Salim Olia

Faculty Mentor: Marina Kameneva

Research:Mr. Olia's current research on the development of the next generation pediatric ventricular assist devices (PVAD) consists of two primary goals: 1) the optimization of in-vitro and in-vivo test parameters for testing and comparing PVADs and 2) designing a smart PVAD controller to calculate patient-pump performance indices in order to detect and predict pathological conditions and events. Preliminary studies have been performed and presented examining the effects of pre-load on outgassing and hemolysis in PVADs. Work has also continued on addressing the concerns of blood volume versus flow rate during in vitro blood trauma testing of PVADs. As the primary graduate student in collaboration with the FDA conducting validation studies for computational blood damage models, further examination was performed looking at hemolysis within small scale nozzle and orifice geometries. In order to enable testing of relevant blood parameters during pediatric clinical trials, efforts have been made to miniaturize these tests to reduce blood volume required from the patients. Finally, software development for the smart PVAD controller has continued with the optimization of system processes and background subroutines in order to minimize overhead and lag.     

Publications:  

• Maul TM, Kocyildirim E, Johnson CA, Daly AR, Olia SE, Woolley JR, Synder S, Bengston SG, Kameneva MV, Antaki JF, Wagner WR, Borovetz HS, Wearden PD. "PediaFlow Consortium. Preclinical Performance of the PediaFlow Pediatric  
• Maul TM, Kocyildirim E, Marks JD, Bengston SG, Olia SE, Callahan PM, Kameneva MV, Franklin S, Borovetz HS, Dasse KA, Wearden PD. "Pre-clinical Implants of the Levitronix PediVAS® Pediatric Ventricular Assist Device - Strategy for Regulatory Approval". Cardiovascular Engineering and Technology2012( ): , 2012  

Conferences:  

• ASAIO Conference, Baltimore, MD. United States, 5/1/2010.
  • Salim Olia, Amanda Daly, Rui Zhao, Shawn Bengston, Timothy Maul, Peter Wearden, James Antaki, Harvey, "HEMORHEOLOGICAL EVALUATION OF THE 3rd GEN. PEDIAFLOW PEDIATRIC VAD."
   
• Gordon Research Conference, Waterville, NH, United States, 06/2011 
• American Heart Association 21st Annual Fellows Research Day, Pittsburgh, PA. United States, 2/15/2013. 
• MIRM Retreat, Nemacolin, PA. United States, 3/7/2013.
• American Society for Artificial Internal Organs 59th Annual Conference, Chicago, IL. Unites States, 6/1/2013.
• American Society for Artificial Internal Organs (ASAIO) 59th Annual Conference, Chicago, IL. United States, 6/12/2013.
• Gordon Research Conference: Assisted Circulation, Lucca, Italy. 6/13/2013.
  • Olia SE, Maul TM, Snyder ST, Shankarraman V, Paden D, Wearden PD, Wagner WR, Trumble DR, Antaki JF, "Cannula and Graft Considerations for the PediaFlow® Pediatric Rotary Blood Pump."
   
• Gordon Research Seminar and Conference: Assisted Circulation, Lucca, Italy. 6/22/2013.
  • Olia SE, Maul TM, Snyder ST, Wu J, Paden DB, Ricci M, Wearden PD, Trumble DR, Antaki JF, Borovetz HS, "Challenges of Pediatric VAD Design: The PediaFlow® Experience."