERAPY WITH INTERLEUKIN-2 AND ALPHA-INTERFERON IN PATIENTS WITH METASTATIC RENAL-CELL CANCER WITH INSITU PRIMARY CANCERS - A PILOT-STUDY. JOURNAL OF UROLOGY, 147(1), 24-30.Ovid Technologies (Wolters Kluwer Health). doi: 10.1016/S0022-5347(17)37124-0.

TAHARA, H., MUELLER, G.M., RICORDI, C., ROBBINS, P.D., & LOTZE, M.T. (1992). ISLET CELL TRANSPLANTATION FACILITATED BY GENE-TRANSFER. TRANSPLANTATION PROCEEDINGS, 24(6), 2975-2976.

WHITE, M.V., IGARASHI, Y., EMERY, B.E., LOTZE, M.T., & KALINER, M.A. (1992). EFFECTS OF INVIVO ADMINISTRATION OF INTERLEUKIN-2 (IL-2) AND IL-4, ALONE AND IN COMBINATION, ON EXVIVO HUMAN BASOPHIL HISTAMINE-RELEASE. BLOOD, 79(6), 1491-1495.American Society of Hematology. doi: 10.1182/blood.V79.6.1491.bloodjournal7961491.

WONG, H.L., LOTZE, M.T., WAHL, L.M., & WAHL, S.M. (1992). ADMINISTRATION OF RECOMBINANT IL-4 TO HUMANS REGULATES GENE-EXPRESSION, PHENOTYPE, AND FUNCTION IN CIRCULATING MONOCYTES. JOURNAL OF IMMUNOLOGY, 148(7), 2118-2125.

Culver, K., Cornetta, K., Morgan, R., Morecki, S., Aebersold, P., Kasid, A., Lotze, M., Rosenberg, S.A., Anderson, W.F., & Blaese, R.M. (1991). Lymphocytes as cellular vehicles for gene therapy in mouse and man. Proc Natl Acad Sci U S A, 88(8), 3155-3159.Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.88.8.3155.

Lotze, M.T. (1991). Concerning repeat hepatic resections for colorectal metastases [4]. Surgery, 109(3 I), 347-348.

LOTZE, M.T. (1991). TRIALS AND TRIBULATIONS - THE COST OF DEVELOPING GENE THERAPIES. FASEB JOURNAL, 5(15), 3013-3014.Wiley. doi: 10.1096/fasebj.5.15.1743433.

STOTTER, H., & LOTZE, M.T. (1991). HUMAN LYMPHOKINE-ACTIVATED KILLER-CELL ACTIVITY - ROLE OF IL-2, IL-4, AND IL-7. ARCHIVES OF SURGERY, 126(12), 1525-1530.American Medical Association (AMA). doi: 10.1001/archsurg.1991.01410360099017.

STOTTER, H., CUSTER, M.C., BOLTON, E.S., GUEDEZ, L., & LOTZE, M.T. (1991). IL-7 INDUCES HUMAN LYMPHOKINE-ACTIVATED KILLER-CELL ACTIVITY AND IS REGULATED BY IL-4. JOURNAL OF IMMUNOLOGY, 146(1), 150-155.

BOCK, S.N., LEE, R.E., FISHER, B., RUBIN, J.T., SCHWARTZENTRUBER, D.J., WEI, J.P., CALLENDER, D.P.E., YANG, J.C., LOTZE, M.T., PIZZO, P.A., & ROSENBERG, S.A. (1990). A PROSPECTIVE RANDOMIZED TRIAL EVALUATING PROPHYLACTIC ANTIBIOTICS TO PREVENT TRIPLE-LUMEN CATHETER-RELATED SEPSIS IN PATIENTS TREATED WITH IMMUNOTHERAPY. JOURNAL OF CLINICAL ONCOLOGY, 8(1), 161-169.American Society of Clinical Oncology (ASCO). doi: 10.1200/JCO.1990.8.1.161.

CUSTER, M.C., & LOTZE, M.T. (1990). A BIOLOGIC ASSAY FOR IL-4 - RAPID FLUORESCENCE ASSAY FOR IL-4 DETECTION IN SUPERNATANTS AND SERUM. JOURNAL OF IMMUNOLOGICAL METHODS, 128(1), 109-117.Elsevier BV. doi: 10.1016/0022-1759(90)90469-C.

JABLONS, D., BOLTON, E., MERTINS, S., RUBIN, M., PIZZO, P., ROSENBERG, S.A., & LOTZE, M.T. (1990). IL-2-BASED IMMUNOTHERAPY ALTERS CIRCULATING NEUTROPHIL FC RECEPTOR EXPRESSION AND CHEMOTAXIS. JOURNAL OF IMMUNOLOGY, 144(9), 3630-3636.

Jablons, D.M., Donohue, R., Kawakami, Y., Young, J.D., & Lotze, M.T. (1990). Interleukin-3 induces proliferation but not lymphokine activated killer activity from human and murine mononuclear cells. Eur Cytokine Netw, 1(2), 91-98.

KASID, A., DIRECTOR, E.P., STOVROFF, M.C., LOTZE, M.T., & ROSENBERG, S.A. (1990). CYTOKINE REGULATION OF TUMOR NECROSIS FACTOR-ALPHA AND FACTOR-BETA (LYMPHOTOXIN)-MESSENGER RNA EXPRESSION IN HUMAN PERIPHERAL-BLOOD MONONUCLEAR-CELLS. CANCER RESEARCH, 50(16), 5072-5076.

KASID, A., MORECKI, S., AEBERSOLD, P., CORNETTA, K., CULVER, K., FREEMAN, S., DIRECTOR, E., LOTZE, M.T., BLAESE, R.M., ANDERSON, W.F., & ROSENBERG, S.A. (1990). HUMAN-GENE TRANSFER - CHARACTERIZATION OF HUMAN TUMOR-INFILTRATING LYMPHOCYTES AS VEHICLES FOR RETROVIRAL-MEDIATED GENE-TRANSFER IN MAN. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 87(1), 473-477.Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.87.1.473.

KRAGEL, A.H., TRAVIS, W.D., FEINBERG, L., PITTALUGA, S., STRIKER, L.M., ROBERTS, W.C., LOTZE, M.T., YANG, J.J., & ROSENBERG, S.A. (1990). PATHOLOGICAL FINDINGS ASSOCIATED WITH INTERLEUKIN-2-BASED IMMUNOTHERAPY FOR CANCER - A POSTMORTEM STUDY OF 19 PATIENTS. HUMAN PATHOLOGY, 21(5), 493-502.Elsevier BV. doi: 10.1016/0046-8177(90)90005-P.

LAUE, L., LOTZE, M.T., CHROUSOS, G.P., BARNES, K., LORIAUX, D.L., & FLEISHER, T.A. (1990). EFFECT OF CHRONIC TREATMENT WITH THE GLUCOCORTICOID ANTAGONIST RU-486 IN MAN - TOXICITY, IMMUNOLOGICAL, AND HORMONAL ASPECTS. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 71(6), 1474-1480.The Endocrine Society. doi: 10.1210/jcem-71-6-1474.

Lotze, M.T., & Finn, O.J. (1990). Recent advances in cellular immunology: implications for immunity to cancer. Immunology Today, 11(C), 190-193. doi: 10.1016/0167-5699(90)90079-o.

LOTZE, M.T., & FINN, O.J. (1990). RECENT ADVANCES IN CELLULAR IMMUNOLOGY - IMPLICATIONS FOR IMMUNITY TO CANCER. IMMUNOLOGY TODAY, 11(6), 190-193.Elsevier BV. doi: 10.1016/0167-5699(90)90079-O.

LOTZE, M.T., CUSTER, M.C., BOLTON, E.S., WIEBKE, E.A., KAWAKAMI, Y., & ROSENBERG, S.A. (1990). MECHANISMS OF IMMUNOLOGICAL ANTITUMOR THERAPY - LESSONS FROM THE LABORATORY AND CLINICAL-APPLICATIONS. HUMAN IMMUNOLOGY, 28(2), 198-207.Elsevier BV. doi: 10.1016/0198-8859(90)90020-P.

ROSENBERG, S.A., AEBERSOLD, P., CORNETTA, K., KASID, A., MORGAN, R.A., MOEN, R., KARSON, E.M., LOTZE, M.T., YANG, J.C., TOPALIAN, S.L., MERINO, M.J., CULVER, K., MILLER, A.D., BLAESE, R.M., & ANDERSON, W.F. (1990). GENE-TRANSFER INTO HUMANS - IMMUNOTHERAPY OF PATIENTS WITH ADVANCED MELANOMA, USING TUMOR-INFILTRATING LYMPHOCYTES MODIFIED BY RETROVIRAL GENE TRANSDUCTION. NEW ENGLAND JOURNAL OF MEDICINE, 323(9), 570-578.Massachusetts Medical Society. doi: 10.1056/NEJM199008303230904.

STOTTER, H., & LOTZE, M.T. (1990). CYTOLYTIC EFFECTOR-CELLS AGAINST HUMAN TUMORS - DISTINGUISHING PHENOTYPE AND FUNCTION. CANCER CELLS-A MONTHLY REVIEW, 2(2), 44-+.

WARD, B., MCGARVEY, C., & LOTZE, M.T. (1990). EXCELLENT SHOULDER FUNCTION IS ATTAINABLE AFTER PARTIAL OR TOTAL SCAPULECTOMY - ANALYSIS AT PROLONGED FOLLOW-UP. ARCHIVES OF SURGERY, 125(4), 537-542.American Medical Association (AMA). doi: 10.1001/archsurg.1990.01410160125024.

WIEBKE, E.A., CUSTER, M.C., ROSENBERG, S.A., & LOTZE, M.T. (1990). CYTOKINES ALTER TARGET-CELL SUSCEPTIBILITY TO LYSIS .1. EVALUATION OF NONMAJOR HISTOCOMPATIBILITY COMPLEX-RESTRICTED EFFECTORS REVEALS DIFFERENTIAL-EFFECTS ON NATURAL AND LYMPHOKINE-ACTIVATED KILLING. JOURNAL OF BIOLOGICAL RESPONSE MODIFIERS, 9(2), 113-126.

DELVECCHIO, S., REYNOLDS, J.C., CARRASQUILLO, J.A., BLASBERG, R.G., NEUMANN, R.D., LOTZE, M.T., BRYANT, G.J., FARKAS, R.J., & LARSON, S.M. (1989). LOCAL-DISTRIBUTION AND CONCENTRATION OF INTRAVENOUSLY INJECTED I-131 9.2.27 MONOCLONAL-ANTIBODY IN HUMAN-MALIGNANT MELANOMA. CANCER RESEARCH, 49(10), 2783-2789.

DENICOFF, K.D., DURKIN, T.M., LOTZE, M.T., QUINLAN, P.E., DAVIS, C.L., LISTWAK, S.J., ROSENBERG, S.A., & RUBINOW, D.R. (1989). THE NEURO-ENDOCRINE EFFECTS OF INTERLEUKIN-2 TREATMENT. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 69(2), 402-410.The Endocrine Society. doi: 10.1210/jcem-69-2-402.

FISHER, B., KEENAN, A.M., GARRA, B.S., STEINBERG, S.M., WHITE, D.E., DIBISCEGLIE, A.M., HOOFNAGLE, J.H., YOLLES, P., ROSENBERG, S.A., & LOTZE, M.T. (1989). INTERLEUKIN-2 INDUCES PROFOUND REVERSIBLE CHOLESTASIS - A DETAILED ANALYSIS IN TREATED CANCER-PATIENTS. JOURNAL OF CLINICAL ONCOLOGY, 7(12), 1852-1862.American Society of Clinical Oncology (ASCO). doi: 10.1200/JCO.1989.7.12.1852.

JABLONS, D.M., MCINTOSH, J.K., MULE, J.J., NORDAN, R.P., RUDIKOFF, S., & LOTZE, M.T. (1989). INDUCTION OF INTERFERON-BETA-2 INTERLEUKIN-6 (IL-6) BY CYTOKINE ADMINISTRATION AND DETECTION OF CIRCULATING INTERLEUKIN-6 IN THE TUMOR-BEARING STATE. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 557(1), 157-161.Wiley. doi: 10.1111/j.1749-6632.1989.tb24008.x.

Jablons, D.M., Mule, J.J., McIntosh, J.K., Sehgal, P.B., May, L.T., Huang, C.M., Rosenberg, S.A., & Lotze, M.T. (1989). IF-6/IFN-β2 as a circulating hormone: Induction by cytokine administration in humans. Journal of Immunology, 142(5), 1542-1547.

KAWAKAMI, Y., CUSTER, M.C., ROSENBERG, S.A., & LOTZE, M.T. (1989). IL-4 REGULATES IL-2 INDUCTION OF LYMPHOKINE-ACTIVATED KILLER ACTIVITY FROM HUMAN-LYMPHOCYTES. JOURNAL OF IMMUNOLOGY, 142(10), 3452-3461.

LEE, R.E., LOTZE, M.T., SKIBBER, J.M., TUCKER, E., BONOW, R.O., OGNIBENE, F.P., CARRASQUILLO, J.A., SHELHAMER, J.H., PARRILLO, J.E., & ROSENBERG, S.A. (1989). CARDIORESPIRATORY EFFECTS OF IMMUNOTHERAPY WITH INTERLEUKIN-2. JOURNAL OF CLINICAL ONCOLOGY, 7(1), 7-20.American Society of Clinical Oncology (ASCO). doi: 10.1200/JCO.1989.7.1.7.

Lotze, M. (1989). Disturbing homeostasis: recent results of ongoing immunotherapy trials at the NCI. Biotechnol Ther, 1(2), 125-162.

LOTZE, M.T. (1989). HIGH-OUTPUT CARDIAC-FAILURE IN MULTIPLE-MYELOMA. NEW ENGLAND JOURNAL OF MEDICINE, 320(21), 1419-1420.Massachusetts Medical Society. doi: 10.1056/NEJM198905253202116.

McIntosh, J.K., Jablons, D.M., Mulé, J.J., Nordan, R.P., Rudikoff, S., Lotze, M.T., & Rosenberg, S.A. (1989). In vivo induction of IL-6 by administration of exogenous cytokines and detection of de novo serum levels of IL-6 in tumor-bearing mice. J Immunol, 143(1), 162-167.

MCINTOSH, J.K., MULE, J.J., JABLONS, D.M., NORDAN, R.P., RUDIKOFF, S., LOTZE, M.T., & ROSENBERG, S.A. (1989). THE KINETICS OF INTERLEUKIN-6 INDUCTION BY THE SYSTEMIC ADMINISTRATION OF RHTNF-ALPHA IN MICE. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 557(1), 572-575.Wiley. doi: 10.1111/j.1749-6632.1989.tb24070.x.

ROSENBERG, S.A., LOTZE, M.T., YANG, J.C., AEBERSOLD, P.M., LINEHAN, W.M., SEIPP, C.A., & WHITE, D.E. (1989). EXPERIENCE WITH THE USE OF HIGH-DOSE INTERLEUKIN-2 IN THE TREATMENT OF 652 CANCER-PATIENTS. ANNALS OF SURGERY, 210(4), 474-485.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00000658-198910000-00008.

ROSENBERG, S.A., LOTZE, M.T., YANG, J.C., LINEHAN, W.M., SEIPP, C., CALABRO, S., KARP, S.E., SHERRY, R.M., STEINBERG, S., & WHITE, D.E. (1989). COMBINATION THERAPY WITH INTERLEUKIN-2 AND ALPHA-INTERFERON FOR THE TREATMENT OF PATIENTS WITH ADVANCED CANCER. JOURNAL OF CLINICAL ONCOLOGY, 7(12), 1863-1874.American Society of Clinical Oncology (ASCO). doi: 10.1200/JCO.1989.7.12.1863.

Rubin, J.T., Elwood, L.J., Rosenberg, S.A., & Lotze, M.T. (1989). Immunohistochemical correlates of response to recombinant interleukin-2-based immunotherapy in humans. Cancer Res, 49(24 Pt 1), 7086-7092.

Sakahara, H., Reynolds, J.C., Carrasquillo, J.A., Lora, M.E., Maloney, P.J., Lotze, M.T., Larson, S.M., & Neumann, R.D. (1989). In vitro complex formation and biodistribution of mouse antitumor monoclonal antibody in cancer patients. J Nucl Med, 30(8), 1311-1317.

STOTTER, H., WIEBKE, E.A., TOMITA, S., BELLDEGRUN, A., TOPALIAN, S., ROSENBERG, S.A., & LOTZE, M.T. (1989). CYTOKINES ALTER TARGET-CELL SUSCEPTIBILITY TO LYSIS .2. EVALUATION OF TUMOR INFILTRATING LYMPHOCYTES. JOURNAL OF IMMUNOLOGY, 142(5), 1767-1773.

BEGLEY, M.G., SHAWKER, T.H., ROBERTSON, C.N., BOCK, S.N., WEI, J.P., & LOTZE, M.T. (1988). FOURNIER GANGRENE - DIAGNOSIS WITH SCROTAL ULTRASOUND. RADIOLOGY, 169(2), 387-389.Radiological Society of North America (RSNA). doi: 10.1148/radiology.169.2.3051115.

CHANG, A.E., KINSELLA, T., GLATSTEIN, E., BAKER, A.R., SINDELAR, W.F., LOTZE, M.T., DANFORTH, D.N., SUGARBAKER, P.H., LACK, E.E., STEINBERG, S.M., WHITE, D.E., & ROSENBERG, S.A. (1988). ADJUVANT CHEMOTHERAPY FOR PATIENTS WITH HIGH-GRADE SOFT-TISSUE SARCOMAS OF THE EXTREMITY. JOURNAL OF CLINICAL ONCOLOGY, 6(9), 1491-1500.American Society of Clinical Oncology (ASCO). doi: 10.1200/JCO.1988.6.9.1491.

COTRAN, R.S., POBER, J.S., GIMBRONE, M.A., SPRINGER, T.A., WIEBKE, E.A., GASPARI, A.A., ROSENBERG, S.A., & LOTZE, M.T. (1988). ENDOTHELIAL ACTIVATION DURING INTERLEUKIN-2 IMMUNOTHERAPY - A POSSIBLE MECHANISM FOR THE VASCULAR LEAK SYNDROME. JOURNAL OF IMMUNOLOGY, 140(6), 1883-1888.

Di Bisceglie, A.M., Rustgi, V.K., Hoofnagle, J.H., Dusheiko, G.M., & Lotze, M.T. (1988). NIH conference. Hepatocellular carcinoma. Ann Intern Med, 108(3), 390-401. doi: 10.7326/0003-4819-108-3-390.

JABLONS, D.M., & LOTZE, M.T. (1988). DERIVATION OF CELLS WITH LYTIC ACTIVITY AGAINST FRESH AND CULTURED TUMORS FROM HUMAN-BONE MARROW. JOURNAL OF SURGICAL RESEARCH, 44(4), 404-416.Elsevier BV. doi: 10.1016/0022-4804(88)90183-7.

KAWAKAMI, Y., ROSENBERG, S.A., & LOTZE, M.T. (1988). INTERLEUKIN-4 PROMOTES THE GROWTH OF TUMOR-INFILTRATING LYMPHOCYTES CYTO-TOXIC FOR HUMAN AUTOLOGOUS MELANOMA. JOURNAL OF EXPERIMENTAL MEDICINE, 168(6), 2183-2191.Rockefeller University Press. doi: 10.1084/jem.168.6.2183.

Lee, R.E. (1988). Interleukin 2 and Psoriasis. Archives of Dermatology, 124(12), 1811.American Medical Association (AMA). doi: 10.1001/archderm.1988.01670120027005.

LOTZE, M.T., & ROSENBERG, S.A. (1988). THE IMMUNOLOGICAL TREATMENT OF CANCER. CA-A CANCER JOURNAL FOR CLINICIANS, 38(2), 68-94.Wiley. doi: 10.3322/canjclin.38.2.68.

LOTZE, M.T., ROSS, W.G., TOMITA, S., & CUSTER, M.C. (1988). CELLS INVADING TUMORS - STRATEGIES FOR THE IDENTIFICATION AND EXPANSION OF TUMOR REACTIVE LYMPHOCYTES. TRANSPLANTATION PROCEEDINGS, 20(2), 326-331.

Ognibene, F.P., Rosenberg, S.A., Lotze, M., Skibber, J., Parker, M.M., Shelhamer, J.H., & Parrillo, J.E. (1988). Interleukin-2 administration causes reversible hemodynamic changes and left ventricular dysfunction similar to those seen in septic shock. Chest, 94(4), 750-754.Elsevier BV. doi: 10.1378/chest.94.4.750.

RIZZONI, W.E., MILLER, K., RICK, M., & LOTZE, M.T. (1988). HEPARIN-INDUCED THROMBOCYTOPENIA AND THROMBOEMBOLISM IN THE POSTOPERATIVE PERIOD. SURGERY, 103(4), 470-476.

ROBERTS, K., & LOTZE, M.T. (1988). INTERLEUKIN-2 PROMOTES CONJUGATE FORMATION BY PURIFIED LAK PRECURSORS AND LYMPHOCYTES-T - EVALUATION OF CONJUGATES USING FLOW CYTOMETRIC TECHNIQUES. JOURNAL OF BIOLOGICAL RESPONSE MODIFIERS, 7(3), 249-266.

Rosenberg, S.A., Lotze, M.T., & Mulé, J.J. (1988). NIH conference. New approaches to the immunotherapy of cancer using interleukin-2. Ann Intern Med, 108(6), 853-864. doi: 10.7326/0003-4819-108-6-853.

ROSENBERG, S.A., PACKARD, B.S., AEBERSOLD, P.M., SOLOMON, D., TOPALIAN, S.L., TOY, S.T., SIMON, P., LOTZE, M.T., YANG, J.C., SEIPP, C.A., SIMPSON, C., CARTER, C., BOCK, S., SCHWARTZENTRUBER, D., WEI, J.P., & WHITE, D.E. (1988). USE OF TUMOR-INFILTRATING LYMPHOCYTES AND INTERLEUKIN-2 IN THE IMMUNOTHERAPY OF PATIENTS WITH METASTATIC MELANOMA - A PRELIMINARY-REPORT. NEW ENGLAND JOURNAL OF MEDICINE, 319(25), 1676-1680.Massachusetts Medical Society. doi: 10.1056/NEJM198812223192527.

Schwartzentruber, D., Lotze, M.T., & Rosenberg, S.A. (1988). Colonic perforation: An unusual complication of therapy with high‐dose lnterleukin‐2. Cancer, 62(11), 2350-2353. doi: 10.1002/1097-0142(19881201)62:11<2350::AID-CNCR2820621116>3.0.CO;2-S.

TOPALIAN, S.L., SOLOMON, D., AVIS, F.P., CHANG, A.E., FREERKSEN, D.L., LINEHAN, W.M., LOTZE, M.T., ROBERTSON, C.N., SEIPP, C.A., SIMON, P., SIMPSON, C.G., & ROSENBERG, S.A. (1988). IMMUNOTHERAPY OF PATIENTS WITH ADVANCED CANCER USING TUMOR-INFILTRATING LYMPHOCYTES AND RECOMBINANT INTERLEUKIN-2 - A PILOT-STUDY. JOURNAL OF CLINICAL ONCOLOGY, 6(5), 839-853.American Society of Clinical Oncology (ASCO). doi: 10.1200/JCO.1988.6.5.839.

WIEBKE, E.A., ROSENBERG, S.A., & LOTZE, M.T. (1988). ACUTE IMMUNOLOGICAL EFFECTS OF INTERLEUKIN-2 THERAPY IN CANCER-PATIENTS - DECREASED DELAYED-TYPE HYPERSENSITIVITY RESPONSE AND DECREASED PROLIFERATIVE RESPONSE TO SOLUBLE-ANTIGENS. JOURNAL OF CLINICAL ONCOLOGY, 6(9), 1440-1449.American Society of Clinical Oncology (ASCO). doi: 10.1200/JCO.1988.6.9.1440.

COHEN, P.J., LOTZE, M.T., ROBERTS, J.R., ROSENBERG, S.A., & JAFFE, E.S. (1987). THE IMMUNOPATHOLOGY OF SEQUENTIAL TUMOR-BIOPSIES IN PATIENTS TREATED WITH INTERLEUKIN-2 - CORRELATION OF RESPONSE WITH T-CELL INFILTRATION AND HLA-DR EXPRESSION. AMERICAN JOURNAL OF PATHOLOGY, 129(2), 208-216.

DENICOFF, K.D., RUBINOW, D.R., PAPA, M.Z., SIMPSON, C., SEIPP, C.A., LOTZE, M.T., CHANG, A.E., ROSENSTEIN, D., & ROSENBERG, S.A. (1987). THE NEUROPSYCHIATRIC EFFECTS OF TREATMENT WITH INTERLEUKIN-2 AND LYMPHOKINE-ACTIVATED KILLER-CELLS. ANNALS OF INTERNAL MEDICINE, 107(3), 293-300.American College of Physicians. doi: 10.7326/0003-4819-107-2-293.

EDINGTON, H.D.J., & LOTZE, M.T. (1987). V-Y CLOSURE FOR ABDOMINAL-WALL STOMAL REDUCTION. SURGERY GYNECOLOGY & OBSTETRICS, 164(4), 381-382.

Gaspari, A.A. (1987). Dermatologic Changes Associated With Interleukin 2 Administration. JAMA: The Journal of the American Medical Association, 258(12), 1624.American Medical Association (AMA). doi: 10.1001/jama.1987.03400120074028.

Lotze, M.T., & Rosenberg, S.A. (1987). In Reply. JAMA: The Journal of the American Medical Association, 257(13), 1730-1731. doi: 10.1001/jama.1987.03390130047019.

Lotze, M.T., Custer, M.C., Sharrow, S.O., Rubin, L.A., Nelson, D.L., & Rosenberg, S.A. (1987). In vivo administration of purified human interleukin-2 to patients with cancer: development of interleukin-2 receptor positive cells and circulating soluble interleukin-2 receptors following interleukin-2 administration. Cancer Res, 47(8), 2188-2195.

LOTZE, M.T., ROBERTS, K., CUSTER, M.C., SEGAL, D.A., & ROSENBERG, S.A. (1987). SPECIFIC BINDING AND LYSIS OF HUMAN-MELANOMA BY IL-2-ACTIVATED CELLS COATED WITH ANTI-T3 OR ANTI-FC RECEPTOR CROSS-LINKED TO ANTIMELANOMA ANTIBODY - A POSSIBLE APPROACH TO THE IMMUNOTHERAPY OF HUMAN-TUMORS. JOURNAL OF SURGICAL RESEARCH, 42(5), 580-589.Elsevier BV. doi: 10.1016/0022-4804(87)90036-9.

ROBERTS, K., LOTZE, M.T., & ROSENBERG, S.A. (1987). SEPARATION AND FUNCTIONAL-STUDIES OF THE HUMAN LYMPHOKINE-ACTIVATED KILLER-CELL. CANCER RESEARCH, 47(16), 4366-4371.

ROSENBERG, S.A., LOTZE, M.T., MUUL, L.M., CHANG, A.E., AVIS, F.P., LEITMAN, S., LINEHAN, W.M., ROBERTSON, C.N., LEE, R.E., RUBIN, J.T., SEIPP, C.A., SIMPSON, C.G., & WHITE, D.E. (1987). A PROGRESS REPORT ON THE TREATMENT OF 157 PATIENTS WITH ADVANCED CANCER USING LYMPHOKINE-ACTIVATED KILLER-CELLS AND INTERLEUKIN-2 OR HIGH-DOSE INTERLEUKIN-2 ALONE. NEW ENGLAND JOURNAL OF MEDICINE, 316(15), 889-897.Massachusetts Medical Society. doi: 10.1056/NEJM198704093161501.

SKIBBER, J.M., LOTZE, M.T., MUUL, L.M., UPPENKAMP, I.K., ROSS, W., & ROSENBERG, S.A. (1987). HUMAN LYMPHOKINE-ACTIVATED KILLER CELLS - FURTHER ISOLATION AND CHARACTERIZATION OF THE PRECURSOR AND EFFECTOR CELL. NATURAL IMMUNITY AND CELL GROWTH REGULATION, 6(6), 291-305.

SKIBBER, J.M., LOTZE, M.T., SEIPP, C.A., SALCEDO, R., & ROSENBERG, S.A. (1987). LIMB-SPARING SURGERY FOR SOFT-TISSUE SARCOMAS - WOUND RELATED MORBIDITY IN PATIENTS UNDERGOING WIDE LOCAL EXCISION. SURGERY, 102(3), 447-452.

SKIBBER, J.M., LOTZE, M.T., UPPENKAMP, I., ROSS, W., & ROSENBERG, S.A. (1987). IDENTIFICATION AND EXPANSION OF HUMAN LYMPHOKINE-ACTIVATED KILLER-CELLS - IMPLICATIONS FOR THE IMMUNOTHERAPY OF CANCER. JOURNAL OF SURGICAL RESEARCH, 42(6), 613-621.Elsevier BV. doi: 10.1016/0022-4804(87)90004-7.

Skibber, J.M., Matter, G.J., Pizzo, P.A., & Lotze, M.T. (1987). Right lower quadrant pain in young patients with leukemia. Annals of Surgery, 206(6), 711-716. doi: 10.1097/00000658-198712000-00005.

VETTO, J.T., PAPA, M.Z., LOTZE, M.T., CHANG, A.E., & ROSENBERG, S.A. (1987). REDUCTION OF TOXICITY OF INTERLEUKIN-2 AND LYMPHOKINE-ACTIVATED KILLER-CELLS IN HUMANS BY THE ADMINISTRATION OF CORTICOSTEROIDS. JOURNAL OF CLINICAL ONCOLOGY, 5(3), 496-503.American Society of Clinical Oncology (ASCO). doi: 10.1200/JCO.1987.5.3.496.

Wiebke, E.A., Lotze, M.T., & Rosenberg, S.A. (1987). Tumor cell susceptibility to lysis: Marked increase in lysis by tumor-infiltrating lymphocytes following target stimulation with interferon-γ and tumor necrosis factor-α - Implications for immunotherapy. Surgical Forum, 38, 436-438.

Lotze, M.T. (1986). Surgical considerations in the diagnosis and management of AIDS. AIDS Res, 2(2), 141-148.Mary Ann Liebert Inc. doi: 10.1089/aid.1.1986.2.141.

Lotze, M.T. (1986). High-Dose Recombinant Interleukin 2 in the Treatment of Patients With Disseminated Cancer. JAMA, 256(22), 3117.American Medical Association (AMA). doi: 10.1001/jama.1986.03380220083027.

LOTZE, M.T., & ROSENBERG, S.A. (1986). RESULTS OF CLINICAL-TRIALS WITH THE ADMINISTRATION OF INTERLEUKIN-2 AND ADOPTIVE IMMUNOTHERAPY WITH ACTIVATED CELLS IN PATIENTS WITH CANCER. IMMUNOBIOLOGY, 172(3-5), 420-437.Elsevier BV. doi: 10.1016/S0171-2985(86)80122-X.

LOTZE, M.T., & ROSENBERG, S.A. (1986). PROTOCOL DESIGN FOR LYMPHOKINE TESTING IN CLINICAL-STUDIES OF HUMAN CANCER. LYMPHOKINE RESEARCH, 5(SUPPL. 1), S177-S181.

LOTZE, M.T., CARRASQUILLO, J.A., WEINSTEIN, J.N., BRYANT, G.J., PERENTESIS, P., REYNOLDS, J.C., MATIS, L.A., EGER, R.R., KEENAN, A.M., HELLSTROM, I., HELLSTROM, K.E., & LARSON, S.M. (1986). MONOCLONAL-ANTIBODY IMAGING OF HUMAN-MELANOMA - RADIOIMMUNODETECTION BY SUBCUTANEOUS OR SYSTEMIC INJECTION. ANNALS OF SURGERY, 204(3), 223-235.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00000658-198609000-00002.

LOTZE, M.T., CHANG, A.E., SEIPP, C.A., SIMPSON, C., VETTO, J.T., & ROSENBERG, S.A. (1986). HIGH-DOSE RECOMBINANT INTERLEUKIN-2 IN THE TREATMENT OF PATIENTS WITH DISSEMINATED CANCER - RESPONSES, TREATMENT-RELATED MORBIDITY, AND HISTOLOGIC-FINDINGS. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 256(22), 3117-3124.American Medical Association (AMA). doi: 10.1001/jama.256.22.3117.

LOTZE, M.T., CUSTER, M.C., & ROSENBERG, S.A. (1986). INTRAPERITONEAL ADMINISTRATION OF INTERLEUKIN-2 IN PATIENTS WITH CANCER. ARCHIVES OF SURGERY, 121(12), 1373-1379.American Medical Association (AMA). doi: 10.1001/archsurg.1986.01400120019002.

Lotze, M.T., Matory, Y.L., Rayner, A.A., Ettinghausen, S.E., Vetto, J.T., Seipp, C.A., & Rosenberg, S.A. (1986). Clinical effects and toxicity of interleukin‐2 in patients with cancer. Cancer, 58(12), 2764-2772. doi: 10.1002/1097-0142(19861215)58:12<2764::AID-CNCR2820581235>3.0.CO;2-Z.

PEREZ, P., TITUS, J.A., LOTZE, M.T., CUTTITTA, F., LONGO, D.L., GROVES, E.S., RABIN, H., DURDA, P.J., & SEGAL, D.M. (1986). SPECIFIC LYSIS OF HUMAN-TUMOR CELLS BY T-CELLS COATED WITH ANTI-T3 CROSS-LINKED TO ANTITUMOR ANTIBODY. JOURNAL OF IMMUNOLOGY, 137(7), 2069-2072.

Rosenberg, S.A., & Lotze, M.T. (1986). Cancer immunotherapy using interleukin-2 and interleukin-2-activated lymphocytes. Annu Rev Immunol, 4(1), 681-709.Annual Reviews. doi: 10.1146/annurev.iy.04.040186.003341.

ROSENBERG, S.A., LOTZE, M.T., MUUL, L.M., LEITMAN, S., CHANG, A.E., VETTO, J.T., SEIPP, C.A., & SIMPSON, C. (1986). A NEW APPROACH TO THE THERAPY OF CANCER BASED ON THE SYSTEMIC ADMINISTRATION OF AUTOLOGOUS LYMPHOKINE-ACTIVATED KILLER-CELLS AND RECOMBINANT INTERLEUKIN-2. SURGERY, 100(2), 262-272.

SKIBBER, J.M., LOTZE, M.T., GARRA, B., & FAUCI, A. (1986). SUCCESSFUL MANAGEMENT OF HEPATIC-ABSCESSES BY PERCUTANEOUS CATHETER DRAINAGE IN CHRONIC GRANULOMATOUS-DISEASE. SURGERY, 99(5), 626-629.

Chang, A.E., Lotze, M.T., Ames, R.S., Roth, J.A., & Rosenberg, S.A. (1985). A large scale method of separating multiple lymphokines secreted by the murine EL-4 thymoma. Journal of Immunopharmacology, 7(1), 17-31.

CHANG, A.E., LOTZE, M.T., AMES, R.S., ROTH, J.A., & ROSENBERG, S.A. (1985). A LARGE-SCALE METHOD OF SEPARATING MULTIPLE LYMPHOKINES SECRETED BY THE MURINE EL-4 THYMOMA. JOURNAL OF IMMUNOPHARMACOLOGY, 7(1), 17-31.Informa UK Limited. doi: 10.3109/08923978509026466.

LOTZE, M.T., & SUGARBAKER, P.H. (1985). FEMORAL-ARTERY BASED MYOCUTANEOUS FLAP FOR HEMIPELVECTOMY CLOSURE - AMPUTATION AFTER FAILED LIMB-SPARING SURGERY AND RADIOTHERAPY. AMERICAN JOURNAL OF SURGERY, 150(5), 625-629.Elsevier BV. doi: 10.1016/0002-9610(85)90451-9.

Lotze, M.T., Frana, L.W., Sharrow, S.O., Robb, R.J., & Rosenberg, S.A. (1985). In vivo administration of purified human interleukin 2. I. Half-life and immunologic effects of the Jurkat cell line-derived interleukin 2. J Immunol, 134(1), 157-166.

Lotze, M.T., Matory, Y.L., Ettinghausen, S.E., Rayner, A.A., Sharrow, S.O., Seipp, C.A., Custer, M.C., & Rosenberg, S.A. (1985). In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2. J Immunol, 135(4), 2865-2875.

Lotze, M.T., Rayner, A.A., & Grimm, E.A. (1985). Problems with the isolation of lymphoid clones with reactivity to human tumors. Behring Inst Mitt, (77), 105-114.

Rayner, A.A., Grimm, E.A., Lotze, M.T., Chu, E.W., & Rosenberg, S.A. (1985). Lymphokine‐activated killer (LAK) cells. Analysis of factors relevant to the immunotherapy of human cancer. Cancer, 55(6), 1327-1333. doi: 10.1002/1097-0142(19850315)55:6<1327::AID-CNCR2820550628>3.0.CO;2-O.

RAYNER, A.A., GRIMM, E.A., LOTZE, M.T., WILSON, D.J., & ROSENBERG, S.A. (1985). LYMPHOKINE-ACTIVATED KILLER (LAK) CELL PHENOMENON .4. LYSIS BY LAK CELL CLONES OF FRESH HUMAN-TUMOR CELLS FROM AUTOLOGOUS AND MULTIPLE ALLOGENEIC TUMORS. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 75(1), 67-75.

ROSENBERG, S.A., LOTZE, M.T., MUUL, L.M., LEITMAN, S., CHANG, A.E., ETTINGHAUSEN, S.E., MATORY, Y.L., SKIBBER, J.M., SHILONI, E., VETTO, J.T., SEIPP, C.A., SIMPSON, C., & REICHERT, C.M. (1985). OBSERVATIONS ON THE SYSTEMIC ADMINISTRATION OF AUTOLOGOUS LYMPHOKINE-ACTIVATED KILLER CELLS AND RECOMBINANT INTERLEUKIN-2 TO PATIENTS WITH METASTATIC CANCER. NEW ENGLAND JOURNAL OF MEDICINE, 313(23), 1485-1492.Massachusetts Medical Society. doi: 10.1056/NEJM198512053132327.

Donohue, J.H., Lotze, M.T., Robb, R.J., Rosenstein, M., Braziel, R.M., Jaffe, E.S., & Rosenberg, S.A. (1984). In vivo administration of purified Jurkat-derived interleukin 2 in mice. Cancer Res, 44(4), 1380-1386.

DONOHUE, J.H., ROSENSTEIN, M., CHANG, A.E., LOTZE, M.T., ROBB, R.J., & ROSENBERG, S.A. (1984). THE SYSTEMIC ADMINISTRATION OF PURIFIED INTERLEUKIN-2 ENHANCES THE ABILITY OF SENSITIZED MURINE LYMPHOCYTES TO CURE A DISSEMINATED SYNGENEIC LYMPHOMA. JOURNAL OF IMMUNOLOGY, 132(4), 2123-2128.

GRIMM, E.A., VOSE, B.M., CHU, E.W., WILSON, D.J., LOTZE, M.T., RAYNER, A.A., & ROSENBERG, S.A. (1984). THE HUMAN MIXED LYMPHOCYTE-TUMOR CELL-INTERACTION TEST .1. POSITIVE AUTOLOGOUS LYMPHOCYTE PROLIFERATIVE RESPONSES CAN BE STIMULATED BY TUMOR-CELLS AS WELL AS BY CELLS FROM NORMAL-TISSUES. CANCER IMMUNOLOGY IMMUNOTHERAPY, 17(2), 83-89.Springer Science and Business Media LLC. doi: 10.1007/BF00200041.

LONGO, D.L., STEIS, R.G., LANE, H.C., LOTZE, M.T., ROSENBERG, S.A., PREBLE, O., MASUR, H., ROOK, A.H., FAUCI, A.S., JACOB, J., & GELMANN, E.P. (1984). MALIGNANCIES IN THE AIDS PATIENT - NATURAL-HISTORY, TREATMENT STRATEGIES, AND PRELIMINARY-RESULTS. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 437(DEC), 421-430.Wiley. doi: 10.1111/j.1749-6632.1984.tb37163.x.

Lotze, M.T., & Rosenberg, S.A. (1984). In vivo use of cytokines. Clinical Immunology Newsletter, 5(8), 116-120.Elsevier BV. doi: 10.1016/s0197-1859(84)80031-x.

LOTZE, M.T., FRANA, L.W., SEIPP, C.A., SHARROW, S.O., & ROSENBERG, S.A. (1984). IMMUNOLOGICAL CHANGES IN PATIENTS WITH CANCER GIVEN INTERLEUKIN-2 (IL-2) IN A PHASE-I TRIAL. SURGICAL FORUM, 35, 407-408.

LOTZE, M.T., ROBB, R.J., SHARROW, S.O., FRANA, L.W., & ROSENBERG, S.A. (1984). SYSTEMIC ADMINISTRATION OF INTERLEUKIN-2 IN HUMANS. JOURNAL OF BIOLOGICAL RESPONSE MODIFIERS, 3(5), 475-482.

OURIEL, K., LOTZE, M.T., & HINSHAW, J.R. (1984). PROGNOSTIC FACTORS OF CARCINOMA OF THE MALE BREAST. SURGERY GYNECOLOGY & OBSTETRICS, 159(4), 373-376.

RAYNER, A.A., GRIMM, E.A., LOTZE, M.T., & ROSENBERG, S.A. (1984). DEMONSTRATION OF SHARED RECOGNITION AND LYSIS OF AUTOLOGOUS AND ALLOGENEIC FRESH HUMAN-TUMORS BY CLONED LYMPHOKINE-ACTIVATED KILLER CELLS. SURGICAL FORUM, 35, 415-417.

Harvey, J., Lotze, M., Arnett, F.C., Bias, W.B., Billingsley, L.M., Harvey, E., Hsu, S.H., Sutton, J.D., Zizic, T.M., & Stevens, M.B. (1983). Rheumatoid arthritis in a Chippewa band. II. Field study with clinical serologic and HLA-D correlations. J Rheumatol, 10(1), 28-32.

Lotze, M.T., Marquis, D.M., & Carey, A.S. (1983). Two new assays for the early detection of transplant rejection: IL-2 response and PHA-augmented NK activity. Transplantation Proceedings, 15(3), 1796-1799.

ROSENBERG, S.A., EBERLEIN, T.J., GRIMM, E.A., LOTZE, M.T., MAZUMDER, A., & ROSENSTEIN, M. (1982). DEVELOPMENT OF LONG-TERM CELL-LINES AND LYMPHOID CLONES REACTIVE AGAINST MURINE AND HUMAN-TUMORS - A NEW APPROACH TO THE ADOPTIVE IMMUNOTHERAPY OF CANCER. SURGERY, 92(2), 328-336.

BIAS, W.B., HSU, S.H., POLLARD, M.K., HARVEY, J., LOTZE, M.T., ARNETT, F.C., & STEVENS, M.B. (1981). HLA-DR CHARACTERIZATION OF A CHIPPEWA INDIAN SUB-POPULATION WITH HIGH PREVALENCE OF RHEUMATOID-ARTHRITIS. HUMAN IMMUNOLOGY, 2(2), 155-163.Elsevier BV. doi: 10.1016/0198-8859(81)90062-8.

Harvey, J., Lotze, M., Stevens, M.B., Lambert, G., & Jacobson, D. (1981). Rheumatoid arthritis in a Chippewa Band. I. Pilot screening study of disease prevalence. Arthritis Rheum, 24(5), 717-721.Wiley. doi: 10.1002/art.1780240515.

Lotze, M.T., & Rosenberg, S.A. (1981). In vitro growth of cytotoxic human lymphocytes. III. The preparation of lectin-free T cell growth factor (TCGF) and an analysis of its activity. J Immunol, 126(6), 2215-2220.

LOTZE, M.T., DUNCAN, M.A., GERBER, L.H., WOLTERING, E.A., & ROSENBERG, S.A. (1981). EARLY VERSUS DELAYED SHOULDER MOTION FOLLOWING AXILLARY DISSECTION - A RANDOMIZED PROSPECTIVE-STUDY. ANNALS OF SURGERY, 193(3), 288-295.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/00000658-198103000-00007.

Lotze, M.T., Grimm, E.A., Mazumder, A., Strausser, J.L., & Rosenberg, S.A. (1981). Lysis of fresh and cultured autologous tumor by human lymphocytes cultured in T-cell growth factor. Cancer Res, 41(11 Pt 1), 4420-4425.

STRAUSSER, J.L., MAZUMDER, A., GRIMM, E.A., LOTZE, M.T., & ROSENBERG, S.A. (1981). LYSIS OF HUMAN SOLID TUMORS BY AUTOLOGOUS CELLS SENSITIZED INVITRO TO ALLOANTIGENS. JOURNAL OF IMMUNOLOGY, 127(1), 266-271.

Lotze, M.T., Line, B.R., Mathisen, D.J., & Rosenberg, S.A. (1980). The in vivo distribution of autologous human and murine lymphoid cells grown in T cell growth factor (TCGF): implications for the adoptive immunotherapy of tumors. J Immunol, 125(4), 1487-1493.

Lotze, M.T., Strausser, J.L., & Rosenberg, S.A. (1980). In vitro growth of cytotoxic human lymphocytes. II. Use of T cell growth factor (TCGF) to clone human T cells. J Immunol, 124(6), 2972-2978.

LOTZE, M.T., STRAUSSER, J.L., LINE, B.R., & ROSENBERG, S.A. (1980). TUMOR LYSIS BY HUMAN LYMPHOCYTES-T IN LONG-TERM CULTURE AND THEIR DISTRIBUTION INVIVO - IMPLICATIONS FOR IMMUNOTHERAPY. SURGICAL FORUM, 31, 404-406.