headshot of William Federspiel

William Federspiel

John A Swanson Professor
Medical Devices Laboratory Bioengineering Department

about

(2019) Elected as National Academy of Inventors Fellow.

(2019) Appointed as John A. Swanson Professor.

(2019) 2019 Carnegie Science Award for Life Sciences.

(2018) Appointed to Editorial Board: Pediatric Research and Neonatal Care.

(2017) Appointed to Education Board, American Health Council.

(2016) Elected as an American Health Council Affiliate.

(2015) Invited by the Provost's and Chancellor's office to present my translational research experience to the University of Pittsburgh Board of Trustees in a talk entitled, "Respiratory Dialysis: A New Paradigm for Treating Lung Failure".

(2014) Certificate of Appreciation for Distinguished Service to the Rehabilitation Research and Development Service Scientific Merit Review Board from the Department of Veterans Affairs.

(2014) 2014 Carnegie Science Awards: Honorable Mention in the Start-Up Entrepreneur Award category.

(2014) Appointed to Honorary Editorial Board: Advanced Health Care Technologies.

(2014) ALung's Hemolung Respiratory Assist System (RAS) Recipient of Gold Award at Medical Design Excellence Awards.

(2013) Appointed to Editorial Board: Medical Instrumentation Journal.

(2011) Pitt Chronicle, featured in "Spotlight on Research: Charting the Future Through Bioengineering-Innovative ideas for lung disease and sepsis".

(2011) Member, American Institute for Medical Biological Engineering (AIMBE), Advocacy Committee.

(2011) Regular Member, Department of Veterans Affairs: Rehabilitation Research and Development Service.

(2010) Morning Journal, featured in "Emerging Technology May Help Patients Avoid Ventilators and Their Complications. Presented at: Morning Journal".

(2010) Top Ten MedGadget Award 2010: Alung's Hemolung Device.

(2009) Chair, Graduate Committee, Department of Bioengineering, University of Pittsburgh.

(2009 - 2013) Regular Member, NIH Study Section: Bioengineering, Technology and Surgical Sciences Study Section (BTSS).

(2008) Ad Hoc Member, NIH Study Section: Surgical Sciences, Biomedical Imaging and Bioengineering Integrated Review Group.

(2008) Appointed to Honorary Editorial Board: Medical Devices: Evidence and Research.

(2008) Chair, NIH Special Emphasis Review panel: Bioengineering Research Applications; Respiratory Sciences.

(2008) Appointed Member, International Scientific Advisory Committee for Biomed 2009.

(2007) New Scientist, featured in "A slimming treatment for artificial lungs".

(2007) Ad Hoc Member, NIH Study Section: Surgical Sciences, Biomedical Imaging and Bioengineering Integrated Review Group.

(2007) Elected Fellow, Biomedical Engineering Society (BMES).

(2007) Appointed to Editorial Board, Organogenesis.

(2006) Member, NIH Special Emphasis Panel: Bioengineering Research Applications: Respiratory.

(2006) Member, NIH Special Emphasis Panel: T1 Bioengineering Training Grants.

(2006) Member, NIH Special Emphasis Panel: BRP: Respiratory.

(2006) Member, NIH Special Emphasis Panel: Kidney Dialysis, Monitoring and Therapeutics.

(2006) Board of Visitors Award, School of Engineering, University Of Pittsburgh.

(2005) IEEE Spectrum, Profiled in story: "The Body Shops".

(2005) Appointed as William Kepler Whiteford Professor.

(2005) Ad Hoc Member, NIH Study Section, Vascular Cell and Molecular Biology.

(2005) Member, NIH Special Emphasis Review Panel: Bioengineering Research Applications: Respiratory Sciences.

(2004) Ad Hoc Member, NIH Study Section, Vascular Cell and Molecular Biology.

(2004) Appointed Section Editor, Bioengineering, ASAIO Journal.

(2003) World Technology Award for Health & Medicine, nominated.

(2003) Ad Hoc Member, NIH Study Section, Experimental Cardiovascular Services.

(2003 - 2005) Awarded CNG Faculty Fellowship, University of Pittsburgh.

(2002) Chemical and Engineering News, Profiled in story: "Pittsburgh Rising".

(2002) Invited Speaker: Pittsburgh Leadership Conference.

(2002) Ad Hoc Member, NIH Study Section, Experimental Cardiovascular Sciences.

(2002) Discover Magazine, featured in "100 top science stories of 2000".

(2001) New Scientist, featured in "Take a Breather".

(2001) USA Today, featured in "Artificial lung device holds breath of hope".

(2001) Ad Hoc Member, NIH Study Section, Surgery and Bioengineering.

(2001) Unrestricted Research Gift from Mallinckrodt Inc.: $25,000.

(2000) Ad Hoc Member, NIH Study Section, Lung Biology and Pathology.

(1999) Ad Hoc Member, NIH Study Section, Experimental Cardiovascular Sciences.

(1999) Ad Hoc Member, NIH Study Section, Surgery and Bioengineering.

(1999) Elected Fellow, American Institute for Medical and Biological Engineering.

(1998) Ad Hoc Member, NIH Study Section, Surgery and Bioengineering.

(1989) NIH Special Study Section Site Visit Team, RR01243, University of Washington.

(1986 - 1989) NIH New Investigator Research Award.

(1979 - 1982) NIH National Research Service Award.

(1978 - 1979) Shell Fellowship Award.

(1974 - 1978) Rochester Engineering Scholarship.

Ph.D., Chemical Engineering, University of Rochester, 1983

M.S., Chemical Engineering, University of Rochester, 1980

B.S., Chemical Engineering, University of Rochester, 1978

Ye, S.H., Orizondo, R.A., De, B.N., Kim, S., Frankowski, B.J., Federspiel, W.J., & Wagner, W.R. (2024). Epoxy silane sulfobetaine block copolymers for simple, aqueous thromboresistant coating on ambulatory assist lung devices. J Biomed Mater Res A, 112(1), 99-109.Wiley. doi: 10.1002/jbm.a.37619.

Omecinski, K.S., Frankowski, B.J., & Federspiel, W.J. (2023). Design and In Vitro Evaluation of an Artificial Placenta Made From Hollow Fiber Membranes. ASAIO J, 69(2), e86-e92.Wolters Kluwer. doi: 10.1097/MAT.0000000000001862.

Sanatkhani, S., Nedios, S., Menon, P.G., Saba, S.F., Jain, S.K., Federspiel, W.J., & Shroff, S.G. (2023). Subject-specific factors affecting particle residence time distribution of left atrial appendage in atrial fibrillation: A computational model-based study. Front Cardiovasc Med, 10, 1070498.Frontiers. doi: 10.3389/fcvm.2023.1070498.

Orizondo, R.A., Omecinski, K.S., May, A.G., Dhamotharan, V., Frankowski, B.J., Burgreen, G.W., Ye, S.H., Kocyildirim, E., Sanchez, P.G., D'Cunha, J., Wagner, W.R., & Federspiel, W.J. (2021). Month-long Respiratory Support by a Wearable Pumping Artificial Lung in an Ovine Model. Transplantation, 105(5), 999-1007.Wolters Kluwer. doi: 10.1097/TP.0000000000003481.

Cove, M.E., Vu, L.H., Ring, T., Federspiel, W.J., & Kellum, J.A. (2020). Respiratory Dialysis-A Novel Low Bicarbonate Dialysate to Provide Extracorporeal CO2 Removal. Crit Care Med, 48(7), e592-e598.Wolters Kluwer. doi: 10.1097/CCM.0000000000004351.

May, A.G., Omecinski, K.S., Frankowski, B.J., & Federspiel, W.J. (2020). Effect of Hematocrit on the CO2 Removal Rate of Artificial Lungs. ASAIO J, 66(10), 1161-1165.Wolters Kluwer. doi: 10.1097/MAT.0000000000001140.

May, A.G., Orizondo, R.A., Frankowski, B.J., Ye, S.H., Kocyildirim, E., Wagner, W.R., D'Cunha, J., & Federspiel, W.J. (2020). In vivo testing of the low-flow CO2 removal application of a compact, platform respiratory device. Intensive Care Med Exp, 8(1), 45.Springer Nature. doi: 10.1186/s40635-020-00329-9.

Cove, M.E., Vu, L.H., Ring, T., May, A.G., Federspiel, W.J., & Kellum, J.A. (2019). A Proof of Concept Study, Demonstrating Extracorporeal Carbon Dioxide Removal Using Hemodialysis with a Low Bicarbonate Dialysate. ASAIO J, 65(6), 605-613.Wolters Kluwer. doi: 10.1097/MAT.0000000000000879.

Madhani, S.P., Frankowski, B.J., Ye, S.H., Burgreen, G.W., Wagner, W.R., Kormos, R., D'Cunha, J., & Federspiel, W.J. (2019). In Vivo 5 Day Animal Studies of a Compact, Wearable Pumping Artificial Lung. ASAIO J, 65(1), 94-100.Wolters Kluwer. doi: 10.1097/MAT.0000000000000740.

May, A.G., Orizondo, R.A., Frankowski, B.J., Wearden, P.D., & Federspiel, W.J. (2019). Acute In Vivo Evaluation of the Pittsburgh Pediatric Ambulatory Lung. ASAIO J, 65(4), 395-400.Wolters Kluwer. doi: 10.1097/MAT.0000000000000918.

Vu, L.H., Kellum, J.A., Federspiel, W.J., & Cove, M.E. (2019). Carbon dioxide removal using low bicarbonate dialysis in rodents. Perfusion, 34(7), 578-583.SAGE Publications. doi: 10.1177/0267659119839284.

Harter, T.S., May, A.G., Federspiel, W.J., Supuran, C.T., & Brauner, C.J. (2018). Time course of red blood cell intracellular pH recovery following short-circuiting in relation to venous transit times in rainbow trout, Oncorhynchus mykiss. Am J Physiol Regul Integr Comp Physiol, 315(2), R397-R407.American Physiological Society. doi: 10.1152/ajpregu.00062.2018.

Malkin, A.D., Ye, S.H., Lee, E.J., Yang, X., Zhu, Y., Gamble, L.J., Federspiel, W.J., & Wagner, W.R. (2018). Development of zwitterionic sulfobetaine block copolymer conjugation strategies for reduced platelet deposition in respiratory assist devices. J Biomed Mater Res B Appl Biomater, 106(7), 2681-2692.Wiley. doi: 10.1002/jbm.b.34085.

May, A.G., Jeffries, R.G., Frankowski, B.J., Burgreen, G.W., & Federspiel, W.J. (2018). Bench Validation of a Compact Low-Flow CO2 Removal Device. Intensive Care Med Exp, 6(1), 34.Springer Nature. doi: 10.1186/s40635-018-0200-7.

Orizondo, R., Gino, G., Sultzbach, G., Madhani, S., Frankowski, B., & Federspiel, W. (2018). Effects of Hollow Fiber Membrane Oscillation on an Artificial Lung. Annals of Biomedical Engineering, 46(5), 762-771.Springer Verlag. doi: 10.1007/s10439-018-1995-9.

Orizondo, R.A., May, A.G., Madhani, S.P., Frankowski, B.J., Burgreen, G.W., Wearden, P.D., & Federspiel, W.J. (2018). In Vitro Characterization of the Pittsburgh Pediatric Ambulatory Lung. ASAIO J, 64(6), 806-811.Wolters Kluwer. doi: 10.1097/MAT.0000000000000711.

Jeffries, R.G., Lund, L., Frankowski, B., & Federspiel, W.J. (2017). An extracorporeal carbon dioxide removal (ECCO2R) device operating at hemodialysis blood flow rates. Intensive Care Med Exp, 5(1), 41.Springer Nature. doi: 10.1186/s40635-017-0154-1.

Madhani, S.P., Frankowski, B.J., & Federspiel, W.J. (2017). Fiber Bundle Design for an Integrated Wearable Artificial Lung. ASAIO J, 63(5), 631-636.Wolters Kluwer. doi: 10.1097/MAT.0000000000000542.

Madhani, S.P., Frankowski, B.J., Burgreen, G.W., Antaki, J.F., Kormos, R., D'Cunha, J., & Federspiel, W.J. (2017). In vitro and in vivo evaluation of a novel integrated wearable artificial lung. J Heart Lung Transplant, 36(7), 806-811.Elsevier. doi: 10.1016/j.healun.2017.02.025.

May, A.G., Sen, A., Cove, M.E., Kellum, J.A., & Federspiel, W.J. (2017). Extracorporeal CO2 removal by hemodialysis: in vitro model and feasibility. Intensive Care Med Exp, 5(1), 20.Springer Nature. doi: 10.1186/s40635-017-0132-7.

Madhani, S.P., D'Aloiso, B.D., Frankowski, B., & Federspiel, W.J. (2016). Darcy Permeability of Hollow Fiber Membrane Bundles Made from Membrana Polymethylpentene Fibers Used in Respiratory Assist Devices. ASAIO J, 62(3), 329-331.Wolters Kluwer. doi: 10.1097/MAT.0000000000000348.

Nguyen, J., Malkin, A., & Federspiel, W. (2016). New chemical methods developed on prototypes with hopes to improve gas exchange within respiratory devices. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 251.

Parker, R.S., Hogg, J.S., Roy, A., Kellum, J.A., Rimmelé, T., Daun-Gruhn, S., Fedorchak, M.V., Valenti, I.E., Federspiel, W.J., Rubin, J., Vodovotz, Y., Lagoa, C., & Clermont, G. (2016). Modeling and Hemofiltration Treatment of Acute Inflammation. Processes (Basel), 4(4), 38.MDPI. doi: 10.3390/pr4040038.

Arazawa, D.T., Kimmel, J.D., & Federspiel, W.J. (2015). Kinetics of CO2 exchange with carbonic anhydrase immobilized on fiber membranes in artificial lungs. J Mater Sci Mater Med, 26(6), 193.Springer Nature. doi: 10.1007/s10856-015-5525-0.

Arazawa, D.T., Kimmel, J.D., Finn, M.C., & Federspiel, W.J. (2015). Acidic sweep gas with carbonic anhydrase coated hollow fiber membranes synergistically accelerates CO2 removal from blood. Acta Biomaterialia, 25, 143-149.Elsevier. doi: 10.1doi:10.1016/j.actbio.2015.07.007016/j.actbio.2015.07.007.

Cook, K.E., Maul, T.M., & Federspiel, W.J. (2015). Artificial Lungs. In The Biomedical Engineering Handbook: Molecular, Cellular, and Tissue Engineering, Bronzino, J.D., & Peterson, D.R. (Eds.). (p. 78-1).CRC Press.

Cove, M.E., & Federspiel, W.J. (2015). Veno-venous extracorporeal CO2 removal for the treatment of severe respiratory acidosis. Crit Care, 19(1), 176.Springer Nature. doi: 10.1186/s13054-015-0769-0.

Madhani, S., & Federspiel, W.J. (2015). Letter to the Editor on: "Darcy permeability of hollow fiber bundles used in blood oxygenation devices" [J. Membr. Sci. 382 (2011) 238-242]. JOURNAL OF MEMBRANE SCIENCE, 496, 359-360.Elsevier. doi: 10.1016/j.memsci.2015.09.012.

Malkin, A.D., Sheehan, R.P., Mathew, S., Federspiel, W.J., Redl, H., & Clermont, G. (2015). A Neutrophil Phenotype Model for Extracorporeal Treatment of Sepsis. In Tan, K. (Ed.). PLoS Comput Biol, 11(10), e1004314.Public Library of Science (PLoS). doi: 10.1371/journal.pcbi.1004314.

Ye, S.H., Arazawa, D.T., Zhu, Y., Shankarraman, V., Malkin, A.D., Kimmel, J.D., Gamble, L.J., Ishihara, K., Federspiel, W.J., & Wagner, W.R. (2015). Hollow fiber membrane modification with functional zwitterionic macromolecules for improved thromboresistance in artificial lungs. Langmuir, 31(8), 2463-2471.American Chemical Society (ACS). doi: 10.1021/la504907m.

Zhang, J., Peng, Z., Maberry, D., Volpe, J., Kimmel, J.D., Federspiel, W.J., & Kellum, J.A. (2015). Effects of hemoadsorption with a novel adsorbent on sepsis: in vivo and in vitro study. Blood Purif, 39(1-3), 239-245.Karger Publishers. doi: 10.1159/000381006.

Jeffries, R.G., Frankowski, B.J., Burgreen, G.W., & Federspiel, W.J. (2014). Effect of impeller design and spacing on gas exchange in a percutaneous respiratory assist catheter. Artif Organs, 38(12), 1007-1017.Wiley. doi: 10.1111/aor.12308.

Jeffries, R.G., Mussin, Y., Bulanin, D.S., Lund, L.W., Kocyildirim, E., Zhumadilov, Z.Z., Olzhayev, F.S., Federspiel, W.J., & Wearden, P.D. (2014). Pre-clinical evaluation of an adult extracorporeal carbon dioxide removal system with active mixing for pediatric respiratory support. Int J Artif Organs, 37(12), 888-899.SAGE Publications. doi: 10.5301/ijao.5000372.

Mussin, Y., Jeffries, R., Bulanin, D., Zhumadilov, Z., Olzhayev, F., & Federspiel, W. (2014). Pre-clinical Evaluation of an Adult Extracoproreal Carbon Dioxide Removal System for Pediatric Application. Cent Asian J Glob Health, 3(Suppl), 167.University Library System, University of Pittsburgh. doi: 10.5195/cajgh.2014.167.

Peng, Z.Y., Bishop, J.V., Wen, X.Y., Elder, M.M., Zhou, F., Chuasuwan, A., Carter, M.J., Devlin, J.E., Kaynar, A.M., Singbartl, K., Pike, F., Parker, R.S., Clermont, G., Federspiel, W.J., & Kellum, J.A. (2014). Modulation of chemokine gradients by apheresis redirects leukocyte trafficking to different compartments during sepsis, studies in a rat model. Crit Care, 18(4), R141.Springer Nature. doi: 10.1186/cc13969.

Sen, A., Kellum, J., & Federspiel, W. (2014). EXTRACORPOREAL CARBON-DIOXIDE REMOVAL IS FEASIBLE USING A ZERO BICARBONATE DIALYSATE. CRITICAL CARE MEDICINE, 42, (p. a1521).Wolters Kluwer. doi: 10.1097/01.ccm.0000458168.22241.90.

Kimmel, J.D., Arazawa, D.T., Ye, S.H., Shankarraman, V., Wagner, W.R., & Federspiel, W.J. (2013). Carbonic anhydrase immobilized on hollow fiber membranes using glutaraldehyde activated chitosan for artificial lung applications. J Mater Sci Mater Med, 24(11), 2611-2621.Springer Nature. doi: 10.1007/s10856-013-5006-2.

Lund, L.W., & Federspiel, W.J. (2013). Removing extra CO2 in COPD patients. Curr Respir Care Rep, 2(3), 131-138.Springer Nature. doi: 10.1007/s13665-013-0057-x.

Rimmelé, T., Kaynar, A.M., McLaughlin, J.N., Bishop, J.V., Fedorchak, M.V., Chuasuwan, A., Peng, Z., Singbartl, K., Frederick, D.R., Zhu, L., Carter, M., Federspiel, W.J., Zeevi, A., & Kellum, J.A. (2013). Leukocyte capture and modulation of cell-mediated immunity during human sepsis: an ex vivo study. Crit Care, 17(2), R59.Springer Nature. doi: 10.1186/cc12587.

Sen, A., Kellum, J.A., & Federspiel, W.J. (2013). Extracorporeal Carbon Dioxide Removal By Zero Bicarbonate Dialysate: A Novel Lung Protection Strategy. Critical Care Medicine, 41, (p. A47).Wolters Kluwer. doi: 10.1097/01.ccm.0000439357.52072.a2.

Alikhani, A., & Federspiel, W.J. (2012). Selective capture of anti-A antibodies from human blood using a novel integrated bead and hollow fiber module. J Biomed Mater Res B Appl Biomater, 100(8), 2114-2121.Wiley. doi: 10.1002/jbm.b.32776.

Alikhani, A., & Federspiel, W.J. (2012). Selective capture of anti-A antibodies from human blood using a novel integrated bead and hollow fiber module. Journal of biomedical materials research. Part B, Applied biomaterials, 100(8), 2114-2121. doi: 10.1002/jbm.b.32776.

Arazawa, D.T., Oh, H.I., Ye, S.H., Johnson, C.A., Woolley, J.R., Wagner, W.R., & Federspiel, W.J. (2012). Immobilized Carbonic Anhydrase on Hollow Fiber Membranes Accelerates CO(2) Removal from Blood. J Memb Sci, 404-404, 25-31.Elsevier. doi: 10.1016/j.memsci.2012.02.006.

Cove, M., Sen, A., Federspiel, W., & Kellum, J. (2012). "RESPIRATORY DIALYSIS": A NOVEL APPROACH FOR ENABLING LUNG PROTECTIVE VENTILATION. CRITICAL CARE MEDICINE, 40, (p. U277).

Cove, M.E., MacLaren, G., Federspiel, W.J., & Kellum, J.A. (2012). Bench to bedside review: Extracorporeal carbon dioxide removal, past present and future. Crit Care, 16(5), 232.Springer Nature. doi: 10.1186/cc11356.

Federspiel, W.J., & Valenti, I. (2012). On Laminar Flow in Microfabricated Channels with Partial Semi-Circular Profiles. Open Journal of Applied Sciences, 02(01), 28-34.Scientific Research Publishing. doi: 10.4236/ojapps.2012.21003.

Fisher, J.D., DiLeo, M.V., & Federspiel, W.J. (2012). Investigating Cytokine Binding Using a Previously Reported TNF-Specific Aptamer. Open Journal of Applied Sciences, 02(03), 135-138.Scientific Research Publishing. doi: 10.4236/ojapps.2012.23019.

Namas, R.A., Namas, R., Lagoa, C., Barclay, D., Mi, Q., Zamora, R., Peng, Z., Wen, X., Fedorchak, M.V., Valenti, I.E., Federspiel, W.J., Kellum, J.A., & Vodovotz, Y. (2012). Hemoadsorption reprograms inflammation in experimental gram-negative septic peritonitis: insights from in vivo and in silico studies. Mol Med, 18(1), 1366-1374.Springer Nature. doi: 10.2119/molmed.2012.00106.

Peng, Z.Y., Wang, H.Z., Carter, M.J., Dileo, M.V., Bishop, J.V., Zhou, F.H., Wen, X.Y., Rimmelé, T., Singbartl, K., Federspiel, W.J., Clermont, G., & Kellum, J.A. (2012). Acute removal of common sepsis mediators does not explain the effects of extracorporeal blood purification in experimental sepsis. Kidney Int, 81(4), 363-369.Elsevier. doi: 10.1038/ki.2011.320.

Wearden, P.D., Federspiel, W.J., Morley, S.W., Rosenberg, M., Bieniek, P.D., Lund, L.W., & Ochs, B.D. (2012). Respiratory dialysis with an active-mixing extracorporeal carbon dioxide removal system in a chronic sheep study. Intensive Care Med, 38(10), 1705-1711.Springer Nature. doi: 10.1007/s00134-012-2651-8.

Alikhani, A., & Federspiel, W.J. (2011). Theoretical and experimental analysis of anti-A antibody capture in novel integrated bead and hollow fiber modules. Ann Biomed Eng, 39(3), 953-963.Springer Nature. doi: 10.1007/s10439-010-0233-x.

Batchinsky, A.I., Jordan, B.S., Regn, D., Necsoiu, C., Federspiel, W.J., Morris, M.J., & Cancio, L.C. (2011). Respiratory dialysis: reduction in dependence on mechanical ventilation by venovenous extracorporeal CO2 removal. Crit Care Med, 39(6), 1382-1387.Wolters Kluwer. doi: 10.1097/CCM.0b013e31820eda45.

DiLeo, M.V., Fisher, J.D., Burton, B.M., & Federspiel, W.J. (2011). Selective improvement of tumor necrosis factor capture in a cytokine hemoadsorption device using immobilized anti-tumor necrosis factor. J Biomed Mater Res B Appl Biomater, 96(1), 127-133.Wiley. doi: 10.1002/jbm.b.31748.

Kimmel, J.D., Harbert, E.M., Parker, R.S., & Federspiel, W.J. (2011). Modeling competitive cytokine adsorption dynamics within hemoadsorption beads used to treat sepsis. J Chromatogr A, 1218(44), 8013-8020.Elsevier. doi: 10.1016/j.chroma.2011.09.007.

Kimmel, J.D., Lacko, C.S., Delude, R.L., & Federspiel, W.J. (2011). Characterizing accelerated capture of deoligomerized TNF within hemoadsorption beads used to treat sepsis. J Biomed Mater Res B Appl Biomater, 98(1), 47-53.Wiley. doi: 10.1002/jbm.b.31830.

Kimmel, J.D., Lacko, C.S., Delude, R.L., & Federspiel, W.J. (2011). ACCELERATED REMOVAL OF TNF WITHIN A HEMOADSORPTION DEVICE USED TO TREAT SEPSIS. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, 34, (p. 640).

Pacella, H.E., Eash, H.J., & Federspiel, W.J. (2011). Darcy Permeability of Hollow Fiber Bundles Used in Blood Oxygenation Devices. J Memb Sci, 382(1-2), 238-242.Elsevier. doi: 10.1016/j.memsci.2011.08.012.

Burki, N.K., Bieniek, P.D., Federspiel, W., Morley, S.W., Ochs, B.D., & Wearden, P.D. (2010). Efficacy of Extracorporeal CO2 Removal with the Hemolung: Results in Animals. Am J Respir Crit Care Med, 181.

Dileo, M.V., & Federspiel, W.J. (2010). Scaling issues in the article entitled "cytokines in blood from septic patients interact with surface-immobilized heparin". ASAIO J, 56(4), 383-384.Wolters Kluwer. doi: 10.1097/MAT.0b013e3181e4bfc3.

Gautam, S., Korchagina, E.Y., Bovin, N.V., & Federspiel, W.J. (2010). Specific antibody filter (SAF) binding capacity enhancement to remove anti-A antibodies. J Biomed Mater Res B Appl Biomater, 95(2), 475-480.Wiley. doi: 10.1002/jbm.b.31707.

Kimmel, J.D., Gibson, G.A., Watkins, S.C., Kellum, J.A., & Federspiel, W.J. (2010). IL-6 adsorption dynamics in hemoadsorption beads studied using confocal laser scanning microscopy. J Biomed Mater Res B Appl Biomater, 92(2), 390-396.Wiley. doi: 10.1002/jbm.b.31527.

Kimmel, J.D., Lacko, C.S., Delude, R.L., & Federspiel, W.J. (2010). Dynamics of TNF capture within hemoadsorption beads used to treat sepsis. ASME 2010 Summer Bioengineering Conference, SBC 2010, (pp. 85-86).ASME International.Lake Tahoe, CA. doi: 10.1115/SBC2010-19242.

Oh, H.I., Ye, S.H., Johnson, C.A., Woolley, J.R., Federspiel, W.J., & Wagner, W.R. (2010). Hemocompatibility assessment of carbonic anhydrase modified hollow fiber membranes for artificial lungs. Artif Organs, 34(5), 439-442.Wiley. doi: 10.1111/j.1525-1594.2009.00882.x.

Polk, A.A., Maul, T.M., McKeel, D.T., Snyder, T.A., Lehocky, C.A., Pitt, B., Stolz, D.B., Federspiel, W.J., & Wagner, W.R. (2010). A biohybrid artificial lung prototype with active mixing of endothelialized microporous hollow fibers. Biotechnol Bioeng, 106(3), 490-500.Wiley. doi: 10.1002/bit.22675.

Alikhani, A., Korchagina, E.Y., Chinarev, A.A., Bovin, N.V., & Federspiel, W.J. (2009). High molecular weight blood group A trisaccharide-polyacrylamide glycoconjugates as synthetic blood group A antigens for anti-A antibody removal devices. J Biomed Mater Res B Appl Biomater, 91(2), 845-854.Wiley. doi: 10.1002/jbm.b.31466.

Budilarto, S.G., Frankowski, B.J., Hattler, B.G., & Federspiel, W.J. (2009). Flow visualization study of a novel respiratory assist catheter. Artif Organs, 33(6), 411-418.Wiley. doi: 10.1111/j.1525-1594.2009.00751.x.

Burgess, K.A., Hu, H.H., Wagner, W.R., & Federspiel, W.J. (2009). Towards microfabricated biohybrid artificial lung modules for chronic respiratory support. Biomed Microdevices, 11(1), 117-127.Springer Nature. doi: 10.1007/s10544-008-9215-2.

Burgess, K.A., Wagner, W.R., & Federspiel, W.J. (2009). TOWARDS BIOHYBRID MICROFABRICATED ARTIFICIAL LUNGS. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, 32, (p. 402).Compiegne, France.

DiLeo, M.V., Fisher, J.D., & Federspiel, W.J. (2009). Experimental validation of a theoretical model of cytokine capture using a hemoadsorption device. Ann Biomed Eng, 37(11), 2310-2316.Springer Nature. doi: 10.1007/s10439-009-9780-4.

DiLeo, M.V., Kellum, J.A., & Federspiel, W.J. (2009). A simple mathematical model of cytokine capture using a hemoadsorption device. Ann Biomed Eng, 37(1), 222-229.Springer Nature. doi: 10.1007/s10439-008-9587-8.

DiLeo, M.V., Kimmel, J.D., Kellum, J.A., & Federspiel, W.J. (2009). MODELING CYTOKINE CAPTURE IN A HEMOADSORPTION DEVICE FOR THE TREATMENT OF SEPSIS. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, 32, (p. 419).Compiegne, France.

Kimmel, J.D., DiLeo, M.V., Valenti, I.E., Gibson, G.A., Watkins, S.C., & Federspiel, W.J. (2009). Dynamics of cytokine capture within hemoadsorption beads used to treat sepsis. Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, (pp. 947-948).ASME International.Pittsburgh, PA. doi: 10.1115/SBC2009-204764.

Mihelc, K.M., Frankowski, B.J., Lieber, S.C., Moore, N.D., Hattler, B.G., & Federspiel, W.J. (2009). Evaluation of a respiratory assist catheter that uses an impeller within a hollow fiber membrane bundle. ASAIO J, 55(6), 569-574.Wolters Kluwer. doi: 10.1097/MAT.0b013e3181bc2655.

Rothstein, S.N., Federspiel, W.J., & Little, S.R. (2009). A unified mathematical model for the prediction of controlled release from surface and bulk eroding polymer matrices. Biomaterials, 30(8), 1657-1664.Elsevier. doi: 10.1016/j.biomaterials.2008.12.002.

Engelmayr, G.C., Soletti, L., Vigmostad, S.C., Budilarto, S.G., Federspiel, W.J., Chandran, K.B., Vorp, D.A., & Sacks, M.S. (2008). A novel flex-stretch-flow bioreactor for the study of engineered heart valve tissue mechanobiology. Ann Biomed Eng, 36(5), 700-712.Springer Nature. doi: 10.1007/s10439-008-9447-6.

Gautam, S., Korchagina, E.Y., Bovin, N.V., & Federspiel, W.J. (2008). Monoclonal anti-A antibody removal by synthetic A antigen immobilized on specific antibody filters. Biotechnol Bioeng, 99(4), 876-883.Wiley. doi: 10.1002/bit.21621.

Kimmel, J.D., & Federspiel, W. (2008). Cytokine Hemoadsorption Dynamics using Confocal Laser Scanning Microscopy. ASAIO Journal, 54, (p. 7A).

Morley, S., Rosenberg, M., Federspiel, W., Hattler, B.G., & Batchinsky, A. (2008). Respiratory Dialysis. A New Therapy for Chronic Obstructive Pulmonary Disease. Critical Care, 12, (p. P303).

Rothstein, S.N., Federspiel, W.J., & Little, S.R. (2008). A simple model framework for the prediction of controlled release from bulk eroding polymer matrices. JOURNAL OF MATERIALS CHEMISTRY, 18(16), 1873-1880.Royal Society of Chemistry (RSC). doi: 10.1039/b718277e.

Svitek, R.G., & Federspiel, W.J. (2008). A mathematical model to predict CO2 removal in hollow fiber membrane oxygenators. Ann Biomed Eng, 36(6), 992-1003.Springer Nature. doi: 10.1007/s10439-008-9482-3.

Eash, H.J., Mihelc, K.M., Frankowski, B.J., Hattler, B.G., & Federspiel, W.J. (2007). Evaluation of fiber bundle rotation for enhancing gas exchange in a respiratory assist catheter. ASAIO J, 53(3), 368-373.Wolters Kluwer. doi: 10.1097/MAT.0b013e318031af3b.

Federspiel, W. (2007). Basic transport phenomena in biomedical engineering: a review. ASAIO J, 53(3), e7.

Kaar, J.L., Oh, H.I., Russell, A.J., & Federspiel, W.J. (2007). Towards improved artificial lungs through biocatalysis. Biomaterials, 28(20), 3131-3139.Elsevier. doi: 10.1016/j.biomaterials.2007.03.021.

Zinovik, I.N., & Federspiel, W.J. (2007). Modeling of blood flow in a balloon-pulsed intravascular respiratory catheter. ASAIO J, 53(4), 464-468.Wolters Kluwer. doi: 10.1097/MAT.0b013e31805fe96d.

Eash, H.J., Budilarto, S.G., Hattler, B.G., & Federspiel, W.J. (2006). Investigating the effects of random balloon pulsation on gas exchange in a respiratory assist catheter. ASAIO J, 52(2), 192-195.Wolters Kluwer. doi: 10.1097/01.mat.0000199752.89066.83.

Gautam, S., Alikhani, A., Bovin, N.V., & Federspiel, W. (2006). Antibody Removal by Immobilized Synthetic Antigen in Specific Antibody Filters. ASAIO Journal, 52, (p. 13A).

Oh, H.I., Kaar, J.L., Russell, A.J., & Federspiel, W. (2006). Immobilization and assessment of carbonic anhydrase on hollow fiber membranes for enzyme-enhanced artificial lungs. ASAIO Journal, 52, (p. 67A).

Polk, A.A., McKeel, D.T., Federspiel, W., & Wagner, W.R. (2006). A biohybrid lung prototype with active mixing and oxygenation of endothelialized microporous hollow fibers. ASAIO Journal, 52, (p. 67A).

Snyder, T.A., Eash, H.J., Litwak, K.N., Frankowski, B.J., Hattler, B.G., Federspiel, W.J., & Wagner, W.R. (2006). Blood biocompatibility assessment of an intravenous gas exchange device. Artif Organs, 30(9), 657-664.Wiley. doi: 10.1111/j.1525-1594.2006.00281.x.

Solovan, J.C., Oh, H.I., Alikhani, A., Gautam, S., Vlasova, K., Korchagina, E.Y., Bovin, N.V., & Federspiel, W.J. (2006). Synthetic blood group antigens for anti-A removal device and their interaction with monoclonal anti-A IgM. Transpl Immunol, 16(3-4), 245-249.Elsevier. doi: 10.1016/j.trim.2006.08.003.

Budilarto, S.G., Eash, H.J., Hattler, B.G., & Federspiel, W. (2005). Flow visualization study of a pulsating respiratory assist catheter. ASAIO Journal, 51, (p. 53A).

Budilarto, S.G., Frankowski, B.J., Hattler, B.G., & Federspiel, W.J. (2005). Flow visualization study of a pulsating respiratory assist catheter. ASAIO J, 51(6), 673-680.Wolters Kluwer. doi: 10.1097/01.mat.0000187393.79866.9c.

Burgess, K.A., Yang, G., Wagner, W.R., & Federspiel, W. (2005). Development of Microfabricated Biohybrid Artificial Lungs. ASAIO Journal, 51, (p. 53A).

Eash, H.J., Budilarto, S.G., Hattler, B.G., & Federspiel, W. (2005). Can random balloon pulsation enhance gas exchange in a pulsating respiratory support catheter?. ASAIO Journal, 51, (p. 49A).

Eash, H.J., Frankowski, B.J., Hattler, B.G., & Federspiel, W.J. (2005). Evaluation of local gas exchange in a pulsating respiratory support catheter. ASAIO Journal, 51(2), 152-157.Wolters Kluwer. doi: 10.1097/01.MAT.0000153648.11692.D0.

Hagglund, N.J., Frankowski, B.J., Hattler, B.G., & Federspiel, W. (2005). The potential use of rotational fiber bundles in respiratory assist catheters. ASAIO Journal, 51, (p. 53A).

Kanick, S.C., Doyle, W.J., Ghadiali, S.N., & Federspiel, W.J. (2005). On morphometric measurement of oxygen diffusing capacity in middle ear gas exchange. J Appl Physiol (1985), 98(1), 114-119.American Physiological Society. doi: 10.1152/japplphysiol.00203.2004.

Polk, A.A., McKeel, D.T., Federspiel, W., & Wagner, W.R. (2005). A biohybrid lung prototype with endothelialized microporous hollow fibers in a rotating module. ASAIO Journal, 51, (p. 55A).

Svitek, R.G., Frankowski, B.J., & Federspiel, W.J. (2005). Evaluation of a pumping assist lung that uses a rotating fiber bundle. ASAIO J, 51(6), 773-780.Wolters Kluwer. doi: 10.1097/01.mat.0000178970.00971.43.

Svitek, R.G., Frankowski, R.G., & Federspiel, W. (2005). The effect of bundle porosity on the performance of a pumping paracorporeal assist lung using a rotating fiber bundle. ASAIO Journal, 51, (p. 52A).

Eash, H.J., Frankowski, B.J., Hattler, B.G., & Federspiel, W. (2004). Evaluation of local gas exchange in an artificial lung catheter. ASAIO Journal, 50, (p. 153).

Eash, H.J., Jones, H.M., Hattler, B.G., & Federspiel, W.J. (2004). Evaluation of plasma resistant hollow fiber membranes for artificial lungs. ASAIO J, 50(5), 491-497.Wolters Kluwer. doi: 10.1097/01.mat.0000138078.04558.fe.

Federspiel, W., & Henchir, K.A. (2004). Artificial lungs: basic principles and current applications. In Encyclopedia of Biomaterials and Biomedical Engineering, Wneck, G.E., & Bowlin, G.L. (Eds.). (pp. 910-921).Marcel Dekker, Inc.

Federspiel, W., & Svitek, R.G. (2004). Artificial lungs: current research and future directions. In Encyclopedia of Biomaterials and Biomedical Engineering, Wneck, G.E., & Bowlin, G.L. (Eds.). (pp. 922-931).Marcel Dekker, Inc.

Nolan, T.D.C., Hattler, B.G., & Federspiel, W.J. (2004). Development of a balloon volume sensor for pulsating balloon catheters. ASAIO J, 50(3), 225-233.Wolters Kluwer. doi: 10.1097/01.mat.0000123635.20778.52.

Wu, Z.J., & Federspiel, W. (2004). DPIV flow study of a pulsating artificial lung catheter. ASAIO Journal, 50, (p. 173).

Zinovik, I.N., Svitek, R.G., & Federspiel, W. (2004). CFD analysis of hydrodynamic characteristics of a novel paracorporeal pumping artificial lung. ASAIO Journal, 50, (p. 157).

Eash, H.J., Frankowski, B.J., Litwak, K., Wagner, W.R., Hattler, B.G., & Federspiel, W.J. (2003). Acute in vivo testing of a respiratory assist catheter: implants in calves versus sheep. ASAIO J, 49(4), 370-377. doi: 10.1097/01.mat.0000074991.94234.b6.

Hattler, B.G., & Federspiel, W. (2003). The artificial lung. In Lung Transplantation, Banner, N.R., Polak, J.M., & Yacoub, M. (Eds.). (pp. 386-398).Cambridge University Press.

Henchir, K.A., Wagner, W.R., & Federspiel, W. (2003). Microfabrication of biohybrid artificial alveolar - capillary modules. Int. J. Cardiovasc. Med. Sci., 6, (pp. 65-150).

Hout, M.S., & Federspiel, W.J. (2003). Mathematical and experimental analyses of antibody transport in hollow-fiber-based specific antibody filters. Biotechnol Prog, 19(5), 1553-1561.Wiley. doi: 10.1021/bp025796f.

Polk, A.A., Federspiel, W., & Wagner, W.R. (2003). Modified microporous hollow fibers to support endothelial cell adhesion. ASAIO Journal, 49, (p. 217).

Svitek, R.G., Frankowski, B.J., & Federspiel, W. (2003). Enhanced gas exchange in an emergency respiratory support lung. Int. J. Cardiovasc. Med. Sci., 6, (pp. 65-150).

Drevon, G.F., Danielmeier, K., Federspiel, W., Stolz, D.B., Wicks, D.A., Yu, P.C., & Russell, A.J. (2002). High-activity enzyme-polyurethane coatings. Biotechnol Bioeng, 79(7), 785-794.Wiley. doi: 10.1002/bit.10334.

Garcia, M.Y., Hattler, B.G., & Federspiel, W.J. (2002). Effect of vessel compliance on the in-vitro performance of a pulsating respiratory support catheter. J Biomech Eng, 124(1), 56-62.ASME International. doi: 10.1115/1.1428556.

Ghadiali, S.N., Federspiel, W.J., Swarts, J.D., & Doyle, W.J. (2002). Measurement of the viscoelastic compliance of the eustachian tube using a modified forced-response test. Auris Nasus Larynx, 29(1), 1-5.Elsevier. doi: 10.1016/s0385-8146(01)00116-x.

Ghadiali, S.N., Swarts, J.D., & Federspiel, W.J. (2002). Model-based evaluation of eustachian tube mechanical properties using continuous pressure-flow rate data. Ann Biomed Eng, 30(8), 1064-1076.Springer Nature. doi: 10.1114/1.1509764.

Hattler, B.G., & Federspiel, W. (2002). Gas exchange in the venous system: support for the failing lung. In The Artificial Lung, Vaslef, S.N., & Anderson, R.W. (Eds.). (pp. 133-174).Landes Bioscience.

Hattler, B.G., Lund, L.W., Golob, J., Russian, H., Lann, M.F., Merrill, T.L., Frankowski, B., & Federspiel, W.J. (2002). A respiratory gas exchange catheter: in vitro and in vivo tests in large animals. J Thorac Cardiovasc Surg, 124(3), 520-530.Elsevier. doi: 10.1067/mtc.2002.123811.

Hout, M.S., & Federspiel, W. (2002). Kinetics of extracorporeal antibody removal by hollow fiber-based selective antibody filters. ASAIO Journal, 48, (p. 196).

Lai, J., Gouldstone, A., Butler, J.P., Federspiel, W.J., & Loring, S.H. (2002). Relative motion of lung and chest wall promotes uniform pleural space thickness. Respir Physiol Neurobiol, 131(3), 233-243.Elsevier. doi: 10.1016/s1569-9048(02)00091-5.

Lund, L.W., Hattler, B.G., & Federspiel, W.J. (2002). A comparative in vitro hemolysis study of a pulsating intravenous artificial lung. ASAIO J, 48(6), 631-635.Wolters Kluwer. doi: 10.1097/00002480-200211000-00009.

Lund, L.W., Hattler, B.G., & Federspiel, W.J. (2002). Gas permeance measurement of hollow fiber membranes in gas-liquid environment. AICHE JOURNAL, 48(3), 635-643.Wiley. doi: 10.1002/aic.690480320.

Nolan, T.D., Hattler, B.G., & Federspiel, W. (2002). Development of a dynamic balloon volume sensor. ASAIO Journal, 48, (p. 158).

Russian, H.J., Conover, S.P., Hattler, B.G., & Federspiel, W. (2002). Evaluation of plasma resistant coatings for hollow fiber membranes. ASAIO Journal, 48, (p. 155).

Snyder, T.A., Lund, L., Russian, H., Litwak, K.N., Hattler, B.G., Federspiel, W., & Wagner, W.R. (2002). Assessing and improving the biocompatibility of an intravascular oxygenator. Trans. Soc. Biomat., 28, (p. 37).

Snyder, T.A., Russian, H.J., Litwak, K.N., Federspiel, W., Hattler, B.G., & Wagner, W.R. (2002). Assessing thrombosis of an intravascular respiratory support catheter. ASAIO Journal, 48, (p. 154).

Garcia, M.Y., Federspiel, W., & Hattler, B.G. (2001). Effect of vessel compliance on the in-vitro performance of a pulsating respiratory support catheter. ASAIO Journal, 47, (p. 172).

Garcia, M.Y., Hattler, B.G., & Federspiel, W. (2001). Effect of vessel compliance on the in-vitro performance of a pulsating respiratory support catheter. Ann. Biomed. Eng., 29, (p. S5).

Ghadiali, S.N., Federspiel, W.J., Douglas Swarts, J., & Doyle, W.J. (2001). Measurement of Eustachian tube mechanical properties using a modified forced response test. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, 50, (pp. 443-444).Snowbird, UT.

Golob, J.F., Federspiel, W.J., Merrill, T.L., Frankowski, B.J., Litwak, K., Russian, H., & Hattler, B.G. (2001). Acute in vivo testing of an intravascular respiratory support catheter. ASAIO J, 47(5), 432-437.Wolters Kluwer. doi: 10.1097/00002480-200109000-00003.

Hout, M.S., & Federspiel, W. (2001). Design of hollow fiber immunoadsorption modules for therapeutic antibody removal. ASAIO Journal, 47, (p. 172).

Hout, M.S., & Federspiel, W. (2001). Kinetics of antibody capture by hollow fiber-based selective antibody filters. Ann. Biomed. Eng., 29, (p. S87).

Lund, L.W., Franklin-Ford, T., Russian, H.J., Hattler, B.G., & Federspiel, W. (2001). A comparative in-vitro hemolysis study of a pulsating intravenous artificial lung. ASAIO Journal, 47, (p. 115).

Snyder, T.A., Watach, M.K., Gordon, L.M., Litwak, K.N., Lund, L.W., Golob, J.F., Federspiel, W., Hattler, B.G., & Wagner, W.R. (2001). Evaluating biocompatibility in an intravenous membrane oxygenator. Trans. Soc. Biomat., 27, (p. 420).

Federspiel, W., & Hattler, B.G. (2000). Development of an intravenous respiratory support catheter. Ann. Biomed. Eng., 28, (pp. S-2).

Federspiel, W.J., Golob, J.F., Merrill, T.L., Lund, L.W., Bultman, J.A., Frankowski, B.J., Watach, M., Litwak, K., & Hattler, B.G. (2000). Ex vivo testing of the intravenous membrane oxygenator. ASAIO J, 46(3), 261-267.Wolters Kluwer. doi: 10.1097/00002480-200005000-00004.

Federspiel, W.J., Hewitt, T.J., & Hattler, B.G. (2000). Experimental evaluation of a model for oxygen exchange in a pulsating intravascular artificial lung. Ann Biomed Eng, 28(2), 160-167.Springer Nature. doi: 10.1114/1.240.

Golob, J.F., Federspiel, W.J., Merrill, T.L., Frankowski, B.J., Russian, H.J., Litwak, K., & Hattler, B.G. (2000). ACUTE IN-VIVO TESTING OF THE INTRAVENOUS MEMBRANE OXYGENATOR (IMO). ASAIO Journal, 46, (p. 180).Wolters Kluwer. doi: 10.1097/00002480-200003000-00119.

Hout, M.S., & Federspiel, W.J. (2000). Kinetics of antibody removal by dialysis membrane immunoadsorption. ASAIO Journal, 46, (p. 230).Wolters Kluwer. doi: 10.1097/00002480-200003000-00318.

Hout, M.S., Hattler, B.G., & Federspiel, W.J. (2000). Validation of a model for flow-dependent carbon dioxide exchange in artificial lungs. Artif Organs, 24(2), 114-118.Wiley. doi: 10.1046/j.1525-1594.2000.06465.x.

Hout, M.S., LeJeune, K.E., Schaack, T.M., Bristow, D.K., & Federspiel, W.J. (2000). Specific removal of anti-A and anti-B antibodies by using modified dialysis filters. ASAIO J, 46(6), 702-706.Wolters Kluwer. doi: 10.1097/00002480-200011000-00010.

Merrill, T.L., Hattler, B.G., & Federspiel, W.J. (2000). DETERMINING OXYGEN EXCHANGE FROM GAS-SIDE ANALYSIS IN ARTIFICIAL LUNGS. ASAIO Journal, 46, (p. 180).Wolters Kluwer. doi: 10.1097/00002480-200003000-00118.

Tulou, T., Hattler, B.G., & Federspiel, W. (2000). Development of a balloon drive system for the intravascular membrane oxygenator. ASAIO Journal, 46, (p. 230).Wolters Kluwer. doi: 10.1097/00002480-200003000-00317.

Federspiel, W., Lund, L.W., Bultman, J.A., Wanant, S., Matoney, J., Golob, J.F., Frankowski, B.J., Watach, M., Litwak, P., & Hattler, B.G. (1999). Ex-vivo testing of the intravenous membrane oxygenator (IMO). ASAIO Journal, 45, (p. 127).

Federspiel, W.J., Golob, J.F., Frankowski, B.J., Merrill, T.L., Litwak, K., & Hattler, B.G. (1999). Development and testing of an intravascular artificial lung. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 1, (p. 345).

Golob, J.F., Federspiel, W., Merrill, T.L., Frankowski, B.J., & Hattler, B.G. (1999). Analysis of in-vivo flow effects on the in-vitro testing of intravascular oxygenators. ASAIO Journal, 45, (p. 126).

Hattler, B.G., & Federspiel, W.J. (1999). Progress with the development of the intravenous membrane oxygenator. Perfusion, 14(4), 311-315.SAGE Publications. doi: 10.1177/026765919901400411.

Hout, M.S., LeJeune, K.E., Schaack, T.M., Bristow, D.K., & Federspiel, W.J. (1999). Specific removal of anti-A and anti-B antibodies using modified dialysis filters. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 2, (p. 740).Atlanta, GA.

Hout, M.S., LeJeune, K.E., Schaak, T., Bristow, D., & Federspiel, W. (1999). Specific removal of anti-A and anti-B antibodies using modified dialysis and plasmapheresis filters. ASAIO Journal, 45, (p. 193).

Lund, L.W., & Federspiel, W.J. (1999). Augmentation of oxygen flux from hollow fiber membranes in blood. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 2, (p. 771).Atlanta, GA.

Guzman, A.M., Amon, C.H., Federspiel, W., & Hattler, B.G. (1998). Spectral-element simulations of the flow kinematics in an intravenous membrane oxygenator. In Computational Mechanics, CIMNE, Dvorkin, E., Idelsohn, S., & Onate, E. (Eds.). Barcelona.

Hewitt, T.J., Hattler, B.G., & Federspiel, W.J. (1998). A mathematical model of gas exchange in an intravenous membrane oxygenator. Ann Biomed Eng, 26(1), 166-178.Springer Nature. doi: 10.1114/1.53.

Hout, M.S., Hattler, B.G., & Federspiel, W. (1998). A simple model of flow-dependent CO2 exchange in artificial lungs. ASAIO Journal, 44, (p. 7).

Lund, L.W., Hattler, B.G., & Federspiel, W. (1998). Analysis of condensation as a cause of plasma leakage in microporous membrane oxygenators. ASAIO Journal, 44, (p. 23).

Lund, L.W., Hattler, B.G., & Federspiel, W.J. (1998). Is condensation the cause of plasma leakage in microporous hollow fiber membrane oxygenators. JOURNAL OF MEMBRANE SCIENCE, 147(1), 87-93.Elsevier. doi: 10.1016/S0376-7388(98)00121-5.

Vorp, D.A., Wang, D.H.J., Webster, M.W., & Federspiel, W.J. (1998). Effect of intraluminal thrombus thickness and bulge diameter on the oxygen diffusion in abdominal aortic aneurysm. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 120(5), 579-583.ASME International. doi: 10.1115/1.2834747.

Federspiel, W., Hout, M.S., Hewitt, T.J., Lund, L.W., Heinrich, S.A., Macha, M., Litwak, P., Walters, F.R., Borovetz, H.S., & Hattler, B.G. (1997). Development of a low flow resistance intravenous oxygenator. ASAIO Journal, 43, (p. 14).

Federspiel, W.J., Hout, M.S., Hewitt, T.J., Lund, L.W., Heinrich, S.A., Litwak, P., Walters, F.R., Reeder, G.D., Borovetz, H.S., & Hattler, B.G. (1997). Development of a low flow resistance intravenous oxygenator. ASAIO J, 43(5), M725-M730.Wolters Kluwer. doi: 10.1097/00002480-199709000-00079.

Kameneva, M.V., Borovetz, H.S., Antaki, J.F., Litwak, P., Federspiel, W.J., Kormos, R.L., & Griffith, B.P. (1997). Effect of perfluorochemical emulsion on hemorheology and shear induced blood trauma. Possible mechanisms and future applications. Adv Exp Med Biol, 411, 383-390.Springer Nature. doi: 10.1007/978-1-4615-5865-1_49.

Vorp, D.A., Wang, D.H.J., Webster, M.W., & Federspiel, W.J. (1997). Computational analysis of the oxygen flow in abdominal aortic aneurysm: Effect of intraluminal thrombus thickness and aneurysm diameter. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, 35, 73-74.

Federspiel, W., Swazik, P., Borovetz, H., Reeder, G.D., & Hattler, B.G. (1996). Temporary support of the lungs - the artificial lung. In The Transplantation and Replacement of Thoracic Organs, Cooper, D.K., Miller, L.W., & Patterson, G.A. (Eds.). Kluwer Academic Publishers.

Federspiel, W., Walters, F., Hewitt, T., Hout, M., Lund, L., Sawzik, P., Reeder, G., Borovetz, H., & Hattler, B.G. (1996). Recent progress in engineering the Pittsburgh intravenous membrane oxygenator. ASAIO Journal, 42, (p. 71).

Federspiel, W., Walters, F.R., Hewitt, T., Hout, M.S., Lund, L., & Hattler, B.G. (1996). Further development of an intravenous membrane oxygenator with active mixing. Ann. Biomed. Eng., 24, (p. S6).

Federspiel, W.J., & Hattler, B.G. (1996). Sweep gas flow-rate and CO2 exchange in artificial lungs. ARTIFICIAL ORGANS, 20(9), 1050-1052.Wiley. doi: 10.1111/j.1525-1594.1996.tb04593.x.

Federspiel, W.J., Hewitt, T., Hout, M.S., Walters, F.R., Lund, L.W., Sawzik, P.J., Reeder, G., Borovetz, H.S., & Hattler, B.G. (1996). Recent progress in engineering the Pittsburgh intravenous membrane oxygenator. ASAIO J, 42(5), M435-M442.Wolters Kluwer. doi: 10.1097/00002480-199609000-00026.

Federspiel, W.J., Williams, J.L., & Hattler, B.G. (1996). Gas flow dynamics in hollow-fiber membranes. AICHE JOURNAL, 42(7), 2094-2099.Wiley. doi: 10.1002/aic.690420732.

Hout, M.S., Hattler, B.G., & Federspiel, W. (1996). A simple model of flow dependent CO2 exchange in artificial lungs. Ann. Biomed. Eng., 24, (p. S8).

Konishi, R., Firestone, W., Wagner, W., Federspiel, W., Konishi, H., Shimizu, R., & Hattler, B.G. (1996). Nitric oxide presents human platelet adhesion on fiber membrane in whole blood. ASAIO Journal, 42, (p. 72).

Konishi, R., Shimizu, R., Firestone, L., Walters, F.R., Wagner, W.R., Federspiel, W.J., Konishi, H., & Hattler, B.G. (1996). Nitric oxide prevents human platelet adhesion to fiber membranes in whole blood. ASAIO J, 42(5), M850-M853.Wolters Kluwer. doi: 10.1097/00002480-199609000-00111.

Lund, L., Federspiel, W., Taitel, F., & Hattler, B.G. (1996). A novel method for measuring hollow fiber membrane permeability in a gas-liquid system. ASAIO Journal, 42, (p. 67).

Lund, L.W., Federspiel, W., & Hattler, B.G. (1996). Hollow fiber membrane permeability evaluation for use in intracorporeal artificial lungs. Ann. Biomed. Eng., 24, (p. S8).

Lund, L.W., Federspiel, W.J., & Hattler, B.G. (1996). Gas permeability of hollow fiber membranes in a gas-liquid system. JOURNAL OF MEMBRANE SCIENCE, 117(1-2), 207-219.Elsevier. doi: 10.1016/0376-7388(96)00064-6.

Lund, L.W., Federspiel, W.J., Walters, F.R., & Hattler, B.G. (1996). A novel method for measuring hollow fiber membrane permeability in a gas-liquid system. ASAIO J, 42(5), M446-M451.Wolters Kluwer. doi: 10.1097/00002480-199609000-00028.

Macha, M., Federspiel, W., Lund, L., Sawzik, P., Litwak, P., Borovetz, H., Walters, F., Reeder, G., & Hattler, B.G. (1996). Acute in-vivo studies of the Pittsburgh intravenous membrane oxygenator. ASAIO Journal, 42, (p. 69).

Macha, M., Federspiel, W.J., Lund, L.W., Sawzik, P.J., Litwak, P., Walters, F.R., Reeder, G.D., Borovetz, H.S., & Hattler, B.G. (1996). Acute in vivo studies of the Pittsburgh intravenous membrane oxygenator. ASAIO J, 42(5), M609-M615.Wolters Kluwer. doi: 10.1097/00002480-199609000-00060.

Vorp, D.A., Federspiel, W.J., & Webster, M.W. (1996). Does laminated intraluminal thrombus within abdominal aortic aneurysm cause anoxia of the aortic wall?. J Vasc Surg, 23(3), 540-541.Elsevier. doi: 10.1016/s0741-5214(96)80027-9.

CHAMMAS, P., FEDERSPIEL, W.J., & EISENBERG, S.R. (1994). A MICROCONTINUUM MODEL OF ELECTROKINETIC COUPLING IN THE EXTRACELLULAR-MATRIX - PERTURBATION FORMULATION AND SOLUTION. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 168(2), 526-538.Elsevier. doi: 10.1006/jcis.1994.1451.

Federspiel, W.J., & Malai, K. (1993). Model experiments on measuring flow in microvessels using tracers. Microvasc Res, 46(3), 333-350.Elsevier. doi: 10.1006/mvre.1993.1057.

Weibel, E.R., Federspiel, W.J., Fryder-Doffey, F., Hsia, C.C., König, M., Stalder-Navarro, V., & Vock, R. (1993). Morphometric model for pulmonary diffusing capacity. I. Membrane diffusing capacity. Respir Physiol, 93(2), 125-149.Elsevier. doi: 10.1016/0034-5687(93)90001-q.

Bunk, D.A., Federspiel, W.J., & Jackson, A.C. (1992). Influence of bifurcations on forced oscillations in an airway model. J Biomech Eng, 114(2), 216-221.ASME International. doi: 10.1115/1.2891374.

FEDERSPIEL, W.J. (1992). ANALYSIS OF EFFECTIVE AXIAL DIFFUSION IN BRANCHING NETWORKS. AICHE JOURNAL, 38(10), 1631-1638.Wiley. doi: 10.1002/aic.690381013.

Lai, J., Federspiel, W., Butler, J.P., & Loring, S.H. (1992). A computational study of pleural pressure induced by lung motion. FASEB Journal, 6, (p. A1480).

Malai, K.P., & Federspiel, W. (1992). Use of tracers to measure flow in branching microvessels. FASEB Journal, 6, (p. A2079).

Federspiel, W. (1991). On the trumpet model of acinar gas transport. In Advances in Biological Heat and Mass Transfer, McGrath, J.J. (Ed.). 18, (pp. 39-42).ASME Bioengineering Division.

TSUDA, A., FEDERSPIEL, W.J., GRANT, P.A., & FREDBERG, J.J. (1991). AXIAL-DISPERSION OF INERT SPECIES IN ALVEOLATED CHANNELS. CHEMICAL ENGINEERING SCIENCE, 46(5-6), 1419-1426.Elsevier. doi: 10.1016/0009-2509(91)85068-9.

Federspiel, W. (1990). Use of tracers to measure plasma flow within individual microvessels. FASEB Journal, 4, (p. A1251).

Federspiel, W. (1990). Nonclassical features of gas transport and exchange at the alveolar level. In Respiratory Biomechanics: Engineering Analysis of Structure and Function, Farrell-Epstein, M.A., & Ligas, J.R. (Eds.). (pp. 90-97).Springer Verlag.

Federspiel, W. (1990). Fluid mechanics in alveolar ducts. In Biofluid Mechanics 3, Schneck, D.J., & Lucas, C.L. (Eds.). (pp. 21-25).New York University Press.

Federspiel, W.J. (1990). Use of tracers to measure flow within single microvessels. Microvasc Res, 40(3), 394-411.Elsevier. doi: 10.1016/0026-2862(90)90035-p.

Federspiel, W.J. (1989). Pulmonary diffusing capacity: implications of two-phase blood flow in capillaries. Respir Physiol, 77(1), 119-134.Elsevier. doi: 10.1016/0034-5687(89)90035-2.

Tsuda, A., Federspiel, W., Grant Jr, P.A., & Fredberg, J.J. (1989). Axial dispersion of inert species in alveolated ducts. Fed. Proc., 3, (p. A686).

Federspiel, W. (1988). Influence of the particulate nature of blood on pulmonary oxygen exchange. The Physiologist, 31, (p. A170).

Federspiel, W.J., & Fredberg, J.J. (1988). Axial dispersion in respiratory bronchioles and alveolar ducts. J Appl Physiol (1985), 64(6), 2614-2621.American Physiological Society. doi: 10.1152/jappl.1988.64.6.2614.

Gayeski, T.E., Federspiel, W.J., & Honig, C.R. (1988). A graphical analysis of the influence of red cell transit time, carrier-free layer thickness, and intracellular PO2 on blood-tissue O2 transport. Adv Exp Med Biol, 222, 25-35.Springer Nature. doi: 10.1007/978-1-4615-9510-6_3.

Federspiel, W., & Fredberg, J.J. (1987). Gas transport in respiratory bronchioles and alveolar ducts. Fed. Proc., 46, (p. 1427).

Federspiel, W., & Fredberg, J.J. (1986). Influence of structural complexity on axial dispersion in the acinus. The Physiologist, 29, (p. 94).

Federspiel, W.J. (1986). A model study of intracellular oxygen gradients in a myoglobin-containing skeletal muscle fiber. Biophys J, 49(4), 857-868.Elsevier. doi: 10.1016/S0006-3495(86)83715-8.

Federspiel, W.J., & Popel, A.S. (1986). A theoretical analysis of the effect of the particulate nature of blood on oxygen release in capillaries. Microvasc Res, 32(2), 164-189.Elsevier. doi: 10.1016/0026-2862(86)90052-x.

Clark, A., Federspiel, W.J., Clark, P.A., & Cokelet, G.R. (1985). Oxygen delivery from red cells. Biophys J, 47(2 Pt 1), 171-181.Elsevier. doi: 10.1016/s0006-3495(85)83890-x.

CLARK, A., FEDERSPIEL, W.J., CLARK, P.A.A., & COKELET, G.R. (1985). OXYGEN DELIVERY FROM RED-CELLS. BIOPHYSICAL JOURNAL, 47(2), 171-181. doi: 10.1016/S0006-3495(85)83890-X.

Federspiel, W., & Popel, A.S. (1984). A theoretical analysis of the effect of the particulate nature of blood on oxygen release in capillaries. Int. J. Microcirc., 3, (p. 407).

Federspiel, W.J. (1984). The effect of myoglobin concentration on muscle cell PO2 gradients. Adv Exp Med Biol, 180, 539-543.Springer Nature. doi: 10.1007/978-1-4684-4895-5_51.

Federspiel, W.J., & Cokelet, G.R. (1984). BLOOD VISCOELASTICITY FOR CONDITIONS OF PHYSIOLOGICAL FLOW IN SMALL ARTERIES. CHEMICAL ENGINEERING COMMUNICATIONS, 30(3-5), 275-284.Taylor & Francis. doi: 10.1080/00986448408911132.

Federspiel, W.J., & Sarelius, I.H. (1984). An examination of the contribution of red cell spacing to the uniformity of oxygen flux at the capillary wall. Microvasc Res, 27(3), 273-285.Elsevier. doi: 10.1016/0026-2862(84)90059-1.

Honig, C.R., Gayeski, T.E., Federspiel, W., Clark, A., & Clark, P. (1984). Muscle O2 gradients from hemoglobin to cytochrome: new concepts, new complexities. Adv Exp Med Biol, 169, 23-38.Springer Nature. doi: 10.1007/978-1-4684-1188-1_2.

Federspiel, W., & Cokelet, G.R. (1983). Prediction of time dependent blood flow in small glass tubes. Microvasc. Res., 25, (p. 233).

Federspiel, W., Clark Jr, A., & Cokelet, G.R. (1982). Oxygen delivery: the view from the red cell. Microvasc. Res., 23, (p. 251).

Clark Jr, A., Cokelet, G.R., & Federspiel, W. (1981). Erythrocyte motion and oxygen transport. Biblthca. Anat., 20, 385-388.

Madhani, S., May, A., Frankowski, B., Burgreen, G., & Federspiel, W. Blood Recirculation Enhances Oxygenation Efficiency of Artificial Lungs. ASAIO Journal.Lippincott, Williams & Wilkins.

Madhani, S.P., May, A.G., Frankowski, B.J., Burgreen, G.W., & Federspiel, W.J. (2020). Blood Recirculation Enhances Oxygenation Efficiency of Artificial Lungs. 44th ESAO and 7th Biennial IFAO Congress.United States. doi: 10.1097/MAT.0000000000001030.

Dhamotharan, V., Orizondo, R., & Federspiel, W. (2019). A quantitative approach to detection of increased circuit resistance during ECMO. American Society of Artificial Internal Organs (ASAIO) 65th Annual Conference.San Francisco, CA.

Dhamotharan, V., Orizondo, R.A., & Federspiel, W. (2019). A Quantitative Approach to Detection of Increased Circuit Resistance during ECMO. Poster session presented at the meeting of McGowan Institute Scientific Retreat.

Federspiel, W., May, A., & Orizondo, R. (2019). 7-day In Vivo Performance of a Low-Flow Extracorporeal CO2 Removal Device. Poster session presented at the meeting of McGowan Institute Scientific Retreat.

May, A., Orizondo, R., Frankowski, B.J., Kocyildirim, E., D’Cunha, J., & Federspiel, W. (2019). 7-day In Vivo Performance of a Low-Flow Extracorporeal CO2 Removal Device. American Society of Artificial Internal Organs (ASAIO) 65th Annual Conference.San Francisco.

May, A., Orizondo, R.A., Frankowski, B., Wearden, P.D., & Federspiel, W. (2019). Acute In Vivo Performance of a Pediatric Ambulatory Artificial Lung. Poster session presented at the meeting of McGowan Institute Scientific Retreat.

Omecinski, K.S., Frankowski, B.J., & Federspiel, W. (2019). Characterization of Floating Impeller Phenomena in an Integrated HFM bundle and Centrifugal Pump Design. Poster session presented at the meeting of McGowan Institute Scientific Retreat.Pittsburgh, PA.

Orizondo, R.A., May, A., Frankowski, B.J., Burgreen, G., Ye, S., Kocyildirim, E., Wagner, W., D’Cunha, J., Kormos, R., & Federspiel, W. (2019). Pittsburgh Paracorporeal Ambulatory Assist Lung: Progress Towards a Long-Term Wearable Artificial Lung. American Society of Artificial Internal Organs (ASAIO) 65th Annual Conference.San Francisco.

Behrangzade, A., Orizondo, R.A., Kellum, J.A., & Federspiel, W. (2018). Development of a Combined Artificial Lung and Kidney. Poster session presented at the meeting of McGowan Institute Scientific Retreat.Pittsburgh, PA.

May, A., Orizondo, R., Frankowski, B.J., Wearden, P.D., & Federspiel, W. (2018). Acute In Vivo Performance of a Pediatric Ambulatory Artificial Lung. 64th Annual American Society for Artificial Internal Organs (ASAIO) Conference.Washington DC.

May, A.G., Orizondo, R.A., Frankowski, B.J., Wearden, P.D., & Federspiel, W. (2018). Acute In Vivo Performance of a Pediatric Ambulatory Artificial Lung. Poster session presented at the meeting of McGowan Institute Scientific Retreat.Pittsburgh, PA.

Orizondo, R., Madhani, S., May, A., Frankowski, B.J., Ye, S., Kocyildirim, E., Wagner, W., Kormos, R., D’Cunha, J., & Federspiel, W. (2018). Successful 30-day Sheep Studies of a Wearable Pumping Artificial Lung. Poster session presented at the meeting of McGowan Institute Scientific Retreat.Pittsburgh, PA.

Orizondo, R., May, A., Frankowski, B.J., Burgreen, G.W., & Federspiel, W. (2018). In Vitro Characterization of a Modular Pump Lung Capable of Multiple Respiratory Assist Applications. Poster session presented at the meeting of McGowan Institute Scientific Retreat.Pittsburgh, PA.

Orizondo, R.A., Madhani, S.P., May, A., Frankowski, B.J., Burgreen, G.W., Ye, S., Kocyildirim, E., Wagner, W., Kormos, R.L., D'Cunha, J., & Federspiel, W. (2018). 30 Day Sheep Studies of a Wearable Pumping Artificial Lung. 64th Annual American Society for Artificial Internal Organs (ASAIO) Conference.Washington, DC.

Orizondo, R.A., May, A.G., Frankowski, B.J., Burgreen, G.W., & Federspiel, W. (2018). In Vitro Characterization of a Modular Pump Lung Capable of Multiple Respiratory Assist Applications. 64th Annual American Society for Artificial Internal Organs (ASAIO) Conference.Washington, DC.

Richards, E., Federspiel, W., Liu, X., Sharma, A.C., Ghosh, R., & Ye, S. (2018). Advancing a System for Generating Universal Blood Plasma. Poster session presented at the meeting of McGowan Institute Scientific Retreat.Pittsburgh, PA.

Jeffries, R., Frankowski, B., & Federspiel, W. (2017). High Efficiency Respiratory Dialysis at Ultra-Low Blood Flows. Poster session presented at the meeting of McGowan Institute Scientific Retreat.Farmington, PA.

Madhani, S., Ye, S.H., Frankowski, B.J., Burgreen, G.W., Antaki, J.F., May, A., Kormos, R., Wagner, W.R., D’Cunha, J., & Federspiel, W.J. (2017). Chronic In-Vivo Studies of an Integrated Wearable Pump-lung. ASAIO 63rd Annual Conference.Chicago, IL.

Madhani, S., Ye, S.H., Frankowski, B.J., Burgreen, G.W., Antaki, J.F., May, A., Kormos, R., Wagner, W.R., D’Cunha, J., & Federspiel, W.J. (2017). Chronic In-Vivo Studies of an Integrated Wearable Pump-lung. ASAIO 63rd Annual Conference.Chicago, IL.

Madhani, S.P., Ye, S., Frankowski, B.J., Burgreen, G.W., Antaki, J.W., Kormos, R., Wagner, W.R., D’Cunha, J., & Federspiel, W. (2017). Chronic In-Vivo Studies of an Integrated Wearable Pump-lung. 44th ESAO and 7th Biennial IFAO Congress.Vienna, Austria.

Malkin, A., Federspiel, W., Kellum, J., & Singbartl, K. (2017). An Extracorporeal Neutrophil Reprogramming Device for the Treatment of Acute Inflammatory Conditions. Poster session presented at the meeting of McGowan Institute Scientific Retreat.Farmington, PA.

May, A.G., Jeffries, R.G., Frankowski, B.J., & Federspiel, W. (2017). Integrated Low Flow Extracorporeal CO2 Removal Device. Poster session presented at the meeting of 44th ESAO and 7th Biennial IFAO Congress.Vienna, Austria.

Orizondo, R., May, A., Madhani, S., Frankowski, B., Wearden, P., & Federspiel, W. (2017). Pittsburgh Pediatric Ambulatory Lung (P-PAL). Poster session presented at the meeting of McGowan Institute Scientific Retreat.Farmington, PA.

Orizondo, R.A., Gino, G., Sultzbach, G., Madhani, S.P., Frankowski, B.J., & Federspiel, W. (2017). Effects of Hollow Fiber Oscillation on Artificial Lungs. Poster session presented at the meeting of ASAIO 63rd Annual Conference.Chicago, IL.

Orizondo, R.A., Gino, G., Sultzbach, G., Madhani, S.P., Frankowski, B.J., & Federspiel, W. (2017). Effects of Hollow Fiber Oscillation on Artificial Lungs. Poster session presented at the meeting of 44th ESAO and 7th Biennial IFAO Congress.Vienna, Austria.

Orizondo, R.A., May, A., Madhani, S.P., Frankowski, B.J., Burgreen, G.W., Wearden, P.D., & Federspiel, W. (2017). In vitro Characterization and In vivo Performance of the Pittsburgh Pediatric Ambulatory Lung Device. 13th International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion.Rome, Italy.

Orizondo, R.A., May, A.G., Madhani, S.P., Frankowski, B.J., Burgreen, G.W., Wearden, P.D., & Federspiel, W. (2017). In Vitro Characterization of the Pittsburgh Pediatric Ambulatory Lung (P-PAL). 44th ESAO and 7th Biennial IFAO Congress.Vienna, Austria.

Kimmel, J.D., Arazawa, D., & Federspiel, W. (2012). Bioactive Hollow Fiber Membranes Coated with Chitosan and Carbonic Anhydrase for Artificial Lung Applications. Poster session presented at the meeting of University of Pittsburgh Postdoctoral Association 2012 Postdoctoral Data & Dine Symposium.Pittsburgh, PA.

Vodovotz, Y., Valenti, I., Peng, Z., Namas, R., Mi, Q., Kellum, J., Federspiel, W., DiLeo, M., & Barclay, D. (2011). Effects of Hemoadsorption of inflammation in e.coli induced fibrin peritonitis. Society of Critical Care Medicine Annual Meeting.

DiLeo, M.V., & Federspiel, W. (2010). Selective improvement of TNF capture in a cytokine hemoadsorption device using immobilized anti-TNF. Poster session presented at the meeting of University of Pittsburgh Safar Conference.Pittsburgh, PA.

Kimmel, J., Lacko, C., Kellum, J., & Federspiel, W. (2010). TNF Capture Dynamics within Hemoadsorption Beads Used to Treat Sepsis. Poster session presented at the meeting of University of Pittsburgh Safar Conference.Pittsburgh, PA.

Kimmel, J.D., Gibson, G.A., Watkins, S.C., & Federspiel, W. (2009). Dynamics of cytokine capture within hemoadsorption beads used to treat sepsis. BMES Conference.Pittsburgh, PA.

Rothstein, S.N., Federspiel, W., & Little, S. (2008). Towards the Rational Design of Controlled Release Therapeutics. AIChE 2008 Annual Meeting.Philadelphia, PA.

Rothstein, S.N., Federspiel, W., & Little, S. (2008). Towards the Rational Design of Biodegradable Controlled Release Vehicles. AIChE 2008 Annual Meeting.Philadelphia, PA.

Rothstein, S.N., Federspiel, W., & Little, S. (2008). A unified mathematical model for predicting controlled release from surface and bulk eroding matrices without regression. Poster session presented at the meeting of AIChE 2008 Annual Meeting.Philadelphia, PA.

Rothstein, S.N., Federspiel, W., & Little, S. (2008). Towards the Rational Design of Controlled Release Therapeutics. Biotechnology and Bioengineering Research Symposium. Biomedical Engineering Graduate Society Symposium, Carnegie Mellon University.Pittsburgh, PA.

Oh, H.I., Solovan, J.C., Alikhani, A.H., & Federspiel, W. (2005). Design of Specific Antibody Filters to Facilitate ABO-Blood Incompatible Transplantation. Poster session presented at the meeting of McGowan Institute Scientific Retreat.Farmington, PA.

Ghadiali, S.N., Swarts, J.D., Federspiel, W., Banks, J., Karnavas, W., & Doyle, W.J. (2001). Demonstration of eustachian tube compliance using a modified forced response system. Association for Research in Otolaryngology Mid-winter Meeting.St. Petersburg, FL.

Federspiel, W. (1990). Fluid Mechanics in Alveolar Ducts. Annual Fall Meeting of the Biomedical Engineering Society.Blacksburg, VA.

Federspiel, W., Kellum, J., & Singbartl, K. (2019). Devices, Systems And Methods For Cell Modification. 10,258,734.

Federspiel, W., Frankowski, B., Antaki, J., Bermudez, C., Jeffries, R., Wagner, W., & Ye, S. (2018). Extracorporeal ambulatory assist lung. 10,080,834.

Jeffries, R., Federspiel, W., & Frankowski, B. (2018). Extracorporeal Gas Exchange Devices, Systems and Methods.

Madhani, S., Frankowski, B., Federspiel, W., Burgreen, G., & Antaki, J. (2018). Extracorporeal Ambulatory Assist Lung.

Madhani, S.P., Frankowski, B.J., Federspiel, W., Burgreen, G., & Antaki, J.F. (2018). Extracorporeal Ambulatory Assist Lung.

Federspiel, W., Arazawa, D., & Kimmel, J. (2017). Devices, Systems And Methods For Reducing The Concentration Of Carbon Dioxide In Blood. 9,814,821.

Federspiel, W., Kellum, J., & Singbartl, K. (2017). Devices, Systems And Methods For Cell Modification.

Federspiel, W., Kellum, J., & Singbartl, K. (2017). Devices, Systems And Methods For Cell Modification.

Madhani, S., Frankowski, B., & Federspiel, W. (2017). Lung Assist Device With Oscillating Fiber Bundle. 15/288,111.

Federspiel, W., Frankowski, B., Yoshida, T., & Vernucci, P. (2016). Oxygen depletion devices and methods for removing oxygen from red blood cells. 9,296,990.

Madhani, S., Frankowski, B., & Federspiel, W. (2016). Lung Assist Device with Oscillating Fiber Bundle.

Madhani, S.P., Frankowski, B.J., & Federspiel, W. (2016). Extracorporeal Ambulator Assist Lung.

Federspiel, W., Arazawa, D.T., & Kimmel, J.D. (2015). Devices, Systems And Methods For Reducing The Concentration Of Carbon Dioxide In Blood. 14/405038.

Federspiel, W., Frankowski, B.J., Antaki, J.F., Bermudez, C., Jeffries, R.G., & Wagner, W.R. (2015). Extracorporeal Ambulator Assist Lung. 14/647,861.

Federspiel, W., Frankowski, B.J., Antaki, J.F., Bermudez, C., Jeffries, R.G., & Wagner, W.R. (2015). Extracorporeal Ambulator Assist Lung.

Jeffries, R.G., Federspiel, W., & Frankowski, B.J. (2015). Extracorporeal Gas Exchange Devices, Systems and Methods.

Jeffries, R.G., Federspiel, W., & Frankowski, B.J. (2015). Extracorporeal Gas Exchange Devices, Systems And Methods.

Kellum, J.A., & Federspiel, W. (2015). Removal of Carbon Dioxide via Dialysis. 14/761,321.

Madhani, S.P., Frankowksi, B.J., & Federspiel, W. (2015). Lung Assist Device with Oscillating Fiber Bundle.

Federspiel WJ, Frankowski BJ, Mack BC, Morley SW, Rosenberg M, & Svitek RG. (2014). Paracorporeal Respiratory Assist Lung. 13/084100.

Federspiel, W., Frankowski, B.J., Mack, B.C., Morley, S.W., Rosenberg, M., & Svitek, R.G. (2014). Paracorporeal Respiratory Assist Lung. 8,647,569.

Frankowski BJ, Federspiel WJ, Mihelc KM, & Lieber SC. (2014). Intracorporeal Gas Exchange Devices, Systems and Methods. 8,734,382.

Frankowski, B.J., Federspiel, W., Mihelc, K.M., & Lieber, S.C. (2014). Intracorporeal Gas Exchange Devices, Systems and Methods. 8,734,382.

Kellum, J.A., Federspiel, W., & Cove, M. (2014). Removal of Carbon Dioxide Via Dialysis. PCT/US2014/012151.

Federspiel WJ, Frankowski BJ, Yoshida T, & Vernucci PJ. (2013). Oxygen depletion devices and methods for removing oxygen from red blood cells. 14/038,001.

Federspiel WJ, Frankowski BJ, Yoshida T, & Vernucci PJ. (2013). Oxygen depletion devices and methods for removing oxygen from red blood cells. 8,569,052.

Federspiel, W., Arazawa, D.T., & Kimmel, J.D. (2013). Devices, Systems And Methods For Reducing The Concentration Of Carbon Dioxide In Blood. PCT/US2013/046042.

Federspiel, W., Frankowski, B.J., Antaki, J., Bermudez, C., Jeffries, R.G., & Wagner, W.R. (2013). Extracorporeal Ambulator Assist Lung.

Kellum, J.A., Federspiel, W., & Cove, M.E. (2013). Removal of Carbon Dioxide Via Dialysis. 61/754,435.

Federspiel WJ, Kellum JA, & Singbartl K. (2012). Devices Systems and Methods for Cell Modification. PCT/US2010/051772.

Federspiel WJ, Yoshida T, Vernucci PJ, Frankowski BJ, & Wheeler Lund L. (2012). Removal Of Oxygen From Biological Fluids. 13/387,528.

Federspiel, W., Arazawa, D.T., & Kimmel, J.D. (2012). Devices, Systems And Methods For Reducing The Concentration Of Carbon Dioxide In Blood. 61/660,013.

Federspiel, W., Russell, A.J., Oh, H., & Kaar, J. (2012). Devices, systems and methods for reducing the concentration of a chemical entity in fluids. 8,323,379.

Federspiel WJ, Frankowski BJ, Yoshida T, & Vernucci PJ. (2011). Oxygen depletion devices and methods for removing oxygen from red blood cells. 13/115,532.

Federspiel, W., Frankowski, B.J., Mack, B.C., Morley, S.W., Rosenberg, M., & Svitek, R.G. (2011). Paracorporeal Respiratory Assist Lung. 7,927,544.

Federspiel, W., Frankowski, B.J., Mack, B.C., Morley, S.W., Rosenberg, M., & Svitek, R.G. (2011). Paracorporeal Respiratory Assist Lung. 13/084100.

Federspiel, W., Russell, A.J., Oh, H., & Kaar, J. (2011). Devices, systems and methods for reducing the concentration of a chemical entity in fluids. 13/280,033.

Federspiel, W., Russell, A.J., Oh, H., & Kaar, J. (2011). Devices, Systems and Methods for Reducing the Concentration of a Chemical Entity in Fluids. 8,043,411.

Federspiel WJ, Kellum JA, & Singbartl K. (2010). Devices Systems and Methods for Cell Modification. 13/500,163.

Federspiel WJ, Yoshida T, Vernucci PJ, Frankowski BJ, & Wheeler Lund L. (2010). Removal of Oxygen from Biological Fluids. 61/230,575.

Federspiel WJ, Yoshida T, Vernucci PJ, Frankowski BJ, & Wheeler Lund L. (2010). Removal of Oxygen from Biological Fluids. PCT/US2010/44045.

Federspiel, W., Russell, A.J., Oh, H., & Kaar, J. (2010). Devices, Systems and Methods for Reducing the Concentration of a Chemical Entity in Fluids. 12/816,455.

Federspiel, W., Russell, A.J., Oh, H., & Kaar, J. (2010). Devices, Systems and Methods for Reducing the Concentration of a Chemical Entity in Fluids. 7,763,097.

Frankowski BJ, Federspiel WJ, Mihelc KM, & Lieber SC. (2009). Intracorporeal Gas Exchange Devices, Systems and Methods. PCT/US2009/033399.

Frankowski BJ, Federspiel WJ, Mihelc KM, & Lieber SC. (2009). Intracorporeal Gas Exchange Devices, Systems and Methods. 12/865,958.

Federspiel, W., Russell, A.J., Oh, H., & Kaar, J. (2007). Devices, Systems and Methods for Reducing the Concentration of a Chemical Entity in Fluids. 11,811,265.

Federspiel, W., Russell, A.J., Oh, H., & Kaar, J. (2007). Devices, Systems and Methods for Reducing the Concentration of a Chemical Entity in Fluids. PCT/US2007/013563.

Federspiel, W., Frankowski, B.J., Mack, B.C., Morley, S.W., Rosenberg, M., & Svitek, R.G. (2006). Paracorporeal Respiratory Assist Lung. 11/408,650.

Federspiel, W., Frankowski, B.J., Mack, B.C., Morley, S.W., Rosenberg, M., & Svitek, R.G. (2006). Paracorporeal Respiratory Assist Lung. PCT/US06/15000.

Hattler BG, Federspiel WJ, & Frankowski BJ. (2006). Percutaneous Respiratory Assist Catheter Incorporating A Spinning Fiber Bundle. 60/688,861.

Hattler BG, Federspiel WJ, & Frankowski BJ. (2006). Percutaneous Respiratory Assist Catheter Incorporating A Spinning Fiber Bundle. PCT/US06/15002.

Frankowski BJ, Federspiel WJ, Golob Jr. JF, & Hattler BG. (2003). Magnetic Guidewires. 10/434,555.

Research interests

Advanced application of fluid...
Cardiovascular and pulmonary...
Combining microfabrication and...
Design and development of membrane...
Design and development of novel...
Developing improved transport...
Development of mathematical and...
Development of oxygen depletion...
Modeling and optimizing artificial...
Respiratory assist and blood...
Respiratory support catheters and...