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Paolo Zunino

Assistant Professor
Mechanical Engineering & Materials Science

about

(2004) Awarded with the SIAM Outstanding Paper Prize by the Society of Industrial and Applied Mathematics, on July 2004 in Portland, Oregon, for the paper A Domain Decomposition Method for Advection-Diffusion Processes with Application to Blood Solutes, by Alfio Quarteroni, Alessandro Veneziani and Paolo Zunino, appeared in the SIAM Journal on Scientific Computing in 2002. The prizes, first awarded in 1999, are given for outstanding papers published in SIAM journals during the three years prior to the year of the award..

PhD, Applied Mathematics, Institute of Analysis and Scientific Computing, 2002 - present

MD, Master in Aerospace Engineering, 1999 - present

Ambartsumyan, I., Khattatov, E., Yotov, I., & Zunino, P. (2018). A Lagrange multiplier method for a Stokes-Biot fluid-poroelastic structure interaction model. NUMERISCHE MATHEMATIK, 140(2), 513-553.Springer Science and Business Media LLC. doi: 10.1007/s00211-018-0967-1.

Nichols, D.A., Sondh, I.S., Little, S.R., Zunino, P., & Gottardi, R. (2018). Design and validation of an osteochondral bioreactor for the screening of treatments for osteoarthritis (vol 20, 18, 2018). BIOMEDICAL MICRODEVICES, 20(2), 39.Springer Science and Business Media LLC. doi: 10.1007/s10544-018-0283-7.

Nichols, D.A., Sondh, I.S., Little, S.R., Zunino, P., & Gottardi, R. (2018). Design and validation of an osteochondral bioreactor for the screening of treatments for osteoarthritis. Biomed Microdevices, 20(1), 18.Springer Science and Business Media LLC. doi: 10.1007/s10544-018-0264-x.

Disser, K., Galdi, G.P., Mazzone, G., & Zunino, P. (2016). Inertial Motions of a Rigid Body with a Cavity Filled with a Viscous Liquid. ARCHIVE FOR RATIONAL MECHANICS AND ANALYSIS, 221(1), 487-526.Springer Science and Business Media LLC. doi: 10.1007/s00205-016-0966-2.

Iannetti, L., D'Urso, G., Conoscenti, G., Cutri, E., Tuan, R.S., Raimondi, M.T., Gottardi, R., & Zunino, P. (2016). Distributed and Lumped Parameter Models for the Characterization of High Throughput Bioreactors. PLOS ONE, 11(9), e0162774.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0162774.

Nabil, M., & Zunino, P. (2016). A computational study of cancer hyperthermia based on vascular magnetic nanoconstructs. R Soc Open Sci, 3(9), 160287.The Royal Society. doi: 10.1098/rsos.160287.

Zunino, P., Tambaca, J., Cutri, E., Canic, S., Formaggia, L., & Migliavacca, F. (2016). Integrated Stent Models Based on Dimension Reduction: Review and Future Perspectives. ANNALS OF BIOMEDICAL ENGINEERING, 44(2), 604-617.Springer Science and Business Media LLC. doi: 10.1007/s10439-015-1459-4.

Bukac, M., Yotov, I., & Zunino, P. (2015). An Operator Splitting Approach for the Interaction Between a Fluid and a Multilayered Poroelastic Structure. NUMERICAL METHODS FOR PARTIAL DIFFERENTIAL EQUATIONS, 31(4), 1054-1100.Wiley. doi: 10.1002/num.21936.

Bukac, M., Yotov, I., Zakerzadeh, R., & Zunino, P. (2015). Effects of Poroelasticity on Fluid-Structure Interaction in Arteries: a Computational Sensitivity Study. Modeling, Simulation and Applications, 14, 197-220.Springer International Publishing. doi: 10.1007/978-3-319-05230-4_8.

Bukac, M., Yotov, I., Zakerzadeh, R., & Zunino, P. (2015). Partitioning strategies for the interaction of a fluid with a poroelastic material based on a Nitsche's coupling approach. COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING, 292, 138-170.Elsevier BV. doi: 10.1016/j.cma.2014.10.047.

Cattaneo, L., & Zunino, P. (2015). Numerical investigation of convergence rates for the FEM approximation of 3D-1D coupled problems. Lecture Notes in Computational Science and Engineering, 103, 727-734. doi: 10.1007/978-3-319-10705-9__72.

Cattaneo, L., & Zunino, P. (2015). Numerical Investigation of Convergence Rates for the FEM Approximation of 3D-1D Coupled Problems. Lecture Notes in Computational Science and Engineering, 103, 727-734.Springer International Publishing. doi: 10.1007/978-3-319-10705-9_72.

Cattaneo, L., Formaggia, L., Iori, G.F., Scotti, A., & Zunino, P. (2015). Stabilized extended finite elements for the approximation of saddle point problems with unfitted interfaces. CALCOLO, 52(2), 123-152.Springer Science and Business Media LLC. doi: 10.1007/s10092-014-0109-9.

Nabil, M., Decuzzi, P., & Zunino, P. (2015). Modelling mass and heat transfer in nano-based cancer hyperthermia. ROYAL SOCIETY OPEN SCIENCE, 2(10), 150447.The Royal Society. doi: 10.1098/rsos.150447.

Cattaneo, L., & Zunino, P. (2014). A computational model of drug delivery through microcirculation to compare different tumor treatments. INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, 30(11), 1347-1371.Wiley. doi: 10.1002/cnm.2661.

Cattaneo, L., & Zunino, P. (2014). COMPUTATIONAL MODELS FOR FLUID EXCHANGE BETWEEN MICROCIRCULATION AND TISSUE INTERSTITIUM. NETWORKS AND HETEROGENEOUS MEDIA, 9(1), 135-159.American Institute of Mathematical Sciences (AIMS). doi: 10.3934/nhm.2014.9.135.

Cho, S.K., & Zunino, P. (2014). Introduction: 31st Annual Gallery of Fluid Motion (Pittsburgh, Pennsylvania, USA, 2013). PHYSICS OF FLUIDS, 26(9), 091101.AIP Publishing. doi: 10.1063/1.4895622.

Morlacchi, S., Chiastra, C., Cutri, E., Zunino, P., Burzotta, F., Formaggia, L., Dubini, G., & Migliavacca, F. (2014). Stent deformation, physical stress, and drug elution obtained with provisional stenting, conventional culotte and Tryton-based culotte to treat bifurcations: a virtual simulation study. EUROINTERVENTION, 9(12), 1441-1453.Europa Digital & Publishing. doi: 10.4244/EIJV9I12A242.

Caputo, M., Chiastra, C., Cianciolo, C., Cutr, E., Dubini, G., Gunn, J., Keller, B., Miglizvacca, F., & Zunino, P. (2013). Simulation of oxygen transfer in stented arteries and correlation with instent restenosis. Int. J. Numer. Meth. Biomed. Engng., 29(12), 1307-1455.

Caputo, M., Chiastra, C., Cianciolo, C., Cutri, E., Dubini, G., Gunn, J., Keller, B., Migliavacca, F., & Zunino, P. (2013). Simulation of oxygen transfer in stented arteries and correlation with in-stent restenosis. INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, 29(12), 1373-1387.Wiley. doi: 10.1002/cnm.2588.

Cutri, E., Zunino, P., Morlacchi, S., Chiastra, C., & Migliavacca, F. (2013). Drug delivery patterns for different stenting techniques in coronary bifurcations: a comparative computational study. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 12(4), 657-669.Springer Science and Business Media LLC. doi: 10.1007/s10237-012-0432-5.

Galdi, G.P., Mazzone, G., & Zunino, P. (2013). Intertial motions of a rigid body with a cavity filled with a viscous liquid. Comptes Rendus Mcanique, 341(11-12), 760-765.

Galdi, G.P., Mazzone, G., & Zunino, P. (2013). Inertial motions of a rigid body with a cavity filled with a viscous liquid. COMPTES RENDUS MECANIQUE, 341(11-12), 760-765.Elsevier BV. doi: 10.1016/j.crme.2013.10.001.

Zunino, P. (2013). Analysis of backward Euler/extended finite element discretization of parabolic problems with moving interfaces. COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING, 258, 152-165.Elsevier BV. doi: 10.1016/j.cma.2013.02.010.

DʼAngelo, C., & Zunino, P. (2012). Numerical approximation with Nitscheʼs coupling of transient Stokesʼ/Darcyʼs flow problems applied to hemodynamics. Applied Numerical Mathematics, 62(4), 378-395.Elsevier BV. doi: 10.1016/j.apnum.2011.03.001.

Porpora, A., Zunino, P., Vergara, C., & Piccinelli, M. (2012). Numerical treatment of boundary conditions to replace lateral branches in hemodynamics. INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, 28(12), 1165-1183.Wiley. doi: 10.1002/cnm.2488.

Biscari, P., Minisini, S., Pierotti, D., Verzini, G., & Zunino, P. (2011). Controlled Release with Finite Dissolution Rate. SIAM Journal on Applied Mathematics, 71(3), 731-752.Society for Industrial & Applied Mathematics (SIAM). doi: 10.1137/100790288.

Burman, E., & Zunino, P. (2011). Numerical Approximation of Large Contrast Problems with the Unfitted Nitsche Method. In Lecture Notes in Computational Science and Engineering. 85 LNCSE, (pp. 227-282).Springer Berlin Heidelberg. doi: 10.1007/978-3-642-23914-4_4.

D'Angelo, C., & Zunino, P. (2011). Robust numerical approximation of coupled Stokes' and Darcy's flows applied to vascular hemodynamics and biochemical transport. ESAIM: Mathematical Modelling and Numerical Analysis, 45(3), 447-476.EDP Sciences. doi: 10.1051/m2an/2010062.

D'Angelo, C., Zunino, P., Porpora, A., Morlacchi, S., & Migliavacca, F. (2011). Model Reduction Strategies Enable Computational Analysis of Controlled Drug Release from Cardiovascular Stents. SIAM Journal on Applied Mathematics, 71(6), 2312-2333.Society for Industrial & Applied Mathematics (SIAM). doi: 10.1137/10081695x.

Dubini, G., Ambrosi, D., Bagnoli, P., Boschetti, F., Caiani, E.G., Chiastra, C., Conti, C.A., Corsini, C., Costantino, M.L., D'Angelo, C., Formaggia, L., Fumero, R., Gastaldi, D., Migliavacca, F., Morlacchi, S., Nobile, F., Pennati, G., Petrini, L., Quarteroni, A., Redaelli, A., Stevanell, M., Veneziani, A., Vergara, C., Votta, E., Wu, W., & Zunino, P. (2011). Trends in biomedical engineering: Focus on patient specific modeling and life support systems. Journal of Applied Biomaterials and Biomechanics, 9(2), 109-117.

Dubini, G., Ambrosi, D., Bagnoli, P., Boschetti, F., Caiani, E.G., Chiastra, C., Conti, C.A., Corsini, C., Costantino, M.L., D'Angelo, C., Formaggia, L., Fumero, R., Gastaldi, D., Migliavacca, F., Morlacchi, S., Nobile, F., Pennati, G., Petrini, L., Quarteroni, A., Redaelli, A., Stevanella, M., Veneziani, A., Vergara, C., Votta, E., Wu, W., & Zunino, P. (2011). Trends in biomedical engineering: focus on Patient Specific Modeling and Life Support Systems. J Appl Biomater Biomech, 9(2), 109-117.SAGE Publications. doi: 10.5301/JABB.2011.8585.

Sacco, R., Causin, P., Zunino, P., & Raimondi, M.T. (2011). A multiphysics/multiscale 2D numerical simulation of scaffold-based cartilage regeneration under interstitial perfusion in a bioreactor. Biomech Model Mechanobiol, 10(4), 577-589.Springer Science and Business Media LLC. doi: 10.1007/s10237-010-0257-z.

Tanzi, M.C., Bozzini, S., Candiani, G., Cigada, A., de NArdo, L., Far, S., Ganazoli, F., Gastaldi, D., Levi, M., Metrangolo, P., Migliavacca, F., Osellame, R., Petrini, P., Raffaini, G., Resnati, G., Vena, P., Vesestini, S., & Zunino, P. (2011). Trends in biomedical engineering: Focus on smart bio-materials and drug delivery. Journal of Applied Biomaterials and Biomechanics, 9(2), 87-97.

Tanzi, M.C., Bozzini, S., Candiani, G., Cigada, A., De Nardo, L., Farè, S., Ganazzoli, F., Gastaldi, D., Levi, M., Metrangolo, P., Migliavacca, F., Osellame, R., Petrini, P., Raffaini, G., Resnati, G., Vena, P., Vesentini, S., & Zunino, P. (2011). Trends in biomedical engineering: focus on Smart Bio-Materials and Drug Delivery. J Appl Biomater Biomech, 9(2), 87-97.SAGE Publications. doi: 10.5301/JABB.2011.8563.

Zunino, P., Cattaneo, L., & Colciago, C.M. (2011). An unfitted interface penalty method for the numerical approximation of contrast problems. Applied Numerical Mathematics, 61(10), 1059-1076.Elsevier BV. doi: 10.1016/j.apnum.2011.06.005.

FORMAGGIA, L., MINISINI, S., & ZUNINO, P. (2010). MODELING POLYMERIC CONTROLLED DRUG RELEASE AND TRANSPORT PHENOMENA IN THE ARTERIAL TISSUE. Mathematical Models and Methods in Applied Sciences, 20(10), 1759-1786.World Scientific Pub Co Pte Lt. doi: 10.1142/s0218202510004787.

Formaggia, L., Mlnisini, S., & Zunino, P. (2010). Stent a rilascio di farmaco: Una storia di successo per la matematica applicata. Matematica nella Societa e nella Cultura, 3(2), 181-200.

Soares, J.S., & Zunino, P. (2010). A mixture model for water uptake, degradation, erosion and drug release from polydisperse polymeric networks. Biomaterials, 31(11), 3032-3042.Elsevier BV. doi: 10.1016/j.biomaterials.2010.01.008.

D'Angelo, C., & Zunino, P. (2009). A Finite Element Method Based on Weighted Interior Penalties for Heterogeneous Incompressible Flows. SIAM Journal on Numerical Analysis, 47(5), 3990-4020.Society for Industrial & Applied Mathematics (SIAM). doi: 10.1137/080726318.

Ern, A., Stephansen, A.F., & Zunino, P. (2009). A discontinuous Galerkin method with weighted averages for advection-diffusion equations with locally small and anisotropic diffusivity. IMA Journal of Numerical Analysis, 29(2), 235-256.Oxford University Press (OUP). doi: 10.1093/imanum/drm050.

Perktold, K., Prosi, M., & Zunino, P. (2009). Mathematical models of mass transfer in the vascular walls. In Cardiovascular Mathematics. 1, (pp. 243-278).Springer Milan. doi: 10.1007/978-88-470-1152-6_7.

Salsa, S., Vegni, F.M.G., Zaretti, A., & Zunino, P. (2009). Invito alle equazioni a derivate parziali: Metodi,modelli e simulazioni. UNITEXT - La Matematica per il 3 piu 2, 44.

Zunino, P. (2009). Numerical approximation of incompressible flows with net flux defective boundary conditions by means of penalty techniques. Computer Methods in Applied Mechanics and Engineering, 198(37-40), 3026-3038.Elsevier BV. doi: 10.1016/j.cma.2009.05.010.

Zunino, P. (2009). Discontinuous Galerkin Methods Based on Weighted Interior Penalties for Second Order PDEs with Non-smooth Coefficients. Journal of Scientific Computing, 38(1), 99-126.Springer Science and Business Media LLC. doi: 10.1007/s10915-008-9219-3.

Zunino, P., D’Angelo, C., Petrini, L., Vergara, C., Capelli, C., & Migliavacca, F. (2009). Numerical simulation of drug eluting coronary stents: Mechanics, fluid dynamics and drug release. Computer Methods in Applied Mechanics and Engineering, 198(45-46), 3633-3644.Elsevier BV. doi: 10.1016/j.cma.2008.07.019.

Vergara, C., & Zunino, P. (2008). Multiscale Boundary Conditions for Drug Release from Cardiovascular Stents. Multiscale Modeling & Simulation, 7(2), 565-588.Society for Industrial & Applied Mathematics (SIAM). doi: 10.1137/07070214x.

Migliavacca, F., Gervaso, F., Prosi, M., Zunino, P., Minisini, S., Formaggia, L., & Dubini, G. (2007). Expansion and drug elution model of a coronary stent. Comput Methods Biomech Biomed Engin, 10(1), 63-73.Informa UK Limited. doi: 10.1080/10255840601071087.

Burman, E., & Zunino, P. (2006). A Domain Decomposition Method Based on Weighted Interior Penalties for Advection‐Diffusion‐Reaction Problems. SIAM Journal on Numerical Analysis, 44(4), 1612-1638.Society for Industrial & Applied Mathematics (SIAM). doi: 10.1137/050634736.

CALABRÒ, F., & ZUNINO, P. (2006). ANALYSIS OF PARABOLIC PROBLEMS ON PARTITIONED DOMAINS WITH NONLINEAR CONDITIONS AT THE INTERFACE: APPLICATION TO MASS TRANSFER THROUGH SEMI-PERMEABLE MEMBRANES. Mathematical Models and Methods in Applied Sciences, 16(04), 479-501.World Scientific Pub Co Pte Lt. doi: 10.1142/s0218202506001236.

Corno, A.F., Prosi, M., Fridez, P., Zunino, P., Quarteroni, A., & von Segesser, L.K. (2006). The non-circular shape of FloWatch-PAB prevents the need for pulmonary artery reconstruction after banding. Computational fluid dynamics and clinical correlations. Eur J Cardiothorac Surg, 29(1), 93-99.Oxford University Press (OUP). doi: 10.1016/j.ejcts.2005.10.029.

Zunino, P., & Calabro, F. (2006). Global existence of strong solutions of parabolic problems on partitioned domains with nonlinear conditions at the interface. Applications to mass transfer processes through semi-permeable membranes. Math. Mod. Meth. Appl. Sci., 16, 479-501.

Prosi, M., Zunino, P., Perktold, K., & Quarteroni, A. (2005). Mathematical and numerical models for transfer of low-density lipoproteins through the arterial walls: a new methodology for the model set up with applications to the study of disturbed lumenal flow. J Biomech, 38(4), 903-917.Elsevier BV. doi: 10.1016/j.jbiomech.2004.04.024.

Zunino, P. (2004). Multidimensional Pharmacokinetic Models Applied to the Design of Drug-Eluting Stents. Cardiovascular Engineering, 4(2), 181-191.Springer Science and Business Media LLC. doi: 10.1023/b:care.0000031547.39178.cb.

Quarteroni, A., Veneziani, A., & Zunino, P. (2002). Mathematical and Numerical Modeling of Solute Dynamics in Blood Flow and Arterial Walls. SIAM Journal on Numerical Analysis, 39(5), 1488-1511.Society for Industrial & Applied Mathematics (SIAM). doi: 10.1137/s0036142900369714.

Quarteroni, A., Veneziani, A., & Zunino, P. (2002). A Domain Decomposition Method for Advection-Diffusion Processes with Application to Blood Solutes. SIAM Journal on Scientific Computing, 23(6), 1959-1980.Society for Industrial & Applied Mathematics (SIAM). doi: 10.1137/s1064827500375722.

Zunino, P., Quarteroni, A., & Veneziani, A. (2002). A Domain Decomposition Method for Advection-Diffusion Processes with Applications to Blood Solutes. (awarded with the SIAM Outstanding Paper Prized 2004). SIAM J. Sci. Comput., 23, 1959-1980.

Formaggia, L., Perotto, S., & Zunino, P. (2001). An anisotropic a-posteriori error estimate for a convection-diffusion problem. Computing and Visualization in Science, 4(2), 99-104.Springer Science and Business Media LLC. doi: 10.1007/s007910100061.

Ambartsumyan, I., Khattatov, E., Yotov, I., & Zunino, P. (2015). Simulation of Flow in Fractured Poroelastic Media: A Comparison of Different Discretization Approaches. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 9045, (pp. 3-14).Springer International Publishing. doi: 10.1007/978-3-319-20239-6_1.

Valentin, A., Notaro, D., Zunino, P., Allen, R., Ambrosi, D., Wang, Y., & Robertson, A.M. (2015). Theory and application of arterial tissue in-host remodelling. In Annu Int Conf IEEE Eng Med Biol Soc, 2015, (pp. 1869-1872).IEEE.United States. doi: 10.1109/EMBC.2015.7318746.

Nabil, M., Zunino, P., & Cattaneo, L. (2014). A computational study of microscale flow and mass transport in vasculatized tumors. In 2014 21th Iranian Conference on Biomedical Engineering (ICBME), (pp. 23-28).IEEE. doi: 10.1109/icbme.2014.7043887.

Zakerzadeh, R., & Zunino, P. (2014). Fluid-structure interaction in arteries with a poroelastic wall model. In 2014 21th Iranian Conference on Biomedical Engineering (ICBME), (pp. 35-39).IEEE. doi: 10.1109/icbme.2014.7043889.

Zunino, P., Vesentini, S., Porpora, A., Soares, J.S., Gautieri, A., & Redaelli, A. (2012). Multiscale computational analysis of degradable polymers. In Modeling, Simulation and Applications, 5, (pp. 333-361).Springer Milan. doi: 10.1007/978-88-470-1935-5_11.

Soares, J.A., & Zunino, P. (2010). A Multiscale Mixture Model for Polymer Degradation and Erosion. In ASME 2010 Summer Bioengineering Conference, Parts A and B, (PARTS A AND B), (pp. 113-114).American Society of Mechanical Engineers. doi: 10.1115/sbc2010-19251.

Zunino, P. (2009). BAIL 2008 - Boundary and Interior Layers. (pp. 295-304).Springer Berlin Heidelberg. doi: 10.1007/978-3-642-00605-0.

Zunino, P. (2009). Energy Norm A-Posteriori Error Estimates for a Discontinuous Galerkin Scheme Applied to Elliptic Problems with an Interface. In Lecture Notes in Computational Science and Engineering, 69 LNCSE, (pp. 295-304).Springer Berlin Heidelberg. doi: 10.1007/978-3-642-00605-0_25.

Zunino, P. (2008). Mortar and Discontinuous Galerkin Methods Based on Weighted Interior Penalties. In Lecture Notes in Computational Science and Engineering, 60, (pp. 321-327).Springer Berlin Heidelberg. doi: 10.1007/978-3-540-75199-1_38.

Formaggia, L., Nobile, F., Quarteroni, A., Veneziani, A., & Zunino, P. (2000). Advances on numerical modelling of blood flow problems. In European Congress on Computational Methods in Applied Sciences and Engineering, ECCOMAS 2000.