Abigail Allen

Faculty Mentor: Partha Roy

Research:

Our lab focuses on studying the role of the cytoskeleton, specifically the actin-binding protein profilin-1 (pfn1) in different diseases (i.e. cancer, atherosclerosis). Particularly, my research focuses on the role of variable pfn1 expression in vascularization, and how this influences angiogenesis and, potentially, immune recruitment to sites of damage.

Publications:

• Russell, Kira L., BS; Gorgulho, Carolina Mendonça, BS; Allen, Abigail; Vakaki, Marianna, BS; Wang, Yue, MD; Facciabene, Andrea, PhD; Lee, Daniel, MD, PhD; Roy, Partha, PhD; Buchser, William J., PhD; Appleman, Leonard J., MD, PhD; Maranchie, Jodi, MD; Storkus, Walter J., PhD; Lotze, Michael T., MD. “Inhibiting Autophagy in Renal Cell Cancer and the Associated Tumor Endothelium” The Cancer Journal, Vol. 25, Issue 3, p. 165-77. May/June 2019.

Presentations:

• Abigail E. Allen, Mahboubeh S. Noori, Kelly D. McCall, Stephen C. Bergmeier, and Douglas J. Goetz. “Small Molecule Inhibition of IFN-γ-Induced Major Histocompatibility Complex Class II Expression by Thyroid Cells,” Experimental Biology; FASEB Journal, Vol. 32 No. 1, April 20, 2018.

Honors and Awards:

• Bevier Award
• Achievement Rewards for College Scientists Foundation Scholar

Ms. Allen's research focuses on the role of variable pfn1 expression in vascularization, and how this influences angiogenesis and, potentially, immune recruitment to sites of damage.